摘要:
A method of improving the polymerization rate and physical properties of a polymerizable methacrylate-containing hydrogel composition by decreasing the time required to achieve the polymerization peak time.
摘要:
A novel silicone-containing, hydrogel material is disclosed comprising an acrylic-capped polysiloxane prepolymer, polymerized with a bulky polysiloxanylalkyl (meth)acrylate monomer and at least one hydrophilic monomer.
摘要:
A process for preparing silicone hydrogel contact lenses where machining operations are employed to produce a lens having a desired final shape. The silicone hydrogel contact lenses are prepared by:providing a monomeric mixture comprising a silicone-containing monomer, a hydrophilic monomer and an organic diluent;charging the mixture to a mold and curing the formulation in the mold to obtain a shaped article;removing organic diluent from the shaped article to improve machineability of the article; andmachining the shaped article to obtain a contact lens having a desired configuration.
摘要:
Provided are surface modified contact lenses formed from one or more fumaric-or itaconic-containing prepolymers having polymerizable functionality that is complimentary to polymerizable hydrophilic polymers.
摘要:
Provided are surface modified contact lenses formed from one or more fumaric- or itaconic-containing prepolymers having polymerizable functionality that is complimentary to polymerizable hydrophilic polymers.
摘要:
Polysiloxanes having vinyl or epoxy functionality. The polysiloxanes are used to form polymer-based materials having properties particularly suited for biomedical device applications. The polysiloxanes are of general formula I: wherein R is a C2-10 alkenyl, a C2-10 alkyl with an epoxy group or a C5-C7cycloalkyl with an epoxy group; R2, R3 and R4 are each independently selected from the group consisting of hydrogen, C1-4 alkyl, C1-4 fluoroalkyl, optionally substituted phenyl and optionally substituted benzyl; A is —OH or —NHR5, wherein R5 is hydrogen or a C1-3 alkyl; and B is —R1-A or —R6, wherein R1 is a linking group having an alkylene group with 2 to 8 carbon atoms wherein the alkylene group optionally includes ether, urethane or ureido linkages; and R6 is selected from the group consisting of C1-4 alkyl, optionally substituted phenyl or optionally substituted benzyl; and m and n are integers with an m:n ratio from 30:1 to 3:1.
摘要:
A surface modified biomedical device is provided comprising a biomedical device having a coating on at least a portion thereof, the coating comprising one or more hydrophilic polymers having one or more non-ethylenically-unsaturated carboxylic acid terminated groups.
摘要:
Provided are surface modified contact lenses formed from one or more fumaric- or itaconic-containing prepolymers having polymerizable functionality that is complimentary to polymerizable hydrophilic polymers.
摘要:
Provided are surface modified contact lenses formed from one or more fumaric- or itaconic-containing prepolymers having polymerizable functionality that is complimentary to polymerizable hydrophilic polymers.
摘要:
A polysiloxane copolymer that is useful for forming biomedical devices comprises blocks (I) and (II) and is terminated at each end with an ethylenically unsaturated radical: (*Dii*Diol*Dii*PS)x (I) (*Dii*PS)y (II) wherein: each Dii is independently a diradical residue of a diisocyanate; each Diol is independently a diradical residue of a diol having 1 to 10 carbon atoms; each PS is independently a diradical residue of a polysiloxane-containing diol or diamine; each * is independently —NH—CO—NH—, —NH—COO— or —OCO—NH—: x represents the number of blocks (I) and is at least 2, and y represents the number of blocks (II) and is at least 1.