Method of curing methacrylate-based compositions
    61.
    发明授权
    Method of curing methacrylate-based compositions 失效
    固化基于甲基丙烯酸酯的组合物的方法

    公开(公告)号:US5610204A

    公开(公告)日:1997-03-11

    申请号:US652182

    申请日:1996-05-23

    申请人: Yu-Chin Lai

    发明人: Yu-Chin Lai

    CPC分类号: C08F20/28 G02B1/043

    摘要: A method of improving the polymerization rate and physical properties of a polymerizable methacrylate-containing hydrogel composition by decreasing the time required to achieve the polymerization peak time.

    摘要翻译: 通过减少实现聚合峰值时间所需的时间来改善可聚合的含甲基丙烯酸酯的水凝胶组合物的聚合速率和物理性能的方法。

    Process for making silicone containing hydrogel lenses
    63.
    发明授权
    Process for making silicone containing hydrogel lenses 失效
    制造含硅氧烷水凝胶镜片的方法

    公开(公告)号:US5260000A

    公开(公告)日:1993-11-09

    申请号:US924214

    申请日:1992-08-03

    摘要: A process for preparing silicone hydrogel contact lenses where machining operations are employed to produce a lens having a desired final shape. The silicone hydrogel contact lenses are prepared by:providing a monomeric mixture comprising a silicone-containing monomer, a hydrophilic monomer and an organic diluent;charging the mixture to a mold and curing the formulation in the mold to obtain a shaped article;removing organic diluent from the shaped article to improve machineability of the article; andmachining the shaped article to obtain a contact lens having a desired configuration.

    摘要翻译: 一种制备硅酮水凝胶隐形眼镜的方法,其中采用加工操作来制造具有所需最终形状的透镜。 硅氧水凝胶隐形眼镜通过以下方式制备:提供包含含硅氧烷的单体,亲水性单体和有机稀释剂的单体混合物; 将混合物装入模具中并固化模具中的配方以获得成型制品; 从成形制品中除去有机稀释剂以提高制品的可加工性; 并加工成形制品以获得具有期望构造的隐形眼镜。

    POLYSILOXANES AND POLYSILOXANE PREPOLYMERS WITH VINYL OR EPOXY FUNCTIONALITY
    66.
    发明申请
    POLYSILOXANES AND POLYSILOXANE PREPOLYMERS WITH VINYL OR EPOXY FUNCTIONALITY 有权
    具有乙烯基或环氧官能团的多异氰酸酯和聚硅氧烷预聚物

    公开(公告)号:US20090227804A1

    公开(公告)日:2009-09-10

    申请号:US12042378

    申请日:2008-03-05

    IPC分类号: C07D303/02

    摘要: Polysiloxanes having vinyl or epoxy functionality. The polysiloxanes are used to form polymer-based materials having properties particularly suited for biomedical device applications. The polysiloxanes are of general formula I: wherein R is a C2-10 alkenyl, a C2-10 alkyl with an epoxy group or a C5-C7cycloalkyl with an epoxy group; R2, R3 and R4 are each independently selected from the group consisting of hydrogen, C1-4 alkyl, C1-4 fluoroalkyl, optionally substituted phenyl and optionally substituted benzyl; A is —OH or —NHR5, wherein R5 is hydrogen or a C1-3 alkyl; and B is —R1-A or —R6, wherein R1 is a linking group having an alkylene group with 2 to 8 carbon atoms wherein the alkylene group optionally includes ether, urethane or ureido linkages; and R6 is selected from the group consisting of C1-4 alkyl, optionally substituted phenyl or optionally substituted benzyl; and m and n are integers with an m:n ratio from 30:1 to 3:1.

    摘要翻译: 具有乙烯基或环氧官能团的聚硅氧烷。 聚硅氧烷用于形成具有特别适用于生物医学装置应用的特性的聚合物基材料。 聚硅氧烷具有通式I:其中R是C2-10烯基,具有环氧基的C2-10烷基或具有环氧基的C5-C7环烷基; R 2,R 3和R 4各自独立地选自氢,C 1-4烷基,C 1-4氟烷基,任选取代的苯基和任选取代的苄基; A是-OH或-NHR 5,其中R 5是氢或C 1-3烷基; 并且B是-R1-A或-R6,其中R1是具有2至8个碳原子的亚烷基的连接基团,其中亚烷基任选地包括醚,氨基甲酸酯或脲基键; 并且R 6选自C 1-4烷基,任选取代的苯基或任选取代的苄基; m和n为30:1〜3:1的m:n比的整数。

    SURFACE MODIFIED BIOMEDICAL DEVICES
    67.
    发明申请
    SURFACE MODIFIED BIOMEDICAL DEVICES 审中-公开
    表面改性生物医学装置

    公开(公告)号:US20090156745A1

    公开(公告)日:2009-06-18

    申请号:US12329710

    申请日:2008-12-08

    IPC分类号: C08L39/06 C08F26/10 G02C7/04

    摘要: A surface modified biomedical device is provided comprising a biomedical device having a coating on at least a portion thereof, the coating comprising one or more hydrophilic polymers having one or more non-ethylenically-unsaturated carboxylic acid terminated groups.

    摘要翻译: 提供了表面改性的生物医学装置,其包括在其至少一部分上具有涂层的生物医学装置,所述涂层包含一种或多种具有一个或多个非烯属不饱和羧酸端基的亲水性聚合物。

    Polysiloxane prepolymers for biomedical devices
    70.
    发明授权
    Polysiloxane prepolymers for biomedical devices 失效
    用于生物医学器件的聚硅氧烷预聚物

    公开(公告)号:US07423074B2

    公开(公告)日:2008-09-09

    申请号:US11292817

    申请日:2005-12-02

    IPC分类号: G02B1/04 C08F290/06

    摘要: A polysiloxane copolymer that is useful for forming biomedical devices comprises blocks (I) and (II) and is terminated at each end with an ethylenically unsaturated radical: (*Dii*Diol*Dii*PS)x   (I) (*Dii*PS)y   (II) wherein: each Dii is independently a diradical residue of a diisocyanate; each Diol is independently a diradical residue of a diol having 1 to 10 carbon atoms; each PS is independently a diradical residue of a polysiloxane-containing diol or diamine; each * is independently —NH—CO—NH—, —NH—COO— or —OCO—NH—: x represents the number of blocks (I) and is at least 2, and y represents the number of blocks (II) and is at least 1.

    摘要翻译: 可用于形成生物医学装置的聚硅氧烷共聚物包括嵌段(I)和(II),并且在每一端用烯属不饱和基团封端:<?在线配方说明=“在线式”末端=“铅 (* Dii * Diol * Dii * PS)(I)<?in-line-formula description =“In-line Formulas”end =“tail”?> <? line-formula description =“In-line Formulas”end =“lead”?>(* Dii * PS)(II)<?in-line-formula description =“In-line Formulas” end =“tail”?>其中:每个Dii独立地是二异氰酸酯的双基残基; 每个二醇独立地是具有1至10个碳原子的二元醇的双基残基; 每个PS独立地是含聚硅氧烷的二醇或二胺的双基残基; 每个*独立地是-NH-CO-NH-,-NH-COO-或-OCO-NH-:x表示嵌段(I)的数量并且至少为2,y表示嵌段(II)和 至少是1。