摘要:
Furo[3,2-c]Pyridine and Thieno[3,2-c]pyridine compounds of Formula I, and pharmaceutically acceptable salts thereof, preparation, intermediates, pharmaceutical compositions, and use, such as in disease treatment, including cancers, including conditions in which EMT is involved, including conditions mediated by protein kinase activity such as RON and/or MET.
摘要:
Compounds of Formula I, as shown below and defined herein: (I) pharmaceutically acceptable salts, synthesis, intermediates, formulations, and methods of disease treatment therewith, including cancers mediated at least in part by Ron and/or Met.
摘要:
Microfluidic devices are described that include a rigid base layer, and an elastomeric layer on the base layer. The elastomeric layer may include at least part of a fluid channel for transporting a liquid reagent, and a vent channel that accepts gas diffusing through the elastomeric layer from the flow channel and vents it out of the elastomeric layer. The devices may also include a mixing chamber fluidly connected to the fluid channel, and a control channel overlapping with a deflectable membrane that defines a portion of the flow channel, where the control channel may be operable to change a rate at which the liquid reagent flows through the fluid channel. The devices may further include a rigid plastic layer on the elastomeric layer.
摘要:
A code stream conversion system and method, a code stream identifying unit and a solution determining unit are provided. The code stream conversion method includes: receiving an original code stream format obtained by parsing an original code stream; and determining a transcoding solution according to a target code stream format and the original code stream format, and using the original code stream format to decode the original code stream and using the target code stream format to encode a decoded code stream according to the transcoding solution, thus completing code stream conversion, and obtaining a target code stream corresponding to the target code stream format. Through the code stream conversion system and method, the original code stream is parsed and the transcoding solution is determined, thus achieving mutual conversion between a three-dimensional video code stream and a planar video code stream.
摘要:
A rotor blade for a wind turbine is disclosed. The rotor blade includes a root, a tip, and a body extending from the root, the body including a pressure side and a suction side extending between a leading edge and a trailing edge. The rotor blade further includes a winglet extending between the body and the tip, the winglet including a pressure side and a suction side extending between a leading edge and a trailing edge. The winglet further includes a transition section and defines a height, a sweep angle, an outboard cant angle, and a twist angle. The sweep angle, the outboard cant angle, and the twist angle change continuously throughout the transition section.
摘要:
The invention provides a method of efficiently producing branched, cyclic glycerol-based polyols with a co-product as anti-biodegrading agent from inexpensive readily available glycerol monomer. The method involves polymerizing glycerol or glycerol with at least another monomer to multiple other monomers in the presence of particular amount of a strong base as the catalyst under a particular distillation environment. The polyol produced by the inventive method is beneficial of reducing scales in Bayer liquid for aluminum production process and improving brightness of coated paper substrates without greening effect.
摘要:
A binary image reconstruction method is provided to identify metal objects in a computer tomography (CT) image. The method includes providing a suitably programmed computer, providing a CT image, where the CT image includes intensity data, and the suitably programmed computer is used to determine a first range of attenuation coefficient values and a second range of attenuation coefficient values in the intensity data, where when a difference between the first range of attenuation coefficient values and the second range of attenuation coefficient values is less than a pre-determined gradient threshold value, a boundary of a metal object in the CT image is determined.
摘要:
A method and device for controlling a code rate are provided, and this application relates to a video communication technology. The method for controlling a code rate includes the following steps. An output target bit of a current frame is acquired, where the current frame is a currently processed input frame. A target quantization parameter is acquired according to the output target bit by utilizing a nonlinear code rate control model. The present invention is applicable to transcoding between compressed videos.
摘要:
Disclosed is a process for preparing isopimaric acid, comprising the following steps: First step: dissolving thermally isomerized rosin in acetone, adding in drops a solution of isobutanolamine in acetone to form a precipitate, standing, filtering, washing with ethanol, and drying to obtain crude ammonium salt of isopimaric acid; recrystallizing the crude ammonium salt of isopimaric acid according to multi-recrystallization, and drying to obtain purified crystal of ammonium salt of isopimaric acid; Second step: dissolving the purified crystal of ammonium salt of isopimaric acid obtained in the first step in ether, adding hydrochloric acid in portions until the crystal of ammonium salt of isopimaric acid disappears, removing a water layer and washing the ether layer with water to neutral, evaporating the ether, dissolving the residue in acetone, adding water slowly into the solution dropwise until crystals cease to grow, then filtering and drying to obtain purified isopimaric acid.
摘要:
A method and a device for processing data in a dedicated physical data channel, comprising, when data on which softer handover is performed is extended DPDCH data, sending, after completing the softer merging of the data for one timeslot, a request for secondary despread, where the request contains channel numbers; acquiring the request for secondary despread, determining channels according to the channel numbers contained in the request for secondary despread, determining a channel having the highest priority from the channels according to a predetermined channel priority order, and secondarily despreading, framing and outputting data of the channel having the highest priority. Due to the arrangement of the extended DPDCH, embodiments of this invention process the data carried by the extended DPDCH at the frequency of timeslots, and thus reduce the time delay of the second despreading and support services having higher requirements for logic processing delay without affecting the process for the existing normal DPDCH data.