Method of screening for ATP synthase Fo subunit
    62.
    发明授权
    Method of screening for ATP synthase Fo subunit 失效
    筛选ATP合酶Fo亚基的方法

    公开(公告)号:US5948625A

    公开(公告)日:1999-09-07

    申请号:US94080

    申请日:1998-06-09

    CPC分类号: C12N9/14 A61K38/00

    摘要: The present invention provides a human ATP synthase d subunit (ASYSD) and polynucleotides which encode ASYSD. The invention also provides expression vectors, host cells, agonists, antisense molecules, antibodies, or antagonists. The invention also provides methods for producing ASYSD and for treating disorders associated with expression of ASYSD.

    摘要翻译: 本发明提供了人ATP合成酶d亚基(ASYSD)和编码ASYSD的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,反义分子,抗体或拮抗剂。 本发明还提供了用于产生ASYSD和用于治疗与ASYSD表达相关的疾病的方法。

    Amino acid permease homolog
    64.
    发明授权
    Amino acid permease homolog 失效
    氨基酸通透酶同源物

    公开(公告)号:US5942399A

    公开(公告)日:1999-08-24

    申请号:US73362

    申请日:1998-05-06

    CPC分类号: C07K14/705 A61K38/00

    摘要: The invention provides a human amino acid permease homolog (AAPH) and polynucleotides which identify and encode AAPH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of AAPH.

    摘要翻译: 本发明提供了人氨基酸通透酶同源物(AAPH)和识别和编码AAPH的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与AAPH表达相关的紊乱的方法。

    Polynucleotides encoding a human integral membrane protein
    67.
    发明授权
    Polynucleotides encoding a human integral membrane protein 失效
    编码人体内膜蛋白的多核苷酸

    公开(公告)号:US5932420A

    公开(公告)日:1999-08-03

    申请号:US892690

    申请日:1997-07-14

    CPC分类号: C07K14/47 A61K38/00

    摘要: The invention provides a new human integral membrane protein (NIMPH) and polynucleotides which identify and encode NIMPH. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of NIMPH.

    摘要翻译: 本发明提供了一种新的人内膜蛋白(NIMPH)和识别和编码NIMPH的多核苷酸。 本发明还提供表达载体,宿主细胞,激动剂,抗体和拮抗剂。 本发明还提供了治疗与NIMPH表达相关的疾病的方法。

    Serpin derived from human hypothalmus
    68.
    发明授权
    Serpin derived from human hypothalmus 失效
    Serpin衍生自人类下丘脑

    公开(公告)号:US5929210A

    公开(公告)日:1999-07-27

    申请号:US997040

    申请日:1997-12-23

    CPC分类号: C07K14/8121 A61K38/00

    摘要: The present invention provides nucleotide and amino acid sequences that identify and encode a novel serpin (CAPE) expressed in human hypothalamus. The present invention also provides for antisense molecules to the nucleotide sequences which encode CAPE, expression vectors for the production of purified CAPE, antibodies capable for binding specifically to CAPE, hybridization probes or oligonucleotides for the detection of CAPE-encoding nucleotide sequences, genetically engineered host cells for the expression of Cape, a pharmaceutical composition containing biologically active CAPE, a diagnostic test based on CAPE-encoding nucleic acid molecules, and treatment methods comprising administration of biologically active CAPE.

    摘要翻译: 本发明提供鉴定和编码在人下丘脑中表达的新型serpin(CAPE)的核苷酸和氨基酸序列。 本发明还提供编码CAPE的核苷酸序列的反义分子,用于产生纯化的CAPE的表达载体,能够特异性结合CAPE的抗体,用于检测编码CAPE的核苷酸序列的杂交探针或寡核苷酸的遗传工程宿主 用于表达Cape的细胞,含有生物活性CAPE的药物组合物,基于CAPE编码核酸分子的诊断试验,以及包含施用生物活性CAPE的治疗方法。