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公开(公告)号:US06713060B1
公开(公告)日:2004-03-30
申请号:US09481275
申请日:2000-01-11
申请人: Olga Bandman , Neil C. Corley , Karl J. Guegler , Mariah Baughn
发明人: Olga Bandman , Neil C. Corley , Karl J. Guegler , Mariah Baughn
IPC分类号: A61K39395
CPC分类号: C12N9/1205 , A61K38/00
摘要: The invention provides a human Nek1-related protein kinase (NRPK) and polynucleotides which identify and encode NRPK. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of NRPK.
摘要翻译: 本发明提供了人Nek1相关蛋白激酶(NRPK)和识别和编码NRPK的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了用于诊断,治疗或预防与NRPK表达相关的紊乱的方法。
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公开(公告)号:US5928874A
公开(公告)日:1999-07-27
申请号:US49671
申请日:1998-03-27
申请人: Olga Bandman , Neil C. Corley , Karl J. Guegler , Mariah Baughn
发明人: Olga Bandman , Neil C. Corley , Karl J. Guegler , Mariah Baughn
IPC分类号: C12N15/09 , A61K38/00 , A61K38/45 , A61K45/00 , A61P15/00 , A61P35/00 , A61P37/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/12 , C12N15/54 , C12Q1/68 , C07H21/02 , C12N15/00
CPC分类号: C12N9/1205 , A61K38/00
摘要: The invention provides a human Nek1-related protein kinase (NRPK) and polynucleotides which identify and encode NRPK. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of NRPK.
摘要翻译: 本发明提供了人Nek1相关蛋白激酶(NRPK)和识别和编码NRPK的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了用于诊断,治疗或预防与NRPK表达相关的紊乱的方法。
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公开(公告)号:US06030801A
公开(公告)日:2000-02-29
申请号:US295068
申请日:1999-04-20
申请人: Olga Bandman , Neil C. Corley , Karl J. Guegler , Mariah Baughn
发明人: Olga Bandman , Neil C. Corley , Karl J. Guegler , Mariah Baughn
IPC分类号: C12N15/09 , A61K38/00 , A61K38/45 , A61K45/00 , A61P15/00 , A61P35/00 , A61P37/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/12 , C12N15/54 , C12Q1/68 , C12Q1/48 , C12Q1/00 , G01N33/53
CPC分类号: C12N9/1205 , A61K38/00
摘要: The invention provides a human Nek 1-related protein kinase (NRPK) and polynucleotides which identify and encode NRPK. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of NRPK.
摘要翻译: 本发明提供了人Nek1-相关蛋白激酶(NRPK)和识别和编码NRPK的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了用于诊断,治疗或预防与NRPK表达相关的紊乱的方法。
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公开(公告)号:US06277568B1
公开(公告)日:2001-08-21
申请号:US09058368
申请日:1998-04-09
申请人: Preeti Lal , Jennifer L. Hillman , Karl J. Guegler , Neil C. Corley , Mariah Baughn , Yalda Azimzai
发明人: Preeti Lal , Jennifer L. Hillman , Karl J. Guegler , Neil C. Corley , Mariah Baughn , Yalda Azimzai
IPC分类号: C07H2104
CPC分类号: C12N9/93
摘要: The invention provides human ubiquitin-conjugating enzyme homologs (UCEH) and polynucleotides which identify and encode UCEH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of
摘要翻译: 本发明提供了人泛素缀合酶同源物(UCEH)和识别和编码UCEH的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了用于诊断,治疗或预防与表达相关的疾病的方法
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公开(公告)号:US06589935B1
公开(公告)日:2003-07-08
申请号:US09046572
申请日:1998-03-23
IPC分类号: C12N1500
摘要: The invention provides a human insulin receptor tyrosine kinase substrate (IRS-p53h) and polynucleotides which identify and encode IRS-p53h. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of IRS-p53h.
摘要翻译: 本发明提供了人胰岛素受体酪氨酸激酶底物(IRS-p53h)和鉴定和编码IRS-p53h的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了治疗或预防与IRS-p53h表达相关的疾病的方法。
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公开(公告)号:US6165767A
公开(公告)日:2000-12-26
申请号:US45973
申请日:1998-03-20
申请人: Preeti Lal , Henry Yue , Neil C. Corley , Karl J. Guegler , Mariah Baughn
发明人: Preeti Lal , Henry Yue , Neil C. Corley , Karl J. Guegler , Mariah Baughn
IPC分类号: G01N33/50 , A61K38/00 , A61P15/00 , A61P35/00 , A61P37/02 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/02 , C12Q1/68 , G01N33/566 , C12N9/14
CPC分类号: C07K14/47
摘要: The invention provides human protein phosphatase-related molecules (PPRM) and polynucleotides which identify and encode PPRM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of PPRM.
摘要翻译: 本发明提供了鉴定和编码PPRM的人蛋白磷酸酶相关分子(PPRM)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供了用于诊断,治疗或预防与PPRM表达相关的疾病的方法。
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公开(公告)号:US5994081A
公开(公告)日:1999-11-30
申请号:US067351
申请日:1998-04-27
CPC分类号: C07K14/4741
摘要: The invention provides human keratins (KERT) and polynucleotides which identify and encode KERT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of KERT.
摘要翻译: 本发明提供鉴定和编码KERT的人角蛋白(KERT)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与KERT表达相关的障碍的方法。
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公开(公告)号:US20070092885A1
公开(公告)日:2007-04-26
申请号:US11378616
申请日:2006-03-20
申请人: Henry Yue , Monique Yao , Ameena Gandhi , Mariah Baughn , Anita Swarnakar , Narinder Chawla , Madhusudan Sanjanwala , Michael Thornton , Vicki Elliott , Yan Lu , Kimberly Gietzen , Neil Burford , Li Ding , April Hafalia , Y. Tang , Olga Bandman , Bridget Warren , Cynthia Honchell , Dyung Lu , Kavitha Thangavelu , Sally Lee , Yuming Xu , Junming Yang , Preeti Lal , Bao Tran , Craig Ison , Brendan Duggan , Stephanie Sapperstein
发明人: Henry Yue , Monique Yao , Ameena Gandhi , Mariah Baughn , Anita Swarnakar , Narinder Chawla , Madhusudan Sanjanwala , Michael Thornton , Vicki Elliott , Yan Lu , Kimberly Gietzen , Neil Burford , Li Ding , April Hafalia , Y. Tang , Olga Bandman , Bridget Warren , Cynthia Honchell , Dyung Lu , Kavitha Thangavelu , Sally Lee , Yuming Xu , Junming Yang , Preeti Lal , Bao Tran , Craig Ison , Brendan Duggan , Stephanie Sapperstein
CPC分类号: C12N15/1055 , A61K39/3955 , A61K47/64 , A61K47/643 , A61K2039/505 , C07K14/47 , C07K14/4711 , C07K14/4713 , C07K16/18 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/622 , C07K2317/75 , C07K2317/76 , G01N33/5023
摘要: The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
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公开(公告)号:US20050155089A1
公开(公告)日:2005-07-14
申请号:US10820474
申请日:2004-04-07
申请人: Preeti Lal , Y. Tang , Gina Gorgone , Neil Corley , Karl Guegler , Mariah Baughn , Ingrid Akerblom , Janice Au-Young , Henry Yue , Chandra Patterson , Roopa Reddy , Jennifer Hillman , Olga Bandman
发明人: Preeti Lal , Y. Tang , Gina Gorgone , Neil Corley , Karl Guegler , Mariah Baughn , Ingrid Akerblom , Janice Au-Young , Henry Yue , Chandra Patterson , Roopa Reddy , Jennifer Hillman , Olga Bandman
IPC分类号: G01N33/68 , A61K38/00 , A61K39/395 , A61K45/00 , A61P9/00 , A61P15/00 , A61P25/00 , A61P29/00 , A61P35/00 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/02 , C12P21/08 , C12Q1/68 , A01K67/00 , C07H21/04 , C12N9/64
CPC分类号: G01N33/57419 , A61K38/00 , A61K38/1709 , A61K39/3955 , A61K45/06 , C07K14/47 , C07K16/18 , C07K16/40 , C07K2317/76 , G01N2333/916
摘要: The invention provides human signal peptide-containing proteins (HSPP) and polynucleotides which identify and encode HSPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSPP.
摘要翻译: 本发明提供了人信号肽肽蛋白(HSPP)和识别和编码HSPP的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与HSPP表达相关的障碍的方法。
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公开(公告)号:US20050123990A1
公开(公告)日:2005-06-09
申请号:US11048692
申请日:2005-02-02
申请人: Preeti Lal , Henry Yue , Y. Tang , Olga Bandman , Neil Burford , Yalda Azimzai , Mariah Baughn , Dyung Lu , Chandra Arivzu-Patterson
发明人: Preeti Lal , Henry Yue , Y. Tang , Olga Bandman , Neil Burford , Yalda Azimzai , Mariah Baughn , Dyung Lu , Chandra Arivzu-Patterson
CPC分类号: C07K14/47 , C07K14/705
摘要: The invention provides human membrane associated proteins (MEMAP) and polynucleotides which identify and encode MEMAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of MEMAP.
摘要翻译: 本发明提供了人膜相关蛋白(MEMAP)和识别和编码MEMAP的多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与MEMAP表达相关的疾病的方法。
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