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    Electrode implantation in a pelvic floor muscular structure
    61.
    发明授权
    Electrode implantation in a pelvic floor muscular structure 有权
    电极植入骨盆底肌肉结构

    公开(公告)号：US09539433B1

    公开(公告)日：2017-01-10

    申请号：US12406434

    申请日：2009-03-18

    申请人： Alan G. Wirbisky ,  Andrew P. VanDeWeghe ,  Peter Rehder

    发明人： Alan G. Wirbisky ,  Andrew P. VanDeWeghe ,  Peter Rehder

    IPC分类号： A61N1/00 ,  A61N1/38

    CPC分类号： A61N1/38 ,  A61N1/0512 ,  A61N1/0514 ,  A61N1/36007

    摘要： In a method of implanting an electrode of an electronic stimulator device into a pelvic floor muscular structure of a patient, a stimulation lead having a proximal end and a distal end comprising an electrode is provided. The distal end of the stimulation lead is fed along a path, which is adjacent the pubic symphysis of a patient, toward a pelvic floor muscular structure of the patient. The distal end of the stimulation lead is then fed into the pelvic floor muscular structure of the patient. In one embodiment, the pelvic floor muscular structure comprises the external urinary sphincter of the patient. In accordance with other embodiments, the pelvic floor muscular structure comprises one of the external anal sphincter, the levator ani muscle, the puborectalis sling muscle and prostate tissue.

    摘要翻译： 在将电子刺激器装置的电极植入到患者的盆底肌肉结构中的方法中，提供具有近端和包括电极的远端的刺激引线。 刺激引线的远端沿着与病人的耻骨联合相邻的路径朝向患者的盆底肌肉结构进给。 然后将刺激引线的远端进入患者的盆底肌肉结构。 在一个实施例中，骨盆底肌肉结构包括患者的外部尿道括约肌。 根据其他实施例，骨盆底肌肉结构包括外肛门括约肌，提肌肛肌，耻骨直肠垂体肌和前列腺组织之一。

    APPARATUS AND METHOD FOR ELECTRICALLY ADMINISTERED SEIZURE THERAPY USING TITRATION IN THE CURRENT DOMAIN
    64.
    发明申请
    APPARATUS AND METHOD FOR ELECTRICALLY ADMINISTERED SEIZURE THERAPY USING TITRATION IN THE CURRENT DOMAIN 有权
    用于电流管理的电流治疗方法的装置和方法

    公开(公告)号：US20140236264A1

    公开(公告)日：2014-08-21

    申请号：US14262234

    申请日：2014-04-25

    申请人： MECTA Corporation

    发明人： Harold A. Sackeim

    IPC分类号： A61N1/36 ,  A61N1/372

    CPC分类号： A61N1/36014 ,  A61N1/36025 ,  A61N1/3727 ,  A61N1/38

    摘要： An ECT system capable of focusing the electrical signals on a specific portion of the patient's brain is provided. The ECT system includes a means of applying unidirectional electrical signals and asymmetric electrodes for focusing the signals on the patient. A method of titrating an electro-convulsive therapy (ECT) system and a method of operating an ECT system are also provided. The method includes setting an initial current value, administering an ECT signal to the patient, determining if the seizure threshold has been achieved, and repeating as necessary until the seizure threshold is achieved.

    摘要翻译： 提供了能够将电信号聚焦在患者大脑的特定部分上的ECT系统。 ECT系统包括应用单向电信号和不对称电极的手段，用于将信号聚焦在患者身上。 还提供滴定电惊厥治疗（ECT）系统的方法和操作ECT系统的方法。 该方法包括设置初始电流值，向患者施加ECT信号，确定是否已经实现了惊厥阈值，并根据需要重复，直到达到癫痫发作阈值。

    Method and apparatus for focusing electrical stimulation in the brain during electro-convulsive therapy
    65.
    发明授权
    Method and apparatus for focusing electrical stimulation in the brain during electro-convulsive therapy 有权
    电刺激治疗期间脑电刺激的方法和装置

    公开(公告)号：US08712532B2

    公开(公告)日：2014-04-29

    申请号：US12464545

    申请日：2009-05-12

    申请人： Harold A. Sackeim

    发明人： Harold A. Sackeim

    IPC分类号： A61N1/18

    CPC分类号： A61N1/36014 ,  A61N1/36025 ,  A61N1/3727 ,  A61N1/38

    摘要： An ECT system capable of focusing the electrical signals on a specific portion of the patient's brain is provided. The ECT system includes a means of applying unidirectional electrical signals and asymmetric electrodes for focusing the signals on the patient. A method of titrating an electro-convulsive therapy (ECT) system and a method of operating an ECT system are also provided. The method includes setting an initial current value, administering an ECT signal to the patient, determining if the seizure threshold has been achieved, and repeating as necessary until the seizure threshold is achieved.

    摘要翻译： 提供了能够将电信号聚焦在患者大脑的特定部分上的ECT系统。 ECT系统包括应用单向电信号和不对称电极的手段，用于将信号聚焦在患者身上。 还提供滴定电惊厥治疗（ECT）系统的方法和操作ECT系统的方法。 该方法包括设置初始电流值，向患者施加ECT信号，确定是否已经实现了惊厥阈值，并根据需要重复，直到达到癫痫发作阈值。

    Stimulus dose system and method for electroconvulsive therapy
    68.
    发明申请
    Stimulus dose system and method for electroconvulsive therapy 审中-公开
    电刺激治疗的刺激剂量系统和方法

    公开(公告)号：US20080188905A1

    公开(公告)日：2008-08-07

    申请号：US11670589

    申请日：2007-02-02

    申请人： Conrad M. Swartz

    发明人： Conrad M. Swartz

    IPC分类号： A61N1/36

    CPC分类号： A61N1/36025 ,  A61N1/38

    摘要： A method of treating a patient includes administering an electroconvulsive therapy (ECT) stimulus to the patient. The current is greater than about 0.9 ampere or 1.0 ampere, or is between about 1.0 and about 2 amperes. The energy delivered is about 100 Joules or less across an impedance of 200 ohms. The stimulus may have a pulsewidth between about 0.5 and about 2.0 msec and/or a frequency in the range of about 10 to about 180 Hz, or the stimulus may have a pulsewidth between about 0.2 and about 0.499 msec and/or a frequency in the range of about 15 to about 300 Hz. An apparatus for ECT comprises a generator adapted to deliver such an electroconvulsive therapy stimulus to a patient. A method of calculating ECT dose comprises multiplying a charge to be delivered by the current (or voltage) to an exponential power between 2 and 4.

    摘要翻译： 治疗患者的方法包括向患者施用电惊厥治疗（ECT）刺激。 电流大于约0.9安培或1.0安培，或者介于约1.0和约2安培之间。 在200欧姆的阻抗下，传递的能量约为100焦耳或更少。 刺激可以具有在约0.5和约2.0毫秒之间的脉冲宽度和/或约10至约180Hz范围内的频率，或者刺激可以具有在约0.2和约0.499毫秒之间的脉冲宽度和/或 范围为约15至约300Hz。 用于ECT的装置包括适于将这种电惊厥治疗刺激递送给患者的发生器。 计算ECT剂量的方法包括将由电流（或电压）传递的电荷乘以2和4之间的指数功率。

    Defibrillation shock strength determination technology
    69.
    发明申请
    Defibrillation shock strength determination technology 有权
    除颤冲击强度测定技术

    公开(公告)号：US20030195569A1

    公开(公告)日：2003-10-16

    申请号：US10351143

    申请日：2003-01-27

    发明人： Charles D. Swerdlow ,  Kalyanam Shivkumar

    IPC分类号： A61N001/39

    CPC分类号： A61N1/3943 ,  A61N1/38 ,  A61N1/3987

    摘要： A method for determining a cardiac shock strength, for example the programmed first-therapeutic shock strength of an implantable cardioverter defibrillator (ICD), including the steps of sensing a change in a T-wave of an electrogram with respect to time such as the maximum of the first derivative of a T-wave of an electrogram; delivering a test shock by (i) delivering a test shock at a test-shock strength and at a test-shock time relating to the maximum of the first derivative of the T-wave with respect to time; and (ii) sensing for cardiac fibrillation. If fibrillation is not sensed, test-shock delivery is repeated at the same test-shock strength and at specific, different test-shock times relating to the maximum of the first derivative of the T-wave. If fibrillation is still not sensed, the shock strength is decreased and test shocks are repeated at the same specific test shock times relative to the maximum of the first derivative of the T-wave. And if fibrillation is sensed, the programmed therapeutic shock strength of the ICD is set as a function of the incrementally greater test-shock strength. Also disclosed is an apparatus for selecting a programmed first-shock strength of an ICD, including a shock subsystem for delivering therapeutic shocks and test shocks to the heart, and a ULV subsystem connected to the shock subsystem, to provide test shocks of test-shock strengths and at test-shock times relating to the maximum of the first derivative of the T-wave with respect to time, and to determine the therapeutic shock strength of the ICD as a function of the test-shock strengths.

    摘要翻译： 一种用于确定心脏休克强度的方法，例如可植入式心脏复律除颤器（ICD）的编程的第一治疗性休克强度，包括以下步骤：相对于诸如最大值的时间感测电描记图的T波的变化 的电摄影的T波的一阶导数; 通过（i）以测试冲击强度和与T波一阶导数的最大值相对于时间的测试冲击时间提供测试冲击，从而发生测试冲击; 和（ii）感觉心脏颤动。 如果未检测到原纤维颤动，则以相同的测试冲击强度和与T波一阶导数的最大值相关的特定的不同测试冲击时间重复测试冲击输送。 如果仍然没有检测到原纤维化，则相对于T波的一阶导数的最大值，冲击强度降低，并且在相同的特定测试冲击时间重复测试冲击。 并且如果感觉到颤动，ICD的编程治疗性休克强度被设定为逐渐增大的测试冲击强度的函数。 还公开了一种用于选择ICD的编程的第一冲击强度的装置，包括用于递送治疗性冲击并测试心脏震动的冲击子系统，以及连接到冲击子系统的ULV子系统，以提供测试冲击的测试冲击 强度和与T波的一阶导数相对于时间的最大值的测试冲击时间，并且确定作为测试冲击强度的函数的ICD的治疗性冲击强度。

    Method and apparatus for a cardiac defibrillator high voltage charging circuit
    70.
    发明授权
    Method and apparatus for a cardiac defibrillator high voltage charging circuit 失效
    心脏除颤器高压充电电路的方法和装置

    公开(公告)号：US5285779A

    公开(公告)日：1994-02-15

    申请号：US858808

    申请日：1992-03-27

    申请人： David B. Cameron ,  Paul D. Bliley

    发明人： David B. Cameron ,  Paul D. Bliley

    IPC分类号： A61N1/08 ,  A61N1/38 ,  A61N1/39 ,  A61N1/00

    CPC分类号： A61N1/38 ,  A61N1/08 ,  A61N1/3925 ,  A61N1/3981

    摘要： A variable rate defibrillator charging circuit includes a power transformer that accepts an internal battery output and the output from an AC-to-DC converter on separate primary windings. The secondary winding of the transformer is coupled through a rectifier to a storage capacitor. The transformer operates in a fly-back mode whereby energy is discharged into the storage capacitor when the power supplies discontinue charging the transformer. After energy in the transformer is discharged into the storage capacitor, the power supplies are reactivated, recharging the transformer. The separate primary windings of the transformer provide a fast, reliable, low cost means for charging the storage capacitor with multiple power supplies. The AC power source feeding the AC-to-DC converter is detachable allowing the defibrillator to be operated remotely whereby the storage capacitor is charged solely from the internal battery. The charging circuit monitors the output voltage levels of both the battery and the AC-to-DC converter and enables or disables the power supplies in accordance to their ability to charge the storage capacitor within a predetermined amount of time. The energy in the storage capacitor, which is eventually discharged into a patient, is monitored to prevent overcharging.

    摘要翻译： 可变速率除颤器充电电路包括接收内部电池输出的电力变压器和在单独的初级绕组上的来自AC-DC转换器的输出。 变压器的次级绕组通过整流器耦合到存储电容器。 变压器以回扫模式工作，当电源中断对变压器充电时，能量被放入存储电容器中。 变压器内的能量被放入储存电容器后，电源被重新激活，对变压器进行充电。 变压器的单独的初级绕组提供了一种快速，可靠，低成本的方法，用于对具有多个电源的存储电容器进行充电。 馈电AC-DC转换器的AC电源是可拆卸的，允许除颤器远程操作，从而存储电容器仅从内部电池充电。 充电电路监视电池和AC-DC转换器的输出电压电平，并根据其在预定时间内对存储电容器充电的能力启用或禁用电源。 监测储存电容器中最终排放到患者体内的能量，以防止过度充电。