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公开(公告)号：US20020151423A1
公开(公告)日：2002-10-17
申请号：US10174188
申请日：2002-06-18
IPC分类号： B04B005/02
CPC分类号： A61M1/3693 , A61M1/0209 , A61M1/029 , A61M1/3698 , A61M2202/0427 , B04B5/0428 , B04B2005/0435 , Y10S383/904
摘要： A single use system and kit for producing blood platelet concentrates is described herein. In a preferred form, the kit includes a bag set in which compartments containing blood components are adjacent to separate compartments which can be inflated to express the blood components after their separation by centrifuging.
摘要翻译： 本文描述了用于生产血小板浓缩物的单次使用系统和试剂盒。 在优选形式中，试剂盒包括袋组，其中含有血液成分的隔室与独立的隔间相邻，隔室可以在通过离心分离后被充气以表达血液成分。
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公开(公告)号：US6019716A
公开(公告)日：2000-02-01
申请号：US114616
申请日：1998-07-13
CPC分类号： B04B5/0428 , A61M1/029 , A61M1/3693 , B04B2005/0435
摘要： A device is provided for use in a centrifuge to separate or isolate material (such as pelleted cells, particulates, aggregates, compounds, blood components, and the like) from the liquid in which they are suspended while limiting or preventing loss of any of the resulting separated or pelleted material during further manipulations. The device can be inserted into a standard centrifugation bucket in a centrifuge and holds a flexible centrifuge bag. The device includes at least one damp assembly, which includes a partition that is maintained in an open position during centrifugation and in a closed position at unit gravity, thus isolating separated or pelleted material at the bottom of the flexible bag in the device after centrifugation and preventing the isolated material from being disturbed during liquid changes and other manipulations. The invention also encompasses a method for isolating material in a centrifuge bag following centrifugation utilizing the flexible bag-holding device described herein, as well as a flexible bag to be used with the device.
摘要翻译： 提供一种用于离心机中的装置，用于分离或分离其悬浮液体中的材料（例如颗粒细胞，颗粒，聚集体，化合物，血液成分等），同时限制或防止任何 在进一步操作期间产生分离或沉淀的材料。 该装置可以插入离心机中的标准离心桶中，并保持柔性离心机袋。 该装置包括至少一个潮湿组件，其包括在离心期间保持在打开位置并且在单位重力下处于关闭位置的分隔件，从而在离心后在装置中的柔性袋的底部隔离分离或沉淀的材料，以及 防止隔离材料在液体变化和其他操作过程中受到干扰。 本发明还包括在利用本文所述的柔性袋保持装置进行离心之后在离心机袋中隔离材料的方法以及与该装置一起使用的柔性袋。
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公开(公告)号：US5935052A
公开(公告)日：1999-08-10
申请号：US68498
申请日：1993-05-27
CPC分类号： B04B5/0414 , B04B2005/0435
摘要： An adapter for use in a fixed angle centrifuge rotor has, in use, a radially inboard and a radially inboard portion. An opening is formed in the radially inboard portion of the adapter. The opening is sized so that substantially no part of the inboard portion of the adapter is exposed during centrifugation to a load that exceeds the ability of the material of the adapter to support itself. The material of the inboard portion of the adapter surrounding the opening has sufficient strength to support itself while under centrifugation. The adapter is fabricated from a light transmissive material. A plug that is slidably disposed and selectably positionable within the opening in the inboard segment of the adapter. The inside surface of the plug having a sealing material thereon that is biased into contact with a tube carried within the adapter.
摘要翻译： 用于固定角度离心机转子的适配器在使用中具有径向内侧和径向内侧部分。 开口形成在适配器的径向内侧部分中。 开口的尺寸使得在离心过程中基本上没有适配器的内侧部分的一部分暴露于超过适配器的材料支撑其自身能力的负载。 围绕开口的适配器的内侧部分的材料具有足够的强度以在离心时自身支撑。 适配器由透光材料制成。 可滑动地设置并可选择地定位在适配器的内侧段中的开口内的插头。 插塞的内表面上具有密封材料，该密封材料偏置成与适配器内承载的管接触。
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公开(公告)号：US5399144A
公开(公告)日：1995-03-21
申请号：US140057
申请日：1993-11-04
CPC分类号： B04B5/0414 , B04B2005/0435
摘要： A centrifuge tube adapter for supporting a closed tube in a cavity of a vertical angle centrifuge rotor includes an inboard and an outboard adapter segment. A hinge connects the segments and supports relative pivotal movement of one segment with respect to the other. The hinge comprises a pair of axles formed at the lower end of one segment and a pair of trunnions formed at a corresponding location on the other segment. The inboard segment has a flange and the outboard segment has a channel therein sized to receive the flange. The flange has serrations thereon.
摘要翻译： PCT No.PCT / US92 / 03813 Sec。 371日期：1993年11月4日 102（e）日期1993年11月4日PCT提交1992年5月6日PCT公布。 WO92 / 19382 PCT出版物 日期：1992年11月12日。用于支撑垂直角度离心机转子的空腔中的封闭管的离心管适配器包括内侧和外侧适配器段。 铰链连接部分并且支撑一个部分相对于另一个部分的相对枢转运动。 铰链包括形成在一个段的下端的一对轴和形成在另一个段上相应位置的一对耳轴。 内侧段具有凸缘，并且外侧段具有其中具有容纳凸缘的尺寸的通道。 凸缘上有锯齿。
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公开(公告)号：US4990129A
公开(公告)日：1991-02-05
申请号：US232813
申请日：1988-08-16
申请人： Steven T. Nielsen
发明人： Steven T. Nielsen
IPC分类号： B04B5/04
CPC分类号： B04B5/0414 , B04B2005/0435
摘要： An adapter preferably of ultra high molecular weight polyethylene is provided for use with a conical centrifuge tube in an ultracentrifuge swinging bucket rotor hole and is designed to allow the easy removal of the adapter and tube after centrifugation. At the top of the adapter is an integral annular rim with an outside diameter equal to that of a cylindrical upper portion of the centrifuge tube and with a minimal clearance to the diameter of the rotor hole. Immediately below the annular rim and adapter diameter reduces to a lesser diameter and continues until intersection with a hemispherical bottom region. The internal configuration of the adapter has a tapered conical section ending in a reduced diameter hemisphere, the internal taper and hemisphere of the adapter exactly matching the exterior of supported conical portion and hemispherical termination end of the sample tube.
摘要翻译： 优选使用超高分子量聚乙烯的适配器用于超离心机摆动式桶式转子孔中的锥形离心管，并且设计成允许在离心后容易地去除接头和管。 在适配器的顶部是整体的环形边缘，其外径等于离心管的圆柱形上部的外径，并且与转子孔的直径具有最小的间隙。 刚好在环形边缘的下方和适配器直径减小到更小的直径，并继续直到与半球形底部区域相交。 适配器的内部结构具有终止于直径减小的半球的锥形锥形部分，适配器的内部锥形和半球与支撑圆锥形部分的外部和样品管的半球状终止端完全匹配。
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公开(公告)号：US4692137A
公开(公告)日：1987-09-08
申请号：US719179
申请日：1985-04-03
申请人： Linda J. Anthony
发明人： Linda J. Anthony
CPC分类号： B04B5/0414 , B04B2005/0435
摘要： A centrifuge adapter is formed in two sections divided by a plane that preferably extends through the longitudinal axis of the adapter. The two sections may be substantially identical in a first embodiment, each including a generally semicylindrical portion having a trough therein and further including an end portion. In a second embodiment, the adapter may comprise a first section including the entire bottom end portion for supporting the bottom of a centrifuge tube. The second section is formed generally as a semicylinder. When the first and second portions are assembled in facing relationship the troughs form a cavity for receiving a centrifuge tube therein. The sections of the adapter may be separate pieces, or they may hingedly connected along a pair of adajcent edges. The sections may be connected by projections extending from one section into corresponding cavities in the other section. The sections are easily separated after the sample has been centrifuged to remove the centrifuge sample tube from the adapter.
摘要翻译： 离心机适配器形成在两个部分中，该平面分隔成优选地延伸穿过适配器的纵向轴线的平面。 两个部分可以在第一实施例中基本相同，每个部分包括在其中具有槽的大致半圆柱形部分并且还包括端部。 在第二实施例中，适配器可以包括第一部分，其包括用于支撑离心管底部的整个底端部分。 第二部分通常形成为半圆形。 当第一和第二部分以面对关系组装时，槽形成用于在其中接收离心管的空腔。 适配器的部分可以是分开的部件，或者它们可以沿着一对相邻边缘铰接连接。 这些部分可以通过在另一部分中从一个部分延伸到相应的空腔中的突起连接。 在离心样品以从适配器中取出离心机样品管后，这些部分容易分离。
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公开(公告)号：US3674197A
公开(公告)日：1972-07-04
申请号：US3674197D
申请日：1970-09-08
申请人： SORVALL INC IVAN
CPC分类号： B04B5/0442 , B04B5/0428 , B04B2005/0435
摘要： Improved enclosure for supporting flexible bags within a centrifuge rotor for washing biological particles in a closed system. Each collapsible bag is enclosed and supported by a juxtaposed pair of half-shells forming a unitary cavity or chamber to which the filled bag conforms during centrifugation. The enclosure serves to prevent undue wear and stress upon the rotor receptacle and, at the same time, safeguards the integrity of the flexible bag during centrifugation.
摘要翻译： 改进的外壳，用于在离心机转子内支撑柔性袋，用于在封闭系统中清洗生物颗粒。 每个可折叠的袋子由并排的一对半壳体包围并支撑，形成在离心过程中填充的袋子符合的整体空腔或室。 外壳用于防止转子接收器上的不适当的磨损和应力，同时在离心过程中保护柔性袋的完整性。
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公开(公告)号：US20180272361A1
公开(公告)日：2018-09-27
申请号：US15764300
申请日：2016-07-20
发明人： Hideki YOSHIDA
CPC分类号： B04B5/0414 , B01L9/06 , B01L2200/087 , B01L2300/0851 , B04B5/0421 , B04B2005/0435
摘要： There can be provided a tube rack of a centrifugal separator, in which a bottom rubber portion can be readily mounted and readily replaced, and yet such bottom rubber portion cannot be easily separated. The tube rack includes a holder (14) including a plurality of tube holes (12) each configured to accommodate a tube that is used for a sample and each includes an opening at one end portion of the holder serving as a tube insertion side, and an opening at a bottom portion of the holder that is at the other end. The tube rack includes a bottom rubber portion (15) including a plurality of bottom rubber members (25) each fits in the tube hole (12), and including connecting pieces (24). The tube rack includes a base (13) formed in a cylindrical shape having a bottom configured to accommodate and detachably hold the holder (14) and the bottom rubber portion (15), and to be inserted into a bucket of the centrifugal separator.
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公开(公告)号：US20180085760A1
公开(公告)日：2018-03-29
申请号：US15558623
申请日：2016-03-17
发明人： Tadashi Imai
CPC分类号： B04B5/02 , A61M1/025 , A61M1/0272 , A61M1/3693 , B04B5/0421 , B04B5/0428 , B04B2005/0435
摘要： A centrifuge (70) is provided with a cup (80) configured to house a blood bag system (10a) and centrifugally separates blood in the blood bag system (10a) by rotating the cup (80). The cup (80) has a segment holding section (86) capable of holding a plurality of segment tubes (44a), aligned in a parallel state by being folded at a sealing portion (44b) of an outlet-side tube (44), along a direction in which a centrifugal force acts during centrifugal processing or a direction inclined with respect to the direction in which the centrifugal force acts.
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公开(公告)号：US09849453B2
公开(公告)日：2017-12-26
申请号：US14295689
申请日：2014-06-04
申请人： QIAGEN GmbH
CPC分类号： B01L3/5021 , B01L3/50255 , B01L3/56 , B01L9/06 , B01L2200/023 , B01L2400/0409 , B04B5/02 , B04B5/0421 , B04B2005/0435 , G01N1/405 , G01N1/4077 , G01N2035/00485 , G01N2035/00504 , Y10T436/25375
摘要： The present invention relates to improved methods for processing fluids and to a fluid processing device (1) for use in a centrifuge comprising: (a) a first holder (14) form-fit to the shape of a first tube (18) for holding said first tube (18) whereby said first tube (18) has a first cross section (A1); and (b) a second holder (22) form-fit to the shape of a second tube (26) for holding said second tube (26) whereby said second tube (26) has a second cross section (A2) that is different from said first cross section (A1). With the fluid processing devices and the methods according to the invention, it is possible to simplify the centrifugal processing steps for a given fluid processing sequence and to automate them.
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