摘要:
This invention concerns a process for killing internal parasites, especially nematodes and cestodes affecting warm blooded animals such as sheep, cattle, swine, goats, dogs, cats, horses and humans as well as poultry by administering an effective amount of a compound of the Formula I: ##STR1## Certain of the compounds of Formula I are novel and in further embodiments of the invention provide novel compounds and compositions for use in the process of the invention. The compounds are readily prepared by conventional chemical reactions. Various pyridinyl acylhydrazones of Formula I demonstrate broad-spectrum anthelmintic activity in sheep upon oral and/or parenteral administration.
摘要:
As new compound is provided a cyclohexane derivative of the formula ##STR1## wherein R.sup.1 is a hydrogen or a lower alkyl; R.sup.2 is a lower alkyl; R.sup.3 is a hydrogen, an alkyl, an alkenyl, a hydroxyalkyl, a cycloalkyl, a morpholino, an aminoalkyl, an N-alkylaminoalkyl, an N,N-di-alkylaminoalkyl, an alkoxycarbonylalkyl, a group of the formula --(CH.sub.2).sub.l --R.sup.4 where R.sup.4 is a lower alkoxy, a lower alkylthio, a benzylthio, an anilino, a morpholino, a piperazino, a piperidino or a lower alkyl-substituted piperidino and l is 2 or 3, a group of the formula ##STR2## where X is a halogen, a lower alkyl, a lower alkoxy, a phenoxy or an alkoxycarbonylalkyloxy, m is zero or 1 and n is an integer of zero to 2, inclusive, a group of the formula --CH.sub.2 --R.sup.5 where R.sup.5 is a furyl, a thenyl or a pyridyl, or a group of the formula ##STR3## where R.sup.5 is as defined above; or a salt of said cyclohexane derivative.This cyclohexane derivative exhibits useful plant growth regulating effects on crop-plants and also non-crop-plant such as lawn.
摘要:
A process for condensing a carboxylic acid with ammonia, hydrazine or a substituted hydrazine or a primary or secondary amine to give a compound containing the group --CO--NR'-- where R' is a hydrogen atom, an organic radical, an NH.sub.2 group or a substituted NH.sub.2 group by the use of a catalyst having a formula M(OR).sub.n X.sub.(4.sub.-n) wherein M represents titanium or zirconium, R represents an alkyl or aryl radical, X represents a halogen atom and n is an integer from 1 to 4.
摘要:
THIS INVENTION RELATES TO NOVEL HETEROCYCLIC ACID CHLORIDE PHENYLHYDRAZONES EMBRACED BY THE FORMULA
(R-CCL=N-NH-),(CL)N-BENZENE
WHEREIN R IS A RADICAL SELECTED FROM THE GROUP CONSISTING OF FURYL, THIENYL AND PYRIDYL, EACH OF WHICH HAS FROM ZERO THROUGH THREE SUBSTUENTS SELECTED FROM THE GROUP CONSISTING OF ALKYL, HALO AND NITRO, AND N IS AN INTEGER OF FROM ZERO THROUGH THREE. THESE COMPOUNDS ARE PRIMARILY USEFUL AS INSECTICIDES AND MITICIDES AND ALSO AS HERBICIDES, ANTIINFLAMMATORIES AND ANTHELMINTICS.
摘要:
This invention relates to agents that are inhibitors or activators of variant forms of endogenous proteins and novel methods of identifying such variants. Of particular interest are inhibitors and activators of endogenous protein variants, encoded by genes which have mutated, which variants often arise or are at least first identified as having arisen following exposure to a chemical agent which is known to be an inhibitor or activator of the corresponding unmutated endogenous protein.