Anthelmintic pyridinyl acylhydrazones
    61.
    发明授权
    Anthelmintic pyridinyl acylhydrazones 失效
    驱虫剂吡啶基酰腙

    公开(公告)号:US5023334A

    公开(公告)日:1991-06-11

    申请号:US402385

    申请日:1989-09-01

    摘要: This invention concerns a process for killing internal parasites, especially nematodes and cestodes affecting warm blooded animals such as sheep, cattle, swine, goats, dogs, cats, horses and humans as well as poultry by administering an effective amount of a compound of the Formula I: ##STR1## Certain of the compounds of Formula I are novel and in further embodiments of the invention provide novel compounds and compositions for use in the process of the invention. The compounds are readily prepared by conventional chemical reactions. Various pyridinyl acylhydrazones of Formula I demonstrate broad-spectrum anthelmintic activity in sheep upon oral and/or parenteral administration.

    摘要翻译: 本发明涉及通过施用有效量的式(I)化合物来杀死内部寄生虫,特别是影响温血动物例如绵羊,牛,猪,山羊,狗,猫,马和人以及家禽的内部寄生虫, I:图像I某些式I的化合物是新的,并且在本发明的另外的实施方案中提供了用于本发明方法的新型化合物和组合物。 通过常规化学反应容易地制备化合物。 式I的各种吡啶基酰腙在口服和/或肠胃外给药时显示出绵羊的广谱驱虫活性。

    Process for making nicotinic acid hydrazides
    65.
    发明授权
    Process for making nicotinic acid hydrazides 失效
    制造烟酸酰肼的方法

    公开(公告)号:US3951996A

    公开(公告)日:1976-04-20

    申请号:US426669

    申请日:1973-12-12

    摘要: A process for condensing a carboxylic acid with ammonia, hydrazine or a substituted hydrazine or a primary or secondary amine to give a compound containing the group --CO--NR'-- where R' is a hydrogen atom, an organic radical, an NH.sub.2 group or a substituted NH.sub.2 group by the use of a catalyst having a formula M(OR).sub.n X.sub.(4.sub.-n) wherein M represents titanium or zirconium, R represents an alkyl or aryl radical, X represents a halogen atom and n is an integer from 1 to 4.

    摘要翻译: 将羧酸与氨,肼或取代的肼或伯或仲胺缩合以得到含有-CO-NR'-基团的化合物的方法,其中R'为氢原子,有机基团,NH 2基团或 通过使用具有式M(OR)n X(4-n)的催化剂的取代的NH 2基团,其中M表示钛或锆,R表示烷基或芳基,X表示卤素原子,n表示1的整数 到4。

    Halogen substituted pyrininealdehyde phenyl hydrazones
    66.
    发明授权
    Halogen substituted pyrininealdehyde phenyl hydrazones 失效
    卤素取代的吡啶基苯并噻吩

    公开(公告)号:US3699111A

    公开(公告)日:1972-10-17

    申请号:US3699111D

    申请日:1970-10-05

    申请人: UPJOHN CO

    发明人: KAUGARS GIRTS

    CPC分类号: C07D213/87 C07D333/38

    摘要: THIS INVENTION RELATES TO NOVEL HETEROCYCLIC ACID CHLORIDE PHENYLHYDRAZONES EMBRACED BY THE FORMULA

    (R-CCL=N-NH-),(CL)N-BENZENE

    WHEREIN R IS A RADICAL SELECTED FROM THE GROUP CONSISTING OF FURYL, THIENYL AND PYRIDYL, EACH OF WHICH HAS FROM ZERO THROUGH THREE SUBSTUENTS SELECTED FROM THE GROUP CONSISTING OF ALKYL, HALO AND NITRO, AND N IS AN INTEGER OF FROM ZERO THROUGH THREE. THESE COMPOUNDS ARE PRIMARILY USEFUL AS INSECTICIDES AND MITICIDES AND ALSO AS HERBICIDES, ANTIINFLAMMATORIES AND ANTHELMINTICS.