Abstract:
A method to detect a phase separation of gasoline and ethanol may include the steps of generating a sound signal in a tank, determining a speed of the sound signal, determining an interface level in the tank, determining the speed of the sound signal below the interface level and determining the phase separation based upon the speed of the sound signal.
Abstract:
Chiral 1-(4-methylphenylmethyl)-5-oxo-{N-[(3-t-butoxycarbonyl-aminomethyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamides as inhibitors of collagen induced platelet activation and adhesion The present invention provides chiral (2S)-1-(4-methyl-phenylmethyl)-5-oxo-(3S)-{N-[(3-t butoxycarbonyl aminomethyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamide, and (2S)-1-(4-methylphenylmethyl)-5-oxo-(3R)-{N-[(3-t-butoxycarbonyl amino methyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamide of formula 6 and 7 respectively. The present invention also relates to use of these moieties as inhibitors of collagen induced platelet adhesion and aggregation mediated through collagen receptors. The present invention provides a process for preparation of chiral carboxamides of formula 6 and 7 using the process which has advantage to avoid any racemization at the a-carboxylic center, during N-alkylation. The reagent LiHMDS is used at low temperatures to furnish methyl N-(p methylphenylmethyl)lpyroglutamate in good chiral purity.
Abstract:
The present invention relates to a process for improving pegylation reaction yield of r-metHuG-CSF comprising conjugating r-metHuG-CSF to a PEG aldehyde at a free amine moiety at the N terminal end on the G-CSF in presence of a reducing agent in a pegylation buffer solution comprising a polyol having the formula CnH2n+2On where n is from 3 to 6, or a carbohydrate, or a derivative thereof wherein the concentration of said polyol or carbohydrate or derivative thereof is in the range of 0.1% to 10% w/w.
Abstract translation:本发明涉及一种改善r-metHuG-CSF的聚乙二醇化反应产率的方法,其包括将r-metHuG-CSF与G-CSF上N-末端的游离胺部分的PEG醛在还原剂 在包含式C n H 2n + 20n的多元醇(其中n为3至6)的聚乙二醇化缓冲溶液中,或其中所述多元醇或碳水化合物或其衍生物的浓度在0.1至10的范围内的碳水化合物或其衍生物 %w / w。
Abstract:
A method for dynamically computing an equi-distance point (EDP) for an aircraft includes receiving at least two reference points for landing the aircraft upon an occurrence of an emergency, determining a remaining flight path for the aircraft based on a current location of the aircraft and a flight plan serviced by a flight management system (FMS) of the aircraft, and generating the EDP for the aircraft by locating a point on the remaining flight path which is equidistant from the at least two reference points.
Abstract:
A nonvolatile floating gate analog memory cell (1) comprising a transistor having a source (2) and drain (3) formed inside a substrate or on an insulator body (not shown) and separated by a channel (4). The memory cell comprises at least one floating gate (5) formed on one side of the source and drain. (6) is a control gate formed on one side of the floating gate and connected to a first voltage (7). (8) is a back gate formed on the other side of the source and drain and connected to a second voltage (9). The channel is separated from the floating gate and the back gate by an insulation layer (10). The control gate is separated from the floating gate by an insulation layer (11) and the source and drain are isolated from the back gate, control gate and floating gate(s) by a spacer (12). The second voltage changes the intrinsic threshold voltage linearly during programming so that the programmed threshold voltage corresponds to the second voltage.
Abstract:
A method for replicating a program and data storage according to one embodiment comprises sending program replication data from a first program to a second program, the second program having an application program that is a replica of an application program of the first program; sending data storage requests from the first program to a first storage system; and replicating data stored in the first storage system in a second storage system. Additional methods, systems, and computer program products are disclosed.
Abstract:
Example methods and apparatus to poll in wireless communications based on assignments are disclosed. A disclosed example method involves receiving a poll from a network during a first radio block period and identifying a resource for use in sending requested information to the network in response to the poll. The resource occurs during a subsequent radio block period, and the subsequent radio block period is separated from the first radio block period by at least one radio block period not assigned to the mobile station for transmission by the mobile station. The example method also involves transmitting a response to the poll.
Abstract:
Example methods and apparatus to communicate data between a wireless network and a mobile station are disclosed. A disclosed example method involves identifying a first quantity of resources for use in communicating first data to a mobile station in a first radio block period and a second quantity of resources for use in communicating second data to the mobile station in a second radio block period. The total quantity of the first and second quantities of resources comply with a maximum allowable quantity of resources specified for a plurality of radio block periods including the first and second radio block periods. The example method also involves sending, to the mobile station, the first data in the first quantity of resources during the first radio block period and the second data in the second quantity of resources during the second radio block period.
Abstract:
A slew rate improved operational amplifier circuit is provided to improve the slew rates of an operational amplifier with minimal sacrifices in power dissipation and other operational amplifier parameters. To improve the slew rates of operational amplifiers, additional current sources are activated when a slewing operation is detected. The detection of slewing operations and the activation of current sources upon detection can be implemented using two comparator circuits—one for a positive slewing operation, and one for a negative slewing operation. A sub-45 nm FinFET implementation of this slew rate improvement concept was implemented and compared against slew rate optimized individual two-stage operational amplifiers. Simulations show that slew rates were significantly improved by the implementation of the comparator circuits (5590 V/μs vs. 273 V/μs), with minimal increases in power dissipation (78 μW vs. 46 μW).
Abstract translation:提供了一种转换速率改进的运算放大器电路,以便以最小的功耗牺牲和其他运算放大器参数来提高运算放大器的转换速率。 为了提高运算放大器的转换速率,当检测到回转操作时,会激活额外的电流源。 检测到的回转操作和电流源的检测可以使用两个比较器电路实现,一个用于正回转操作,另一个用于负回转操作。 实现了这种转换速率改进概念的45纳米FinFET实现,并将其与转换速率优化的单个两级运算放大器进行比较。 模拟显示,通过实施比较器电路(5590 V /μsvs. 273 V /μs),转换速率得到显着提高,功耗增加最小(78μW至46μW)。
Abstract:
A method for monitoring a structural health of a wind turbine. The method includes transmitting, from a sensor to a controller, at least one monitoring signal indicative of a structural discontinuity, the sensor operatively coupled to a structural component of the wind turbine. A first notification signal is transmitted from the controller to a user computing device upon receiving the monitoring signal.