公开(公告)号：US20100152604A1

公开(公告)日：2010-06-17

申请号：US12711937

申请日：2010-02-24

Applicant: Norbert F. Kaula ,  Jeffrey J. Blewett ,  Goretti Medeiros ,  James Gharib ,  Allen Farquhar

Inventor： Norbert F. Kaula ,  Jeffrey J. Blewett ,  Goretti Medeiros ,  James Gharib ,  Allen Farquhar

IPC: A61B5/0488

CPC classification number: A61B5/4893 ,  A61B5/04001 ,  A61B5/0488 ,  A61B5/1106 ,  A61B5/4836 ,  A61B5/7217 ,  A61B5/743 ,  A61B17/00 ,  A61B17/02 ,  A61B2017/00039 ,  A61N1/08 ,  A61N1/36 ,  A61N1/36017

Abstract: The present invention involves systems and methods for determining nerve proximity, nerve direction, and pathology relative to a surgical instrument based on an identified relationship between neuromuscular responses and the stimulation signal that caused the neuromuscular responses.

Abstract translation: 本发明涉及用于基于神经肌肉反应和引起神经肌肉反应的刺激信号之间确定的关系来确定相对于外科器械的神经接近度，神经方向和病理学的系统和方法。

公开(公告)号：US20100010367A1

公开(公告)日：2010-01-14

申请号：US11794650

申请日：2005-12-30

Applicant: Kevin T. Foley ,  Bret A. Ferree ,  James Gharib

Inventor： Kevin T. Foley ,  Bret A. Ferree ,  James Gharib

IPC: A61B5/0488

CPC classification number: A61B5/6826 ,  A61B5/0488 ,  A61B5/0492 ,  A61B5/4041 ,  A61B5/6838

Abstract: The present invention involves a system and methods for nerve testing during anterior surgery, including but not limited to anterior disc replacement surgery, nucleus replacement, and interbody fusion.

Abstract translation: 本发明涉及前方手术中神经测试的系统和方法，包括但不限于前椎间盘置换手术，细胞核替换和椎体间融合。

公开(公告)号：US20090259108A1

公开(公告)日：2009-10-15

申请号：US12428081

申请日：2009-04-22

Applicant: Patrick Miles ,  Scot Martinelli ,  Eric Finley ,  James Gharib ,  Allen Farquhar ,  Norbert Kaula ,  Jeffrey Blewett ,  Goretti Medeiros

Inventor： Patrick Miles ,  Scot Martinelli ,  Eric Finley ,  James Gharib ,  Allen Farquhar ,  Norbert Kaula ,  Jeffrey Blewett ,  Goretti Medeiros

IPC: A61B1/32 ,  A61M29/00

CPC classification number: A61B17/02 ,  A61B1/32 ,  A61B5/0492 ,  A61B5/4893 ,  A61B5/7405 ,  A61B5/742 ,  A61B17/0206 ,  A61B17/0218 ,  A61B17/025 ,  A61B17/0293 ,  A61B2017/00026 ,  A61B2017/00039 ,  A61B2017/0256 ,  A61B2017/0262

Abstract: A system for accessing a surgical target site and related methods, involving an initial distraction system for creating an initial distraction corridor, and an assembly capable of distracting from the initial distraction corridor to a secondary distraction corridor and thereafter sequentially receiving a plurality of retractor blades for retracting from the secondary distraction corridor to thereby create an operative corridor to the surgical target site, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.

Abstract translation: 用于接近外科手术目标部位的系统和相关方法，涉及用于产生初始牵引走廊的初始牵引系统，以及能够将初始牵引走廊分散到次级牵引走廊的组件，并且随后顺序地接收多个牵开器叶片，用于 从第二分离走廊收回，从而为外科手术目标部位创建一个手术走廊，两者都可配备一个或多个电极，用于检测神经结构的存在（以及可能的距离和/或方向），之前 在建立手术目标地点的手术走廊期间和之后。

公开(公告)号：US20090177112A1

公开(公告)日：2009-07-09

申请号：US11883709

申请日：2006-02-02

Applicant: James Gharib ,  Allen Farquhar ,  Doug Layman ,  Jeff Balzer ,  Blair Calancie

Inventor： James Gharib ,  Allen Farquhar ,  Doug Layman ,  Jeff Balzer ,  Blair Calancie

IPC: A61B5/05

CPC classification number: A61B5/0488 ,  A61B5/4041 ,  A61B5/407 ,  A61B5/4504 ,  A61B5/4893 ,  A61B5/7475 ,  A61N1/0548 ,  A61N1/36003 ,  A61N1/36014 ,  A61N1/37247

Abstract: The present invention relates generally to an algorithm aimed at neurophysiology monitoring, and more particularly to an algorithm capable of quickly finding stimulation thresholds over multiple channels of a neurophysiology monitoring system.

Abstract translation: 本发明一般涉及一种旨在进行神经生理学监测的算法，更具体地说，涉及一种能够在神经生理学监测系统的多个通道上快速找到刺激阈值的算法。

公开(公告)号：US20080221473A1

公开(公告)日：2008-09-11

申请号：US11994411

申请日：2006-09-22

Applicant: Blair Calancie ,  James Gharib ,  Allen Farquhar ,  Doug Layman

Inventor： Blair Calancie ,  James Gharib ,  Allen Farquhar ,  Doug Layman

IPC: A61B5/04 ,  A61F7/12 ,  A61N1/00

CPC classification number: A61B5/0488 ,  A61B5/4041 ,  A61B5/407 ,  A61B5/4893 ,  A61N1/36003 ,  A61N1/36014 ,  A61N1/37247

Abstract: The present invention includes a system and methods aimed at surgery, and more particularly to a system and methods for monitoring nervous tissue to assess the integrity of a pedicle wall during or after pilot hole formation and before, during, or after screw implantation, particularly in the thoracic spine. The system also performs other neurophysiologic assessments including, but not necessarily limited to, neuromuscular pathway status, nerve proximity detection, nerve pathology monitoring, and spinal cord health monitoring.

Abstract translation: 本发明包括一种旨在手术的系统和方法，更具体地说，涉及用于监测神经组织的系统和方法，以在螺钉植入之前，之中或之后评估椎弓根壁的完整性，特别是在 胸椎。 该系统还执行其他神经生理学评估，包括但不一定限于神经肌肉通路状态，神经接近检测，神经病理学监测和脊髓健康监测。

公开(公告)号：US20050075578A1

公开(公告)日：2005-04-07

申请号：US10809280

申请日：2004-03-25

Applicant: James Gharib ,  Allen Farquhar ,  Norbert Kaula ,  Jeffrey Blewett ,  Goretti Medeiros ,  Eric Finley ,  Jamil Elbanna ,  Scot Martinelli

Inventor： James Gharib ,  Allen Farquhar ,  Norbert Kaula ,  Jeffrey Blewett ,  Goretti Medeiros ,  Eric Finley ,  Jamil Elbanna ,  Scot Martinelli

IPC: A61B5/0488 ,  A61B20060101 ,  A61B1/00 ,  A61B5/04 ,  A61B5/0492 ,  A61B17/34 ,  A61B19/00 ,  A61B5/05

CPC classification number: A61F2/4611 ,  A61B1/32 ,  A61B5/04001 ,  A61B5/0492 ,  A61B5/4893 ,  A61B5/6828 ,  A61B5/6831 ,  A61B17/0218 ,  A61B17/3417 ,  A61B17/3421 ,  A61B17/3423 ,  A61B34/20 ,  A61B34/25 ,  A61B90/36 ,  A61B90/37 ,  A61B2017/00039 ,  A61B2017/00199 ,  A61B2017/0262 ,  A61B2034/2053 ,  A61B2034/2072 ,  A61F2/4455 ,  A61F2002/4635 ,  A61N1/0551 ,  A61N1/0553 ,  A61N1/36 ,  A61N1/36135 ,  A61N1/36142 ,  A61N1/36157 ,  A61N1/37247

Abstract: The present invention involves systems and related methods for performing surgical procedures and assessments, including the use of neurophysiology-based monitoring to: (a) determine nerve proximity and nerve direction to surgical instruments employed in accessing a surgical target site; (b) assess the pathology (health or status) of a nerve or nerve root before, during, or after a surgical procedure; and/or (c) assess pedicle integrity before, during or after pedicle screw placement, all in an automated, easy to use, and easy to interpret fashion so as to provide a surgeon-driven system.

Abstract translation: 本发明涉及用于执行外科手术和评估的系统和相关方法，包括使用基于神经生理学的监测来：（a）确定在进入手术靶位点时使用的手术器械的神经接近度和神经方向; （b）在外科手术之前，期间或之后评估神经或神经根的病理（健康或状况）; 和/或（c）在椎弓根螺钉放置之前，之中或之后评估椎弓根完整性，全部以自动化，易于使用和易于解释的方式，以提供外科医生驱动的系统。

公开(公告)号：US08672840B2

公开(公告)日：2014-03-18

申请号：US13466398

申请日：2012-05-08

Applicant: Patrick Miles ,  Scot Martinelli ,  Eric Finley ,  James Gharib ,  Allen Farquhar ,  Norbert Kaula ,  Goretti Medeiros

Inventor： Patrick Miles ,  Scot Martinelli ,  Eric Finley ,  James Gharib ,  Allen Farquhar ,  Norbert Kaula ,  Jeffrey J. Blewett

IPC: A61B1/32 ,  A61B5/0488 ,  A61B5/053

CPC classification number: A61B17/02 ,  A61B1/32 ,  A61B5/0492 ,  A61B5/4893 ,  A61B5/7405 ,  A61B5/742 ,  A61B17/0206 ,  A61B17/0218 ,  A61B17/025 ,  A61B17/0293 ,  A61B2017/00026 ,  A61B2017/00039 ,  A61B2017/0256 ,  A61B2017/0262

Abstract: A system for accessing a surgical target site and related methods, involving an initial distraction system for creating an initial distraction corridor, and an assembly capable of distracting from the initial distraction corridor to a secondary distraction corridor and thereafter sequentially receiving a plurality of retractor blades for retracting from the secondary distraction corridor to thereby create an operative corridor to the surgical target site, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.

公开(公告)号：US08512235B2

公开(公告)日：2013-08-20

申请号：US13486093

申请日：2012-06-01

Applicant: Patrick Miles ,  Scot Martinelli ,  Eric Finley ,  James Gharib ,  Allen Farquhar ,  Norbert Kaula ,  Goretti Medeiros

Inventor： Patrick Miles ,  Scot Martinelli ,  Eric Finley ,  James Gharib ,  Allen Farquhar ,  Norbert Kaula ,  Jeffrey J. Blewett

IPC: A61B1/32

CPC classification number: A61B17/025 ,  A61B1/32 ,  A61B5/0488 ,  A61B17/0218 ,  A61B17/0293 ,  A61B17/3421 ,  A61B90/37 ,  A61B2017/00261 ,  A61B2017/0256 ,  A61B2017/0262 ,  A61M29/02

Abstract: A system for accessing a surgical target site and related methods, involving an initial distraction system for creating an initial distraction corridor, and an assembly capable of distracting from the initial distraction corridor to a secondary distraction corridor and thereafter sequentially receiving a plurality of retractor blades for retracting from the secondary distraction corridor to thereby create an operative corridor to the surgical target site, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.

公开(公告)号：US08439832B2

公开(公告)日：2013-05-14

申请号：US12984368

申请日：2011-01-04

Applicant: Patrick Miles ,  Scot Martinelli ,  Eric Finley ,  James Gharib ,  Allen Farquhar ,  Norbert Kaula ,  Goretti Medeiros

Inventor： Patrick Miles ,  Scot Martinelli ,  Eric Finley ,  James Gharib ,  Allen Farquhar ,  Norbert Kaula ,  Jeffrey Blewett

IPC: A61B1/32

CPC classification number: A61B17/025 ,  A61B1/32 ,  A61B5/4893 ,  A61B17/0206 ,  A61B17/0218 ,  A61B2017/00473 ,  A61B2017/0262

Abstract: A surgical access system including a tissue distraction assembly and a tissue refraction assembly, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures before, during, and after the establishment of an operative corridor to a surgical target site.

公开(公告)号：US20120303125A1

公开(公告)日：2012-11-29

申请号：US13568236

申请日：2012-08-07

Applicant: James Gharib ,  Allen Farquhar ,  Norbert Kaula ,  Jeffrey Blewett ,  Goretti Medeiros ,  Eric Finley ,  Jamil Ebanna ,  Scot Martinelli

Inventor： James Gharib ,  Allen Farquhar ,  Norbert Kaula ,  Jeffrey Blewett ,  Goretti Medeiros ,  Eric Finley ,  Jamil Ebanna ,  Scot Martinelli

IPC: A61F2/44

CPC classification number: A61F2/4611 ,  A61B1/32 ,  A61B5/04001 ,  A61B5/0492 ,  A61B5/4893 ,  A61B5/6828 ,  A61B5/6831 ,  A61B17/0218 ,  A61B17/3417 ,  A61B17/3421 ,  A61B17/3423 ,  A61B34/20 ,  A61B34/25 ,  A61B90/36 ,  A61B90/37 ,  A61B2017/00039 ,  A61B2017/00199 ,  A61B2017/0262 ,  A61B2034/2053 ,  A61B2034/2072 ,  A61F2/4455 ,  A61F2002/4635 ,  A61N1/0551 ,  A61N1/0553 ,  A61N1/36 ,  A61N1/36135 ,  A61N1/36142 ,  A61N1/36157 ,  A61N1/37247

Abstract: The present invention involves systems and related methods for performing surgical procedures and assessments, including the use of neurophysiology-based monitoring to: (a) determine nerve proximity and nerve direction to surgical instruments employed in accessing a surgical target site; (b) assess the pathology (health or status) of a nerve or nerve root before, during, or after a surgical procedure; and/or (c) assess pedicle integrity before, during or after pedicle screw placement, all in an automated, easy to use, and easy to interpret fashion so as to provide a surgeon-driven system.

Abstract translation: 本发明涉及用于执行外科手术和评估的系统和相关方法，包括使用基于神经生理学的监测来：（a）确定在进入手术靶位点时使用的手术器械的神经接近度和神经方向; （b）在外科手术之前，期间或之后评估神经或神经根的病理（健康或状况）; 和/或（c）在椎弓根螺钉放置之前，之中或之后评估椎弓根完整性，全部以自动化，易于使用和易于解释的方式，以提供外科医生驱动的系统。