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    Preventing rogue implementations of a security-sensitive class interface
    71.
    发明授权
    Preventing rogue implementations of a security-sensitive class interface 失效
    防止安全敏感类接口的流氓实现

    公开(公告)号：US07734918B2

    公开(公告)日：2010-06-08

    申请号：US12015615

    申请日：2008-01-17

    Applicant: Peter Daniel Birk ,  Ching-Yun Chao ,  Hyen Vui Chung

    Inventor： Peter Daniel Birk ,  Ching-Yun Chao ,  Hyen Vui Chung

    IPC: H04L9/00

    CPC classification number: G06F21/64

    Abstract: A method and apparatus for preventing rogue implementations of a security-sensitive class interface are provided. With the method and apparatus, a unique identifier (UID) is created by a server process when the server process is started. Anytime the server process, i.e. a server runtime environment, instantiates a new credential object following start-up of the server process, the encrypted UID is placed into a private field within the new credential object. In addition, the UID is encrypted and stored in a private class of the server runtime environment. A verification class is provided within the server runtime environment which includes one or more methods that receive the credential object as a parameter and return true or false as to the validity of the credential object. These one or more methods determine the validity of the credential object by retrieving the encrypted UID from the private class stored in the server runtime environment, decrypting the UID and comparing it to the decrypted UID stored in the private field of the credential object. If the two UIDs match, a determination is made that the credential object was created by the server runtime environment rather than a rogue application. If the two UIDs do not match, or if there is no UID in the credential object, then a false result will be returned by the verification class.

    Abstract translation: 提供了用于防止安全敏感类接口的流氓实现的方法和装置。 使用该方法和装置，当服务器进程启动时，由服务器进程创建唯一标识符（UID）。 服务器进程（即服务器运行时环境）在服务器进程启动后实例化新的凭据对象时，加密的UID将被放置在新凭证对象内的私有字段中。 此外，UID被加密并存储在服务器运行时环境的私有类中。 在服务器运行时环境中提供了一个验证类，其中包括一个或多个接收凭证对象作为参数的方法，并返回true或false作为证书对象的有效性。 这些一个或多个方法通过从存储在服务器运行时环境中的私有类中检索加密的UID来确定凭证对象的有效性，解密UID并将其与存储在证书对象的私有字段中的解密的UID进行比较。 如果两个UID匹配，则确定凭据对象是由服务器运行时环境创建的，而不是流氓应用程序。 如果两个UID不匹配，或者如果凭证对象中没有UID，那么验证类将返回一个错误的结果。

    GDF-5 PROTEIN STORAGE
    74.
    发明申请
    GDF-5 PROTEIN STORAGE 失效
    GDF-5蛋白质储存

    公开(公告)号：US20090043078A1

    公开(公告)日：2009-02-12

    申请号：US12174168

    申请日：2008-07-16

    Applicant: Peter Daniel ,  Asok C. Sen ,  Dongling Lu

    Inventor： Peter Daniel ,  Asok C. Sen ,  Dongling Lu

    IPC: C07K14/475

    CPC classification number: A61K38/1875 ,  A61K9/0019 ,  A61K47/02 ,  A61K47/12

    Abstract: Improved compositions and methods are provided for stabilizing a solution of bone morphogenetic protein. The compositions comprise an aqueous solution of GDF-5 and a biocompatible acid, such as hydrochloric, acetic, phosphoric, or trifluoroacetic acid, wherein the solution has a pH of from about 3.0 to about 3.6, thereby providing for improved stability of the GDF-5 protein during handling and prolonged storage at reduced temperatures.

    Abstract translation: 提供改进的组合物和方法用于稳定骨形态发生蛋白的溶液。 组合物包含GDF-5的水溶液和生物相容性酸，例如盐酸，乙酸，磷酸或三氟乙酸，其中所述溶液具有约3.0至约3.6的pH，从而提供GDF- 5蛋白在处理和延长储存在降低的温度。

    AC COILED TUBING RIG WITH AUTOMATED DRILLING SYSTEM
    76.
    发明申请
    AC COILED TUBING RIG WITH AUTOMATED DRILLING SYSTEM 失效
    具有自动钻孔系统的交流绞线管

    公开(公告)号：US20070246261A1

    公开(公告)日：2007-10-25

    申请号：US11737505

    申请日：2007-04-19

    Applicant: Derek Joseph LOWE ,  Cory Jason ZIEBART ,  Peter Daniel O'BRIEN

    Inventor： Derek Joseph LOWE ,  Cory Jason ZIEBART ,  Peter Daniel O'BRIEN

    IPC: E21B44/02

    CPC classification number: E21B19/22 ,  E21B44/02

    Abstract: A method of automatic drilling of a well with coil tubing or drill pipe tubing utilizes AC motors coupled to variable frequency drives controlled by a programmable logic controller. For example, a coil tube injector is supported in a mast for injecting coil tube from a reel and into a wellbore for drilling the wellbore. The AC motors for the injector are driven for controlling a rate of injection of coil tube by the injector for maintaining at least one drilling parameter such as weight-on-bit, differential mud pressure or rate of penetration. The AC motor for the reel is also controlled for driving the reel and maintaining a relative rate of coil tube supplied from the reel to the injector. Drawworks and a top drive supported by the draworks can also be equipped with AC motors and variable frequency drives for controlling a drilling rate for maintaining at least one of the drilling parameters.

    Abstract translation: 利用线圈管或钻杆管自动钻井的方法使用耦合到由可编程逻辑控制器控制的变频驱动器的AC电动机。 例如，线圈管注射器被支撑在用于将线圈管从卷轴注入并用于钻井的井筒中的桅杆中。 用于喷射器的AC电动机被驱动以通过喷射器控制线圈管的喷射速率，用于保持至少一个钻孔参数，例如钻头重量，差异泥浆压力或渗透速率。 用于卷轴的AC电动机也被控制用于驱动卷轴并保持从卷轴供应到喷射器的线圈管的相对速率。 绞车和由绞车支撑的顶部驱动器还可以配备有交流电动机和变频驱动器，用于控制钻井速率以维持至少一个钻孔参数。

    Intelligent valve flow linearization
    77.
    发明授权
    Intelligent valve flow linearization 有权
    智能阀流量线性化

    公开(公告)号：US07096093B1

    公开(公告)日：2006-08-22

    申请号：US09503508

    申请日：2000-02-14

    Applicant: Peter Daniel Hansen ,  Bulent Goksel

    Inventor： Peter Daniel Hansen ,  Bulent Goksel

    IPC: G05D11/00

    CPC classification number: G05D7/005

    Abstract: A feed-forward flow controller is designed to calculate a target valve position from a target flow. Correction is made for liquid or gas pressure drop across the valve and for the valve flow modulating member geometry. This feed-forward action may also be used to linearize a feed-back flow control loop.

    Abstract translation: 前馈流量控制器被设计为从目标流量计算目标阀位置。 对于阀门和阀门流量调节构件几何形状的液体或气体压降进行校正。 这种前馈动作也可以用于线性化反馈流量控制回路。

    Method for the diagnosis and therapy of renal cell carcinoma
    78.
    发明申请
    Method for the diagnosis and therapy of renal cell carcinoma 审中-公开
    肾细胞癌诊断和治疗方法

    公开(公告)号：US20050053931A1

    公开(公告)日：2005-03-10

    申请号：US10479200

    申请日：2002-05-30

    Applicant: Peter Daniel ,  Bernhard Gillissen

    Inventor： Peter Daniel ,  Bernhard Gillissen

    IPC: A61K38/17 ,  A61P13/12 ,  C12N15/861 ,  G01N33/574 ,  C12Q1/68 ,  G01N33/53 ,  G01N33/567

    CPC classification number: C12N15/86 ,  A61K38/1709 ,  C12N2710/10343 ,  C12N2830/006 ,  G01N33/57438

    Abstract: The invention relates to a novel approach for the diagnosis and therapy of renal cell carcinoma, and other renal tumors, for example Wilms' tumor or other tumors not originating from the kidney or non-malignant kidney pathologies. The areas of application of the invention include the field of medicine and the pharmaceutical industry but also basic biology. The aim of the invention is to provide novel forms of treatment which are urgently required regarding the present state-of-the-art in treatment of renal carcinoma and other cancers. It was discovered that the Nbk protein which is highly expressed in normal renal tissue, is either not expressed at all or only weakly expressed in the tumor tissue. The protein expression and the loss of Nbk was examined in renal cell carcinoma samples by the use of immunohistochemistry, PCR strategies, mutation and deletion analyses. The inventive method for diagnosis is characterized by that the Nbk protein concentration or the Nbk RNA quantity or Nbk mutation or deletion or Nbk gene modification, preferentially methylation, in tissue-derived material is determined. The inventive agent for the therapy of the renal carcinoma and other cells with low Nbk protein or RNA expression is that Nbk expression is increased and directly initiates the therapeutic effect in these cells. The implementation of a novel agent in non-tumorous kidney diseases is based on the inhibition of Nbk RNA or protein expression or Nbk activity.

    Abstract translation: 本发明涉及用于诊断和治疗肾细胞癌和其它肾肿瘤的新方法，例如Wilms肿瘤或其他不源自肾脏或非恶性肾脏病变的肿瘤。 本发明的应用领域包括医药领域和制药业，也是基础生物学领域。 本发明的目的是提供关于治疗肾癌和其他癌症的现有技术最迫切需要的新型治疗形式。 发现在正常肾组织中高度表达的Nbk蛋白质或者在肿瘤组织中完全不表达或仅表达弱表达。 通过免疫组织化学，PCR方法，突变和缺失分析，检测肾细胞癌样品中蛋白质的表达和损失。 本发明的诊断方法的特征在于确定组织来源材料中的Nbk蛋白浓度或Nbk RNA量或Nbk突变或缺失或Nbk基因修饰，优先甲基化。 用于治疗肾癌和其他具有低Nbk蛋白或RNA表达的细胞的本发明剂是增加Nbk的表达，并直接引发这些细胞的治疗效果。 在非肿瘤性肾脏疾病中实施新型药物是基于抑制Nbk RNA或蛋白质表达或Nbk活性的。

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