公开(公告)号：USD507853S1

公开(公告)日：2005-07-26

申请号：US29176674

申请日：2003-02-26

申请人： Stacey Main ,  Christopher Murray

设计人： Stacey Main ,  Christopher Murray

公开(公告)号：US20050152073A1

公开(公告)日：2005-07-14

申请号：US11030787

申请日：2005-01-07

申请人： Charles Black ,  Stephen Gates ,  Christopher Murray ,  Robert Sandstrom

发明人： Charles Black ,  Stephen Gates ,  Christopher Murray ,  Robert Sandstrom

IPC分类号： G01R33/09 ,  G11B5/33 ,  G11B5/127

CPC分类号： B82Y25/00 ,  G01R33/093 ,  Y10T29/49032 ,  Y10T29/49069 ,  Y10T29/49155 ,  Y10T428/25 ,  Y10T428/265

摘要： A magnetic-field sensor device comprises at least two electrodes; an insulating layer separating the at least two electrodes; at least one layer of chemically-synthesized magnetic nanoparticles disposed at or above a level with the insulating layer, and disposed between the at least two electrodes; and an organic spacer surrounding each of the chemically-synthesized magnetic nanoparticles. A deviation between diameters of different ones of the nanoparticles is less than 15%. Moreover, the chemically-synthesized magnetic nanoparticles range in size between 2 nm and 20 nm in diameter.

摘要翻译： 磁场传感器装置包括至少两个电极; 分离所述至少两个电极的绝缘层; 至少一层化学合成的磁性纳米颗粒设置在与绝缘层的水平面上或之上，并且设置在至少两个电极之间; 以及围绕每个化学合成的磁性纳米颗粒的有机间隔物。 不同纳米颗粒的直径之间的偏差小于15％。 此外，化学合成的磁性纳米粒子的尺寸范围在2nm和20nm之间。

公开(公告)号：US20050102393A1

公开(公告)日：2005-05-12

申请号：US10712130

申请日：2003-11-12

申请人： Christopher Murray ,  John Zamick

发明人： Christopher Murray ,  John Zamick

IPC分类号： G06F20060101 ,  G06F15/173 ,  H04L29/06 ,  H04L29/08

CPC分类号： H04L67/1008 ,  H04L29/06 ,  H04L63/0892 ,  H04L67/1002 ,  H04L67/101 ,  H04L67/1025 ,  H04L67/1029 ,  H04L67/1034 ,  H04L67/1036 ,  H04L2029/06054

摘要： The invention provides techniques for adaptive load balancing. Techniques are provided for monitoring a server's operating conditions; determining, based on the server's operating conditions, when to send a behavior modification hint to one or more clients that are being served by the server; generating the behavior modification hint based on the server's operating conditions; and sending the behavior modification hint to the one or more clients. A client receives the behavior modification hint and, based on the behavior modification hint, alters a timeout value related to the server or alters its preferred server.

摘要翻译： 本发明提供了用于自适应负载平衡的技术。 提供技术来监控服务器的运行状况; 基于服务器的操作条件确定何时向由服务器服务的一个或多个客户端发送行为修改提示; 根据服务器的运行状况生成行为修改提示; 并向一个或多个客户端发送行为修改提示。 客户端接收行为修改提示，并根据行为修改提示更改与服务器相关的超时值或更改其首选服务器。

公开(公告)号：US20050056937A1

公开(公告)日：2005-03-17

申请号：US10662709

申请日：2003-09-15

申请人： David Frank ,  Kathryn Guarini ,  Christopher Murray ,  Xinlin Wang ,  Hon-Sum Wong

发明人： David Frank ,  Kathryn Guarini ,  Christopher Murray ,  Xinlin Wang ,  Hon-Sum Wong

IPC分类号： H01L23/522 ,  H01L23/525 ,  H01L23/48

CPC分类号： H01L23/525 ,  H01L23/5226 ,  H01L2924/0002 ,  H01L2924/3011 ,  H01L2924/00

摘要： A connection device includes a plurality of re-configurable vias that connect a first metal layer to a second metal layer. An actuating element is disposed between the first metal layer and the second metal layer. The actuating element changes the configuration of the plurality of re-configurable vias to change the plurality of re-configurable vias between a conductive state and a non-conductive state.

摘要翻译： 连接装置包括将第一金属层连接到第二金属层的多个可重新配置的通孔。 致动元件设置在第一金属层和第二金属层之间。 致动元件改变多个可重新配置的通孔的配置，以改变导电状态和非导通状态之间的多个可重新配置的通孔。

公开(公告)号：US20050056643A1

公开(公告)日：2005-03-17

申请号：US10900906

申请日：2004-07-28

申请人： Luke Hagan ,  Christopher Murray

发明人： Luke Hagan ,  Christopher Murray

IPC分类号： A45C7/00

CPC分类号： A45C7/0077

摘要： A folding storage bin is positionable between an open position and a closed position via a drawstring. A plurality of side members are attached to an exterior side of a liner, and a drawstring is threaded through the side members and the liner. In the open position, pulling the drawstring brings the side members into a facing relationship disposed substantially end-to-end. In a preferred arrangement, the liner is sized and shaped such that in the closed position, a flexible pocket is formed between adjacent ends of the side members. The pockets prevent small parts from falling out of the corners of the bin and help to prevent smaller items from getting caught in the bin corners, which would prevent the bin from closing properly.

摘要翻译： 折叠储物箱可通过束带定位在打开位置和关闭位置之间。 多个侧构件附接到衬套的外侧，并且束带穿过侧构件和衬套。 在打开位置，拉动拉绳带使侧部构件基本上端对端设置成面对的关系。 在优选的布置中，衬套的尺寸和形状使得在关闭位置中，在侧构件的相邻端部之间形成柔性袋。 口袋可防止小零件从箱体角落脱落，有助于防止较小的物品被卡在箱子角落，这样可以防止垃圾桶正常关闭。

公开(公告)号：USD492263S1

公开(公告)日：2004-06-29

申请号：US29191797

申请日：2003-10-14

申请人： Christopher Murray

设计人： Christopher Murray

公开(公告)号：US6004997A

公开(公告)日：1999-12-21

申请号：US197944

申请日：1998-11-23

申请人： Qun Y. Zheng ,  Christopher Murray ,  Randall J. Daughenbaugh ,  Poonsakdi Ploypradith ,  Gary H. Posner

发明人： Qun Y. Zheng ,  Christopher Murray ,  Randall J. Daughenbaugh ,  Poonsakdi Ploypradith ,  Gary H. Posner

IPC分类号： C07D519/00 ,  A61K31/335

CPC分类号： C07D519/00

摘要： Novel trioxane dimers of structure ##STR1## which possess antiproliferative and antitumor activities.

摘要翻译： 具有抗增殖和抗肿瘤活性的新型三恶烷二聚体结构。

公开(公告)号：US20130302358A1

公开(公告)日：2013-11-14

申请号：US13876266

申请日：2011-10-03

申请人： Joshua E. Collins ,  Howard Y. Bell ,  Xingchen Ye ,  Christopher Murray

发明人： Joshua E. Collins ,  Howard Y. Bell ,  Xingchen Ye ,  Christopher Murray

IPC分类号： C09K11/77 ,  B42D15/00 ,  C30B7/08

CPC分类号： C09K11/7791 ,  B42D15/00 ,  B82Y30/00 ,  C01F17/0031 ,  C01F17/0043 ,  C01F17/0062 ,  C01F17/0087 ,  C01P2002/52 ,  C01P2002/54 ,  C01P2002/72 ,  C01P2002/84 ,  C01P2004/04 ,  C01P2004/10 ,  C01P2004/11 ,  C01P2004/16 ,  C01P2004/20 ,  C01P2004/32 ,  C01P2004/40 ,  C01P2004/42 ,  C01P2004/52 ,  C01P2004/62 ,  C01P2004/64 ,  C09K11/7773 ,  C30B7/08 ,  Y10T428/2933

摘要： Monodisperse particles having: a single pure crystalline phase of a rare earth-containing lattice, a uniform three-dimensional size, and a uniform polyhedral morphology are disclosed. Due to their uniform size and shape, the monodisperse particles self assemble into superlattices. The particles may be luminescent particles such as down-converting phosphor particles and up-converting phosphors. The monodisperse particles of the invention have a rare earth-containing lattice which in one embodiment may be an yttrium-containing lattice or in another may be a lanthanide-containing lattice. The monodisperse particles may have different optical properties based on their composition, their size, and/or their morphology (or shape). Also disclosed is a combination of at least two types of monodisperse particles, where each type is a plurality of monodisperse particles having a single pure crystalline phase of a rare earth-containing lattice, a uniform three-dimensional size, and a uniform polyhedral morphology; and where the types of monodisperse particles differ from one another by composition, by size, or by morphology. In a preferred embodiment, the types of monodisperse particles have the same composition but different morphologies. Methods of making and methods of using the monodisperse particles are disclosed.

摘要翻译： 公开了具有：含有稀土晶格的单一纯晶相，均匀的三维尺寸和均匀的多面体形态的单分散颗粒。 由于其均匀的尺寸和形状，单分散颗粒自组装成超晶格。 颗粒可以是发光颗粒，例如下转换荧光体颗粒和上转换荧光体。 本发明的单分散颗粒具有含稀土晶格，在一个实施方案中可以是含钇的晶格，或者另一个可以是含镧系元素的晶格。 基于它们的组成，它们的尺寸和/或其形态（或形状），单分散颗粒可以具有不同的光学性质。 还公开了至少两种类型的单分散颗粒的组合，其中每种类型是具有单一纯结晶相的含稀土晶格的单分散颗粒，均匀的三维尺寸和均匀的多面体形态; 并且其中单分散颗粒的类型通过组成，尺寸或形态彼此不同。 在优选的实施方案中，单分散颗粒的类型具有相同的组成但不同的形态。 公开了制备方法和使用单分散颗粒的方法。

公开(公告)号：US08101648B2

公开(公告)日：2012-01-24

申请号：US11911490

申请日：2006-04-13

申请人： Gianni Chessari ,  Miles Stuart Congreve ,  Eva Figueroa Navarro ,  Martyn Frederickson ,  Christopher Murray ,  Alison Jo-Anne Woolford ,  Maria Grazia Carr ,  Michael Alistair O'Brien ,  Andrew James Woodhead ,  Robert Downham ,  Theresa Rachel Phillips

发明人： Gianni Chessari ,  Miles Stuart Congreve ,  Eva Figueroa Navarro ,  Martyn Frederickson ,  Christopher Murray ,  Alison Jo-Anne Woolford ,  Maria Grazia Carr ,  Michael Alistair O'Brien ,  Andrew James Woodhead ,  Robert Downham ,  Theresa Rachel Phillips

IPC分类号： A01N43/38 ,  A61K31/40 ,  C07D209/44

CPC分类号： C07D401/12 ,  C07C65/21 ,  C07D209/08 ,  C07D209/44 ,  C07D215/08 ,  C07D217/06 ,  C07D401/04 ,  C07D401/10 ,  C07D401/14 ,  C07D403/04 ,  C07D413/04 ,  C07D413/06 ,  C07D413/12 ,  C07D413/14 ,  C07D471/04 ,  C07D471/10 ,  C07D491/08 ,  C07D491/10

摘要： The invention provides compounds of the formula (I): or salts, tautomers, solvates and N-oxides thereof; wherein R1 is hydrogen; R2 is hydroxy or methoxy; R3 is selected from hydrogen; halogen; cyano; optionally substituted C1-5 hydrocarbyl and optionally substituted C1-5 hydrocarbyloxy; R4 is selected from hydrogen; a group —(O)n—R7 where n is 0 or 1 and R7 is an optionally substituted acyclic C1-5 hydrocarbyl group or a monocyclic carbocyclic or heterocyclic group having 3 to 7 ring members; halogen; cyano; hydroxy; amino; and optionally substituted mono- or di-C1-5 hydrocarbyl-amino; or R3 and R4 together form a monocyclic carbocyclic or heterocyclic ring of 5 to 7 ring members; and NR5R6 forms an optionally substituted bicyclic heterocyclic group having 8 to 12 ring members of which up to 5 ring members are heteroatoms selected from oxygen, nitrogen and sulphur. The compounds have activity as Hsp90 inhibitors.

摘要翻译： 本发明提供式（I）的化合物：或其盐，互变异构体，溶剂合物和N-氧化物; 其中R1是氢; R2是羟基或甲氧基; R3选自氢; 卤素; 氰基; 任选取代的C 1-5烃基和任选取代的C 1-5烃氧基; R4选自氢; 其中n为0或1，R7为任选取代的无环C 1-5烃基或具有3至7个环成员的单环碳环或杂环基团 - （O）n -R 7基团; 卤素; 氰基; 羟基; 氨基; 和任选取代的单或二-C 1-5烃基 - 氨基; 或R 3和R 4一起形成5至7个环成员的单环碳环或杂环; 并且NR 5 R 6形成具有8至12个环成员的任选取代的双环杂环基，其中多达5个环成员是选自氧，氮和硫的杂原子。 该化合物具有作为Hsp90抑制剂的活性。

公开(公告)号：US07847120B2

公开(公告)日：2010-12-07

申请号：US11112389

申请日：2005-04-22

申请人： Al Quick ,  Antonio M. Santos ,  Alexandre J G G Carvalho ,  Douglas G. Johnson ,  Jeffrey B. Etter ,  Christopher Murray

发明人： Al Quick ,  Antonio M. Santos ,  Alexandre J G G Carvalho ,  Douglas G. Johnson ,  Jeffrey B. Etter ,  Christopher Murray

IPC分类号： C07C229/00 ,  C07C65/03

CPC分类号： A61K31/195

摘要： The present invention provides novel compositions of allosteric hemoglobin modifiers which are substantially free of impurities, specifically polymeric impurities. In one embodiment, the novel compositions contain an allosteric hemoglobin modifier compound and less than 100 ppm of the polymeric impurities generated during the preparation of this compound. Included in the present invention are novel methods for preparing allosteric hemoglobin modifiers that are substantially free of polymeric impurities. Also included in the present invention are improved methods for the purification of the product formed by the method of this invention. The novel methods of purification comprise extracting the crude composition with a water immiscible or partially immiscible solvent such as methylisobutyl ketone (MIBK) to lower amounts of impurities, specifically polymeric impurities. Also included are methods to reduce impurities by recrystallization of the crude synthesized product, followed by filtration of the recrystallized product. The present invention also includes the products made by the processes of the invention and methods for analyzing compositions comprised of these products.

摘要翻译： 本发明提供基本上不含杂质，特别是聚合物杂质的变构血红蛋白改性剂的新型组合物。 在一个实施方案中，新型组合物含有变构血红蛋白改性剂化合物，并且在制备该化合物期间产生小于100ppm的聚合物杂质。 本发明包括制备基本上不含聚合物杂质的变构型血红蛋白改性剂的新方法。 本发明还包括用于纯化通过本发明方法形成的产品的改进方法。 新颖的纯化方法包括用与水不混溶或部分不混溶的溶剂如甲基异丁基酮（MIBK）提取粗组合物以降低杂质量，特别是聚合物杂质。 还包括通过粗合成产物的重结晶减少杂质的方法，然后过滤重结晶产物。 本发明还包括通过本发明的方法制备的产品和用于分析由这些产品组成的组合物的方法。