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71.发明授权Method and apparatus for treating irregular ventricular contractions such as during atrial arrhythmia 有权用于治疗不规则心室收缩的方法和装置，例如在心房心律失常期间公开(公告)号：US08064997B2
公开(公告)日：2011-11-22
申请号：US11423516
申请日：2006-06-12
IPC分类号： A61N1/362
CPC分类号： A61N1/3956 , A61N1/3622 , A61N1/395
摘要： A cardiac rhythm management system is capable of treating irregular ventricular heart contractions, such as during atrial tachyarrhythmias such as atrial fibrillation. A first indicated pacing interval is computed based at least partially on a most recent V-V interval duration between ventricular beats and a previous value of the first indicated pacing interval. Pacing therapy is provided based on either the first indicated pacing interval or also based on a second indicated pacing interval, such as a sensor-indicated pacing interval. A weighted averager such as an infinite impulse response (IIR) filter adjusts the first indicated pacing interval for sensed beats and differently adjusts the first indicated pacing interval for paced beats. The system regularizes ventricular rhythms by pacing the ventricle, but inhibits pacing when the ventricular rhythms are stable.
摘要翻译： 心律管理系统能够治疗不规则的心室心脏收缩，例如在房性快速性心律失常如心房颤动期间。 至少部分地基于心室搏动之间的最新V-V间期持续时间和第一个起搏间隔的先前值来计算第一个起搏间隔。 基于第一个起搏间隔或基于第二个起搏间隔（例如传感器指示的起搏间隔）来提供起搏疗法。 诸如无限脉冲响应（IIR）滤波器的加权平均器调节感测节拍的第一个起搏间隔，并且针对起搏节奏不同地调节第一个起搏间隔。 系统通过起搏心室使心室节律正常化，但是当心室节律稳定时，可抑制起搏。
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公开(公告)号：US08053740B2
公开(公告)日：2011-11-08
申请号：US13044003
申请日：2011-03-09
IPC分类号： G01T1/00
CPC分类号： A61N1/37 , A61N1/3718
摘要： An implantable medical apparatus comprises a solid state electronic circuit, an ionizing radiation exposure sensor, an ionizing radiation dose rate sensor, and a controller circuit. The ionizing radiation exposure sensor is configured to detect an exposure of the solid state electronic circuit to ionizing radiation, and generate an indication of a non-single-event-upset (non-SEU) effect to the solid state electronic circuit from the exposure to ionizing radiation, wherein the sensor comprises an accumulated ionizing radiation exposure sensor. The controller circuit is configured to blank the indication from the accumulated ionizing radiation exposure sensor when the radiation dose rate sensor indicates that flux ionizing radiation exceeds a flux ionizing radiation threshold.
摘要翻译： 一种可植入医疗装置，包括固态电子电路，电离辐射曝光传感器，电离辐射剂量率传感器和控制器电路。 电离辐射曝光传感器被配置为检测固态电子电路对电离辐射的曝光，并且产生对固态电子电路的非单事件不适（非SEU）效应的指示，从曝光到 电离辐射，其中所述传感器包括累积的电离辐射曝光传感器。 控制器电路被配置为当辐射剂量率传感器指示通量电离辐射超过通量电离辐射阈值时，从累积的电离辐射曝光传感器中消除指示。
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73.发明申请公开(公告)号：US20110201955A1
公开(公告)日：2011-08-18
申请号：US13094597
申请日：2011-04-26
IPC分类号： A61B5/08
CPC分类号： A61B7/003 , A61N1/36514 , A61N1/36535
摘要： Adventitious lung sounds indicative of lung congestion are detected using an implantable sensor. The sensor is adapted to be positioned adjacent to a pulmonary system and to output signals indicative of lung sounds in response to pulmonary system activity. A controller receives the signals and processes the signals to detect the presence of adventitious lung sounds. A respiratory cycle sensor operating in conjunction with the lung-sound sensor enables classification of an adventitious lung sound according to its time occurrence within the respiratory cycle. Posture sensing in conjunction with lung-sound sensing provides valuable additional information as to the severity of the lung congestion.
摘要翻译： 使用植入式传感器检测到指示肺充血的不定肺声。 传感器适于邻近肺部系统定位，并响应于肺部系统活动而输出指示肺部声音的信号。 控制器接收信号并处理信号以检测不定肺声的存在。 与肺声传感器一起操作的呼吸循环传感器可以根据呼吸周期内的时间发生分类不定肺声。 结合肺部感觉的姿势感知提供了关于肺充血严重程度的有价值的附加信息。
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公开(公告)号：US20110178566A1
公开(公告)日：2011-07-21
申请号：US13075244
申请日：2011-03-30
申请人： Jeffrey E. Stahmann , Bruce Tockman , Randy Westlund , Rene H. Wentkowski , Russell E. Anderson
发明人： Jeffrey E. Stahmann , Bruce Tockman , Randy Westlund , Rene H. Wentkowski , Russell E. Anderson
IPC分类号： A61N1/365
CPC分类号： A61N1/36514 , A61N1/3622 , A61N1/365 , A61N1/368 , A61N1/3712
摘要： A method for allowing cardiac signals to be sensed and pacing pulse vectors to be delivered between two or more electrodes. In one embodiment, cardiac signals are sensed and pacing pulse vectors are delivered between at least one of a first left ventricular electrode and a second left ventricular electrode. Alternatively, cardiac signals are sensed and pacing pulse vectors are delivered between different combinations of the first and second left ventricular electrodes and a first supraventricular electrode. In addition, cardiac signals are sensed and pacing pulse vectors are delivered between different combinations of the first and second left ventricular electrode, the first supraventricular electrode and a conductive housing. In an additional embodiment, a first right ventricular electrode is used to sense cardiac signals and provide pacing pulses with different combinations of the first and second left ventricular electrodes, the first supraventricular electrode and the housing.
摘要翻译： 一种用于允许感测心脏信号的方法和用于在两个或更多个电极之间递送起搏脉冲矢量的方法。 在一个实施例中，感测心脏信号，并且起搏脉冲矢量在第一左心室电极和第二左心室电极中的至少一个之间递送。 或者，感测心脏信号，并且起搏脉冲矢量在第一和第二左心室电极和第一室上电极的不同组合之间递送。 此外，感测心脏信号，并且起搏脉冲矢量在第一和第二左心室电极，第一室上电极和导电壳体的不同组合之间递送。 在另外的实施例中，第一右心室电极用于感测心脏信号并且提供具有第一和第二左心室电极，第一室上电极和外壳的不同组合的起搏脉冲。
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75.发明申请公开(公告)号：US20110163834A1
公开(公告)日：2011-07-07
申请号：US12977172
申请日：2010-12-23
IPC分类号： H01F17/04
CPC分类号： H01F41/00 , H01F1/344 , H01F3/02 , H01F27/245 , H01F2003/106 , Y10T29/4902
摘要： This document discusses, among other things, an inductive component that can include a core having two portions: (1) a first portion composed of a first material having a first magnetic saturation level; and (2) a second portion composed of a second material selected to provide inductance for the inductive component when an external magnetic field is greater than the first magnetic saturation level. In an example, the first portion can be composed of a material having a relatively low magnetic saturation level (e.g., a ferrite), and the second portion can be composed of a material having a relatively high magnetic saturation level (e.g., a high permeability iron alloy).
摘要翻译： 本文件尤其涉及可包括具有两部分的芯的电感元件：（1）由具有第一磁饱和电平的第一材料组成的第一部分; 和（2）由外部磁场大于第一磁饱和度的第二材料组成的第二部分，该第二材料被选择为提供电感元件的电感。 在一个示例中，第一部分可以由具有相对低的磁饱和度的材料（例如，铁氧体）组成，并且第二部分可以由具有较高磁饱和度的材料（例如，高磁导率 铁合金）。
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76.发明申请APPARATUS TO SELECTIVELY INCREASE MEDICAL DEVICE LEAD INNER CONDUCTOR INDUCTANCE 有权选择性增加医疗器械引导内导体电感的设备公开(公告)号：US20110160816A1
公开(公告)日：2011-06-30
申请号：US12905336
申请日：2010-10-15
摘要： A medical device lead includes an insulative lead body, outer and inner conductive coils, and a flexible core assembly. The outer conductive coil extends through the lead body and is coupled to a first electrode at a distal end of the outer conductive coil. The inner conductive coil extends coaxially with the outer conductive coil, is coupled to a second electrode at a distal end of the inner conductive coil, and includes a central lumen. The flexible core assembly is disposed in the central lumen and is comprised of a material that has a saturation magnetization of at least about 1.5 T and a relative permeability of greater than one. The flexible core assembly includes a positioning interface configured for manipulation of the flexible core assembly such that the flexible core assembly translates through the central lumen during insertion and extraction of the flexible core assembly.
摘要翻译： 医疗器械引线包括绝缘引线体，外部和内部导电线圈以及柔性芯组件。 外部导电线圈延伸穿过引线体并且在外部导电线圈的远端处耦合到第一电极。 与外部导电线圈同轴地延伸的内部导电线圈耦合到内部导电线圈的远端处的第二电极，并且包括中心腔。 柔性芯组件设置在中心腔中，并且由具有至少约1.5T的饱和磁化强度和大于1的相对磁导率的材料构成。 柔性芯组件包括配置用于操纵柔性芯组件的定位接口，使得柔性芯组件在插入和拔出柔性芯组件期间通过中心腔平移。
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公开(公告)号：US20110160808A1
公开(公告)日：2011-06-30
申请号：US12977158
申请日：2010-12-23
IPC分类号： A61N1/36
CPC分类号： A61N1/37 , A61N1/086 , A61N1/3706 , A61N1/3718 , A61N1/37258 , A61N1/3752 , A61N2001/083
摘要： An implantable medical device can include a hermetically-sealed implantable housing, an exposed first conductor located on or near the housing, and at least one insulated second conductor located near the exposed first conductor. In an example, the implantable medical device can include an isolation test circuit to provide a test stimulus to the exposed first conductor and configured to measure a portion of the test stimulus coupled to the second conductor.
摘要翻译： 可植入医疗装置可以包括密封的可植入壳体，位于壳体上或附近的暴露的第一导体，以及位于暴露的第一导体附近的至少一个绝缘的第二导体。 在一个示例中，可植入医疗设备可以包括隔离测试电路，以向暴露的第一导体提供测试刺激，并且被配置为测量耦合到第二导体的测试刺激的一部分。
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公开(公告)号：US20110144712A1
公开(公告)日：2011-06-16
申请号：US12966249
申请日：2010-12-13
CPC分类号： A61N1/36585 , A61N1/36 , A61N1/362 , A61N1/3627 , A61N1/365
摘要： Intermittent delivery of ventricular pacing pulses synchronized to occur during an atrial diastole time period can be used to provide atrial stretch therapy and augment the production and release of atrial natriuretic hormone.
摘要翻译： 间歇性输送心房舒张期同步发生的心室起搏脉冲可用于提供心房伸展疗法，并增加心房钠尿激素的产生和释放。
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公开(公告)号：US20110112592A1
公开(公告)日：2011-05-12
申请号：US13007739
申请日：2011-01-17
CPC分类号： A61N1/36114 , A61N1/3962
摘要： Various aspects of the present subject matter relate to a system. Various embodiments of the system comprise at least one port to connect to at least one lead with at least one electrode, at least one stimulator circuit and at least one controller. The at least one stimulator circuit is connected to the at least one port and is adapted to deliver neural stimulation to a neural stimulation target using the at least one electrode. The at least one controller is adapted to determine when another energy discharge other than the neural stimulation to the neural stimulation target is occurring and to prevent delivery of the neural stimulation simultaneously with the other energy discharge. Other aspects and embodiments are provided herein.
摘要翻译： 本主题的各个方面涉及系统。 系统的各种实施例包括至少一个端口，以连接至少一个引线与至少一个电极，至少一个刺激器电路和至少一个控制器。 所述至少一个刺激器电路连接到所述至少一个端口，并且适于使用所述至少一个电极将神经刺激递送到神经刺激靶。 所述至少一个控制器适于确定何时发生除了对神经刺激靶的神经刺激以外的其他能量放电，并且防止神经刺激与另一能量放电同时传送。 本文提供了其它方面和实施例。
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80.发明授权公开(公告)号：US07865241B2
公开(公告)日：2011-01-04
申请号：US12176861
申请日：2008-07-21
IPC分类号： A61N1/368
CPC分类号： A61N1/3627 , A61N1/3684
摘要： A device and method for cardiac rhythm management in which a heart chamber is paced in accordance with a pacing mode that employs sense signals from the opposite chamber. A protection period triggered by the sensing of intrinsic activity in the paced chamber is used to inhibit pacing without otherwise disturbing the pacing algorithm.
摘要翻译： 一种用于心律管理的装置和方法，其中心室根据采用来自相对室的感测信号的起搏模式而起搏。 通过感觉起搏室内部活动触发的保护期限被用于抑制起搏而不打扰起搏算法。
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