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1.发明申请公开(公告)号：US20110201955A1
公开(公告)日：2011-08-18
申请号：US13094597
申请日：2011-04-26
IPC分类号： A61B5/08
CPC分类号： A61B7/003 , A61N1/36514 , A61N1/36535
摘要： Adventitious lung sounds indicative of lung congestion are detected using an implantable sensor. The sensor is adapted to be positioned adjacent to a pulmonary system and to output signals indicative of lung sounds in response to pulmonary system activity. A controller receives the signals and processes the signals to detect the presence of adventitious lung sounds. A respiratory cycle sensor operating in conjunction with the lung-sound sensor enables classification of an adventitious lung sound according to its time occurrence within the respiratory cycle. Posture sensing in conjunction with lung-sound sensing provides valuable additional information as to the severity of the lung congestion.
摘要翻译： 使用植入式传感器检测到指示肺充血的不定肺声。 传感器适于邻近肺部系统定位，并响应于肺部系统活动而输出指示肺部声音的信号。 控制器接收信号并处理信号以检测不定肺声的存在。 与肺声传感器一起操作的呼吸循环传感器可以根据呼吸周期内的时间发生分类不定肺声。 结合肺部感觉的姿势感知提供了关于肺充血严重程度的有价值的附加信息。
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公开(公告)号：US20100076336A1
公开(公告)日：2010-03-25
申请号：US12628384
申请日：2009-12-01
申请人： Jeffrey E. Stahmann , John Hatlestad , Boyce Moon
发明人： Jeffrey E. Stahmann , John Hatlestad , Boyce Moon
IPC分类号： A61B5/053
CPC分类号： A61B5/053 , A61N1/3627 , A61N1/36521
摘要： This document discusses, among other things, a cardiac rhythm management device or other implantable medical device that uses thoracic impedance to determine how much fluid is present in the thorax, such as for detecting or predicting congestive heart failure, pulmonary edema, pleural effusion, hypotension, or the like. The thoracic fluid amount determined from the thoracic impedance is compensated for changes in blood resistivity, which may result from changes in hematocrit level or other factors. The blood-resistivity-compensated thoracic fluid amount can be stored in the device or transmitted to an external device for storage or display. The blood-resistivity-compensated thoracic fluid amount can also be used to adjust a cardiac pacing, cardiac resynchronization, or other cardiac rhythm management or other therapy to the patient. This document also discusses applications of the devices and methods for predicting or indicating anemia.
摘要翻译： 本文件尤其涉及一种使用胸部阻抗来确定胸部存在多少液体的心律管理装置或其他可植入医疗装置，例如用于检测或预测充血性心力衰竭，肺水肿，胸腔积液，低血压 ，等等。 根据胸部阻抗确定的胸腔液量补偿血液电阻率的变化，这可能是血细胞比容水平的变化或其他因素引起的。 血液电阻补偿的胸腔液量可以存储在设备中或者传输到外部设备进行存储或显示。 血液电阻补偿的胸液量也可用于调整心脏起搏，心脏再同步或其他心律控制或对患者的其他治疗。 本文件还讨论了用于预测或指示贫血的装置和方法的应用。
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3.发明申请CALIBRATION OF IMPEDANCE MONITORING OF RESPIRATORY VOLUMES USING THORACIC D.C. IMPEDANCE 有权使用THORACIC D.C.阻抗校正呼吸道阻力监测公开(公告)号：US20090326599A1
公开(公告)日：2009-12-31
申请号：US12557372
申请日：2009-09-10
CPC分类号： A61N1/36521 , A61B5/0809 , A61B2560/0223 , A61N1/3756
摘要： A system includes an implantable medical device that includes a trans-thoracic impedance measurement circuit providing a trans-thoracic impedance signal of a subject. A controller is coupled to the trans-thoracic impedance circuit. The controller extracts a respiration signal from the trans-thoracic impedance signal, measures a breathing volume of the subject using the amplitude of the respiration signal and a breathing volume calibration factor, computes an adjusted breathing volume calibration factor using a reference baseline value of the trans-thoracic impedance and a measured baseline value of the trans-thoracic impedance, and computes a calibrated breathing volume using the adjusted breathing volume calibration factor.
摘要翻译： 一种系统包括可植入医疗装置，其包括提供受试者的胸部阻抗信号的跨胸阻抗测量电路。 控制器耦合到跨胸阻抗电路。 控制器从胸部阻抗信号中提取呼吸信号，使用呼吸信号的幅度和呼吸音量校准因子来测量受试者的呼吸体积，使用反式信号的参考基准值计算调整后的呼吸量校准因子 胸廓阻抗和经胸阻抗的测量基线值，并使用调整后的呼吸量校准因子计算校准呼吸量。
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公开(公告)号：US20080249433A1
公开(公告)日：2008-10-09
申请号：US12139948
申请日：2008-06-16
申请人： Jeffrey E. Stahmann , John Hatlestad , Boyce Moon
发明人： Jeffrey E. Stahmann , John Hatlestad , Boyce Moon
IPC分类号： A61B5/053
CPC分类号： A61B5/053 , A61N1/3627 , A61N1/36521
摘要： This document discusses, among other things, a cardiac rhythm management device or other implantable medical device that uses thoracic impedance to determine how much fluid is present in the thorax, such as for detecting or predicting congestive heart failure, pulmonary edema, pleural effusion, hypotension, or the like. The thoracic fluid amount determined from the thoracic impedance is compensated for changes in blood resistivity, which may result from changes in hematocrit level or other factors. The blood-resistivity-compensated thoracic fluid amount can be stored in the device or transmitted to an external device for storage or display. The blood-resistivity-compensated thoracic fluid amount can also be used to adjust a cardiac pacing, cardiac resynchronization, or other cardiac rhythm management or other therapy to the patient. This document also discusses applications of the devices and methods for predicting or indicating anemia.
摘要翻译： 本文件尤其涉及一种使用胸部阻抗来确定胸部存在多少液体的心脏节律管理装置或其他可植入医疗装置，例如用于检测或预测充血性心力衰竭，肺水肿，胸腔积液，低血压 ，等等。 根据胸部阻抗确定的胸腔液量补偿血液电阻率的变化，这可能是血细胞比容水平的变化或其他因素引起的。 血液电阻补偿的胸腔液量可以存储在设备中或者传输到外部设备进行存储或显示。 血液电阻补偿的胸液量也可用于调整心脏起搏，心脏再同步或其他心律控制或对患者的其他治疗。 本文件还讨论了用于预测或指示贫血的装置和方法的应用。
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公开(公告)号：US20110275942A1
公开(公告)日：2011-11-10
申请号：US13185203
申请日：2011-07-18
IPC分类号： A61B5/0205 , A61B5/0402
CPC分类号： A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/053 , A61B5/0816 , A61B5/0826 , A61B5/091 , A61B5/1116 , A61B5/1118 , A61B5/4878 , A61B5/686 , A61B5/746 , A61B7/02 , A61N1/08
摘要： An embodiment of a device for reporting a heart failure status of a patient comprises: a parameter acquisition module configured to acquire at least one trended heart failure parameter; a predetermined event acquisition module configured to acquire at least one predetermined event corresponding to the at least one trended heart failure parameter, wherein each of the at least one predetermined event represents an event condition where a predetermined event definition is satisfied; an alert acquisition module configured to acquire at least one heart failure status alert associated with the at least one predetermined event, wherein each of the at least one alert represents an alert condition where a predetermined alert definition is satisfied; and an output communication module configured to communicate the at least one heart failure status alert.
摘要翻译： 用于报告患者的心力衰竭状态的装置的实施例包括：参数获取模块，被配置为获取至少一个趋势性心力衰竭参数; 预定事件获取模块，被配置为获取与所述至少一个趋势性心力衰竭参数相对应的至少一个预定事件，其中所述至少一个预定事件中的每一个表示满足预定事件定义的事件条件; 警报采集模块，被配置为获取与所述至少一个预定事件相关联的至少一个心力衰竭状态警报，其中所述至少一个警报中的每一个表示满足预定警报定义的警报状况; 以及输出通信模块，被配置为通信所述至少一个心力衰竭状态警报。
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6.发明授权公开(公告)号：US07983759B2
公开(公告)日：2011-07-19
申请号：US10323606
申请日：2002-12-18
IPC分类号： A61N1/37
CPC分类号： A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/053 , A61B5/0816 , A61B5/0826 , A61B5/091 , A61B5/1116 , A61B5/1118 , A61B5/4878 , A61B5/686 , A61B5/746 , A61B7/02 , A61N1/08
摘要： Systems, devices and methods for reporting multiple health-related parameters are disclosed. One aspect is a programmable device having machine executable instructions for performing a method to report multiple parameters related to a health condition of a patient. In various embodiments, a number of trended health-related parameters, a number of predetermined events corresponding to the number of trended health-related parameters, and a number of alerts associated with the predetermined events are acquired. The number of trended health-related parameters, the number of predetermined events, and the number of alerts are communicated in a manner suitable for use in determining the health condition of the patient. Other aspects and embodiments are provided herein.
摘要翻译： 公开了用于报告多个健康相关参数的系统，设备和方法。 一个方面是具有用于执行报告与患者的健康状况相关的多个参数的方法的机器可执行指令的可编程设备。 在各种实施例中，获取多个趋势健康相关参数，对应于趋势健康相关参数的数量的预定事件的数量以及与预定事件相关联的警报的数量。 趋势健康相关参数的数量，预定事件的数量和警报的数量以适合用于确定患者的健康状况的方式传达。 本文提供了其它方面和实施例。
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公开(公告)号：US07979115B2
公开(公告)日：2011-07-12
申请号：US11972405
申请日：2008-01-10
IPC分类号： A61B5/05
CPC分类号： A61B5/0205 , A61B5/0031 , A61B5/0535 , A61B5/1116 , A61B5/4869 , A61N1/36521 , A61N1/36535
摘要： This patent document discusses systems, devices, and methods for increasing a sensitivity or specificity of thoracic fluid detection in a subject and differentiating between pleural effusion and pulmonary edema. In one example, a thoracic impedance measurement circuit senses a thoracic impedance signal. In another example, a processor receives the thoracic impedance signal and determines whether such thoracic impedance signal is “significant.” A significant thoracic impedance signal indicates the presence of thoracic fluid and may be recognized by comparing the thoracic impedance signal (or variation thereof) to a thoracic impedance threshold. When a significant thoracic impedance signal is recognized, the processor is adapted to detect one or both of: a pleural effusion indication and a pulmonary edema indication using one or a combination of: physiologic information, patient symptom information, and posture information. In another example, the thoracic impedance threshold is adjusted using such physiologic, patient symptom, or posture information.
摘要翻译： 该专利文献讨论了用于增加受试者胸部液体检测的敏感性或特异性并区分胸腔积液和肺水肿的系统，装置和方法。 在一个示例中，胸部阻抗测量电路感测胸部阻抗信号。 在另一示例中，处理器接收胸部阻抗信号并确定这种胸部阻抗信号是否“显着”。显着的胸部阻抗信号表示胸腔存在，并且可以通过将胸部阻抗信号（或其变化）与 胸阻抗阈值。 当识别出显着的胸部阻抗信号时，处理器适合于使用生理信息，患者症状信息和姿势信息中的一个或组合来检测胸腔积液指示和肺水肿指示之一或两者。 在另一个例子中，使用这种生理，患者症状或姿势信息来调整胸阻抗阈值。
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8.发明申请公开(公告)号：US20110144526A1
公开(公告)日：2011-06-16
申请号：US13033081
申请日：2011-02-23
IPC分类号： A61B5/053
CPC分类号： A61B5/0537 , A61B5/0002 , A61B5/0538 , A61B5/4869 , A61B5/4878
摘要： This patent document discusses, among other things, systems, devices, and methods for enhancing detection of pulmonary edema using, in addition to thoracic impedance, one or a combination of: physiologic information about a subject, at least one statistical parameter, a user-programmable detection level, at least one parameter associated with a previous pulmonary edema event, and patient symptom information about the subject. In one example, a (base) thoracic impedance threshold is modified to an adjusted thoracic impedance threshold. The adjusted thoracic impedance threshold provides an increased sensitivity of pulmonary edema detection as compared to the base thoracic impedance threshold. In another example, an alert is provided to a subject, a caregiver, or other user based on a pulmonary edema indication determined by the present systems, devices, and methods. In a further example, a therapy (provided to the subject) is adjusted or initiated in response to the pulmonary edema indication.
摘要翻译： 该专利文献尤其涉及用于增强肺水肿检测的系统，装置和方法，除胸部阻抗之外，还包括以下之一或组合：关于受试者的生理信息，至少一个统计参数， 可编程检测水平，与先前的肺水肿事件相关联的至少一个参数，以及关于受试者的患者症状信息。 在一个示例中，（基底）胸部阻抗阈值被修改为经调整的胸部阻抗阈值。 与基础胸廓阻抗阈值相比，经调整的胸廓阻抗阈值提供了肺水肿检测的灵敏度增加。 在另一示例中，基于由本系统，设备和方法确定的肺水肿指示，向受检者，照顾者或其他用户提供警报。 在另一个实例中，响应于肺水肿指示调整或启动治疗（提供给受试者）。
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公开(公告)号：US07127291B2
公开(公告)日：2006-10-24
申请号：US10087377
申请日：2002-03-01
IPC分类号： A61N1/00
CPC分类号： A61N1/056 , A61N1/08 , A61N2001/0585
摘要： A lead system is provided including a coronary sinus lead extending from a proximal end to a distal end, where the lead includes at least one thermal sensor, or optionally, a thermistor. The thermal sensor is positionable within a coronary sinus of a heart when the coronary sinus lead is implanted in the heart to measure the temperature of a myocardium. The method includes coupling at least one thermal sensor with the implantable lead, including coupling a first thermal sensor and a second thermal sensor with the lead, placing the implantable lead and at least one thermal sensor within a coronary sinus of a heart and positioning the first thermal sensor within the coronary sinus, and positioning the second thermal sensor within a right atrium of a heart. The method further includes coupling the implantable lead with the implantable electrical stimulation source, and measuring a myocardium temperature.
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10.发明授权Advanced patient management for triaging health-related data using color codes 有权高级患者管理，用于使用颜色代码对健康相关数据进行分类公开(公告)号：US08043213B2
公开(公告)日：2011-10-25
申请号：US10323607
申请日：2002-12-18
IPC分类号： A61B5/00
CPC分类号： A61B5/0031 , A61B5/7264 , A61N1/37252 , A61N1/37282 , G06F19/00 , G06F19/3418 , G16H10/60 , G16H15/00
摘要： Systems, devices and methods for triaging health-related data, such as significant health-related events associated with health-related parameters, are disclosed. One aspect is a method for use in managing a patient's health within a patient management system. In various embodiments of the method, a number of predetermined events are accessed. The events are related to the patient's health and are identified by the patient management system. Each of the predetermined events are classified according to severity using a color-code system. In various embodiments, a red event is an imminent life threatening event, a yellow event is a serious health-related condition that is not imminently life threatening, and a green event is an event that is neither an imminent life threatening event nor a serious health-related condition. Other aspects and embodiments are provided herein.
摘要翻译： 公开了用于分类健康相关数据的系统，设备和方法，例如与健康相关参数相关的重大健康相关事件。 一个方面是用于在患者管理系统内管理患者健康的方法。 在该方法的各种实施例中，访问多个预定事件。 这些事件与患者的健康有关，并由患者管理系统确定。 使用颜色代码系统根据严重性对每个预定事件进行分类。 在各种实施方案中，红色事件是迫在眉睫的威胁生命的事件，黄色事件是严重的健康相关状况，不是迫在眉睫的生命危险，绿色事件是既不是迫在眉睫的生命危险事件也不是严重健康的事件 相关条件。 本文提供了其它方面和实施例。
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