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公开(公告)号：US11320379B2
公开(公告)日：2022-05-03
申请号：US16074331
申请日：2016-04-21
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Ning Ge , Milo Overbay , James Abbott , Anita Rogacs , Viktor Shkolnikov
IPC: G01N21/64 , B82Y15/00 , B82Y40/00 , G01N21/65 , B05D5/08 , B82Y30/00 , C23C16/44 , C23C16/455 , C23C16/50
Abstract: A surface enhanced luminescence (SELS) sensor may include a substrate and nano fingers projecting from the substrate. Each of the nano fingers may include a polymer pillar having a sidewall and a top, a coating layer covering the sidewall and a metal cap supported by and in contact with the top of the pillar.
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公开(公告)号：US11318469B2
公开(公告)日：2022-05-03
申请号：US16606287
申请日：2018-04-25
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： Viktor Shkolnikov , Chien-Hua Chen
Abstract: An example system includes a microfluidic cavity; a retaining feature within the microfluidic cavity, and a releasing feature. The retaining feature is to position capsules at a predetermined location in the microfluidic cavity. The capsules have a thermally degradable shell enclosing a material therein. The releasing feature is to selectively cause degradation of the shell to release the material into the microfluidic opening. The releasing feature is to generate heat to facilitate degradation of the shell. In some examples, the retaining feature is a physical barrier sized to prevent flow of the capsule and to allow flow of the released materials through the microfluidic cavity.
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公开(公告)号：US11278887B2
公开(公告)日：2022-03-22
申请号：US16493241
申请日：2017-04-21
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： Viktor Shkolnikov , Michael W. Cumbie , Chien-Hua Chen
IPC: B01L3/00
Abstract: A microfluidic device is provided that includes a substrate and microfluidic sub-chips embedded in the substrate. An electric field is applied between an adjacent pair microfluidic sub-chips to move a fluid droplet from one of the adjacent pair of microfluidic sub-chips to another of the adjacent pair microfluidic sub-chips.
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公开(公告)号：US20220080422A1
公开(公告)日：2022-03-17
申请号：US17417615
申请日：2019-02-12
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Viktor Shkolnikov , Alexander Govyadinov
IPC: B01L3/00
Abstract: The present disclosure relates to a microfluidic particle concentrator that includes an inlet microchannel, a filtering chamber fluidly connected to the inlet microchannel to receive a sample fluid, and a mechanical filter positioned in the filtering chamber. The particle concentrator also includes a filter outlet microchannel fluidly connected to the filtering chamber to receive a particle-ablated fluid formed by passing through the mechanical filter, a particle outlet microchannel fluidly connected to the filtering chamber to receive a particle-concentrated fluid including a plurality of particles not permitted to pass through the mechanical filter, and a fluid movement network including multiple pumps. The multiple fluid pumps generate sample fluid flow through the inlet microchannel and into the filtering chamber, particle-ablated fluid flow from the mechanical filter into the filter outlet microchannel, and particle-concentrated fluid from the filtering chamber into the particle outlet microchannel.
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公开(公告)号：US20220080421A1
公开(公告)日：2022-03-17
申请号：US17414155
申请日：2019-05-13
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Viktor Shkolnikov , Alexander Govyadinov , Diane R. Hammerstad
Abstract: A system includes a microchannel analysis region, a first fluid actuation device, a second fluid actuation device, a sensor, and a controller. The first fluid actuation device is at a first end of the microchannel analysis region. The second fluid actuation device is at a second end of the microchannel analysis region opposite to the first end. The sensor is within the microchannel analysis region between the first fluid actuation device and the second fluid actuation device. The sensor measures an impedance of a fluid within the microchannel analysis region. The controller activates the first fluid actuation device to generate a first pressure wave in the fluid and activates the second fluid actuation device to generate a second pressure wave in the fluid. The first pressure wave and the second pressure wave converge at the sensor.
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Patent Agency Ranking
公开(公告)号：US20220074843A1
公开(公告)日：2022-03-10
申请号：US17415130
申请日：2019-05-30
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Viktor Shkolnikov , DAIXI XIN , Yang Lei
Abstract: A particle monitoring system may include a flow passage, a particle imager to image a targeted particle within the flow passage, electrodes supported proximate the flow passage, a power source connected to the electrodes and a controller to cause the power source to charge to electrodes so as to (1) apply an electric field balanced with respect to gravity so as to hold, levitate and rotate a targeted particle within the flow passage during imaging and (2) release the targeted particle following the imaging
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公开(公告)号：US20220018755A1
公开(公告)日：2022-01-20
申请号：US17413706
申请日：2019-01-13
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Viktor Shkolnikov , Diane R. Hammerstad
Abstract: A particle classification system may include a volume to contain a fluid having a suspended particle, electrodes proximate the volume to apply an electric field to rotate the suspended particle, a focused light source, a scattered light sensor to sense light from the focused light source that has scattered upon impinging the rotating suspended particle and a controller to classify the particle based at least in part upon signals from the scattered light sensor.
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公开(公告)号：US11198841B2
公开(公告)日：2021-12-14
申请号：US16076545
申请日：2017-06-09
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： Viktor Shkolnikov , Kenneth Ward
Abstract: A microfluidic device may include a microfluidic channel including an electrode placed at opposite ends of the microfluidic channel to create an electrical field within the channel and an ejection device to eject at least one cell porated within the electrical field. A cassette may include a substrate, a die coupled to the substrate, a microfluidic channel defined within the die, the microfluidic channel including a necked portion to receive a cell therein and at least two electrodes each placed at a first and a second end of the microfluidic channel to apply an electric field to the cell above a proration threshold and a cell ejection device to eject the cell from the die.
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公开(公告)号：US20210362156A1
公开(公告)日：2021-11-25
申请号：US16606241
申请日：2018-07-16
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： Viktor Shkolnikov , Chien-Hua Chen
IPC: B01L3/00
Abstract: An example of an apparatus includes a focusing region to focus a sheath fluid and a particle flow. The apparatus also includes a particle inlet to inject the particle flow into the focusing region. In addition, the apparatus includes a sheath inlet to inject the sheath fluid into the focusing region. Also, the apparatus includes a cut-out disposed on a wall of the sheath inlet to distribute the sheath fluid about the particle flow to focus the particle flow into a linear stream. The apparatus further includes a separation region to apply a force to the particle flow. The force is dependent on a characteristic of a particle in the particle flow.
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公开(公告)号：US20210262937A1
公开(公告)日：2021-08-26
申请号：US17256681
申请日：2018-10-29
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Viktor Shkolnikov , Fausto D'Apuzzo , Yang Lei
Abstract: An example apparatus includes a well plate having an array of wells, a light encoding layer positioned under the well plate, an imaging layer to capture an image of the well plate encoded by the light encoding layer, an array of electrodes positioned on a surface of a bottom floor of the at least one well, and a controller. The light encoding layer is to encode light passing through a microscopic object in at least one well of the array of wells. The light encoding layer has a substantially flat form. The controller is to direct electrical voltage to the electrodes to generate a non-rotating, non-uniform electrical field, the electrical field being to rotate an object in the electrical field.
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