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289 条记录 (耗时 0.047 秒)

    Self-expanding stent with time variable radial force
    71.
    发明授权
    Self-expanding stent with time variable radial force 有权
    具有时间可变径向力的自扩张支架

    公开(公告)号：US06663664B1

    公开(公告)日：2003-12-16

    申请号：US09697894

    申请日：2000-10-26

    申请人： Stephen D. Pacetti

    发明人： Stephen D. Pacetti

    IPC分类号： A61F206

    CPC分类号： A61F2/91 ,  A61F2/915 ,  A61F2002/91516 ,  A61F2002/91533 ,  A61F2002/91575 ,  A61F2002/9511 ,  A61F2210/0004

    摘要： A stent including a network of struts constructed to form a structural member. The struts are configured with undulations having flexible segments that bend to move the structural member from a collapsed or delivery position to an expanded position. A biodegradable material is associated with the flexible segments of the stent struts to change the bending characteristics of the segments and, thus, alter the amount of contraction and expansion exhibited by the stent. The biodegradable material is selected to degrade under certain biological conditions over time so as to vary the resistance to movement effect of the material on the flexible segments of the struts.

    摘要翻译： 一种支架，其包括构造成形成结构构件的支柱网。 支柱配置有具有弯曲以将结构构件从折叠或递送位置移动到展开位置的柔性段的起伏。 可生物降解的材料与支架支柱的柔性段相关联，以改变段的弯曲特性，从而改变支架展示的收缩和膨胀的量。 选择生物可降解材料在某些生物条件下随着时间的推移而降解，以便改变材料对支柱柔性段上的运动效应的抵抗力。

    Vacuum chamber and apparatus for loading material into a stent strut
    77.
    发明授权
    Vacuum chamber and apparatus for loading material into a stent strut 有权
    真空室和将材料装入支架支架的装置

    公开(公告)号：US09238514B2

    公开(公告)日：2016-01-19

    申请号：US13035815

    申请日：2011-02-25

    申请人： Stephen D. Pacetti

    发明人： Stephen D. Pacetti

    IPC分类号： A61F2/86 ,  B65B3/00 ,  A61F2/88

    CPC分类号： A61F2/915 ,  A61F2/86 ,  A61F2/88 ,  A61F2240/002 ,  A61F2250/0068 ,  A61F2250/0069 ,  B65B3/003 ,  B65B31/04

    摘要： An apparatus for loading material into a stent strut can comprise a chamber capable of maintaining an internal pressure below pressure external to the chamber. The chamber carries within it the stent and the material to be loaded into a lumen within the stent strut. Pressure within the chamber is decreased. The decreased pressure can draw the material into lumen. The decreased pressure can draw air out of the lumen so that, after a subsequent increase in pressure in the chamber, the material is drawn into the lumen.

    摘要翻译： 用于将材料装载到支架支柱中的装置可以包括能够将内部压力保持在室外的压力的室。 腔室内承载支架和待装载到支架支架内腔内的材料。 室内的压力降低。 降低的压力可将材料吸入内腔。 减小的压力可以将空气抽出管腔，使得在腔室中随后的压力增加之后，材料被吸入管腔中。

    Method and system to maintain a fixed distance during coating of a medical device
    78.
    发明授权
    Method and system to maintain a fixed distance during coating of a medical device 有权
    在医疗器械涂层期间保持固定距离的方法和系统

    公开(公告)号：US09084874B2

    公开(公告)日：2015-07-21

    申请号：US13158131

    申请日：2011-06-10

    申请人： Binh Nguyen ,  Benjamyn Serna ,  Stephen D. Pacetti ,  Victoria M. Gong

    发明人： Binh Nguyen ,  Benjamyn Serna ,  Stephen D. Pacetti ,  Victoria M. Gong

    IPC分类号： B05C5/02 ,  B05B13/04 ,  B05C13/02 ,  A61M25/10

    CPC分类号： A61M25/1029 ,  A61M2025/1031 ,  A61M2025/105 ,  B05B13/0442 ,  B05C5/02

    摘要： Method and system to coat an expandable member of a medical device comprising a support structure to support the expandable member and an applicator positioned with at least one outlet proximate a surface of an expandable member. A drive assembly establishes relative movement between the at least one outlet and the surface of the expandable member to apply fluid on the surface of the expandable member along a coating path. A tracking mechanism maintains a substantially fixed distance between the at least one outlet and the surface of the expandable member during relative movement therebetween by displacing the at least one outlet relative to the expandable member.

    摘要翻译： 涂覆医疗装置的可扩张构件的方法和系统，包括支撑结构以支撑可膨胀构件以及位于靠近可扩张构件的表面的至少一个出口的施用器。 驱动组件在至少一个出口和可膨胀构件的表面之间建立相对运动，以沿着涂覆路径向可扩张构件的表面施加流体。 跟踪机构通过相对于可扩展构件移位至少一个出口而在相对移动期间在至少一个出口和可扩张构件的表面之间保持基本固定的距离。

    Methods of drug loading a hollow stent with a high viscosity formulation
    80.
    发明授权
    Methods of drug loading a hollow stent with a high viscosity formulation 有权
    药物加载具有高粘度制剂的中空支架的方法

    公开(公告)号：US08927047B2

    公开(公告)日：2015-01-06

    申请号：US13035803

    申请日：2011-02-25

    申请人： Stephen D. Pacetti

    发明人： Stephen D. Pacetti

    IPC分类号： B05D3/00 ,  A61L33/00 ,  A61F2/06 ,  A61B5/00 ,  A61L31/08 ,  A61L31/16 ,  A61F2/91

    CPC分类号： A61L31/082 ,  A61F2/91 ,  A61F2250/0068 ,  A61L31/16 ,  A61L2300/416 ,  C08L67/04

    摘要： A method of loading a composition into a structural element of a stent, where the structural element is defined by a lumen and at least one opening to access the lumen. The composition may include a therapeutic agent. In some embodiments, the composition has characteristics such that at a temperature of 20° C. to 30° C. and a pressure of one atmosphere, the viscosity of the composition is about 10 cP or greater than 10 cP.

    摘要翻译： 一种将组合物装载到支架的结构元件中的方法，其中结构元件由腔和至少一个开口限定，以进入内腔。 组合物可以包括治疗剂。 在一些实施方案中，组合物具有这样的特征，使得在20℃至30℃的温度和一个大气压下，组合物的粘度为约10cP或大于10cP。