公开(公告)号：US20110282161A1

公开(公告)日：2011-11-17

申请号：US13190142

申请日：2011-07-25

Applicant: Prashant Bhadri ,  James Lescoulie ,  Sophia Fang ,  Matthew McCormick ,  Ralph Kems ,  Mark Humayun ,  Aaron Barnes

Inventor： Prashant Bhadri ,  James Lescoulie ,  Sophia Fang ,  Matthew McCormick ,  Ralph Kems ,  Mark Humayun ,  Aaron Barnes

IPC: A61B1/06

CPC classification number: A61B3/13

Abstract: A first light source producing a first light beam with a first intensity and a second light source producing a second light beam with a second intensity. A light filter device receives the first light beam and transmits a filtered portion of the first light beam. A first angling device reflects the filtered portion of the first light beam in a first angled direction and a second angling device reflects the second light beam in a second angled direction. A mirror receives and in turn reflects the filtered portion of the first light beam reflected by the first angling device and the second light beam reflected by the second angling device to form a converged light beam with a third intensity.

Abstract translation: 产生具有第一强度的第一光束的第一光源和产生具有第二强度的第二光束的第二光源。 光过滤器装置接收第一光束并透射第一光束的滤波部分。 第一倾斜装置以第一倾斜方向反射第一光束的过滤部分，而第二垂直装置以第二倾斜方向反射第二光束。 反射镜接收反射由第一钓鱼装置反射的第一光束的过滤部分和由第二钓鱼装置反射的第二光束，以形成具有第三强度的会聚光束。

公开(公告)号：US20110282160A1

公开(公告)日：2011-11-17

申请号：US13106780

申请日：2011-05-12

Applicant: Prashant Bhadri ,  Ralph Kerns ,  Jaw-Chyng Lormen Lue ,  Matthew McCormick ,  Mark Humayun

Inventor： Prashant Bhadri ,  Ralph Kerns ,  Jaw-Chyng Lormen Lue ,  Matthew McCormick ,  Mark Humayun

IPC: A61B1/06

CPC classification number: A61F9/0017 ,  A61B1/0684 ,  A61B1/07 ,  A61B1/313 ,  A61B3/0008 ,  A61B17/0218 ,  A61B17/0231 ,  A61B17/3421 ,  A61B17/3423 ,  A61B17/3462 ,  A61B2017/0225 ,  A61B2090/306 ,  A61B2090/309 ,  A61F9/0026 ,  A61F9/007 ,  A61F9/00736

Abstract: A cannula is described having a housing, a first lumen, a second lumen, and a port capable of fluid communication with the first lumen. The second lumen configured to receive fluid from the first lumen and to direct the fluid to a surgical site. A light emitting diode light source is positionable within the housing and configured to direct light through the second lumen to the surgical site.

Abstract translation: 描述了具有壳体，第一腔，第二腔和能够与第一腔流体连通的端口的插管。 构造成从第一管腔接收流体并将流体引导到手术部位的第二腔。 发光二极管光源可定位在壳体内并且被配置为将光引导通过第二内腔到外科手术部位。

公开(公告)号：US08050745B2

公开(公告)日：2011-11-01

申请号：US11508734

申请日：2006-08-22

Applicant: Sean Caffey ,  Mark Humayun

Inventor： Sean Caffey ,  Mark Humayun

IPC: A61B6/00

CPC classification number: G02B21/0012 ,  A61B90/20 ,  A61B90/30 ,  A61B90/36 ,  A61B90/361 ,  A61F9/007 ,  G02B23/12

Abstract: The present invention employs image intensification for medical procedures within the human body. Methods and systems of the invention utilize infrared radiation (e.g. greater than about 750 nm) illumination and visualization of a surgical treatment area. Preferred methods and systems of the invention incorporate use of an infrared radiation visualization system which may be known as “night vision” systems.

Abstract translation: 本发明对人体内的医疗程序采用图像增强。 本发明的方法和系统利用外科治疗区域的红外辐射（例如大于约750nm）的照明和可视化。 本发明的优选方法和系统结合使用可被称为“夜视”系统的红外辐射可视化系统。

公开(公告)号：US20110190690A1

公开(公告)日：2011-08-04

申请号：US13084471

申请日：2011-04-11

Applicant: Mark Humayun ,  Charles DeBoer ,  Ralph Kerns ,  Matthew McCormick ,  Prashant Bhadri ,  Lawrence Chong

Inventor： Mark Humayun ,  Charles DeBoer ,  Ralph Kerns ,  Matthew McCormick ,  Prashant Bhadri ,  Lawrence Chong

IPC: A61F9/007 ,  A61B19/02

CPC classification number: A61F9/00736 ,  A61B18/1206 ,  A61B50/33 ,  A61B90/30 ,  A61B90/98 ,  A61B2017/00199 ,  A61B2017/00221 ,  A61B2017/00225 ,  A61B2017/0023 ,  A61B2017/00544 ,  A61B2017/00734 ,  A61B2018/00601 ,  A61B2050/3008 ,  A61F9/00745

Abstract: A biological tissue cutting and fluid aspiration system provides a plurality of surgical instruments operable independent of an external control console. In some embodiments, each surgical instrument may include all sensors and controls directly applicable to the surgical instrument, and may be used independently. In some embodiments, instruments communicate status information to each other, and adjust operating parameters based on the communications.

Abstract translation: 生物组织切割和流体抽吸系统提供可独立于外部控制台操作的多个外科器械。 在一些实施例中，每个外科器械可以包括直接适用于外科器械的所有传感器和控制器，并且可以独立地使用。 在一些实施例中，仪器彼此通信状态信息，并且基于通信来调整操作参数。

公开(公告)号：US20100268013A1

公开(公告)日：2010-10-21

申请号：US12792005

申请日：2010-06-02

Applicant: Charles E. Larsen ,  Richard A. Hillstead ,  Roelof Trip ,  Eugene deJuan ,  Mark Humayun ,  Eberhard Fritz ,  Rainer Pintaske

Inventor： Charles E. Larsen ,  Richard A. Hillstead ,  Roelof Trip ,  Eugene deJuan ,  Mark Humayun ,  Eberhard Fritz ,  Rainer Pintaske

IPC: A61M36/04

CPC classification number: A61N5/1017

Abstract: A method for performing intraocular brachytherapy and an apparatus for performing the same is disclosed. The apparatus preferably comprises a hand-held delivery device that advances a radiation source into an associated cannula or probe that is positioned adjacent the target tissue. The handpiece provides for shielded storage of the radiation source when retracted from the cannula and includes a slider mechanism for advancing and retracting the radiation source. The radiation source is mounted to a wire that has a flexible distal end and a relatively stiffer proximal end. A positioning system for the cannula is also disclosed.

Abstract translation: 公开了一种用于进行眼内近距离放射治疗的方法及其执行装置。 该装置优选地包括将辐射源前进到与靶组织相邻定位的相关套管或探针中的手持递送装置。 所述手持件在从套管缩回时提供辐射源的屏蔽存储，并且包括用于前进和后退辐射源的滑块机构。 辐射源安装到具有柔性远端和较硬的近端的导线上。 还公开了用于套管的定位系统。

公开(公告)号：US20100076271A1

公开(公告)日：2010-03-25

申请号：US12427345

申请日：2009-04-21

Applicant: Mark Humayun

Inventor： Mark Humayun

IPC: A61F9/007 ,  A61M25/00 ,  A61B1/06

CPC classification number: A61M1/008 ,  A61B2090/3614 ,  A61B2090/3937 ,  A61F9/007 ,  A61M13/003 ,  A61M2210/0612

Abstract: A surgical device having a body portion that is gripped by a user, the body portion having a distal end equipped with a soft tip and the proximal end optionally connected to an external vacuum or gas/air source. The surgical device is particularly suitable for use in ophthalmic surgical procedures to remove fluid from the eye or introduce gas/air into the eye. The soft tip is fabricated to protect the delicate tissues if the eye and is further modified so as to enhance a user's visibility of the device in the surgical field.

Abstract translation: 一种手术装置，其具有被使用者抓握的主体部分，所述主体部分具有配备有软尖端的远端，并且所述近端可选地连接到外部真空或气体/空气源。 手术装置特别适合用于眼科外科手术以从眼睛中除去流体或将气体/空气引入眼睛。 制造软尖端以保护精细的组织，如果眼睛被进一步修改以增强使用者在手术领域中的装置的可视性。

公开(公告)号：US20100004639A1

公开(公告)日：2010-01-07

申请号：US12463254

申请日：2009-05-08

Applicant: Changlin Pang ,  Fukang Jiang ,  Jason Shih ,  Sean Caffey ,  Mark Humayun ,  Yu-Chong Tai

Inventor： Changlin Pang ,  Fukang Jiang ,  Jason Shih ,  Sean Caffey ,  Mark Humayun ,  Yu-Chong Tai

IPC: A61K9/22

CPC classification number: A61F9/00781 ,  A61F9/0017 ,  A61M5/1408 ,  A61M5/142 ,  A61M5/14276 ,  A61M5/14593 ,  A61M5/16886 ,  A61M39/24 ,  A61M2005/14204 ,  A61M2005/14264 ,  A61M2205/0244 ,  A61M2210/0612 ,  B44C1/227 ,  Y10T156/1092 ,  Y10T156/1093 ,  Y10T307/625

Abstract: Embodiments of an implantable electrolytic pump include an electrolysis chamber, a drug chamber and an osmosis chamber, the osmosis chamber having a first portion in contact with the drug chamber and a second portion exposed to facilitate contact with a surrounding fluid. The pump further includes a cannula for conducting liquid from the drug chamber and electrolysis electrodes within the electrolysis chamber for causing generation of a gas therein, the electrolysis and drug chambers being in contact such that gas electrolysis within electrolysis chamber forces fluid from the drug chamber into the cannula, contact between the drug chamber and the osmosis chamber permitting fluid admitted into the osmotic chamber from the surrounding fluid to offset volume loss from the drug chamber and prevent buildup of vacuum pressure thereon.

Abstract translation: 可植入电解泵的实施例包括电解室，药物室和渗透室，渗透室具有与药物室接触的第一部分和暴露于便于与周围流体接触的第二部分。 泵还包括用于从药物腔室导出液体的插管和电解室内的电解电极，用于在其中产生气体，电解和药物室接触，使得电解室内的气体电解迫使来自药物室的流体进入 插管，药物室和渗透室之间的接触，允许从周围流体进入渗透室的流体以抵消药物室的体积损失并防止其上的真空压力的累积。

公开(公告)号：US20090312742A1

公开(公告)日：2009-12-17

申请号：US12463251

申请日：2009-05-08

Applicant: Changlin Pang ,  Fukang Jiang ,  Jason Shih ,  Sean Caffey ,  Mark Humayun ,  Yu-Chong Tai

Inventor： Changlin Pang ,  Fukang Jiang ,  Jason Shih ,  Sean Caffey ,  Mark Humayun ,  Yu-Chong Tai

IPC: A61M5/142

CPC classification number: A61F9/00781 ,  A61F9/0017 ,  A61M5/1408 ,  A61M5/142 ,  A61M5/14276 ,  A61M5/14593 ,  A61M5/16886 ,  A61M39/24 ,  A61M2005/14204 ,  A61M2005/14264 ,  A61M2205/0244 ,  A61M2210/0612 ,  B44C1/227 ,  Y10T156/1092 ,  Y10T156/1093 ,  Y10T307/625

Abstract: Embodiments of an implantable electrolytic pump include a first expandable diaphragm and a second flexible diaphragm, and first and second chambers each for containing a fluid, wherein the first expandable diaphragm separates the first and second chambers and provides a fluid barrier therebetween, and the second chamber is formed between the first expandable diaphragm and the second flexible diaphragms. The pump may further include electrolysis electrodes within the first chamber for causing generation of a gas therein and to thereby expand the expandable diaphragm so that fluid is forced from the second chamber into a cannula.

Abstract translation: 可植入电解泵的实施例包括第一可膨胀隔膜和第二柔性隔膜，以及每个用于容纳流体的第一和第二室，其中第一可膨胀隔膜分隔第一和第二室并在其间提供流体阻挡物，第二室 形成在第一可膨胀膜片和第二柔性膜片之间。 泵还可以包括在第一室内的电解电极，用于在其中产生气体，从而使可膨胀隔膜膨胀，使得流体被迫从第二室进入套管。

公开(公告)号：US20090143734A1

公开(公告)日：2009-06-04

申请号：US12256420

申请日：2008-10-22

Applicant: Mark Humayun ,  Charles DeBoer ,  Matthew McCormick ,  Prashant Bhadri ,  Joel Cicchella ,  Ralph Kerns

Inventor： Mark Humayun ,  Charles DeBoer ,  Matthew McCormick ,  Prashant Bhadri ,  Joel Cicchella ,  Ralph Kerns

IPC: A61B19/02 ,  A61M1/00 ,  A61B17/00

CPC classification number: A61F9/00736 ,  A61B50/33 ,  A61B90/30 ,  A61B90/40 ,  A61B2017/00544 ,  A61B2017/00734 ,  A61B2017/00973 ,  A61F9/00763 ,  A61M3/0262 ,  A61M2205/123 ,  A61M2205/3553 ,  A61M2205/3561 ,  A61M2205/505

Abstract: A sterile surgical tray includes structure for receiving a plurality of surgical instruments, a pump fluid reservoir within the tray, a pump contained within the sterile tray and connected to the pump fluid reservoir, and a motor contained within the sterile tray and connected to the pump. Sterile surgical tray 10 also may include electrical input and output connectors attached to tray.

Abstract translation: 无菌手术托盘包括用于容纳多个外科器械的结构，托盘内的泵流体储存器，容纳在无菌托盘内并连接到泵流体储存器的泵以及容纳在无菌托盘内并连接到泵的马达 。 无菌手术托盘10还可以包括附接到托盘的电输入和输出连接器。

公开(公告)号：US20080305320A1

公开(公告)日：2008-12-11

申请号：US12041652

申请日：2008-03-03

Applicant: Lucien Laude ,  Adrian Rowley ,  Mark Humayun ,  James Weiland

Inventor： Lucien Laude ,  Adrian Rowley ,  Mark Humayun ,  James Weiland

IPC: B32B27/16

CPC classification number: C08J7/123 ,  C08J2383/04 ,  Y10T428/249987

Abstract: The invention provides a method of activating a silicone polymer surface using a laser, particularly an excimer laser, so that the silicone is more reactive. A silicone article containing an activated surface is also provided, and can be used to make silicone implants that can be securely fixed to tissue. One example is an implantable prosthesis to treat blindness caused by outer retinal degenerative diseases. The device bypasses damaged photoreceptors and electrically stimulates the undamaged neurons of the retina. Electrical stimulation is achieved using a silicone microelectrode array (MEA). A safe, protein adhesive is used in attaching the MEA to the retinal surface and assist in alleviating focal pressure effects.

Abstract translation: 本发明提供使用激光器，特别是准分子激光器激活硅氧烷聚合物表面的方法，使得硅氧烷更具反应性。 还提供了含活化表面的硅胶制品，可用于制造可固定固定在组织上的硅胶植入物。 一个例子是用于治疗由视网膜外变性疾病引起的失明的可植入假体。 该装置绕过受损的光感受器并电刺激视网膜的未损伤的神经元。 使用硅微电极阵列（MEA）实现电刺激。 使用安全的蛋白质粘合剂将MEA附着到视网膜表面并有助于减轻焦点压力的影响。