公开(公告)号：US20090041665A1

公开(公告)日：2009-02-12

申请号：US11578647

申请日：2004-04-14

Applicant: Shu Wang ,  Ying Li

Inventor： Shu Wang ,  Ying Li

IPC: A61K35/76 ,  A61K49/00 ,  A61P25/00

CPC classification number: C12N15/86 ,  A61K47/6901 ,  A61K48/0075 ,  C12N2710/14143

Abstract: The present invention relates to the use of axonal transport to deliver a baculovirus vector to a target neuronal cell by administering the vector to a site that is remote from the target cell. Such delivery allows for tracing of neuronal pathways and further a baculovirus vector may be used to deliver therapeutic gene to a target neuronal which may otherwise be not readily accessible, for the treatment of a neuronal disorder in a subject.

Abstract translation: 本发明涉及使用轴突转运通过将该载体施用于远离目标细胞的位点将杆状病毒载体递送至目标神经元细胞。 这种递送允许追踪神经元途径，此外，可以使用杆状病毒载体将治疗基因递送至否则不容易获得的靶神经元，用于治疗受试者中的神经元病症。

公开(公告)号：US20090016268A1

公开(公告)日：2009-01-15

申请号：US12118536

申请日：2008-05-09

Applicant: Byung K. Yi ,  Young C. Yoon ,  Li-Hsiang Sun ,  Shu Wang ,  Sang G. Kim

Inventor： Byung K. Yi ,  Young C. Yoon ,  Li-Hsiang Sun ,  Shu Wang ,  Sang G. Kim

IPC: H04Q7/00

CPC classification number: H04W56/001 ,  H04W92/20

Abstract: The present invention is related to controlling delay in a wireless communication system. The present invention includes receiving a signal from a plurality of base stations, measuring at least one signal delay of each of the plurality of base stations, reporting the measured at least one signal delay of each base station to a controller controlling the plurality of base stations, and receiving an adjusted signal from each of the plurality of base stations as a result of reporting the measured at least one signal delay, wherein each adjusted signal is received in a synchronous manner.

Abstract translation: 本发明涉及无线通信系统中的控制延迟。 本发明包括从多个基站接收信号，测量多个基站中的每一个的至少一个信号延迟，将测量的每个基站的至少一个信号延迟报告给控制多个基站的控制器 并且作为报告所测量的至少一个信号延迟的结果，从所述多个基站中的每一个接收调整后的信号，其中以同步方式接收每个经调整的信号。

公开(公告)号：US20080318882A1

公开(公告)日：2008-12-25

申请号：US11795348

申请日：2005-01-20

Applicant: Shu Wang ,  Xu Wang

Inventor： Shu Wang ,  Xu Wang

IPC: A61K31/7052 ,  A61P25/00

CPC classification number: A61K48/0075 ,  A61K48/00 ,  C12N2799/025 ,  C12N2799/026 ,  C12N2830/008

Abstract: The invention provides for methods for delivering a nucleic acid into a peripheral neuron by identifying a target neuron in a dorsal root ganglion and intrathecally delivering a vector comprising the nucleic acid to the dorsal root ganglion neuron. The nucleic acid may encode a neurotrophic factor that may be used to treat a peripheral neuropathy or, in conjunction with a nerve guide conduit, to treat a transected peripheral nerve.

Abstract translation: 本发明提供了通过鉴定背根神经节中的目标神经元并将包含核酸的载体鞘内递送至背根神经节神经元来将核酸递送至周围神经元的方法。 核酸可以编码可用于治疗周围神经病变的神经营养因子，或与神经导管结合治疗横切的周围神经。

公开(公告)号：US07341847B2

公开(公告)日：2008-03-11

申请号：US10407009

申请日：2003-04-02

Applicant: Shu Wang ,  Beihui Liu ,  Xu Wang

Inventor： Shu Wang ,  Beihui Liu ,  Xu Wang

IPC: C12P12/00 ,  C07H21/04 ,  C12N15/00 ,  C12N5/00

CPC classification number: A61K48/0058 ,  C07H21/04 ,  C12N15/86 ,  C12N2750/14143

Abstract: The invention relates to a chimeric promoter construct useful for neuronal cell specific gene expression. The invention provides a recombinant nucleic acid molecule that comprises a neuronal cell specific promoter such as platelet-derived growth factor β-chain promoter, operably linked to a heterologous enhancer which enhances the transcriptional activity of the promoter, such as cytomegalovirus immediate early gene enhancer. The promoter construct according to the invention can increase and prolong gene expression in neuronal cells and may be advantageously used in gene therapy of neuronal disorders.

Abstract translation: 本发明涉及可用于神经细胞特异性基因表达的嵌合启动子构建体。 本发明提供了一种重组核酸分子，其包含神经元细胞特异性启动子，例如血小板衍生生长因子β-链启动子，可操作地连接到增强启动子如巨细胞病毒立即早期基因增强子的转录活性的异源增强子。 根据本发明的启动子构建体可以增加并延长神经元细胞中的基因表达，并可有利地用于神经元疾病的基因治疗。

公开(公告)号：US20080030407A1

公开(公告)日：2008-02-07

申请号：US11906691

申请日：2007-10-02

Applicant: Chen Hung ,  Hsien Tseng ,  Lung Tai ,  Shu Wang

Inventor： Chen Hung ,  Hsien Tseng ,  Lung Tai ,  Shu Wang

IPC: H01Q1/38

CPC classification number: H01Q9/42 ,  H01Q5/371 ,  H01Q5/40

Abstract: A multi-frequency antenna includes a first antenna (1) and a second antenna (2) both operating at wireless wide area network, a third antenna (3) and a fourth antenna (4) both operating at wireless local area network. The first antenna, the second antenna, the third antenna and the fourth antenna are integrally made from a metal sheet and have a common grounding portion (50). The first and the second antennas have a first connecting portion (12) on which a feeding point (120) is located, and the third and the fourth antenna have a second connecting portion (34) on which another feeding point (340) is located.

Abstract translation: 多频天线包括在无线广域网上操作的第一天线（1）和第二天线（2），在无线局域网上操作的第三天线（3）和第四天线（4）。 第一天线，第二天线，第三天线和第四天线由金属片一体制成并具有公共接地部分（50）。 第一和第二天线具有第一连接部分（12），馈电点（120）位于该第一连接部分上，第三和第四天线具有第二连接部分（34），另一个馈电点（340）位于该第二连接部分 。

公开(公告)号：US07309757B2

公开(公告)日：2007-12-18

申请号：US10601262

申请日：2003-06-20

Applicant: Ye Liu ,  Shu Wang ,  Chaobin He

Inventor： Ye Liu ,  Shu Wang ,  Chaobin He

IPC: C08G73/00 ,  C08G73/02

CPC classification number: C08G63/20 ,  A61K47/34 ,  A61K48/0041 ,  C08G63/56 ,  C08G63/6854 ,  C08G73/02

Abstract: Provided is a poly(amino ester) having a polymer backbone comprising at least one secondary amine linkage and at least one tertiary amine linkage in the polymer backbone. Poly(amino ester)s are prepared via the Michael addition of a bis(acrylate ester)monomer to a diamine monomer, wherein the diamine monomer has one primary amino group and one secondary amino group, and can be end-capped by reaction with a suitable reagent. The inventive poly(amino ester)s may be used as vectors for delivery of a bioactive agent, such as DNA, to a cell.

Abstract translation: 提供了具有聚合物主链的聚（氨基酯），其在聚合物主链中包含至少一个仲胺键和至少一个叔胺键。 聚（氨基酯）是通过双（丙烯酸酯）单体向二胺单体的迈克尔加成制备的，其中二胺单体具有一个伯氨基和一个仲氨基，并且可以通过与 合适的试剂。 本发明的聚（氨基酯）可以用作向细胞递送生物活性剂如DNA的载体。

公开(公告)号：US20070086537A1

公开(公告)日：2007-04-19

申请号：US11536561

申请日：2006-09-28

Applicant: Young Yoon ,  Sang Kim ,  Li-Hsiang Sun ,  Shu Wang

Inventor： Young Yoon ,  Sang Kim ,  Li-Hsiang Sun ,  Shu Wang

IPC: H04L23/02

CPC classification number: H04L1/0631 ,  H04B7/0871 ,  H04B7/2606 ,  H04L1/0025 ,  H04L1/0038 ,  H04L1/0039 ,  H04L2001/0093 ,  H04W72/121 ,  H04W76/40 ,  H04W84/042 ,  H04W88/04

Abstract: A method of identifying a space-time encoded signal in a wireless communication system having at least two different decoder types is disclosed. The method includes receiving at least one pilot signal from a transmitting end, wherein the pilot signal is represented by either Type 0 or Type 1, determining which of Type 0 or Type 1 is represented in the received pilot signal, and activating the space-time decoder for performing space-time decoding, if the pilot signal is Type 1.

Abstract translation: 公开了一种在具有至少两种不同解码器类型的无线通信系统中识别时空编码信号的方法。 该方法包括从发送端接收至少一个导频信号，其中导频信号由类型0或类型1表示，确定在接收到的导频信号中表示类型0或类型1中的哪一个，并激活时空 解码器，用于执行空时解码，如果导频信号是类型1。

公开(公告)号：US20070086405A1

公开(公告)日：2007-04-19

申请号：US11536519

申请日：2006-09-28

Applicant: Shu Wang

Inventor： Shu Wang

IPC: H04B7/216

CPC classification number: H04B1/7105 ,  H04B1/712 ,  H04B2201/70701 ,  H04B2201/709727 ,  H04J13/00 ,  H04L25/022 ,  H04L25/0226

Abstract: A method of transmitting at least one packet in a wireless mobile communication system is disclosed. More specifically, the method includes transmitting at least one pilot symbol, at least one data symbol, and at least one null symbol, wherein the at least one null symbol is transmitted between transmission of the pilot symbol and the data symbol.

Abstract translation: 公开了一种在无线移动通信系统中发送至少一个分组的方法。 更具体地，该方法包括发送至少一个导频符号，至少一个数据符号和至少一个空符号，其中在导频符号的传输和数据符号之间传送至少一个空符号。

公开(公告)号：US20070072550A1

公开(公告)日：2007-03-29

申请号：US11536500

申请日：2006-09-28

Applicant: Shu Wang

Inventor： Shu Wang

IPC: H04B1/00 ,  H04B15/00

CPC classification number: H04B1/7105 ,  H04B1/712 ,  H04B2201/70701 ,  H04B2201/709727 ,  H04J13/00 ,  H04L25/022 ,  H04L25/0226

Abstract: A method of mitigating interference in a multiple access interference wireless communication system is disclosed. More specifically, the method comprises receiving at least one signal from at least one transmitting end, constructing a group of first signal signatures based on a predetermined number of received signals and at least one second signal signature, estimating a set of values using the constructed group of first signal signatures, and detecting desired information using the detected set of values.

Abstract translation: 公开了一种减轻多址干扰无线通信系统中的干扰的方法。 更具体地，该方法包括从至少一个发送端接收至少一个信号，基于预定数量的接收信号和至少一个第二信号签名来构建一组第一信号签名，使用所构造的组估计一组值 的第一信号签名，并且使用所检测的值集合来检测期望信息。

公开(公告)号：US20060181715A1

公开(公告)日：2006-08-17

申请号：US11388316

申请日：2006-03-24

Applicant: Thomas Bristow ,  Shu Wang ,  John Stephan

Inventor： Thomas Bristow ,  Shu Wang ,  John Stephan

IPC: G01B11/28

CPC classification number: G01B11/06

Abstract: A system for non-contact measurement of thickness of a test object. A laser beam is split into two identical directly opposed input beams. A calibration object of known thickness causes beams to be reflected from sides of the test object. Each reflected beam passes through sensing means including a pinhole aperture and a photodiode sensor. Maximum sensor output defines first and second focal points a known distance apart. The calibration object is removed, and the test object is inserted into the path of the input beams, creating focus position intensity curves for the reflected beams. By determining the deviation, at maximum photodiode output, of the positions of the test object reflecting surfaces from the positions of the calibration object surfaces, the test object thickness can be readily and accurately determined.

Abstract translation: 用于非接触测量测试对象厚度的系统。 激光束被分成两个相同的直接相对的输入光束。 已知厚度的校准对象使得光束从测试对象的侧面反射。 每个反射光束通过包括针孔孔和光电二极管传感器的感测装置。 最大传感器输出定义了已知距离的第一和第二焦点。 移除校准对象，将测试对象插入到输入光束的路径中，为反射光束创建焦点位置强度曲线。 通过从校准物体表面的位置确定测试对象反射表面的位置的最大光电二极管输出的偏差，可以容易且准确地确定测试对象厚度。