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    Method for Producing Radioactively Labeled Polypeptide
    71.
    发明申请
    Method for Producing Radioactively Labeled Polypeptide 审中-公开
    生产放射性标记多肽的方法

    公开(公告)号：US20130052132A1

    公开(公告)日：2013-02-28

    申请号：US13369903

    申请日：2012-02-09

    申请人： Hideo Saji ,  Nobuya Inagaki ,  Hiroyuki Kimura ,  Kentaro Toyoda ,  Konomu Hirao ,  Hirokazu Matsuda

    发明人： Hideo Saji ,  Nobuya Inagaki ,  Hiroyuki Kimura ,  Kentaro Toyoda ,  Konomu Hirao ,  Hirokazu Matsuda

    IPC分类号： C07K14/00 ,  A61K51/08

    CPC分类号： C07K14/57563 ,  A61K51/088 ,  C07K1/13

    摘要： The present invention relates to a method for producing a polypeptide. The method includes labeling a molecular probe precursor represented by an amino acid sequence of the formula (1) using a labeling compound capable of labeling a lysine or lysine derivative: (1) Y1-Leu-Ser-Xaa12-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg- Leu-Phe-Ile-Glu-Trp-Leu-Xaa27-Asn-Gly-Y2 where Y1 represents an amino acid sequence represented by the formula (2) or the amino acid sequence represented by the formula (2) with 1 to 8 amino acids from the N-terminus being deleted, Xaa12 represents a lysine or lysine derivative, Xaa27 represents a basic amino acid having no functional group at its side chain that reacts with the labeling compound or represents methyl lysine or acetylated lysine, and Y2 represents an amino acid sequence represented by the formula (3) or the amino acid sequence represented by the formula (3) with 1 to 9 amino acids from the C-terminus being deleted: (2) His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp (3) Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser

    摘要翻译： 本发明涉及一种生产多肽的方法。 该方法包括使用能够标记赖氨酸或赖氨酸衍生物的标记化合物来标记由式（1）的氨基酸序列表示的分子探针前体：（1）Y1-Leu-Ser-Xaa12-Gln-Met-Glu- Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Xaa27-Asn-Gly-Y2，其中Y1表示由式（2）表示的氨基酸序列或由 缺失N末端1〜8个氨基酸的式（2），Xaa12表示赖氨酸或赖氨酸衍生物，Xaa27表示其侧链上没有与标记化合物反应的官能团的碱性氨基酸， 赖氨酸或乙酰化赖氨酸，Y2表示由式（3）表示的氨基酸序列或由式（3）表示的氨基酸序列，其中C末端具有1至9个氨基酸缺失：（2）His- Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp（3）Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro

    Liquid crystal display device
    72.
    发明授权
    Liquid crystal display device 有权
    液晶显示装置

    公开(公告)号：US08350976B2

    公开(公告)日：2013-01-08

    申请号：US12538187

    申请日：2009-08-10

    申请人： Kazuyuki Harada ,  Hiroyuki Kimura

    发明人： Kazuyuki Harada ,  Hiroyuki Kimura

    IPC分类号： G02F1/1333

    CPC分类号： G02F1/1393 ,  G02F1/133707 ,  G02F1/136204 ,  G02F2001/13629

    摘要： A liquid crystal display device includes an array substrate, a counter substrate and a liquid crystal layer having liquid crystal molecules interposed therebetween. The liquid crystal molecules are aligned in a direction normal to a surface of the substrates under a condition where no electrical voltage is supplied between a picture electrode and a counter electrode. An alignment control device is provided at the counter substrate and configured to control the alignment of the liquid crystal molecules under a condition where an electric field is applied between the picture electrode and the counter electrode. A scanning line crossing a pixel is divided into first and second segments. The array substrate includes a connecting element to connect the first and second segments opposite the alignment control device.

    摘要翻译： 液晶显示装置包括阵列基板，对置基板和夹在其间的液晶分子的液晶层。 在图像电极和对电极之间没有电压供给的条件下，液晶分子在垂直于基板的表面的方向上排列。 对准控制装置设置在对置基板上，并被配置为在图像电极和对电极之间施加电场的条件下控制液晶分子的对准。 穿过像素的扫描线被划分成第一和第二段。 阵列基板包括连接元件以连接与对准控制装置相对的第一和第二部分。

    VIDEO GAME SYSTEMS AND METHODS
    73.
    发明申请
    VIDEO GAME SYSTEMS AND METHODS 有权
    视频游戏系统和方法

    公开(公告)号：US20130005462A1

    公开(公告)日：2013-01-03

    申请号：US13610066

    申请日：2012-09-11

    申请人： Shigeru MIYAMOTO ,  Hiroyuki Kimura ,  Shigeyuki Asuke

    发明人： Shigeru MIYAMOTO ,  Hiroyuki Kimura ,  Shigeyuki Asuke

    IPC分类号： A63F13/06

    CPC分类号： A63F13/56 ,  A63F13/10 ,  A63F13/20 ,  A63F13/21 ,  A63F13/235 ,  A63F13/25 ,  A63F13/327 ,  A63F13/45 ,  A63F13/58 ,  A63F13/822 ,  A63F13/843 ,  A63F2300/65 ,  A63F2300/8088

    摘要： Example systems and methods relate to a video game in which multiple players each supply inputs to a respective input device to control a corresponding game character in a game world. Movements and actions of each game character are controlled in accordance with a first game character control operation during the playing of the video game. If one or more conditions is satisfied by one of the players, the one player's game character is protected from harm in the game world. Movements and actions of the protected game character are controlled in accordance with a second game character control operation. The protecting of the one player's game character is stopped in response to one or more protecting stopping conditions, whereby the game character is again controllable in accordance with the first game character control operation. If all game characters are protected, current playing of the video game ends.

    摘要翻译： 示例系统和方法涉及一种视频游戏，其中多个玩家每个向相应的输入设备提供输入以控制游戏世界中相应的游戏角色。 根据在游戏过程中的第一游戏角色控制操作来控制每个游戏角色的动作和动作。 如果其中一个玩家满足一个或多个条件，则玩家的游戏角色将被保护免受游戏世界的伤害。 根据第二游戏角色控制操作来控制受保护的游戏角色的移动和动作。 响应于一个或多个保护停止条件停止一个玩家的游戏角色的保护，由此根据第一游戏角色控制操作再次控制游戏角色。 如果所有游戏角色受到保护，则视频游戏的当前播放结束。

    LIQUID CRYSTAL DISPLAY DEVICE
    75.
    发明申请
    LIQUID CRYSTAL DISPLAY DEVICE 有权
    液晶显示装置

    公开(公告)号：US20120229745A1

    公开(公告)日：2012-09-13

    申请号：US13371798

    申请日：2012-02-13

    申请人： Kazuyuki Harada ,  Hiroyuki Kimura ,  Junichi Kobayashi ,  Masato Nakamura

    发明人： Kazuyuki Harada ,  Hiroyuki Kimura ,  Junichi Kobayashi ,  Masato Nakamura

    IPC分类号： G02F1/1337

    CPC分类号： G02F1/133784 ,  G02F1/133707 ,  G02F1/134309 ,  G02F2001/134372

    摘要： In one embodiment, a liquid crystal display device includes a first substrate and a second substrate. The first substrate includes a switching element, a first electrode, a second electrode electrically connected with the switching element and facing the first electrode. In the second electrode, a plurality of slits in a V shape is formed along a first direction. The first and second substrates include first and second alignment films, respectively. The slit in the V shape includes a central portion, a first end connected with one end of the first central portion, a second end connected with the other end of the first central portion, a second central portion, a third end connected with one end of the second central portion, and a fourth end connected with the other end of the second central portion. The first end and the third end are connected each other.

    摘要翻译： 在一个实施例中，液晶显示装置包括第一基板和第二基板。 第一基板包括开关元件，第一电极，与开关元件电连接并面向第一电极的第二电极。 在第二电极中，沿着第一方向形成有V形的多个狭缝。 第一和第二基板分别包括第一和第二取向膜。 V形的狭缝包括中心部分，与第一中心部分的一端连接的第一端，与第一中心部分的另一端连接的第二端，第二中心部分，与一端连接的第三端 并且与第二中心部分的另一端连接的第四端。 第一端和第三端彼此连接。

    Method and apparatus for data reproduction
    77.
    发明授权
    Method and apparatus for data reproduction 有权
    用于数据再现的方法和装置

    公开(公告)号：US08165453B2

    公开(公告)日：2012-04-24

    申请号：US11899648

    申请日：2007-09-06

    申请人： Akio Fukushima ,  Hiroyuki Kimura ,  Hiroo Okamoto

    发明人： Akio Fukushima ,  Hiroyuki Kimura ,  Hiroo Okamoto

    IPC分类号： H04N9/80

    CPC分类号： H04N9/8042 ,  H04N5/85 ,  H04N5/913 ,  H04N2005/91335

    摘要： A data reproduction method and apparatus includes first circuitry to produce an information signal from a storage medium. The information signal includes copy control information. Detection circuitry is provided to detect the copy control information. Control circuitry is provided to operate the first circuitry to selectively output the information signal based on the detection result of the detection circuitry.

    摘要翻译： 数据再现方法和装置包括从存储介质产生信息信号的第一电路。 信息信号包括复制控制信息。 提供检测电路以检测复制控制信息。 提供控制电路以操作第一电路以基于检测电路的检测结果选择性地输出信息信号。

    Differential amplifier with offset voltage trimming
    79.
    发明授权
    Differential amplifier with offset voltage trimming 有权
    差分放大器，具有失调电压调整

    公开(公告)号：US07956679B2

    公开(公告)日：2011-06-07

    申请号：US12511076

    申请日：2009-07-29

    申请人： Hiroyuki Kimura

    发明人： Hiroyuki Kimura

    IPC分类号： H03F1/02

    CPC分类号： H03F3/45179 ,  H03F3/45206 ,  H03F3/45632 ,  H03F2200/375 ,  H03F2203/45482 ,  H03F2203/45492 ,  H03F2203/45494

    摘要： A differential amplifier that has a current supply and a differential current to voltage converter with a positive current input node, a negative current input node and a voltage output node, has offset voltage trimming. The voltage output node provides an output voltage that is proportional to the difference in current values flowing into the positive current input node and a negative current input node. A trimming circuit has a plurality of trimming control inputs, an inverting trimming output, a non-inverting trimming output and trimming inputs coupled to the current supply. Trimming resistances couple the inverting trimming output to the non-inverting trimming output. Trimming selectors, controllable by a trim code provided to the trimming control inputs, provide for selectively connecting the current supply directly to the non-inverting trimming output while selectively connecting the current supply to the inverting trimming output through a first selected group of the trimming resistances. The differential amplifier also has a differential transistor pair formed by an inverting transistor that couples the inverting trimming output to the positive current input node and a non-inverting transistor that couples the non-inverting trimming output to the negative current input node.

    摘要翻译： 具有电流源的差分放大器和具有正电流输入节点，负电流输入节点和电压输出节点的差分电流至电压转换器具有偏移电压调整。 电压输出节点提供与流入正电流输入节点和负电流输入节点的电流值的差成比例的输出电压。 修整电路具有多个微调控制输入，反相微调输出，非反相微调输出和耦合到电流源的微调输入。 微调电阻将反相微调输出耦合到非反相微调输出。 可通过提供给微调控制输入的修剪代码控制的微调选择器提供选择性地将电流源直接连接到非反相微调输出，同时通过第一选定组的微调电阻选择性地将电流供给到反相微调输出 。 差分放大器还具有由反相晶体管形成的差分晶体管对，其将反相微调输出耦合到正电流输入节点，以及将非反相微调输出耦合到负电流输入节点的非反相晶体管。