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公开(公告)号：US08821429B2
公开(公告)日：2014-09-02
申请号：US12568899
申请日：2009-09-29
申请人： Jaime Vargas
发明人： Jaime Vargas
CPC分类号： A61F5/0076 , A61B17/12099 , A61B17/12136 , A61F5/0003 , A61F5/0013 , A61F5/003 , A61F5/0036 , A61F5/0073 , A61F5/0079 , A61F2002/045 , A61M25/04 , A61M2210/1042 , A61M2210/1053 , A61M2210/1057 , A61M2210/106
摘要： An intragastric implant comprises an anchor and a therapeutic device or a diagnostic device. The anchor is adapted to extend between the fundus and the pyloric valve of a stomach, to be retained without attachment to the stomach wall, and to anchor the device within the stomach with a relatively stable position and orientation. The therapeutic or diagnostic device is adapted to extend from the esophagus or stomach to the intestines or stomach. The therapeutic or diagnostic device, when extending into the esophagus, will be slidably received through the gastroesophageal junction and, when extending into the intestines, will be slidably received in the pyloric valve.
摘要翻译： 胃内植入物包括锚和治疗装置或诊断装置。 锚固件适于在胃的胃底部和幽门阀之间延伸，以保持而不附着到胃壁，并且以相对稳定的位置和取向将装置锚定在胃内。 治疗或诊断装置适于从食道或胃延伸到肠或胃。 治疗或诊断装置在延伸进入食管时将通过胃食管接合部被可滑动地容纳，并且当延伸进入肠道时，可滑动地容纳在幽门阀中。
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72.发明授权公开(公告)号：US08801647B2
公开(公告)日：2014-08-12
申请号：US12070912
申请日：2008-02-21
CPC分类号： A61F5/0076 , A61F2/04 , A61F5/0013 , A61F5/0079 , A61F5/0083 , A61F2002/044
摘要： Method for treating a Roux-en-Y patient having fistulas and leaks as a result of bariatric surgery. A gastrointestinal implant device is anchored in the esophagus and extends through a stomach pouch into an intestine anastomosed to the stomach pouch to prevent fistulas and other damaged tissue from making contact with food and fluids entering the esophagus. The gastrointestinal implant device includes an unsupported flexible sleeve and an anchor coupled to a proximal portion of the sleeve. The flexible sleeve is open at both ends, and adapted to extend below a jejunum. The anchor is adapted to be retained within the esophagus, preferably just above the gastroesophageal (GE) Junction. The anchor can include a stent such as a wave anchor and is collapsible for catheter-based delivery and removal.
摘要翻译： 通过减肥手术治疗患有瘘和泄漏的Roux-en-Y患者的方法。 胃肠道植入装置被锚定在食道中并且延伸穿过胃袋进入吻合到胃袋的肠，以防止瘘和其它受损组织与进入食道的食物和液体接触。 胃肠道植入装置包括未支撑的柔性套管和联接到套筒的近端部分的锚固件。 柔性套管在两端敞开，适于在空肠下方延伸。 该锚适于保留在食道内，优选位于胃食管（GE）结点之上。 锚固件可以包括诸如波浪锚的支架，并且可折叠以用于基于导管的输送和移除。
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公开(公告)号：US20140221900A1
公开(公告)日：2014-08-07
申请号：US14167351
申请日：2014-01-29
申请人： Christy Cummins , James E. Coleman
发明人： James E. Coleman , Christy Cummins
CPC分类号： A61M27/002 , A61B17/11 , A61B17/1114 , A61B2017/00243 , A61B2017/00986 , A61B2017/0419 , A61B2017/1139 , A61F2/064 , A61F2/2445 , A61F2/2493 , A61F5/0076 , A61F2002/045
摘要： Methods and devices for treating obesity are provided, and more particularly, methods and devices for performing gastric bypasses are disclosed. In one exemplary embodiment a gastric bypass procedure is provided that includes forming a gastro-entero anastomosis between a stomach and an intestine and forming an entero-entero anastomosis between a portion of the intestine distal to the gastro-entero anastomosis and a portion of the intestine proximal to the gastro-entero anastomosis. A surrogate path is formed between the esophagus and the gastro-entero anastomosis to at least partially direct fluid from the esophagus to the intestine by way of the gastro-entero anastomosis, thereby bypassing the stomach. A variety of devices that are particularly useful in gastric bypass procedures are also disclosed. The devices include anastomotic devices that can be coupled to or integrally formed with a shunt. The devices can include a plurality of tubular bodies that are configured to have an adjustable length. Still further, methods for repairing an abdominal aortic aneurysm and leaking heart valve are also disclosed.
摘要翻译： 提供了用于治疗肥胖症的方法和装置，更具体地，公开了用于进行胃旁路的方法和装置。 在一个示例性实施例中，提供了胃旁路手术，其包括在胃和肠之间形成胃肠吻合并且在远离胃肠吻合的肠的一部分和肠的一部分之间形成肠肠吻合 靠近胃肠吻合。 在食道和胃肠吻合之间形成替代路径，以通过胃肠吻合至少部分地将流体从食道引导到肠，从而绕过胃。 还公开了在胃旁路手术中特别有用的各种装置。 这些装置包括能够与分路耦合或一体形成的吻合装置。 这些装置可以包括被配置为具有可调节长度的多个管状体。 此外，还公开了修复腹主动脉瘤和泄漏心脏瓣膜的方法。
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公开(公告)号：US20140180192A1
公开(公告)日：2014-06-26
申请号：US14239899
申请日：2012-08-23
IPC分类号： A61F5/00
CPC分类号： A61F5/0076 , A61F5/0089
摘要： Endoluminal sleeve device (1) for internally lining a section of the GI tract, comprising a sleeve (2) configured for deployment inside a GI tract, the sleeve (2) having walls of a flexible material defining a sleeve lumen (3), a proximal end (4) defining a proximal lumen opening (5), and a distal end (6) defining a distal lumen opening (7), a tubular anchoring portion (8) forming said proximal lumen end (4) and defining anchoring seats (9) delimited each one by an annular collar (11) forming an opening through which adjacent tissue portions (12) can be pulled into the anchoring seats (9), expansion means adapted to act on the tissue portions (12) arranged in the anchoring seats (9) such that the tissue portions (12) expand to a dimension greater than the opening of the annular collar (11).
摘要翻译： 用于内部衬里胃肠道部分的内腔套管装置（1），包括构造成用于部署在胃肠道内的套筒（2），所述套管（2）具有限定套管内腔（3）的柔性材料的壁， 限定近端腔开口（5）的近端（4）和限定远端内腔开口（7）的远端（6），形成所述近端内腔端部（4）的管状锚固部分（8） 9）通过形成开口的环形套环（11）限定，相邻组织部分（12）可以通过该开口被拉入锚固座（9），适于作用在布置在锚固中的组织部分（12）上的膨胀装置 座（9），使得组织部分（12）膨胀成大于环形套环（11）的开口的尺寸。
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公开(公告)号：US20140081416A1
公开(公告)日：2014-03-20
申请号：US14084073
申请日：2013-11-19
发明人： Claude O. Clerc , Kurt Geitz
IPC分类号： A61F2/90
CPC分类号： A61F2/90 , A61F2/848 , A61F5/0076 , A61F2002/045 , A61F2002/828 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2250/0039
摘要： In at least one embodiment, the invention is directed to an endoluminal device comprising a stent and a sleeve. In one embodiment, the endoluminal device is implanted in a portion of the gastrointestinal tract. In some embodiments, the stent has a first region and a second region where the first and second regions provide different levels of radial force. In one embodiment, the first region is made from a plurality of first wires having a first diameter and the second region is made from a plurality of second wires having a second diameter which is smaller than the first diameter. In other embodiments, the endoluminal device has at least one engagement mechanism engaging the stent to the sleeve, the endoluminal device to a body lumen, and any combination thereof. In at least one embodiment, the endoluminal device has a wall with at least one opening therein.
摘要翻译： 在至少一个实施例中，本发明涉及一种包括支架和套管的腔内装置。 在一个实施例中，腔内装置植入胃肠道的一部分。 在一些实施例中，支架具有第一区域和第二区域，其中第一和第二区域提供不同水平的径向力。 在一个实施例中，第一区域由具有第一直径的多个第一布线制成，并且第二区域由具有小于第一直径的第二直径的多个第二布线制成。 在其它实施例中，腔内装置具有至少一个接合机构，其将支架接合到套筒，腔内装置到体腔及其任何组合。 在至少一个实施例中，腔内装置具有其中具有至少一个开口的壁。
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公开(公告)号：US08672958B2
公开(公告)日：2014-03-18
申请号：US13491133
申请日：2012-06-07
申请人： James E. Coleman , Christy Cummins
发明人： James E. Coleman , Christy Cummins
IPC分类号： A61B17/08
CPC分类号： A61M27/002 , A61B17/11 , A61B17/1114 , A61B2017/00243 , A61B2017/00986 , A61B2017/0419 , A61B2017/1139 , A61F2/064 , A61F2/2445 , A61F2/2493 , A61F5/0076 , A61F2002/045
摘要： Methods and devices for treating obesity are provided, and more particularly, methods and devices for performing gastric bypasses are disclosed. In one exemplary embodiment a gastric bypass procedure is provided that includes forming a gastro-entero anastomosis between a stomach and an intestine and forming an entero-entero anastomosis between a portion of the intestine distal to the gastro-entero anastomosis and a portion of the intestine proximal to the gastro-entero anastomosis. A surrogate path is formed between the esophagus and the gastro-entero anastomosis to at least partially direct fluid from the esophagus to the intestine by way of the gastro-entero anastomosis, thereby bypassing the stomach. Still further, methods for repairing an abdominal aortic aneurysm and leaking heart valve are also disclosed.
摘要翻译： 提供了用于治疗肥胖症的方法和装置，更具体地，公开了用于进行胃旁路的方法和装置。 在一个示例性实施例中，提供了胃旁路手术，其包括在胃和肠之间形成胃肠吻合并且在远离胃肠吻合的肠的一部分和肠的一部分之间形成肠肠吻合 靠近胃肠吻合。 在食道和胃肠吻合之间形成替代路径，以通过胃肠吻合至少部分地将流体从食道引导到肠，从而绕过胃。 此外，还公开了修复腹主动脉瘤和泄漏心脏瓣膜的方法。
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公开(公告)号：US08672831B2
公开(公告)日：2014-03-18
申请号：US13331425
申请日：2011-12-20
IPC分类号： A61F13/00
CPC分类号： A61F5/004 , A61F2/04 , A61F5/0003 , A61F5/0013 , A61F5/0036 , A61F5/0043 , A61F5/0069 , A61F5/0076 , A61F5/0089 , A61F2002/044 , A61F2002/045
摘要： A bariatric device and method of causing at least partial satiety includes a body having a wall defining a lumen. The wall is configured to generally conform to the shape and size of i) the abdominal portion of the esophagus and/or ii) the proximal cardiac portion of the stomach. The wall is adapted to exert a force on the i) abdominal portion of the esophagus and/or ii) the proximal cardiac portion of the stomach thereby influencing a neurohormonal feedback mechanism to cause at least partial satiety by augmenting fullness caused by food and simulating fullness in the absence of food. A fixation system is included to resist distal migration of the body. The fixation system includes at least a portion of the wall having a tissue ingrowth characteristic to promote ingrowth of tissue in the wall.
摘要翻译： 引起至少部分饱腹感的减肥装置和方法包括具有限定内腔的壁的主体。 该壁被构造成大致符合i）食道的腹部部分的形状和尺寸和/或ii）胃的近端心脏部分。 壁适应于i）食管的腹部部分和/或ii）胃的近端心脏部分，从而影响神经激素反馈机制，以通过增加由食物引起的丰满度和模拟丰满度来产生至少部分饱腹感 在没有食物的情况下。 包括固定系统以抵抗身体的远端迁移。 固定系统包括壁的至少一部分具有组织向内生长特征，以促进壁中组织的向内生长。
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公开(公告)号：US20140031738A1
公开(公告)日：2014-01-30
申请号：US14042654
申请日：2013-09-30
CPC分类号： A61M27/002 , A61F2/04 , A61F5/0076 , A61F2002/044
摘要： The present invention provides systems and methods for treating and controlling obesity and/or type II diabetes. In one aspect of the invention, a device comprises a hollow sleeve sized and shaped for positioning within a duodenum of the patient, an anchor coupled to the proximal end of the sleeve and being sized and shaped to inhibit distal migration of the sleeve and a plurality of elastomeric objects coupled to the distal end of the sleeve and being sized and shaped to inhibit proximal migration of the sleeve through a pylorus of the patient. The bypass device can be placed and removed endoscopically through the patient's esophagus in a minimally invasive outpatient procedure and it is “self-anchoring” and does not require invasive tissue fixation within the patient's GI tract, thereby reducing collateral tissue damage and minimizing its impact on the digestive process.
摘要翻译： 本发明提供用于治疗和控制肥胖症和/或II型糖尿病的系统和方法。 在本发明的一个方面，一种装置包括尺寸和形状适于定位在患者的十二指肠内的中空套筒，联接到套筒的近端的锚固件，其尺寸和形状被设计成阻止套筒的远端移动，并且多个 耦合到套筒的远端的弹性体物体的尺寸和形状以阻止套管穿过患者幽门的近端迁移。 旁路装置可以通过患者的食管在微创门诊手术中内窥镜放置和移除，并且它是“自我锚定”的，并且不需要在患者胃肠道内进行侵入性组织固定，从而减少侧支组织损伤并使其对 消化过程。
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公开(公告)号：US20140024991A1
公开(公告)日：2014-01-23
申请号：US13923928
申请日：2013-06-21
发明人： Albert K. Chin
IPC分类号： A61F5/00
CPC分类号： A61F5/0076 , A61F2/04 , A61F5/0089 , A61F2002/045
摘要： The present invention provides bariatric therapy systems. One system includes a gastrointestinal implant device and a delivery mechanism therefor. The device can include a sleeve for placement into a small intestine and to minimize absorption of nutrients by its walls. An anchoring mechanism coupled to a proximal end of the sleeve and designed to be secured within the stomach can be provided. A passageway extending through the anchoring mechanism and the sleeve can also be provided, along which food can be directed from the stomach to the small intestine. The delivery mechanism can include a housing for accommodating the device, and a deploying balloon situated within the housing and which can be actuated to direct the sleeve of the device from within the housing to the site of implantation. Methods for providing bariatric therapy are also provided by the present invention.
摘要翻译： 本发明提供了减肥治疗系统。 一个系统包括胃肠道植入装置及其输送机构。 该装置可以包括用于放置在小肠中的套筒并且最小化其壁部对营养物的吸收。 可以提供联接到套筒的近端并被设计成固定在胃中的锚定机构。 还可以设置延伸穿过锚固机构和套筒的通道，食物可以沿着该通道从胃引导到小肠。 输送机构可以包括用于容纳装置的壳体和位于壳体内的展开气囊，并且可以将其推动以将装置的套管从壳体引导到植入位置。 提供减肥治疗的方法也由本发明提供。
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公开(公告)号：US20130331642A1
公开(公告)日：2013-12-12
申请号：US13882274
申请日：2011-11-01
IPC分类号： A61F5/00
CPC分类号： A61F5/0063 , A61F5/003 , A61F5/0076
摘要： One aspect of the present invention includes a preformed gastric band comprising a flexible substrate and a plurality of band members. The flexible substrate comprises oppositely disposed first and second major surfaces defined by first and second minor side portions and first and second major side portions. The first major surface includes a lower collar section and an upper band section. The plurality of flexible band members is securely connected to the upper band section and extends between the first and second minor side portions of the substrate. Each of the band members includes first and second ends that comprise an attachment mechanism for connecting the first and second ends. Each of the band members is separated from one another by a spacing region.
摘要翻译： 本发明的一个方面包括预成形的胃带，其包括柔性基底和多个带状部件。 柔性基板包括由第一和第二副侧部分以及第一和第二主要侧部限定的相对设置的第一和第二主表面。 第一主表面包括下套环部分和上带部分。 多个柔性带构件牢固地连接到上带部分并且在基板的第一和第二次侧部分之间延伸。 每个带构件包括包括用于连接第一端和第二端的连接机构的第一端和第二端。 每个带状构件通过间隔区域彼此分离。
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