公开(公告)号：US09061990B2

公开(公告)日：2015-06-23

申请号：US14128899

申请日：2012-06-27

Applicant: YongQi Mu

Inventor： YongQi Mu

IPC: C07C69/63 ,  C07C67/307 ,  C07C51/363 ,  C07C51/62

CPC classification number: C07C51/36 ,  C07C51/363 ,  C07C51/50 ,  C07C51/62 ,  C07C51/64 ,  C07C67/03 ,  C07C67/22 ,  C07C67/307 ,  C07C67/62 ,  C07C253/30 ,  C07C253/32 ,  C07C69/63 ,  C07C53/21 ,  C07C53/50 ,  C07C255/03

Abstract: The present invention generally relates to processes for converting acrylate esters or a derivative thereof to difluoropropionic acid or a derivative thereof. This process is generally performed using fluorine gas in a hydrofluorocarbon solvent.

Abstract translation: 本发明一般涉及将丙烯酸酯或其衍生物转化为二氟丙酸或其衍生物的方法。 该方法通常在氢氟烃溶剂中使用氟气进行。

公开(公告)号：US20150148560A1

公开(公告)日：2015-05-28

申请号：US14404384

申请日：2013-05-31

Applicant: MICROMIDAS, INC.

Inventor： Ryan L. Smith ,  John Bissell ,  Makoto N. Masuno ,  Douglas Cannon ,  Alex B. Wood ,  Marc Foster

IPC: C07C67/31 ,  C07C1/24 ,  C07C51/16 ,  C07C67/03 ,  C07C29/09

CPC classification number: C07C67/31 ,  C07C1/24 ,  C07C29/095 ,  C07C29/149 ,  C07C51/16 ,  C07C67/03 ,  C07C67/30 ,  C07C2527/167 ,  C07C69/675 ,  C07C69/533 ,  C07C11/167 ,  C07C57/15 ,  C07C69/56 ,  C07C31/207

Abstract: Provided herein are methods that utilize polyhydroxyalkanoates (PHAs) as a substrate for further conversion to C4 and C5 compounds. Polyhydroxyalkanoates can undergo esterification to yield alkyl hydroxyalkanoates and alkyl alkenoates, which may serve as useful precursors in the production of alkadienes and alkenedioic acids, including for example butadiene and butenedioic acid.

Abstract translation: 本文提供了利用聚羟基链烷酸酯（PHA）作为底物进一步转化成C4和C5化合物的方法。 聚羟基链烷酸酯可以进行酯化以得到烷基羟基链烷酸酯和烷基链烯酸酯，其可用作生产烷二烯和烯二酸的有用前体，包括例如丁二烯和丁烯二酸。

公开(公告)号：US20150126766A1

公开(公告)日：2015-05-07

申请号：US14516979

申请日：2014-10-17

Applicant: OSAKA ORGANIC CHEMICAL INDUSTRY LTD.

Inventor： Yukio Tanaka ,  Kohei Okamura ,  Toyoyuki Sugiura ,  Keisuke Ito ,  Naohiko Kawakami ,  Shigeaki Matsumoto ,  Masayoshi Matsuno

IPC: C07C67/40

CPC classification number: C07C67/40 ,  C07C67/03 ,  C07C69/54

Abstract: A process for preparing 4-hydroxybutyl acrylate by transesterifying an alkyl acrylate with 1,4-butanediol in the presence of a dialkyltin oxide such that each of the alkyl groups has 4 to 8 carbon atoms, characterized in that the amount of the dialkyltin oxide is adjusted to 0.00001 to 0.01 moles per one mole of the alkyl acrylate.

Abstract translation: 一种通过在二烷基锡氧化物的存在下，用丙烯酸烷基酯与1,4-丁二醇进行酯交换使得每个烷基具有4至8个碳原子来制备丙烯酸4-羟基丁酯的方法，其特征在于二烷基氧化锡的量为 相对于每摩尔丙烯酸烷基酯调整为0.00001〜0.01摩尔。

公开(公告)号：US20150111264A1

公开(公告)日：2015-04-23

申请号：US14396990

申请日：2013-04-26

Applicant: Kao Corporation

Inventor： Tatsuro Ozaki ,  Yasushi Takimura

IPC: C12P7/64 ,  C07C67/08

CPC classification number: C12P7/6409 ,  C07C51/09 ,  C07C67/03 ,  C07C67/08 ,  C11B1/00 ,  C12N1/12 ,  C12P7/6463 ,  C07C69/24 ,  C07C53/126

Abstract: Provided is a method for producing a lipid, by which lipid including a high ratio of medium-chain fatty acids can be produced efficiently.Disclosed is a method for producing a lipid, the method comprising the following steps (1) and (2): (1) a step of culturing algae of the class Dinophyceae in a medium containing glycerin to obtain a culture; and (2) a step of collecting a lipid from a culture thus obtained.

Abstract translation: 本发明提供一种脂质的制造方法，能够高效率地制造包含高比例的中链脂肪酸的脂质。 公开了一种生产脂质的方法，该方法包括以下步骤（1）和（2）：（1）在含有甘油的培养基中培养Dinophyceae类藻类以获得培养物的步骤; 和（2）从由此获得的培养物中收集脂质的步骤。

公开(公告)号：US20150018573A1

公开(公告)日：2015-01-15

申请号：US13987228

申请日：2013-07-13

Applicant: Zackery Allen McMurry ,  James Casey Smoot

Inventor： Zackery Allen McMurry ,  James Casey Smoot

IPC: C07C67/02

CPC classification number: C07C67/31 ,  C07C67/03 ,  C07C69/56 ,  C07C69/708

Abstract: The present invention describes a method for production of a class of renewable specialty chemicals that may be used for a variety of purposes including as a solvent in the semiconductor industry and as a reagent for commercial chemical production. The precursor compound, PHA, can be produced using various feedstocks such as waste water treatment plant biosolids, distiller's grains and agricultural residual biomass (e.g., corn stover and rice straw). The production of specialty chemicals in tandem with energy production can serve to aid the overall economics of renewable feedstock energy production.

Abstract translation: 本发明描述了可用于各种目的的可再生特种化学品的生产方法，包括作为半导体工业中的溶剂和作为商业化学品生产的试剂。 可以使用各种原料如废水处理厂生物固体，蒸馏谷物和农业残留生物量（例如玉米秸秆和稻草）来生产前体化合物PHA。 与能源生产一起生产特种化学品可以帮助可再生原料能源生产的整体经济。

公开(公告)号：US20140371451A1

公开(公告)日：2014-12-18

申请号：US14471682

申请日：2014-08-28

Applicant: Lonza Ltd

Inventor： Christian Noti ,  Guixian Hu ,  Barry Jackson

IPC: C07D319/06 ,  C07D207/34 ,  C07C67/297 ,  C07D239/42

CPC classification number: C07D319/06 ,  C07C67/03 ,  C07C67/05 ,  C07C67/297 ,  C07C67/32 ,  C07D207/34 ,  C07D239/42 ,  C07C69/716

Abstract: The invention discloses a method for the preparation of tert-butyl 6-chloro-3,5-dioxohexanoate from Meldrum's acid derivative and its use for the preparation of tert-butyl (4R,6S)-(6-hydroxymethyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate (BHA), Rosuvastatin and Atorvastatin.

Abstract translation: 本发明公开了一种从Meldrum酸衍生物制备6-氯-3,5-二氧代己酸叔丁酯的方法及其用于制备（4R，6S） - （6-羟甲基-2,2-二甲基 - 二甲基-1,3-二恶烷-4-基）乙酸酯（BHA），罗苏伐他汀和阿托伐他汀。

公开(公告)号：US20140364643A1

公开(公告)日：2014-12-11

申请号：US14467326

申请日：2014-08-25

Applicant: Cargill, Incorporated

Inventor： Paraskevas Tsobanakis ,  Xiangsheng Meng ,  Timothy Walter Abraham

IPC: C07C67/30 ,  C07C51/347

CPC classification number: C07C67/30 ,  C07C51/347 ,  C07C51/377 ,  C07C67/03 ,  C07C67/08 ,  C07C67/31 ,  C07C67/327 ,  C12P7/42 ,  C12P7/52 ,  C07C57/04 ,  C07C69/675 ,  C07C69/708 ,  C07C69/54

Abstract: Preparation of derivatives of β-hydroxycarboxylic acid, including β-hydroxycarboxylic acid esters, α,β-unsaturated carboxylic acids, esters of α,β-unsaturated carboxylic acid, and alkoxy derivatives.

Abstract translation: 包含β-羟基羧酸酯，α，β-不饱和羧酸，α，β-不饱和羧酸酯和烷氧基衍生物的β-羟基羧酸衍生物的制备。

公开(公告)号：US20140363348A1

公开(公告)日：2014-12-11

申请号：US14357145

申请日：2012-11-09

Applicant: Microwave Chemical Co., Ltd. ,  CHEMICAL REACTION APPARATUS ,  OSAKA UNIVERSITY

Inventor： Akinori Ishizuka ,  Iwao Yoshino ,  Kunitaka Momota ,  Yasunori Tsukahara

IPC: B01J19/12

CPC classification number: B01J19/24 ,  B01J8/20 ,  B01J8/36 ,  B01J19/126 ,  B01J19/18 ,  B01J19/1862 ,  B01J2208/00442 ,  B01J2208/00867 ,  B01J2219/00141 ,  B01J2219/1215 ,  B01J2219/1218 ,  B01J2219/1245 ,  B01J2219/1266 ,  B01J2219/1269 ,  B01J2219/1293 ,  B01J2219/1296 ,  B01J2219/182 ,  B01J2219/187 ,  C07C67/03 ,  C07C67/08 ,  H05B6/78 ,  H05B6/806 ,  C07C69/52

Abstract: A chemical reaction apparatus includes: a horizontal flow-type reactor inside of which has been partitioned into multiple chambers by multiple partition plates, and a liquid content horizontally flows with an unfilled space being provided thereabove; a microwave generator that generates microwaves; and at least one waveguide that transmits the microwaves generated by the microwave generator to the unfilled space in the reactor. The content flows over each of the partition plates, and, in each chamber, a weir height on an inlet side is higher than a weir height on an outlet side by at least an overflow depth at the partition plate on the outlet side.

Abstract translation: 化学反应装置包括：水平流式反应器，其内部通过多个隔板被分隔成多个室，并且液体内容物水平地流动，在其上方设置有未填充的空间; 产生微波的微波发生器; 以及将由微波发生器产生的微波传输到反应器中的未填充空间的至少一个波导。 内容物流过每个隔板，并且在每个室中，入口侧的堰高度高于出口侧的堰高度至少在出口侧的隔板处的溢流深度。

公开(公告)号：US08907113B2

公开(公告)日：2014-12-09

申请号：US13539454

申请日：2012-07-01

Applicant: Aicardo Roa-Espinosa ,  Hailin Lin

Inventor： Aicardo Roa-Espinosa ,  Hailin Lin

IPC: C11C3/00 ,  C07C67/03 ,  C11C3/04 ,  C07C67/02 ,  C11C1/10 ,  C07C29/76 ,  C11B3/00 ,  C11B3/06

CPC classification number: C07C67/03 ,  C07C29/76 ,  C07C67/02 ,  C11B3/001 ,  C11B3/06 ,  C11C1/10 ,  C11C3/003 ,  C11C3/04 ,  Y02E50/13 ,  C07C69/52 ,  C07C31/225

Abstract: A process for separating glycerin from methyl ester at an enhanced rate is disclosed. The improved process results from carrying out the transesterification reaction in a substantially non-polar and water free environment. A polymer selected from a group of polymers shown to be effective in such an environment is added to the product mixture which greatly improves the rate of separation between the methyl ester and the glycerin and reduces the number of required steps to accomplish the separation.

Abstract translation: 公开了以增强的速率从甲酯中分离甘油的方法。 改进的方法是在基本上非极性和无水环境中进行酯交换反应。 选自显示在这种环境中有效的一组聚合物的聚合物被加入到产品混合物中，这大大提高了甲酯与甘油之间的分离速度，并减少了完成分离所需的步骤数量。

公开(公告)号：US08884078B1

公开(公告)日：2014-11-11

申请号：US13884815

申请日：2012-11-01

Applicant: Davy Process Technology Limited

Inventor： Paul Appleton ,  Michael Anthony Wood ,  Robert Wild

IPC: C07C29/128 ,  C07C29/149 ,  C07C31/125

CPC classification number: C07C29/1285 ,  C07C29/128 ,  C07C29/149 ,  C07C31/125 ,  C07C67/03 ,  C07C67/08 ,  C07C69/26 ,  C07C69/24

Abstract: In a process for the production of fatty alcohol(s) a fatty acid or fatty acid mixture is subjected to esterification with a lower alkanol to form a stream comprising the corresponding lower alkyl ester or esters. The stream is vaporized and subjected to hydrogenation to form a stream comprising fatty alcohol(s) and an amount of unconverted lower alkyl ester(s). This stream is subjected to transesterification in a wax ester reactor in the presence of a solid transesterification catalyst. Fatty alcohol(s) and wax ester(s) are then separated by distillation to yield a fatty alcohol(s) product and a stream comprising wax ester(s). The stream of wax ester(s) is passed to a second hydrogenation zone to effect hydrogenation in the liquid phase to revert the wax ester(s) to fatty alcohol(s), which are returned to the distillation separation step.

Abstract translation: 在生产脂肪醇的方法中，脂肪酸或脂肪酸混合物用低级烷醇进行酯化以形成包含相应的低级烷基酯或酯的料流。 将物流蒸发并进行氢化以形成包含脂肪醇和一定量的未转化的低级烷基酯的物流。 在固体酯交换催化剂存在下，将该料流在蜡酯反应器中进行酯交换。 然后通过蒸馏分离脂肪醇和蜡酯，得到脂肪醇产物和包含蜡酯的物流。 将蜡酯流送入第二氢化区以在液相中进行氢化以将蜡酯还原成脂肪醇，将其返回至蒸馏分离步骤。