公开(公告)号：US12275805B2

公开(公告)日：2025-04-15

申请号：US17616352

申请日：2019-06-04

Applicant: NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY ,  DAICEL CORPORATION

Inventor： Daisuke Hirose ,  Masashi Genda ,  Naoki Wada ,  Kentaro Taki ,  Kenji Takahashi ,  Hiroyuki Matsumura

IPC: C08B3/00 ,  B29C48/40 ,  C08B3/06 ,  C08B3/18 ,  B29K1/00

Abstract: Provided is a method that enables industrially efficient production of an esterified polysaccharide product. A method for producing an esterified polysaccharide product, the method including reacting a polysaccharide-containing biomass, a basic ionic liquid with a pKa of a conjugate acid of an anion from 2 to 19 as a calculated value in a vacuum, and an esterifying agent using a kneader equipped with a shear force application mechanism. A cation constituting the basic ionic liquid is preferably one selected from the group consisting of an imidazolium cation, a pyridinium cation, and a tetraalkylammonium cation.

公开(公告)号：US20240360198A1

公开(公告)日：2024-10-31

申请号：US18687485

申请日：2022-09-01

Applicant: NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY ,  NISSAN CHEMICAL CORPORATION

Inventor： Rikinari HANAYAMA ,  Tomoyoshi YAMANO ,  Kazutaka MATOBA

IPC: C07K14/74 ,  A61K38/00 ,  A61P35/00 ,  C07K14/495 ,  C07K14/54 ,  C07K14/55 ,  C07K16/28

CPC classification number: C07K14/70539 ,  A61P35/00 ,  C07K14/495 ,  C07K14/5406 ,  C07K14/5412 ,  C07K14/5434 ,  C07K14/5443 ,  C07K14/55 ,  C07K16/28 ,  A61K38/00 ,  C07K2319/03

Abstract: Provided is a polynucleotide comprising at least one sequence encoding a fusion protein comprising (a) an antigen-presenting MHC molecule, which can be presented outside the membrane of a cell or an extracellular vesicle; (b) at least one T-cell stimulatory cytokine or subunit thereof, which can be presented outside the membrane of a cell or an extracellular vesicle; (c) a T-cell costimulatory molecule, which can be presented outside the membrane of a cell or an extracellular vesicle; (d) an antigen-presenting MHC molecule and at least one T-cell stimulatory cytokine or subunit thereof, which can be presented outside the membrane of a cell or an extracellular vesicle; or (e) an antigen-presenting MHC molecule, at least one T-cell stimulatory cytokine p or subunit thereof, and a T-cell costimulatory molecule, which can be presented outside the membrane of a cell or an extracellular vesicle.

公开(公告)号：US20240322208A1

公开(公告)日：2024-09-26

申请号：US18259914

申请日：2022-01-07

Applicant: JTEKT CORPORATION ,  NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY

Inventor： Takuya TSUJIGUCHI ,  Motoo NAKAI ,  Toshiyuki SAITO ,  Atsushi KUBO ,  Yasuhide TAKEDA ,  Mototake FURUHASHI ,  Tatsuma KOUCHI ,  Ayumi NAKASONE ,  Atsushi NAKANE

IPC: H01M8/04858 ,  H01M8/04223 ,  H01M8/04228 ,  H01M8/04303 ,  H01M8/04537 ,  H01M8/04746 ,  H01M8/04955 ,  H01M16/00

CPC classification number: H01M8/0494 ,  H01M8/04228 ,  H01M8/04231 ,  H01M8/04303 ,  H01M8/04559 ,  H01M8/04567 ,  H01M8/04589 ,  H01M8/04753 ,  H01M8/04947 ,  H01M8/04955 ,  H01M16/003

Abstract: A fuel cell system includes a fuel cell, an electric power recovery device, and a control device that controls the fuel cell and the electric power recovery device. In a state where supplying of the liquid fuel to the fuel cell is stopped, the control device charges post-stop electric power generated by the fuel cell using the liquid fuel that has been already supplied, thereby recovering the post-stop electric power into the electric power recovery device, and thereafter stopping an electrode reaction in an electrode structure of the fuel cell.

公开(公告)号：US20240238236A1

公开(公告)日：2024-07-18

申请号：US18561927

申请日：2022-05-19

Applicant: KAGAMI INC. ,  NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY

Inventor： Takashi WADA ,  Norihiko SAKAI ,  Yasunori IWATA ,  Yusuke NAKADE ,  Taku KOBAYASHI ,  Masashi MITA

IPC: A61K31/198 ,  A61K31/519 ,  A61P3/10

CPC classification number: A61K31/198 ,  A61K31/519 ,  A61P3/10

Abstract: The present invention provides a composition for regulating carbohydrate metabolism, the composition containing, as an active ingredient, an agent for controlling the amount of D-amino acid in the living body of a subject. Moreover, the present invention provides a method for assessing carbohydrate metabolism conditions of a subject by monitoring the amount of D-amino acid in the living body of the subject.

公开(公告)号：US11804610B2

公开(公告)日：2023-10-31

申请号：US17772965

申请日：2020-10-23

Applicant: JTEKT CORPORATION ,  NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY

Inventor： Takuya Tsujiguchi ,  Yasuhide Takeda ,  Atsushi Kubo ,  Akihiro Takazato ,  Toshiyuki Saito ,  Motoo Nakai ,  Yusuke Ueda

IPC: H01M8/04 ,  H01M8/04186 ,  H01M8/04746 ,  H01M8/0668 ,  H01M8/1011

CPC classification number: H01M8/04186 ,  H01M8/04746 ,  H01M8/0668 ,  H01M8/1011

Abstract: A fuel cell system having a direct liquid fuel cell that uses a liquid containing a formic acid or an alcohol as a fuel includes: a fuel tank that stores the fuel to be supplied to the fuel cell; a fuel supply device that supplies the fuel in the fuel tank to the fuel cell; and a bubbling device that blows an inert gas into the fuel stored in the fuel tank.

公开(公告)号：US20230275243A1

公开(公告)日：2023-08-31

申请号：US18005724

申请日：2021-08-25

Applicant: JTEKT CORPORATION ,  NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY

Inventor： Takuya TSUJIGUCHI ,  Yasuhide TAKEDA ,  Motoo NAKAI ,  Toshiyuki SAITO ,  Atsushi KUBO ,  Mototake FURUHASHI ,  Ayumi NAKASONE ,  Atsushi NAKANE ,  Fumitaka ACHIWA

IPC: H01M8/04291 ,  H01M8/0258 ,  H01M8/04186 ,  H01M8/1009

CPC classification number: H01M8/04291 ,  H01M8/0258 ,  H01M8/04186 ,  H01M8/1009 ,  H01M2008/1095

Abstract: A fuel cell includes a discharge structure that discharges water generated in a cathode electrode in association with an electrode reaction in the MEA to the outside. The discharge structure includes a discharge path through which air that is an oxidant flows, a passage that communicably connects an oxidant supply flow path and the discharge path and that moves water generated in the cathode electrode to the discharge path, and a discharge portion that discharges the generated water moved to the discharge path to the outside.

公开(公告)号：US20210351339A1

公开(公告)日：2021-11-11

申请号：US17284742

申请日：2019-03-08

Applicant: NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY

Inventor： Toshiyuki UENO ,  Tamotsu MINAMITANI

IPC: H01L41/12

Abstract: A power generation element and an actuator for vibration power generation is provided that can be mass-produced at low cost while achieving increase in electromotive force. A power generation element includes a main series magnetic circuit having a frame yoke made of magnetic material and provided with a fixed portion that is one end and a free portion that is the other end across a U-shaped bent portion, a main magnet that applies a magnetic bias to the frame yoke, and a first gap formed at a position in contact with the free portion; and an auxiliary series magnetic circuit having an auxiliary yoke made of magnetic material and attached to the frame yoke, an auxiliary magnet that gives a magnetic bias to the auxiliary yoke, a second gap formed at a position facing the first gap across the free portion, the frame yoke, the main magnet, and the first gap. The amount of change in a main magnetic flux passing in a coil wound around the frame yoke increases when the free portion vibrates due to application of an external force and a magnetic resistance of the first gap and a magnetic resistance of the second gap increase or decrease reciprocally.

公开(公告)号：US20210220309A1

公开(公告)日：2021-07-22

申请号：US16972898

申请日：2019-06-06

Applicant: National University Corporation Kanazawa University ,  Kagami Inc.

Inventor： Takashi WADA ,  Kengo FURUICHI ,  Norihiko SAKAI ,  Yasunori IWATA ,  Akinori HARA ,  Yusuke NAKADE ,  Kenji HAMASE ,  Masashi MITA

IPC: A61K31/198 ,  A61P13/12 ,  A61K9/00

Abstract: The present invention pertains to a pharmaceutical composition for the prevention or treatment of kidney disease, a kidney inflammation inhibitor, an inflammatory cell death inhibitor for the kidneys, or a food for the prevention or improvement of kidney disease, that include D-alanine or a derivative thereof. In addition, the present invention pertains to the use of D-alanine or a derivative thereof, for the production of a pharmaceutical composition for the prevention or treatment of kidney disease.

公开(公告)号：US11066757B2

公开(公告)日：2021-07-20

申请号：US16179363

申请日：2018-11-02

Applicant: SHIN-ETSU CHEMICAL CO., LTD. ,  National Institute of Advanced Industrial Science and Technology ,  NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY

Inventor： Hitoshi Noguchi ,  Shozo Shirai ,  Toshiharu Makino ,  Masahiko Ogura ,  Hiromitsu Kato ,  Hiroyuki Kawashima ,  Daisuke Kuwabara ,  Satoshi Yamasaki ,  Daisuke Takeuchi ,  Norio Tokuda ,  Takao Inokuma ,  Tsubasa Matsumoto

IPC: C30B29/04 ,  C30B25/04 ,  H01L21/02 ,  C30B25/18 ,  C30B25/20 ,  H01L29/16 ,  H01L21/3065 ,  H01L21/308

Abstract: A method for manufacturing a diamond substrate, including: a first step of preparing patterned diamond on a foundation surface, a second step of growing diamond from the patterned diamond prepared in the first step to form the diamond in a pattern gap of the patterned diamond prepared in the first step, a third step of removing the patterned diamond prepared in the first step to form a patterned diamond composed of the diamond formed in the second step, and a fourth step of growing diamond from the patterned diamond formed in the third step to form the diamond in a pattern gap of the patterned diamond formed in the third step. There can be provided a method for manufacturing a diamond substrate which can sufficiently suppress dislocation defects, a high-quality diamond substrate, and a freestanding diamond substrate.

公开(公告)号：US20210122790A1

公开(公告)日：2021-04-29

申请号：US16766596

申请日：2018-11-22

Applicant: NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY ,  OSAKA UNIVERSITY

Inventor： Yukako FUJINAGA ,  Sho AMATSU ,  Masahiro KINOOKA

IPC: C07K14/33 ,  C12N15/85

Abstract: The present invention provides a miniaturized hemagglutinin complex protein having function inhibitory activity against E-cadherin, wherein (a) all or a part of at least HA1 subcomponent, and/or a part of HA3 subcomponent are/is deleted, (b) regions in HA2 and HA3 subcomponents that contribute to binding with E-cadherin are present, and (c) the HA3 subcomponent is derived from Clostridium botulinum type A or type B, and an E-cadherin function inhibitor containing the hemagglutinin complex protein.