公开(公告)号：US12152011B2

公开(公告)日：2024-11-26

申请号：US17284306

申请日：2019-10-10

Applicant: SEOUL NATIONAL UNIVERSITY HOSPITAL

Inventor： Chan Yeong Heo ,  So Min Kang ,  Da Som Jeon

IPC: A61P37/08 ,  A23L33/10 ,  A61P17/02 ,  C07D307/91

Abstract: The present invention relates to a novel Usnic acid derivative exhibiting an inhibitory effect on TSLP secretion or pharmaceutically acceptable salts thereof, and a use thereof.

公开(公告)号：US12146558B2

公开(公告)日：2024-11-19

申请号：US17797394

申请日：2021-02-09

Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

Inventor： Jaeheung Park ,  Seung Bin You

IPC: F16H49/00 ,  F16H1/32

Abstract: Provided is a plate harmonic reducer, and more particularly, a plate harmonic reducer, in which design may be further simplified and a manufacturing cost may be reduced.

公开(公告)号：US20240378749A1

公开(公告)日：2024-11-14

申请号：US18656127

申请日：2024-05-06

Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

Inventor： Sungchan PARK ,  Joonseok LEE ,  Eunyi LYOU ,  Inhoe LEE

IPC: G06T7/73

Abstract: A training data augmentation method for three-dimensional (3D) pose estimation includes collecting foot coordinates of each of persons appearing in a two-dimensional image, estimating a ground plane in a three-dimensional space based on the collected foot coordinates, generating three-dimensional pose data by moving or rotating at least one person or moving or rotating the ground plane based on two basis vectors perpendicular to a normal vector of the ground plane, mapping the 3D pose data to two-dimensional pose data based on a focal length of a camera obtained by capturing the two-dimensional image and a principal point of coordinates of the two-dimensional image, and acquiring a pair of the 3D pose data and two-dimensional pose data as training data.

公开(公告)号：US20240363244A1

公开(公告)日：2024-10-31

申请号：US18560370

申请日：2022-05-13

Applicant: UIF (University Industry Foundation), Yonsei University ,  SEOUL NATIONAL UNIVERSITY HOSPITAL

Inventor： Jong Yun WON ,  Ki Chang HAN ,  Jae Hyon PARK ,  In Sun PARK

IPC: G16H50/20 ,  G16H10/60 ,  G16H50/50

CPC classification number: G16H50/20 ,  G16H10/60 ,  G16H50/50

Abstract: A method and a device for predicting stenosis of a dialysis access by using a convolutional neural network (CNN) according to a preferable embodiment of the present invention can predict, from audio data with respect to a dialysis access of an object, a degree of stenosis of the dialysis access on the basis of a stenosis prediction model including a convolutional neural network so as to predict the degree of stenosis of the dialysis access more precisely and guide an additional examination and treatment according thereto.

公开(公告)号：US12122812B2

公开(公告)日：2024-10-22

申请号：US16979078

申请日：2019-03-05

Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

Inventor： Byeong Moon Kim ,  Yan Lee ,  Eun Joung Choi ,  Dongwook Jung

IPC: C07K1/13 ,  A61K47/60 ,  C07K14/505 ,  C07K19/00 ,  A61K38/00

CPC classification number: C07K14/505 ,  A61K47/60 ,  C07K19/00 ,  C12Y304/21001 ,  A61K38/00

Abstract: Disclosed are a method for preparing a biomaterial having selectively functionalized tyrosine, a biomaterial having selectively functionalized tyrosine, and a pharmaceutical composition containing same as an active ingredient. The method for preparing a biomaterial to which a compound represented by chemical formula 2 is coupled, of the present invention, allows the compound represented by chemical formula 2 to be selectively coupled, in a high yield in a biomaterial, to tyrosine, which is present on the surface of an aqueous solution such that the coupling thereof to amino acids other than tyrosine does not occur and, when only one tyrosine is present, heterogeneous mixtures are not present and the inherent activity of the biomaterial is maintained, and thus the compound can be effectively used as a pharmaceutical composition containing a biomaterial drug as an active ingredient. In addition, the method can selectively functionalize tyrosine, and thus can be effectively used for tyrosine functionalization in a biomaterial.

公开(公告)号：US20240349512A1

公开(公告)日：2024-10-17

申请号：US18635072

申请日：2024-04-15

Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

Inventor： Jae-Joon KIM ,  Munhyeon KIM

IPC: H10B53/30

CPC classification number: H10B53/30

Abstract: A memory using ferroelectric metal field-effect transistors includes a drain, a source, and a gate formed on a substrate, a gate contact formed on an upper portion of the gate, and a ferroelectric layer disposed between the gate contact and the gate and configured to surround the gate contact, wherein the gate, the ferroelectric layer, and the gate contact operate as a capacitor having a metal-ferroelectric layer-metal (MFM) structure.

公开(公告)号：US20240349477A1

公开(公告)日：2024-10-17

申请号：US18635211

申请日：2024-04-15

Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

Inventor： Jae-Joon KIM ,  Munhyeon KIM

IPC: H10B12/00

CPC classification number: H10B12/00

Abstract: A random access memory includes a first transistor including a first gate extending in a first direction, a second transistor including a second gate extending in a second direction perpendicular to the first direction and formed on an upper portion of the first transistor, and a storage node configured to connect a first gate of the first transistor to a drain of the second transistor and storing data.

公开(公告)号：US20240347105A1

公开(公告)日：2024-10-17

申请号：US18635268

申请日：2024-04-15

Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

Inventor： Jae-Joon KIM ,  Munhyeon KIM

IPC: G11C11/419 ,  G11C5/06 ,  H01L29/06 ,  H01L29/417 ,  H01L29/423 ,  H01L29/66 ,  H01L29/775 ,  H01L29/786 ,  H10B10/00

CPC classification number: G11C11/419 ,  G11C5/063 ,  H01L29/0673 ,  H01L29/41733 ,  H01L29/42392 ,  H01L29/66439 ,  H01L29/775 ,  H01L29/78696 ,  H10B10/125

Abstract: A random access memory includes a first transistor including a first gate extending in a first direction, a second transistor disposed on a same plane as the first transistor and including a second gate extending in the first direction, a third transistor including a third gate extending in a second direction perpendicular to the first direction and formed on the first transistor, a fourth transistor including a fourth gate extending in the second direction and formed on the second transistor, a first storage node connecting the first gate of the first transistor to a drain of the third transistor and storing data, and a second storage node connecting the second gate of the second transistor to a drain of the fourth transistor and storing data.

公开(公告)号：US20240336690A1

公开(公告)日：2024-10-10

申请号：US18293425

申请日：2022-08-01

Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION ,  EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION

Inventor： JUN HO CHUNG ,  KYUNG HO CHOI ,  SANG IL KIM ,  YOUNG JAE LEE ,  SU JEONG KIM ,  SEO RYEONG PARK ,  SI WON HWANG ,  DONG MIN KANG ,  SU REE KIM

IPC: C07K16/28 ,  A61K47/68

CPC classification number: C07K16/2875 ,  A61K47/6803 ,  A61K47/68031 ,  A61K47/6849 ,  C07K2317/622 ,  C07K2317/76

Abstract: An antibody binds to CD154. The antibody includes HCDR, which includes amino acid sequences of SEQ ID NOs: 1 to 3, and LCDR which includes amino acid sequences of SEQ ID NOs: 4 to 6. A composition including an antibody-drug conjugate in which a drug is conjugated to the antibody may prevent or treat a T cell-mediated autoimmune disease and/or organ transplant rejection.

公开(公告)号：US20240321067A1

公开(公告)日：2024-09-26

申请号：US18612259

申请日：2024-03-21

Applicant: POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION ,  Seoul National University R&DB Foundation

Inventor： Moon Jeong Park ,  Yong-Lae Park ,  Myungsun Park ,  HYEON SEONG HAM

IPC: G08B6/00 ,  G01L1/22

CPC classification number: G08B6/00 ,  G01L1/2287

Abstract: Haptic interaction system remotely operated by human hand through real-time haptic feedback, and a sensor-integrated iEAP actuator included in the system are provided, in which when a gripper including the sensor-integrated iEAP actuator that operates in conjunction with the user's finger movements comes into contact with an object, changes in signal of the sensor included in the sensor-integrated iEAP actuator are transmitted to the user as haptic feedback in real time, thereby enabling stable gripping without a visual sensor.