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公开(公告)号:US07033755B2
公开(公告)日:2006-04-25
申请号:US09796008
申请日:2001-02-28
申请人: Abbot F. Clark , John Fingert , Loretta McNatt , Edwin M. Stone , Wan-Heng Wang
发明人: Abbot F. Clark , John Fingert , Loretta McNatt , Edwin M. Stone , Wan-Heng Wang
CPC分类号: G01N33/5091 , A61K38/00 , C07K14/47 , C12N9/12 , C12Q1/485 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , G01N33/5008 , G01N33/5041 , G01N33/5044 , G01N33/6893 , G01N2800/168
摘要: Methods and compositions for diagnosing and treating glaucoma are disclosed.
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82.
公开(公告)号:US06172054B2
公开(公告)日:2001-01-09
申请号:US08491005
申请日:1995-06-15
申请人: Abbot F. Clark
发明人: Abbot F. Clark
IPC分类号: A61K3156
CPC分类号: A61K45/06 , A61K31/5377 , A61K31/573 , Y10S514/913 , A61K2300/00
摘要: Angiostatic agents and another IOP lowering compound are combined in ophthalmic compositions to treat glaucoma and ocular hypertension. Methods for treating glaucoma and ocular hypertension are also disclosed.
摘要翻译: 将血管抑制剂和另一种降低IOP的化合物组合在眼用组合物中以治疗青光眼和高眼压症。 还公开了治疗青光眼和高眼压症的方法。
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83.Treatment of GLC1A glaucoma with non-steroidal glucocorticoid antagonists 失效
标题翻译: 用非甾体糖皮质激素拮抗剂治疗GLC1A青光眼公开(公告)号:US6051573A
公开(公告)日:2000-04-18
申请号:US994957
申请日:1997-12-19
申请人: Abbot F. Clark
发明人: Abbot F. Clark
IPC分类号: A61K45/00 , A01N43/36 , A01N43/40 , A01N43/60 , A01N43/64 , A61K31/00 , A61K31/166 , A61K31/40 , A61K31/41 , A61K31/415 , A61K31/4439 , A61K31/495 , A61K31/496 , A61K31/535 , A61K31/5375 , A61K31/5377 , A61P27/06 , C07D207/04 , C07D231/10 , C07D265/30
CPC分类号: A61K31/00
摘要: Compositions of non-steroidal glucocorticoid antagonists for treating GLC1A glaucoma and methods for their use are disclosed.
摘要翻译: 公开了用于治疗GLC1A青光眼的非类固醇糖皮质激素拮抗剂的组合物及其使用方法。
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84.A-seco steroids effective at treating ophthalmic pathological neovascularization and controlling intraocular pressure 失效
标题翻译: A-seco类固醇有效治疗眼科病理性新血管形成和控制眼内压公开(公告)号:US5929111A
公开(公告)日:1999-07-27
申请号:US992418
申请日:1997-12-17
申请人: Raymond E. Conrow , Abbot F. Clark
发明人: Raymond E. Conrow , Abbot F. Clark
IPC分类号: A61K31/00 , A61K31/215 , A61K31/19 , A61K31/58 , A61K31/585
CPC分类号: A61K31/00
摘要: A-seco steroids are disclosed. Methods of use are disclosed for treating ophthalmic pathological neovascularization and controlling intraocular pressure.
摘要翻译: 公开了一种类固醇。 公开了用于治疗眼病理性新血管形成和控制眼内压的方法。
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公开(公告)号:US5700794A
公开(公告)日:1997-12-23
申请号:US674303
申请日:1996-07-01
申请人: Abbot F. Clark
发明人: Abbot F. Clark
CPC分类号: A61K31/573 , A61K31/58 , Y10S514/912
摘要: Methods for treating ocular hypotony are disclosed.
摘要翻译: 公开了治疗眼低血压的方法。
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86.Substituted hydrindanes for the treatment of angiogenesis-dependent diseases 失效
标题翻译: 用于治疗血管生成依赖性疾病的取代的氢化茚公开(公告)号:US5464866A
公开(公告)日:1995-11-07
申请号:US209325
申请日:1994-03-10
申请人: Abbot F. Clark , Raymond E. Conrow
发明人: Abbot F. Clark , Raymond E. Conrow
IPC分类号: A61K31/045 , A61K31/075 , A61K31/095 , A61K31/10 , A61K31/11 , A61K31/12 , A61K31/16 , A61K31/19 , A61K31/255 , A61K31/27 , A61K31/275 , A61K31/41 , A61K31/415 , A61K31/66 , C07C235/26 , C07C271/38 , C07C309/73 , C07C317/18 , C07C323/52 , C07D233/84 , C07D285/08
CPC分类号: C07D285/08 , A61K31/045 , A61K31/075 , A61K31/095 , A61K31/10 , A61K31/11 , A61K31/12 , A61K31/16 , A61K31/19 , A61K31/255 , A61K31/27 , A61K31/275 , A61K31/41 , A61K31/415 , A61K31/66 , C07C235/26 , C07C271/38 , C07C309/73 , C07C317/18 , C07C323/52 , C07D233/84 , C07C2102/24
摘要: Substituted hydrindanes and their use in controlling angiogenesis-dependent diseases in warm blooded animals are disclosed.
摘要翻译: 公开了取代的氢化茚并及其在控制温血动物中血管生成依赖性疾病中的用途。
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87.Angiostatic steroids and methods and compositions for controlling ocular hypertension 失效
标题翻译: 静脉注射类固醇以及用于控制高眼压症的方法和组合物公开(公告)号:US5371078A
公开(公告)日:1994-12-06
申请号:US941485
申请日:1992-09-08
申请人: Abbot F. Clark , Raymond E. Conrow
发明人: Abbot F. Clark , Raymond E. Conrow
IPC分类号: A61K31/56 , A61K31/565 , A61K31/57 , A61K31/58 , A61K31/665 , C07J3/00 , C07J5/00 , C07J9/00 , C07J11/00 , C07J41/00 , C07J51/00
CPC分类号: A61K31/569 , A61K31/56 , A61K31/565 , A61K31/57 , A61K31/573 , A61K31/58 , A61K31/665 , C07J11/00 , C07J3/00 , C07J41/0005 , C07J41/0027 , C07J5/0053 , C07J51/00 , C07J9/00
摘要: Angiostatic steroids for use in controlling ocular hypertension are disclosed. Pharmaceutical compositions of the angiostatic steroids and methods for their use in treating ocular hypertension, including controlling the ocular hypertension associated with primary open angle glaucoma, are disclosed. In addition, the combination of the compounds with glucocorticoids for the prevention of elevated IOP during the treatment of inflammation is disclosed.
摘要翻译: 公开了用于控制高眼压症的止血类固醇。 公开了血管抑制类固醇的药物组合物及其用于治疗高眼压症的方法,包括控制与原发性开角型青光眼相关的眼压高血压。 此外,公开了在治疗炎症期间化合物与糖皮质激素的组合用于预防升高的IOP。
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88.
公开(公告)号:US4876250A
公开(公告)日:1989-10-24
申请号:US264918
申请日:1988-10-31
申请人: Abbot F. Clark
发明人: Abbot F. Clark
IPC分类号: A61K31/565 , A61K31/57 , A61K31/58 , A61K31/665 , A61P27/02 , C07J3/00 , C07J5/00 , C07J7/00 , C07J9/00 , C07J11/00 , C07J17/00 , C07J33/00 , C07J41/00 , C07J43/00 , C07J51/00 , C07J71/00
CPC分类号: A61K31/569 , A61K31/565 , A61K31/57 , A61K31/573 , A61K31/58 , A61K31/665 , C07J11/00 , C07J3/00 , C07J41/0005 , C07J41/0027 , C07J5/0053 , C07J51/00 , C07J9/00
摘要: Angiostatic steroids for use in controlling ocular hypertension are disclosed. Pharmaceutical composition of the angiostatic steroids and methods for their use in treating ocular hypertension, including controlling the ocular hypertension associated with primary open angle glaucoma, are disclosed.
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