公开(公告)号：US20210045663A1

公开(公告)日：2021-02-18

申请号：US17088262

申请日：2020-11-03

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  James H. Brauker ,  Mark C. Brister ,  Paul V. Goode, JR. ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  Jack Pryor ,  Matthew D. Wightlin

IPC: A61B5/145 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/00 ,  A61B5/1495 ,  A61B5/15 ,  A61B5/05 ,  A61B17/34

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

公开(公告)号：US10918318B2

公开(公告)日：2021-02-16

申请号：US16742807

申请日：2020-01-14

Applicant: DexCom, Inc.

Inventor： Jack Pryor ,  Apurv Ullas Kamath ,  Paul V. Goode, Jr. ,  James H. Brauker ,  Aarthi Mahalingam

IPC: A61B5/1495 ,  A61B5/1473 ,  A61B5/1468 ,  A61B5/1486 ,  A61B5/00 ,  A61B5/145

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

公开(公告)号：US20200367794A1

公开(公告)日：2020-11-26

申请号：US16924101

申请日：2020-07-08

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  James H. Brauker ,  Mark C. Brister ,  Paul V. Goode, Jr. ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  Jack Pryor ,  Matthew D. Wightlin

IPC: A61B5/145 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/00 ,  A61B5/1495 ,  A61B5/15 ,  A61B5/05 ,  A61B17/34

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

公开(公告)号：US20200261650A1

公开(公告)日：2020-08-20

申请号：US16867476

申请日：2020-05-05

Applicant: DexCom, Inc.

Inventor： John Michael Dobbles ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  James H. Brauker

IPC: A61M5/172 ,  A61M15/00 ,  A61M5/20 ,  A61M5/142 ,  G16H40/63 ,  A61M11/00 ,  A61B5/145

Abstract: Systems and methods for integrating a continuous glucose sensor 12, including a receiver 14, a medicament delivery device 16, a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and/or fully automated.

公开(公告)号：US20200096495A1

公开(公告)日：2020-03-26

申请号：US16698498

申请日：2019-11-27

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Arturo Garcia ,  Hari Hampapuram ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  Dmytro Sokolovskyy ,  Stephen J. Vanslyke

IPC: G01N33/487 ,  G16C20/80 ,  G16C99/00 ,  G01M99/00 ,  A61B5/145 ,  A61B5/1495 ,  G01N33/49 ,  G01N33/66 ,  A61B5/00

Abstract: Systems and methods for processing sensor data and end of life detection are provided. In some embodiments, a method for determining the end of life of a continuous analyte sensor includes evaluating a plurality of risk factors using an end of life function to determine an end of life status of the sensor and providing an output related to the end of life status of the sensor. The plurality of risk factors may be selected from the list including the number of days the sensor has been in use, whether there has been a decrease in signal sensitivity, whether there is a predetermined noise pattern, whether there is a predetermined oxygen concentration pattern, and error between reference BG values and EGV sensor values.

公开(公告)号：US10588557B2

公开(公告)日：2020-03-17

申请号：US15213259

申请日：2016-07-18

Applicant: DexCom, Inc.

Inventor： Michael J. Estes ,  Stephen J. Vanslyke ,  Apurv Ullas Kamath ,  Thomas A. Peyser ,  Lucas Bohnett ,  Aarthi Mahalingam ,  Arturo Garcia ,  Peter C. Simpson ,  Anna Leigh Davis ,  Sebastian Böhm

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1495 ,  G01D3/02 ,  G06F19/00

Abstract: Systems and methods for applying time-dependent algorithmic compensation functions to data output from a continuous analyte sensor. Some embodiments determine a time since sensor implantation and/or whether a newly initialized sensor has been used previously, for example, by initializing a sensor, acquiring sensor data, using the sensor, to measure an analyte level in the host's body over a first interval based on a first elapsed time since the sensor was implanted, determining whether the sensor has been previously used in a previous sensor session or the sensor is a new sensor, and upon determining the sensor is a new sensor, adjusting the acquired sensor data to compensate for sensor drift of the new sensor by applying a first set of time-dependent algorithmic functions to the sensor data associated with the first interval.

公开(公告)号：US10506982B2

公开(公告)日：2019-12-17

申请号：US13899905

申请日：2013-05-22

Applicant: DexCom, Inc.

Inventor： Apurv Ullas Kamath ,  Michael Robert Mensinger ,  Ying Li ,  Aarthi Mahalingam ,  J. Michael Dobbles

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/1495 ,  G06F19/00 ,  A61M5/172 ,  G16H20/00 ,  A61B5/01 ,  G16H40/63 ,  G16H40/40 ,  G16H50/50 ,  G16H15/00

Abstract: Systems and methods for processing sensor data are provided. In some embodiments, systems and methods are provided for calibration of a continuous analyte sensor. In some embodiments, systems and methods are provided for classification of a level of noise on a sensor signal. In some embodiments, systems and methods are provided for determining a rate of change for analyte concentration based on a continuous sensor signal. In some embodiments, systems and methods for alerting or alarming a patient based on prediction of glucose concentration are provided.

公开(公告)号：US20190298922A1

公开(公告)日：2019-10-03

申请号：US16445055

申请日：2019-06-18

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Arturo Garcia ,  Phil Mayou ,  Thomas A. Peyser ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  Kevin Sayer ,  Thomas Hall ,  Michael Robert Mensinger ,  Hari Hampapuram ,  David Price ,  Jorge Valdes ,  Murrad Kazalbash

IPC: A61M5/172 ,  G16H50/30 ,  A61M5/142 ,  G01N33/49 ,  G16H40/63

Abstract: Methods and apparatus, including computer program products, are provided for processing analyte data. In some example implementations, a method may include generating glucose sensor data indicative of a host's glucose concentration using a glucose sensor; calculating a glycemic variability index (GVI) value based on the glucose sensor data; and providing output to a user responsive to the calculated glycemic variability index value. The GVI may be a ratio of a length of a line representative of the sensor data and an ideal length of the line. Related systems, methods, and articles of manufacture are also disclosed.

公开(公告)号：US20190209095A1

公开(公告)日：2019-07-11

申请号：US16356599

申请日：2019-03-18

Applicant: DexCom, Inc.

Inventor： Apurv Ullas Kamath ,  James H. Brauker ,  Aarthi Mahalingam ,  Ying Li

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/01

CPC classification number: A61B5/7203 ,  A61B5/01 ,  A61B5/145 ,  A61B5/14532 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/14865 ,  A61B5/6848 ,  A61B5/7225 ,  A61B5/7239 ,  A61B5/7257 ,  A61B5/726 ,  A61B5/742 ,  A61B2560/0252 ,  Y02A90/22 ,  Y02A90/26

Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as interfering species, ischemia, pH changes, temperatures changes, known or unknown sources of mechanical, electrical and/or biochemical noise, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system processes some or the entire data stream continually or intermittently based at least in part on whether the signal artifact event has occurred.

公开(公告)号：US20190090789A1

公开(公告)日：2019-03-28

申请号：US16202984

申请日：2018-11-28

Applicant: DexCom, Inc.

Inventor： Apurv Ullas Kamath ,  John Michael Dobbles ,  Aarthi Mahalingam

IPC: A61B5/1477 ,  A61B5/00 ,  A61B5/1495 ,  A61B5/145 ,  A61B5/1486

Abstract: Systems and methods for processing sensor data are provided. In some embodiments, systems and methods are provided for calibration of a continuous analyte sensor. In some embodiments, systems and methods are provided for classification of a level of noise on a sensor signal. In some embodiments, systems and methods are provided for determining a rate of change for analyte concentration based on a continuous sensor signal. In some embodiments, systems and methods for alerting or alarming a patient based on prediction of glucose concentration are provided.