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公开(公告)号：US20240199589A1
公开(公告)日：2024-06-20
申请号：US18496137
申请日：2023-10-27
Applicant: Gilead Sciences, Inc.
Inventor： Megan K. Armstrong , James S. Cassidy , Elbert Chin , Chienhung Chou , Jeromy J. Cottell , Chao-I Hung , Kavoos Kolahdouzan , David W. Lin , Michael L. Mitchell , Ezra Roberts , Scott D. Schroeder , Nathan D. Shapiro , James G. Taylor , Rhiannon Thomas-Tran , Nathan E. Wright , Zheng-Yu Yang
IPC: C07D405/14 , A61K31/437 , A61K31/4439 , A61K31/497 , A61K31/506 , A61K31/5377 , A61K31/675 , C07D401/08 , C07D401/10 , C07D401/14 , C07D409/14 , C07D417/14 , C07D471/04 , C07D491/048 , C07D493/08 , C07D493/10 , C07F9/6558
CPC classification number: C07D405/14 , A61K31/437 , A61K31/4439 , A61K31/497 , A61K31/506 , A61K31/5377 , A61K31/675 , C07D401/08 , C07D401/10 , C07D401/14 , C07D409/14 , C07D417/14 , C07D471/04 , C07D491/048 , C07D493/08 , C07D493/10 , C07F9/65586
Abstract: The present disclosure provides GLP-1R agonists, and compositions, methods, and kits thereof. Such compounds are generally useful for treating a GLP-1R mediated disease or condition in a human.
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公开(公告)号：US20240199580A1
公开(公告)日：2024-06-20
申请号：US18502972
申请日：2023-11-06
Applicant: Gilead Sciences, Inc.
Inventor： Gediminas J. Brizgys , James S. Cassidy , Chienhung Chou , Jeromy J. Cottell , Chao-I Hung Hung , Kavoos Kolahdouzan , James G. Taylor , Nathan E. Wright , Zheng-Yu Yang
IPC: C07D401/14 , A61K45/06 , C07D405/14
CPC classification number: C07D401/14 , A61K45/06 , C07D405/14
Abstract: The present disclosure provides GLP-1R agonists, and compositions, methods, and kits thereof. Such compounds are generally useful for treating a GLP-1R mediated disease or condition in a human.
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公开(公告)号：US20230102927A1
公开(公告)日：2023-03-30
申请号：US17724212
申请日：2022-04-19
Applicant: Gilead Sciences, Inc.
Inventor： Megan K. Armstrong , James S. Cassidy , Elbert Chin , Chienhung Chou , Jeromy J. Cottell , Chao-I Hung , Kavoos Kolahdouzan , David W. Lin , Michael L. Mitchell , Ezra Roberts , Scott D. Schroeder , Nathan D. Shapiro , James G. Taylor , Rhiannon Thomas-Tran , Nathan E. Wright , Zheng-Yu Yang
IPC: C07D405/14 , C07D401/14 , C07D401/10 , C07D401/08 , C07D471/04 , A61K31/4439 , C07D491/048 , A61K31/497 , A61K31/437 , A61K31/506 , A61K31/5377 , C07D409/14 , C07D493/08 , C07D493/10 , C07D417/14 , C07F9/6558 , A61K31/675
Abstract: The present disclosure provides GLP-1R agonists, and compositions, methods, and kits thereof. Such compounds are generally useful for treating a GLP-1R mediated disease or condition in a human.
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![Pyrrolo[1,2-b]pyridazine derivatives](/abs-image/US/2023/02/07/US11572362B2/abs.jpg.150x150.jpg)
公开(公告)号：US11572362B2
公开(公告)日：2023-02-07
申请号：US16539753
申请日：2019-08-13
Applicant: Gilead Sciences, Inc.
Inventor： Stephen Ammann , Elizabeth M. Bacon , Gediminas Brizgys , Elbert Chin , Chienhung Chou , Jeromy J. Cottell , Marilyn Ndukwe , James G. Taylor , Nathan E. Wright , Zheng-Yu Yang , Sheila M. Zipfel
IPC: C07D487/04 , A61P29/00
Abstract: A compound of Formula (I): pharmaceutically acceptable salts thereof, deuterated analogs thereof, compositions thereof, and methods of treating disease using a compound thereof are disclosed.
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公开(公告)号：US20230021705A1
公开(公告)日：2023-01-26
申请号：US17723758
申请日：2022-04-19
Applicant: Gilead Sciences, Inc.
Inventor： Megan K. Armstrong , Gediminas J. Brizgys , James S. Cassidy , Elbert Chin , Chienhung Chou , Chao-I Hung , David W. Lin , Michael L. Mitchell , Ezra Roberts , Scott D. Schroeder , James G. Taylor , Rhiannon Thomas-Tran , Nathan E. Wright , Zheng-Yu Yang
IPC: A61K31/5383 , C07D417/14 , C07D405/14 , C07D498/04 , C07D413/14 , C07D513/04 , C07D471/04 , C07D487/04 , C07D409/14 , C07D401/14 , C07D491/08 , C07D495/04 , A61K45/06 , A61K31/423 , A61K31/137 , A61K31/357 , A61K31/135 , A61K38/22 , A61K31/5375 , A61K31/4188 , A61K35/60 , A61K31/4439 , A61K31/437 , A61K31/519 , A61K31/4985 , A61K31/444 , A61K31/4995 , A61K31/497 , A61K31/5377 , A61K31/4545 , C07D401/10 , A61K31/427 , A61K31/433 , C07D403/12
Abstract: The present disclosure provides GLP-1R agonists, and compositions, methods, and kits thereof. Such compounds are generally useful for treating a GLP-1R mediated disease or condition in a human.
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Patent Agency Ranking
公开(公告)号：US11325930B2
公开(公告)日：2022-05-10
申请号：US17162754
申请日：2021-01-29
Applicant: Gilead Sciences, Inc.
Inventor： Eda Y. Canales , Manoj C. Desai , Eric Gorman , Jiayao Li , Roland D. Saito , James G. Taylor , Nathan E. Wright
IPC: C07D401/14 , C07F9/6558
Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
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公开(公告)号：US20210147454A1
公开(公告)日：2021-05-20
申请号：US17162754
申请日：2021-01-29
Applicant: Gilead Sciences, Inc.
Inventor： Eda Y. Canales , Manoj C. Desai , Eric Gorman , Jiayao Li , Roland D. Saito , James G. Taylor , Nathan E. Wright
IPC: C07F9/6558 , C07D401/14
Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
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![Substituted 3,4,5,6,8,10,14,14a-octahydro-2h-2,6-methanopyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazocines and methods for treating viral infections](/abs-image/US/2020/06/23/US10689399B2/abs.jpg.150x150.jpg)
公开(公告)号：US10689399B2
公开(公告)日：2020-06-23
申请号：US16017371
申请日：2018-06-25
Applicant: Gilead Sciences, Inc.
Inventor： Elizabeth M. Bacon , Zhenhong R. Cai , Xiaowu Chen , Jeromy J. Cottell , Manoj C. Desai , Mingzhe Ji , Haolun Jin , Scott E. Lazerwith , Michael R. Mish , Philip Anthony Morganelli , Hyung-Jung Pyun , James G. Taylor , Teresa Alejandra Trejo Martin
IPC: A61K31/4985 , C07D413/14 , C07D498/14 , A61K31/537 , C07D471/22 , A61K31/529 , A61K31/551 , A61K31/498 , C07D471/18 , A61K45/06 , C07D498/18 , C07D487/14 , A61K31/553
Abstract: Compounds for use in the treatment of human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following Formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, X, W, Y1, Y2, Z1, and Z4 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
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公开(公告)号：US10577352B2
公开(公告)日：2020-03-03
申请号：US16045518
申请日：2018-07-25
Applicant: Gilead Sciences, Inc.
Inventor： Gayatri Balan , Chienhung Chou , Musong Kim , Thorsten A. Kirschberg , John O. Link , Gary Phillips , Roland D. Saito , Neil H. Squires , James G. Taylor , William J. Watkins , Nathan E. Wright
IPC: C07D401/14 , C07D403/12 , C07D405/14 , C07D417/14
Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
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公开(公告)号：US20190248807A1
公开(公告)日：2019-08-15
申请号：US16391673
申请日：2019-04-23
Applicant: Gilead Sciences, Inc.
Inventor： Elizabeth M. Bacon , Gayatri Balan , Chienhung Chou , Christopher T. Clark , Jeromy J. Cottell , Musong Kim , Thorsten A. Kirschberg , John O. Link , Gary B. Phillips , Scott D. Schroeder , Neil H. Squires , Kirk L. Stevens , James G. Taylor , William J. Watkins , Nathan E. Wright , Sheila M. Zipfel
IPC: C07D498/04 , C07D495/04 , C07D471/04 , C07D417/14 , C07D409/14 , C07B59/00 , C07D413/14 , C07D405/14 , C07D401/14 , C07D401/12
CPC classification number: C07D498/04 , C07B59/002 , C07B2200/05 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D495/04
Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
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