公开(公告)号：US20060185849A1

公开(公告)日：2006-08-24

申请号：US11307647

申请日：2006-02-15

申请人： John Edwards ,  Ronan Le Gloahec ,  Claude Vercaemer ,  Philippe Hocquet ,  Pierre-Yves Corre ,  Nitin Vaidya

发明人： John Edwards ,  Ronan Le Gloahec ,  Claude Vercaemer ,  Philippe Hocquet ,  Pierre-Yves Corre ,  Nitin Vaidya

IPC分类号： E21B43/10

CPC分类号： E21B43/08 ,  E21B36/00 ,  E21B43/12

摘要： An apparatus includes a base pipe and a fluid control material. The base pipe includes openings, and the fluid control material is mounted to the pipe to control fluid communication through the openings of the pipe. The fluid control material has a permeability that may be changed to selectively control the communication of well fluid through the openings.

摘要翻译： 一种装置包括基管和流体控制材料。 基管包括开口，并且流体控制材料安装到管道上以控制通过管道的开口的流体连通。 流体控制材料具有可以改变的渗透性，以选择性地控制通过开口的井液的连通。

公开(公告)号：US20060143528A1

公开(公告)日：2006-06-29

申请号：US11118869

申请日：2005-04-29

申请人： John Edwards ,  Michael Budwey

发明人： John Edwards ,  Michael Budwey

IPC分类号： G06F11/00

CPC分类号： G06F11/2097 ,  G06F11/1658

摘要： The invention relates to checkpointing memory. In one aspect, a processor directs a write request to a location within a first memory. The write request includes at least a data payload and an address identifying the location. An inspection module identifies the write request before it reaches the first memory, copies at least the address identifying the location, and forwards the write request to a memory agent within the first memory.

公开(公告)号：US20060083750A1

公开(公告)日：2006-04-20

申请号：US11123873

申请日：2005-05-05

申请人： John Edwards ,  Scott Filler ,  Donald Sheppard ,  Ashraf Ibrahim ,  Yue Fu ,  Brad Spellberg ,  Michael Yeaman

发明人： John Edwards ,  Scott Filler ,  Donald Sheppard ,  Ashraf Ibrahim ,  Yue Fu ,  Brad Spellberg ,  Michael Yeaman

IPC分类号： A61K39/00 ,  C12N1/18

CPC分类号： A61K39/0002 ,  A61K38/00 ,  A61K39/00 ,  A61K2039/505 ,  C07K14/40 ,  C07K16/14

摘要： The invention provides a vaccine including an isolated Als protein family member having cell adhesion activity, or an immunogenic fragment thereof, with an adjuvant in a pharmaceutically acceptable medium. The invention also provides a method of treating or preventing disseminated candidiasis. The method includes administering an immunogenic amount of a vaccine an isolated Als protein family member having cell adhesion activity, or an immunogenic fragment thereof, in a pharmaceutically acceptable medium. A method of treating or preventing disseminated candidiasis also is provided that includes administering an effective amount of an isolated Als protein family member having cell adhesion activity, or an functional fragment thereof, to inhibit the binding or invasion of Candida to a host cell or tissue. The Als protein family member can be derived from a Candida strain selected from the group consisting of Candida albicans, Candida krusei, Candida tropicalis, Candida glabrata and Candida parapsilosis and the Als protein family member includes Als1p, Als3p, Als5p, Als6p, Als7p or Als9p.

摘要翻译： 本发明提供了包含具有细胞粘附活性的分离的Als蛋白家族成员或其免疫原性片段的疫苗，其在药学上可接受的培养基中与佐剂一起使用。 本发明还提供了治疗或预防弥漫性念珠菌病的方法。 该方法包括在药学上可接受的培养基中施用免疫原性量的具有细胞粘附活性的分离的Als蛋白家族成员或其免疫原性片段的疫苗。 还提供了治疗或预防弥漫性念珠菌病的方法，其包括施用有效量的具有细胞粘附活性的分离的Als蛋白家族成员或其功能片段，以抑制念珠菌与宿主细胞或组织的结合或侵入。 Als蛋白家族成员可以衍生自选自白色念珠菌，克罗斯假丝酵母，热带假丝酵母，光滑假丝酵母和副假丝酵母的念珠菌菌株，Als蛋白家族成员包括Als1p，Als3p，Als5p，Als6p，Als7p或Als9p 。

公开(公告)号：US20050246382A1

公开(公告)日：2005-11-03

申请号：US10836090

申请日：2004-04-30

申请人： John Edwards

发明人： John Edwards

IPC分类号： G06F17/30 ,  G06F7/00

CPC分类号： G06F17/30233 ,  G06F3/0604 ,  G06F3/061 ,  G06F3/0631 ,  G06F3/064 ,  G06F3/067 ,  G06F3/0689 ,  G06F17/30091 ,  Y10S707/99943 ,  Y10S707/99952 ,  Y10S707/99953 ,  Y10S707/99956

摘要： A write allocation technique extends a conventional write allocation procedure employed by a write anywhere file system of a storage system. A write allocator of the file system implements the extended write allocation technique in response to an event in the file system. The extended write allocation technique efficiently allocates blocks, and frees blocks, to and from a virtual volume (vvol) of an aggregate. The aggregate is a physical volume comprising one or more groups of disks, such as RAID groups, underlying one or more vvols of the storage system. The aggregate has its own physical volume block number (pvbn) space and maintains metadata, such as block allocation structures, within that pvbn space. Each vvol also has its own virtual volume block number (vvbn) space and maintains metadata, such as block allocation structures, within that vvbn space. The inventive technique extends input/output efficiencies of the conventional write allocation procedure to comport with an extended file system layout of the storage system.

摘要翻译： 写分配技术扩展了存储系统的写任意文件系统所采用的常规写分配过程。 文件系统的写分配器响应于文件系统中的事件实现扩展写分配技术。 扩展写分配技术有效地分配块，并将块从聚合体的虚拟卷（vvol）中分离出来。 聚合是包含一组或多组磁盘的物理卷，例如RAID组，存储系统的一个或多个vvol。 聚合具有自己的物理卷块数（pvbn）空间，并在该pvbn空间内维护诸如块分配结构的元数据。 每个vvol还具有自己的虚拟卷块号（vvbn）空间，并在该vvbn空间内维护诸如块分配结构的元数据。 本发明的技术扩展了常规写入分配过程的输入/输出效率，以与存储系统的扩展文件系统布局相匹配。

公开(公告)号：US20050217848A1

公开(公告)日：2005-10-06

申请号：US10511996

申请日：2003-04-10

申请人： John Edwards ,  Philippe Gambier ,  Vincent Tourillon ,  Christian Chouzenoux

发明人： John Edwards ,  Philippe Gambier ,  Vincent Tourillon ,  Christian Chouzenoux

IPC分类号： E21B47/01 ,  E21B47/06 ,  E21B49/10 ,  E21B43/00

CPC分类号： E21B49/10 ,  E21B47/01 ,  E21B47/06

摘要： A method of installing a sensor located in a chamber on the out-side of a casing, comprising the steps of positioning the casing in a well, cementing the casing in position, positioning a drilling tool inside the casing level with the chamber, drilling through the casing, chamber and cement into the formation surrounding the well so as to create a fluid communication path, and sealing the hole drilled in the casing.

摘要翻译： 一种安装位于壳体外侧的室内的传感器的方法，包括以下步骤：将壳体定位在井中，将壳体固定在适当位置，将钻具在壳体内与腔室定位，钻穿 壳体，腔室和水泥进入围绕井的地层，以便产生流体连通路径，并且密封在壳体中钻出的孔。

公开(公告)号：US20050121005A1

公开(公告)日：2005-06-09

申请号：US10505657

申请日：2003-03-07

申请人： John Edwards

发明人： John Edwards

IPC分类号： F02M21/02 ,  F02D19/02 ,  F02D19/08 ,  F02D41/00 ,  F02D41/24 ,  F02D41/26 ,  F02M41/00

CPC分类号： F02D41/26 ,  F02B2201/06 ,  F02D19/0631 ,  F02D19/105 ,  F02D41/0027 ,  F02D41/2422 ,  Y02T10/36

摘要： A gas substitution system for a dual fuel diesel engine which monitors load and RPM and the operational state of the engine and vehicle including throttle displacement, cruise control, idle, wheel and engine braking, manual control. Data is collected to establish parameters such as fuel consumption and exhaust emissions for load/RPM pair values and using these to create a table of optimum gas substitution values at each load RPM pair within the range of operational states within which substitution is viable. The system is applicable to: constant engine speed stationary applications (gensets); variable engine speed applications, including mobile plant; automative applications with no existing engine management system; automative applications with a basic existing engine management system; automative applications with an advanced existing engine management system.

摘要翻译： 一种双燃料柴油发动机的气体替代系统，用于监测负载和RPM以及发动机和车辆的运行状态，包括节气门位移，巡航控制，空转，车轮和发动机制动，手动控制。 收集数据以建立诸如燃料消耗和负载/ RPM对值的废气排放之类的参数，并使用这些参数来创建在替代可行的操作状态范围内的每个负载RPM对处的最佳气体替代值的表。 该系统适用于：恒定发动机转速固定应用（发电机组）; 可变发动机速度应用，包括移动工厂; 没有现有发动机管理系统的自动应用; 具有基本现有发动机管理系统的自动应用; 具有先进现有发动机管理系统的自动化应用。

公开(公告)号：US20050054821A1

公开(公告)日：2005-03-10

申请号：US10486234

申请日：2002-06-08

申请人： John Gatehouse ,  Elaine Fitches ,  John Edwards

发明人： John Gatehouse ,  Elaine Fitches ,  John Edwards

IPC分类号： A01N63/02 ,  C07K14/42 ,  C12N15/82 ,  C07K1/00 ,  C07K14/00 ,  C07K17/00

CPC分类号： C07K14/42 ,  A01N63/02 ,  C07K2319/00 ,  C12N15/8286 ,  Y02A40/162

摘要： A fusion protein comprising a translocating moiety and a toxic moiety wherein the translocating moiety comprises a plant protein that is capable of acting as a carrier to translocate the toxic moiety across the gut wall of at least one plant pathogen, wherein the toxic moiety is adapted to be effective as a toxic agent following translocation; composition comprising the protein, methods for preparation thereof; polynucleotide encoding the fusion protein, vector comprising the polynucleotide, host cell and transgenic plant cell or plant that is resistant to pathogen, expressing the fusion protein, and uses thereof in combatting plant pathogens and in insect control.

摘要翻译： 包含易位部分和毒性部分的融合蛋白，其中所述易位部分包含能够作为载体转移至少一种植物病原体的肠壁上的毒性部分的载体的植物蛋白，其中所述毒性部分适于 作为易位后的有毒药物有效; 包含蛋白质的组合物，其制备方法; 编码融合蛋白的多核苷酸，包含表达融合蛋白的对病原体具有抗性的多核苷酸，宿主细胞和转基因植物细胞或植物的载体，及其用于对抗植物病原体和昆虫控制的用途。

公开(公告)号：US6065218A

公开(公告)日：2000-05-23

申请号：US532207

申请日：1995-09-22

申请人： John Edwards

发明人： John Edwards

IPC分类号： E21B47/00 ,  E21B47/01 ,  E21B47/08 ,  G01B5/12

CPC分类号： E21B47/00 ,  E21B47/01

摘要： The invention relates to a logging method and apparatus adapted for use in non-circular boreholes which, in one embodiment, comprises the use of a first and a second sonde, each sonde having: a pad adapted for contact with the borehole wall, at least a sensor on each pad, and an extendable arm for keeping the pad against the wall of the borehole. The first and second sonde produce measurements related to the same property of the formations, and the first and the second sonde are connected so as to keep the pads aligned with a 90.degree. azimuthal spacing therebetween.

摘要翻译： 本发明涉及一种适用于非圆形钻孔的测井方法和装置，在一个实施例中，该方法和装置包括使用第一和第二探头，每个探空器具有：适于与井眼壁接触的垫，至少 每个垫上的传感器，以及用于将垫保持在井眼的壁上的可延伸臂。 第一和第二探头产生与地层相同属性相关的测量，并且连接第一和第二探测器，以便使垫保持90°方位角间隔。

公开(公告)号：US5813196A

公开(公告)日：1998-09-29

申请号：US586031

申请日：1996-01-16

申请人： Serge Page ,  Guy Champagne ,  Dave Roberts ,  John Edwards

发明人： Serge Page ,  Guy Champagne ,  Dave Roberts ,  John Edwards

IPC分类号： B65B5/06 ,  B65B35/30

CPC分类号： B65B5/067 ,  B65B5/061

摘要： A method and a machine for automatically bagging articles in a bag and in a sequential and uninterrupted manner. A plurality of articles are continuously fed to the machine and received in two or three compartments, herein three compartments. Once the third article is received in the third compartment, all three articles are discharged within a bag held under the machine. A control circuit, after a predetermined time delay actuates an article support element which is caused to enter into the third compartment or the first compartment depending on the sequence of loading the machine whereby to support a fourth article entering the third compartment due to the fact that the bottom end of all compartments is open. The feeding device is uninterrupted and continues to feed articles to the machine regardless if the bottom discharge gate is open and the sequence is automatically reversed, back and forth, between the first and third and third and first compartments.

摘要翻译： 一种用于在袋中自动包装物品并以连续且不间断的方式的机器。 多个制品被连续地供给到机器中并且被接纳在两个或三个隔室中，这里是三个隔间。 一旦第三个物品被收纳在第三个隔间中，所有三个物品都放在机器下方的袋子内。 在预定的时间延迟之后，控制电路根据加载机器的顺序致动物品支撑元件，该物品支撑元件进入第三隔间或第一隔间，由此支撑进入第三隔室的第四物品，因为以下事实： 所有隔间的底端是开放的。 无论底部排放门是否打开，并且序列在第一和第三和第三和第一隔室之间来回自动地进行，进料设备不间断，并且继续将物品送入机器。

公开(公告)号：US5782344A

公开(公告)日：1998-07-21

申请号：US806126

申请日：1997-02-28

申请人： John Edwards ,  Raymond L. Larson

发明人： John Edwards ,  Raymond L. Larson

IPC分类号： B65B9/20 ,  B65B31/00 ,  B65B61/20 ,  B65D77/28

CPC分类号： B65B9/2028 ,  B65B31/00 ,  B65B61/205 ,  B65B9/2042 ,  B65D77/283

摘要： A liquid product carrying plastic film pouch (10) having a straw (12) free-floating in the liquid product (11) is described. The liquid product (11) contained within the inner chamber (13) of the pouch occupies from about 60% to about 90% of the volume of the inner chamber (13) of the pouch and a portion of air from the remaining volume is evacuated in sufficient quantity to permit the side walls (14,15) of the pouch to be collapsed against one another when the pouch is grasped by the hand of a user person. By collapsing the side walls (14,15) together the straw (12) located within the liquid can be grasped and manipulated to puncture the plastic film pouch (1) to extend a portion (12') of the straw (12) exteriorly of the pouch whereby to extract liquid therefrom. The pouch (10) is made of a multilayer resin film having an inner sealant layer (26) formed of a linear low density ethylene-octene copolymer or very low density ethylene copolymer (octene or other copolymers) such that when the straw punctures the film, the inner sealant layer (26) forms a membrane about the straw which exhibits a self-sealing behavior so as to prevent leakage in the punctured region as liquid is extracted from the pouch (10) through the straw (12).

摘要翻译： 描述了具有自由浮动在液体产品（11）中的吸管（12）的携带塑料膜袋（10）的液体产品。 容纳在袋的内室（13）内的液体产品（11）占袋的内室（13）的体积的约60％至约90％，并且将来自剩余容积的空气的一部分抽真空 足够的量使得袋子的侧壁（14,15）在使用者的手握住袋时彼此折叠。 通过将侧壁（14,15）折叠在一起，位于液体内的吸管（12）可以被抓住并操作以刺穿塑料膜袋（1），以将吸管（12'）的一部分（12'）延伸到 该袋从其中提取液体。 袋（10）由具有由线性低密度乙烯 - 辛烯共聚物或非常低密度乙烯共聚物（辛烯或其它共聚物）形成的内部密封剂层（26）的多层树脂膜制成，使得当秸秆穿透膜 内部密封剂层（26）形成围绕吸管的膜，其具有自密封性能，以便当液体通过吸管（12）从袋（10）中提取时，防止在穿孔区域中的泄漏。