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110 条记录 (耗时 0.064 秒)

    HIGH ENERGY RADIATION INSENSITIVE ANALYTE SENSORS
    81.
    发明申请
    HIGH ENERGY RADIATION INSENSITIVE ANALYTE SENSORS 有权
    高能辐射敏感分析仪传感器

    公开(公告)号：US20130189720A1

    公开(公告)日：2013-07-25

    申请号：US13580628

    申请日：2011-03-10

    申请人： James R. Petisce

    发明人： James R. Petisce

    IPC分类号： C12Q1/26 ,  G01N27/327

    CPC分类号： C12Q1/26 ,  A61B5/14865 ,  A61B2562/18 ,  G01N27/327

    摘要： Enzyme based analyte sensors having radiation stabilizing agents are disclosed and described. More particularly, devices comprising a radiation stabilizing agent and methods for stabilizing sensors to high energy radiation sterilization are disclosed and described.

    摘要翻译： 公开和描述了具有辐射稳定剂的基于酶的分析物传感器。 更具体地，公开和描述了包括辐射稳定剂的装置和用于将传感器稳定到高能辐射灭菌的方法。

    Calibrant infusion fluid source preparation
    82.
    发明授权
    Calibrant infusion fluid source preparation 有权
    校准液输液制备

    公开(公告)号：US08438898B2

    公开(公告)日：2013-05-14

    申请号：US12827802

    申请日：2010-06-30

    申请人： James R. Petisce ,  Michael J. Higgins ,  Kristie Trinh ,  Todd Abraham

    发明人： James R. Petisce ,  Michael J. Higgins ,  Kristie Trinh ,  Todd Abraham

    IPC分类号： G01N31/22 ,  G01N33/66 ,  G01N33/96

    CPC分类号： G01N33/96 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/4839 ,  A61M2207/00 ,  A61M2230/201 ,  Y10T436/10 ,  Y10T436/102499 ,  Y10T436/104998 ,  Y10T436/108331

    摘要： Methods and systems for preparation of calibrant infusion fluid sources are disclosed. In one embodiment, a precise volume of glucose is injected into a saline-solution filled calibrant infusion fluid source proximate in time to conducting a calibration procedure. The glucose concentration in the calibrant infusion fluid source is subsequently calculated based on the measured weight of the saline-solution, as determined prior to glucose injection, and the volume of glucose injected. This method provides a highly accurate and convenient manner for use in a hospital environment, for example, with an intravenous blood glucose sensor system. In another embodiment, a premixed calibrant infusion fluid source is provided that includes saline solution and a predetermined concentration of glucose. In such embodiments, shelf life problems related to water evaporation are mitigated by hermetically covering or otherwise hermetically containing the calibrant infusion fluid source up until the point of use.

    摘要翻译： 公开了用于制备校准液输注液源的方法和系统。 在一个实施方案中，在时间上将精确体积的葡萄糖注入盐水溶液填充的校准液输注液源中以进行校准程序。 随后根据在注射葡萄糖之前测定的盐水溶液的测量重量和注入的葡萄糖体积来计算校准液输注液源中的葡萄糖浓度。 该方法提供了在医院环境中使用的高度准确和方便的方式，例如使用静脉内血糖传感器系统。 在另一个实施方案中，提供了预混合的校准液输注液源，其包括盐溶液和预定浓度的葡萄糖。 在这样的实施方案中，通过气密地覆盖或以其他方式密封含有校准液输注流体源直到使用点来减轻与水蒸发相关的保质期问题。

    ANALYTE SENSOR LAYERS AND METHODS RELATED THERETO
    83.
    发明申请
    ANALYTE SENSOR LAYERS AND METHODS RELATED THERETO 审中-公开
    分析传感器层及其相关方法

    公开(公告)号：US20120283537A1

    公开(公告)日：2012-11-08

    申请号：US13503745

    申请日：2010-10-28

    申请人： James R. Petisce ,  Henry W. Oviatt

    发明人： James R. Petisce ,  Henry W. Oviatt

    IPC分类号： A61B5/1473 ,  G01N27/28

    CPC分类号： A61B5/14865 ,  A61B5/14532 ,  A61B5/415 ,  C12Q1/002

    摘要： Sensors for measuring an analyte in a subject comprising at least one electrode having an electroactive surface, at least one interferent-reducing layer comprising vinyl ester monomeric units disposed distally from the electroactive surface, an enzyme layer disposed distally from the electroactive surface and a flux-limiting membrane disposed over the at least one interferent-reducing layer and the enzyme layer. Methods of measuring an analyte in a subject comprising providing the electrochemical analyte sensor, contacting a sample comprising an analyte and an interferent with the at least one interferent-reducing layer comprising vinyl ester monomeric units, and measuring the analyte, where the amount of interferent reaching the electroactive surface is reduced.

    摘要翻译： 用于测量受试者中的分析物的传感器，包括至少一个具有电活性表面的电极，至少一个包含从电活性表面向远侧设置的乙烯基酯单体单元的干扰物减少层，远离电活性表面设置的酶层， 设置在至少一个干扰物还原层和酶层上的限制膜。 测量受试者中的分析物的方法，包括提供电化学分析物传感器，使包含分析物的样品和与包含乙烯基酯单体单元的至少一个干扰物降低层的干扰物接触，并测量分析物，其中干扰物达到的量 电活性表面减少。

    Membrane Layer for Electrochemical Biosensor and Method of Accommodating Electromagnetic and Radiofrequency Fields
    85.
    发明申请
    Membrane Layer for Electrochemical Biosensor and Method of Accommodating Electromagnetic and Radiofrequency Fields 审中-公开
    电化学生物传感器膜层和容纳电磁场和射频场的方法

    公开(公告)号：US20100160756A1

    公开(公告)日：2010-06-24

    申请号：US12636117

    申请日：2009-12-11

    申请人： James R. Petisce ,  Henry W. Oviatt

    发明人： James R. Petisce ,  Henry W. Oviatt

    IPC分类号： A61B5/1468 ,  A61B18/18

    CPC分类号： C12Q1/002 ,  A61B5/14532 ,  A61B5/14542 ,  A61B5/14865 ,  A61B5/415

    摘要： A method comprising providing an in vivo electrochemical biosensor, the biosensor comprising an electrode surface, a flux-limiting layer covering at least a portion of the electrode surface, covering at least a portion of the flux-limiting layer with a hydrophilic polymer membrane, and preventing or eliminating disruption of the output signal of the electrochemical biosensor by an external EMF or external RF source during in vivo use of the biosensor in a subject.

    摘要翻译： 一种包括提供体内电化学生物传感器的方法，所述生物传感器包括电极表面，覆盖所述电极表面的至少一部分的磁通限制层，用亲水性聚合物膜覆盖所述限流层的至少一部分，以及 在对象体内使用生物传感器时，防止或消除外部EMF或外部RF源对电化学生物传感器的输出信号的破坏。

    Method for increasing adhesion between a coating and an optical glass fiber electron beam pretreatment
    90.
    发明授权
    Method for increasing adhesion between a coating and an optical glass fiber electron beam pretreatment 失效
    增加涂层与光学玻璃纤维电子束预处理之间粘附性的方法

    公开(公告)号：US5812725A

    公开(公告)日：1998-09-22

    申请号：US826388

    申请日：1997-04-09

    申请人： James R. Petisce

    发明人： James R. Petisce

    IPC分类号： C03C25/10 ,  B01J19/08 ,  C03C25/12 ,  C03C25/62 ,  G02B6/44 ,  G02B6/16 ,  B05D5/06 ,  C03B37/01

    CPC分类号： C03C25/12 ,  B01J19/085 ,  C03C25/6266

    摘要： This invention provides a method of increasing adhesion of radiation-cured, inner primary coatings on glass optical fibers. A glass optical fiber drawing tower has a controllable variable amperage electron beam for exposing different sections of a glass optical fiber with different amperage levels of electron beam radiation. The different sections of the glass optical fiber after being exposed to the selected amperage levels of electron beam radiation are then coated with an inner primary coating composition which is finally cured by exposure to actinic radiation. Later formed sections of the same glass optical fiber can be exposed to different amperage levels of electron beam radiation and then coated and cured. The different sections of the glass optical fiber which have been coated with an inner primary coating using this method demonstrate correspondingly different degrees of coating adhesion. Reduced levels of adhesion promoter are required for inner primary coating compositions when using this method.

    摘要翻译： 本发明提供了一种增加辐射固化的内部初级涂层对玻璃光纤的附着力的方法。 玻璃光纤拉伸塔具有可控的可变安培电子束，用于暴露具有不同安培数电子束辐射的玻璃光纤的不同部分。 然后将玻璃光纤暴露于所选安培数电子束辐射后的不同部分用内部初级涂层组合物涂覆，该内部初级涂层组合物最终通过暴露于光化辐射而固化。 后来，同一玻璃光纤的成形部分可以暴露于不同电流强度的电子束辐射，然后涂覆和固化。 使用这种方法涂覆有内部初级涂层的玻璃光纤的不同部分表现出相应的不同程度的涂层附着力。 使用该方法时，内部初级涂料组合物需要降低粘合促进剂的含量。