公开(公告)号：US09880528B2

公开(公告)日：2018-01-30

申请号：US13972803

申请日：2013-08-21

Applicant: MEDTRONIC MINIMED, INC.

Inventor： John J. Mastrototaro ,  Desmond Barry Keenan ,  Benyamin Grosman ,  Neha J. Parikh ,  Anirban Roy ,  Do Kim

IPC: G05B15/02 ,  G06F19/00

CPC classification number: G05B15/02 ,  G06F19/00 ,  G06F19/3468 ,  G16H20/17

Abstract: Apparatus are provided for medical devices and related operating systems and methods. An exemplary medical device includes a motor, one or more data storage elements to maintain control information, and a control module coupled to the motor and the one or more data storage elements. The control module is configured to obtain updated control information via a peer-to-peer communication session over a network, store the updated control information in the one or more data storage elements, and thereafter operate the motor based at least in part on the updated control information.

公开(公告)号：US09861748B2

公开(公告)日：2018-01-09

申请号：US14174487

申请日：2014-02-06

Applicant: MEDTRONIC MINIMED, INC.

Inventor： John J. Mastrototaro ,  Desmond Barry Keenan ,  Benyamin Grosman ,  Anirban Roy

IPC: A61M5/172 ,  A61M5/145 ,  A61M5/142

CPC classification number: A61M5/1723 ,  A61M5/14248 ,  A61M5/1452 ,  A61M2005/14208 ,  A61M2205/18 ,  A61M2205/3365 ,  A61M2205/3569 ,  A61M2205/3592 ,  A61M2205/70 ,  A61M2205/702 ,  A61M2205/8212

Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device capable of delivering fluid to a user involves storing alert configuration information for the user, identifying an alert condition while operating the infusion device to deliver the fluid based at least in part on the alert configuration information for the user, and in response to identifying the alert condition, providing a user notification in accordance with the user's stored alert configuration information.

公开(公告)号：US09849239B2

公开(公告)日：2017-12-26

申请号：US13966120

申请日：2013-08-13

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Benyamin Grosman ,  Neha J. Parikh ,  Anirban Roy ,  Desmond Barry Keenan ,  John J. Mastrototaro

IPC: A61M5/172 ,  A61B5/145 ,  A61B5/00 ,  G06F19/00

CPC classification number: A61M5/1723 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/4839 ,  G06F19/3468

Abstract: A controller for an insulin infusion device includes a processor device and a memory element that cooperate to provide a processor-implemented closed-loop insulin limit module. The insulin limit module is operated to obtain: a fasting blood glucose value of a user; a total daily insulin value of the user; and fasting insulin delivery data that is indicative of insulin delivered to the user during a fasting period. The insulin limit module calculates a maximum insulin infusion rate for the user based on the fasting blood glucose value, the total daily insulin value, and the fasting insulin delivery data. The maximum insulin infusion rate is applicable during a period of closed-loop operation of the insulin infusion device.

公开(公告)号：US09750878B2

公开(公告)日：2017-09-05

申请号：US14103522

申请日：2013-12-11

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Anirban Roy ,  Desmond Barry Keenan ,  Paul H. Kovelman

IPC: A61M5/172 ,  A61B5/145 ,  A61B5/00 ,  G06F19/00 ,  A61M5/142

CPC classification number: A61M5/1723 ,  A61B5/14532 ,  A61B5/4839 ,  A61B5/6849 ,  A61B5/7275 ,  A61M5/14244 ,  A61M2205/33 ,  A61M2205/50 ,  A61M2230/201 ,  G06F19/00 ,  G06F19/3468

Abstract: Presented here are techniques for controlling glucose levels of a patient based on predicted time to a target glucose level. One methodology predicts a trajectory of the blood glucose level based on past observations of the blood glucose level, determines a cost expression based on the trajectory, and affects a future command to an infusion pump to affect a cost value according to the cost expression. Another methodology defines a target blood glucose concentration level for the patient, observes a current blood glucose concentration for the patient based on signals received from a blood-glucose sensor, and predicts a duration of time for the patient's blood glucose concentration to reach the target blood glucose concentration level based on the observed current blood glucose concentration.

公开(公告)号：US09662445B2

公开(公告)日：2017-05-30

申请号：US13966114

申请日：2013-08-13

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Neha J. Parikh ,  Anirban Roy ,  Desmond Barry Keenan ,  John J. Mastrototaro ,  Benyamin Grosman

IPC: A61M5/172 ,  A61B5/145 ,  A61B5/00

CPC classification number: A61M5/1723 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/4839

Abstract: An electronic controller for an insulin infusion device includes at least one processor device and at least one memory element that cooperate to provide a processor-implemented closed-loop initiation module. The initiation module is operated to obtain a most recent calibration factor for a continuous glucose sensor, the most recent calibration factor representing a first conversion value applicable to convert a first sensor value to a first blood glucose value. The initiation module also obtains a prior calibration factor for the sensor, and calibration timestamp data for the most recent calibration factor and the prior calibration factor. The initiation module regulates entry into a closed-loop operating mode of the insulin infusion device, based on the most recent calibration factor, the prior calibration factor, and the calibration timestamp data.

公开(公告)号：US09579066B2

公开(公告)日：2017-02-28

申请号：US14539855

申请日：2014-11-12

Applicant: Medtronic MiniMed, Inc.

Inventor： Rebecca K. Gottlieb ,  Ying Luo ,  Raghavendhar Gautham ,  Bradley Liang ,  Anirban Roy ,  Kenneth W. Cooper ,  Rajiv Shah ,  Barry Keenan

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1495 ,  A61M5/172

CPC classification number: A61B5/7221 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/1473 ,  A61B5/1495 ,  A61B5/4839 ,  A61B5/6849 ,  A61B5/7275 ,  A61B5/743 ,  A61M5/1723 ,  A61M2005/1726 ,  A61M2205/3303 ,  A61M2230/201

Abstract: Disclosed are a system and method for determining a metric and/or indicator of a reliability of a blood glucose sensor in providing glucose measurements. In one aspect, the metric and/or indicator may be computed based, at least in part, on an observed trend associated with signals generated by the blood glucose sensor.

Abstract translation: 公开了一种用于在提供葡萄糖测量中确定血糖传感器的可靠性的度量和/或指标的系统和方法。 在一个方面，可以至少部分地基于与由血糖传感器产生的信号相关联的观察趋势来计算度量和/或指示符。

公开(公告)号：US20170049961A1

公开(公告)日：2017-02-23

申请号：US15096142

申请日：2016-04-11

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Anirban Roy

IPC: A61M5/172 ,  A61M5/145

CPC classification number: A61M5/1723 ,  A61M5/1452 ,  A61M2005/14208 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/702 ,  A61M2230/005 ,  A61M2230/201

Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device to deliver a bolus amount of fluid influencing a physiological condition in a body of a user involves identifying, based on measurement values for the physiological condition, a residual value for the physiological condition resulting from the bolus amount of the fluid and determining an updated ratio for a subsequent bolus by adjusting an initial ratio influencing the bolus amount to compensate for the residual value. The updated ratio may be stored in a data storage element for use in determining a subsequent bolus amount in lieu of the initial ratio value.

Abstract translation: 提供输液系统，输液装置和相关操作方法。 操作输注装置以输送影响使用者身体中的生理状况的大量液体的示例性方法包括基于生理状况的测量值来识别由推注量的生理状况产生的残留值 流体，并通过调整影响推注量的初始比例来确定后续推注的更新比例，以补偿残余值。 更新的比率可以存储在数据存储元件中，以用于确定替代初始比值的后续推注量。

公开(公告)号：US20160296693A1

公开(公告)日：2016-10-13

申请号：US15188836

申请日：2016-06-21

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Desmond Barry Keenan ,  John J. Mastrototaro ,  Benyamin Grosman ,  Anirban Roy

IPC: A61M5/142 ,  A61M5/145 ,  A61M5/172

CPC classification number: A61M5/14248 ,  A61M5/1452 ,  A61M5/1723 ,  A61M2005/14208 ,  A61M2205/18 ,  A61M2205/3365 ,  A61M2205/3569 ,  A61M2205/3592 ,  A61M2205/70 ,  A61M2205/702 ,  A61M2205/8212 ,  A61M2230/06 ,  A61M2230/201

Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device capable of delivering fluid to a user involves identifying a condition of the user that is likely to influence a response to the fluid in the body of the user and classifying the condition as a first type of a plurality of types of conditions. After classifying the condition as the first type, the method continues by adjusting control information for operating the infusion device based on the first type and operating the infusion device to deliver the fluid to the user in accordance with the adjusted control information.

公开(公告)号：US20160256629A1

公开(公告)日：2016-09-08

申请号：US15138540

申请日：2016-04-26

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Benyamin Grosman ,  Di Wu ,  Anirban Roy ,  Neha J. Parikh

IPC: A61M5/172 ,  G06F19/00 ,  A61B5/145 ,  A61M5/142 ,  A61B5/00

CPC classification number: A61M5/1723 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/4839 ,  A61B5/746 ,  A61M5/14244 ,  A61M2005/14208 ,  A61M2205/52 ,  A61M2230/005 ,  A61M2230/201 ,  G06F19/00 ,  G06F19/3468 ,  G16H20/17

Abstract: An insulin infusion device includes a processor architecture, and a memory element that stores executable instructions to perform a method of controlling delivery of insulin to a user. The method operates the device in a closed-loop mode to deliver insulin, obtains patient-specific parameters for a current time sample, and estimates a plasma insulin value and a blood glucose value for the user based on at least some of the patient-specific parameters. The estimating is also based on a previously estimated plasma insulin value obtained for a previous time sample, and a previously estimated blood glucose value obtained for the previous time sample. A predicted sensor glucose value is generated for the current time sample, and the closed-loop mode or a safe basal mode is selected for controlling operation of the insulin infusion device in accordance with the selected mode.

Abstract translation: 胰岛素输注装置包括处理器架构和存储可执行指令的存储器元件，以执行控制向用户传送胰岛素的方法。 所述方法以闭环模式操作所述装置以递送胰岛素，获取当前时间样本的患者特异性参数，并且基于所述患者特异性的至少一些来估计用户的血浆胰岛素值和血糖值 参数。 估计还基于对于先前时间样本获得的先前估计的血浆胰岛素值和对于先前时间样本获得的先前估计的血糖值。 为当前时间样本生成预测的传感器葡萄糖值，并且根据所选择的模式选择闭环模式或安全基础模式以控制胰岛素输注装置的操作。

公开(公告)号：US20150217051A1

公开(公告)日：2015-08-06

申请号：US14174487

申请日：2014-02-06

Applicant: MEDTRONIC MINIMED, INC.

Inventor： John J. Mastrototaro ,  Desmond Barry Keenan ,  Benyamin Grosman ,  Anirban Roy

IPC: A61M5/172

CPC classification number: A61M5/1723 ,  A61M5/14248 ,  A61M5/1452 ,  A61M2005/14208 ,  A61M2205/18 ,  A61M2205/3365 ,  A61M2205/3569 ,  A61M2205/3592 ,  A61M2205/70 ,  A61M2205/702 ,  A61M2205/8212

Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device capable of delivering fluid to a user involves storing alert configuration information for the user, identifying an alert condition while operating the infusion device to deliver the fluid based at least in part on the alert configuration information for the user, and in response to identifying the alert condition, providing a user notification in accordance with the user's stored alert configuration information.

Abstract translation: 提供输液系统，输液装置和相关操作方法。 操作能够向用户输送流体的输注装置的示例性方法包括存储用户的警报配置信息，至少部分地基于用户的警报配置信息来操作输注装置以运送输液装置以输送流体，识别警报状况 并且响应于识别警报状况，根据用户存储的警报配置信息提供用户通知。