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81.发明授权Physician's programmer for implantable devices having cardiac diagnostic and patient alerting capabilities 有权具有心脏诊断和患者警报能力的可植入装置的医师程序员公开(公告)号：US07801596B2
公开(公告)日：2010-09-21
申请号：US11130110
申请日：2005-05-17
IPC分类号： A61B5/0452
CPC分类号： A61N1/37247 , A61N1/36557
摘要： A programmer is provided for an implantable medical device capable of detecting cardiac events in a human patient. The programmer has a two-way wireless data communication mechanism with the implantable medical device and a graphical user interface is included which has a display and input mechanism designed for use in programming patient specific parameters for the detection of ST shift related cardiac events.
摘要翻译： 提供了一种能够检测人类患者心脏事件的可植入医疗装置的编程器。 程序员具有可植入医疗装置的双向无线数据通信机制，并且包括图形用户界面，其具有设计用于编程患者特定参数以用于检测ST移位相关心脏事件的显示和输入机制。
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公开(公告)号：US20130184735A1
公开(公告)日：2013-07-18
申请号：US13349060
申请日：2012-01-12
IPC分类号： A61M29/00
CPC分类号： A61M29/00 , A61M25/0662 , A61M2025/0183 , A61M2025/0188 , A61M2025/0681
摘要： Dilators and sheaths for use in minimally invasive vascular therapy are disclosed. In some embodiments, the dilators include a slot that accesses a guidewire lumen within the dilator. These slots facilitate rapid exchange of one dilator for another. In another embodiment, a dilator is sufficiently stiff to facilitate entry, but also designed to facilitate placement of the dilator along a tortuous path.
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公开(公告)号：US5484425A
公开(公告)日：1996-01-16
申请号：US321806
申请日：1994-10-12
IPC分类号： A61M25/00 , A61M25/06 , A61M25/098
CPC分类号： A61M25/0662 , A61M25/005 , A61M25/0054 , A61M2025/0081 , A61M25/0053
摘要： This invention provides a non-kinking and thin-walled introducer sheath (10) having a flat wire metal coil (12) that lies within a plastic covering (20) fitted onto the exterior surface of the flat wire metal coil (12) and extends into a space between adjacent turns of the flat wire metal coil (12) without covering the interior surface. Each turn of the flat wire metal coil (12) has a thickness within the range between 0.75-3.0 mils with a width to thickness ratio lying between 12 and 80. A plastic adapter (30) is provided and is located at a proximal end of the sheath (10) for inserting guide wires through the sheath (10) into a vessel.
摘要翻译： 本发明提供一种具有扁平线金属线圈（12）的非扭结和薄壁引导器护套（10），该扁平线金属线圈（12）位于安装在扁平线金属线圈（12）的外表面上的塑料覆盖物（20）内并延伸 进入扁平线金属线圈（12）的相邻匝之间的空间，而不覆盖内表面。 扁平线金属线圈（12）的每一圈的厚度在0.75-3.0密耳之间的范围内，宽度与厚度之比位于12和80之间。提供塑料适配器（30）并且位于 所述护套（10）用于将引导线穿过所述护套（10）插入容器中。
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84.发明授权Use of a stent with the capability to inhibit malignant growth in a vessel such as a biliary duct 失效使用具有抑制诸如胆管的血管中恶性生长能力的支架
公开(公告)号：US5176617A
公开(公告)日：1993-01-05
申请号：US779641
申请日：1991-10-21
IPC分类号： A61B19/00 , A61F2/00 , A61F2/82 , A61F2/88 , A61K51/12 , A61L31/14 , A61L31/16 , A61M36/12 , A61N5/10
CPC分类号： A61F2/88 , A61F2/0077 , A61F2/82 , A61K51/1282 , A61L31/14 , A61L31/16 , A61N5/1002 , A61F2210/0095 , A61L2300/416 , A61L2300/44 , A61N2005/1089
摘要： It is well known that radiation therapy can reduce the proliferation of rapidly growing cancer cells is a malignant tumor. The present invention utilizes a radioisotope which is integral to a stent which can irradiate the tissue in close proximity to the implantation site of the stent in order to reduce the rapid growth of malignant cells in a vessel, such as a bile duct while simultaneously maintaining vessel patency. The radioisotope could be place inside the stent, alloyed into the metal from which the stent is made, or preferably, it can be coated onto the stent's exterior surface.
摘要翻译： 众所周知，放射治疗可以减少快速生长的癌细胞的增殖是恶性肿瘤。 本发明利用放射性同位素，该放射性同位素可以在靠近支架植入部位照射组织的支架上成一体，以便减少容器如胆管中的恶性细胞的快速生长，同时保持血管 通畅 放射性同位素可以放置在支架内，合金化成制造支架的金属，或者优选地，其可以涂覆在支架的外表面上。
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公开(公告)号：US4765332A
公开(公告)日：1988-08-23
申请号：US885139
申请日：1986-07-14
CPC分类号： A61B17/32075 , A61B2017/22038
摘要： An atherectomy apparatus and method is disclosed for the purpose of surgical excision of atheromas which typically consist of plaque deposits that cause narrowing (stenosis) of an artery. The apparatus, called a pullback atherectomy catheter, cuts and collects obstructive material into a collection chamber as the catheter is pulled back through obstructive material within a human vessel such as an artery.
摘要翻译： 公开了用于手术切除动脉粥样化的目的的粥样斑块切除装置和方法，其通常由导致动脉狭窄（狭窄）的斑块沉积物组成。 被称为回拉式动脉粥样硬化斑块切除术导管的装置在导管通过诸如动脉之类的人容器内的阻塞物质被拉回时将切割并收集阻塞物质到收集室中。
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86.发明授权Expandable catheter system for fluid injection into and deep to the wall of a blood vessel 有权可扩张导管系统，用于注入血管壁并深入血管壁公开(公告)号：US09056185B2
公开(公告)日：2015-06-16
申请号：US13342521
申请日：2012-01-03
申请人： David R. Fischell , Tim A. Fischell
发明人： David R. Fischell , Tim A. Fischell
CPC分类号： A61M5/46 , A61B5/6848 , A61M25/0026 , A61M25/0084 , A61M25/0097 , A61M25/0662 , A61M2025/0039 , A61M2025/0085 , A61M2025/0086 , A61M2025/0681 , A61M2202/0007 , A61M2205/0266 , A61M2210/12
摘要： A catheter-based/intravascular fluid injection system with application to renal denervation includes a multiplicity of needles which expand open around a central axis to engage the wall of a blood vessel, or the wall of the left atrium, allowing the injection of a cytotoxic and/or neurotoxic solution for ablating conducting tissue, or nerve fibers around the ostium of the pulmonary vein, or circumferentially in or just beyond the outer layer of the renal artery. The expandable delivery system includes expandable components that facilitate positioning of a multiplicity of injection needles against the inside wall of a blood vessel from where they can be advanced. The system also includes means to limit and/or adjust the depth of penetration of the ablative fluid into the tissue of the wall of the targeted blood vessel.
摘要翻译： 应用于肾去神经支配的基于导管的/血管内流体注射系统包括多个针，其围绕中心轴线敞开，以与血管的壁或左心房的壁接合，允许注射细胞毒性和 或用于烧蚀导管组织的神经毒性溶液，或肺静脉口周围的神经纤维，或在肾动脉的外层周围或周边。 可扩展递送系统包括可扩展部件，其有助于将多个注射针定位在血管的内壁上，从而可以将其推进。 该系统还包括限制和/或调节烧蚀液体渗透到目标血管壁的组织中的深度的装置。
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公开(公告)号：US4699615A
公开(公告)日：1987-10-13
申请号：US796409
申请日：1985-11-08
申请人： David R. Fischell , Tim A. Fischell
发明人： David R. Fischell , Tim A. Fischell
CPC分类号： A61M5/16877 , A61M5/1424 , A61M2005/14264 , Y10S128/12
摘要： A Finger Actuated Medication Infusion System (FAMIS) for delivering a dosage of medication into a living body. The FAMIS is fully mechanical and comprises a reservoir, a pump and connecting catheters. The reservoir includes a sealed bellows portion which contains a pressurant and exerts a substantially constant pressure on the medication in the reservoir, regardless of the amount of medication therein. The pump includes a bellows assembly disposed within an equalizing pressure chamber, and will deliver medication through the bellows assembly at a predetermined flow rate independent of ambient temperature, ambient pressure or the amount of medication remaining in the reservoir. The FAMIS design also provides safeguards against inadvertant overdosing, transmission of bacteria into the body and prevents gas bubbles within the reservoir from impeding the flow of medication through an outlet flow restrictor which forms part of the FAMIS pump.
摘要翻译： 手指致动药物输注系统（FAMIS），用于将一定剂量的药物输送到活体内。 FAMIS是完全机械的，包括一个储存器，一个泵和连接导管。 储存器包括密封的波纹管部分，其包含加压剂并对储存器中的药物施加基本恒定的压力，而不管其中的药物量。 泵包括设置在均压压力室内的波纹管组件，并且将以与环境温度，环境压力或储存器中剩余的药物量无关的预定流速将药物通过波纹管组件输送。 FAMIS设计还提供了防止意外过量的细菌传播到身体中并防止储存器内的气泡阻止药物流过形成FAMIS泵的一部分的出口限流器的保护装置。
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88.发明授权Guiding catheter with sealing cap system for reducing blood loss when inserting guiding catheters 失效引导导管，带有密封帽系统，用于在引导导管插入时减少失血
公开(公告)号：US5413561A
公开(公告)日：1995-05-09
申请号：US60656
申请日：1993-05-13
CPC分类号： A61M39/20 , A61M39/0606 , A61M2039/062 , A61M2039/0633 , A61M25/0097 , A61M25/0662
摘要： The invention is a system for reducing blood loss when placing a guiding catheter into an artery of a human subject. The system consists of a guiding catheter, a sealing means to be placed on the guiding catheter's proximal end and a guide wire that can be placed through both the guiding catheter and the sealing means to assist in placing the guiding catheter into a specific artery. The sealing means is typically a cap consisting of a male Luer lock fitting that includes a hemostasis valve that is designed to seal around the guide wire. The cap can be a separate component or it can be joined to the guiding catheter's proximal end by means of a flexible hinge. After the guiding catheter has been placed at a desired location in the arterial system, the cap and guide wire can be removed and a "Y" adaptor would then be placed onto the guiding catheter's proximal end. If desired the flexible hinge could also be removed from the guiding catheter.
摘要翻译： 本发明是一种用于在将引导导管置于人受试者的动脉中时减少失血的系统。 该系统由引导导管，被放置在引导导管的近端上的密封装置和可以通过引导导管和密封装置两者放置以辅助将引导导管放置在特定动脉中的引导线组成。 密封装置通常是由公Luer锁定配件组成的帽，其包括被设计成密封导丝周围的止血阀。 盖可以是单独的部件，或者可以通过柔性铰链连接到引导导管的近端。 在引导导管已经放置在动脉系统中的期望位置之后，可以去除帽和导丝，并且然后将“Y”适配器放置在引导导管的近端上。 如果需要，柔性铰链也可以从引导导管移除。
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公开(公告)号：US5324262A
公开(公告)日：1994-06-28
申请号：US15530
申请日：1993-02-09
CPC分类号： A61M25/0662
摘要： An introducer sheath (10) is provided for percutaneous insertion of catheters into a blood vessel. The introduction of the sheath (10) through a wall of blood vessel causes an opening to be formed through which blood may pass from the blood vessel. The sheath(10) includes an inflatable collar (20) which may be expanded under pressurized inflation of fluid inserted within the inflatable collar (20) to expand into contiguous contact with a periphery of the opening formed by the sheath (10) to prevent blood leakage through the blood vessel wall opening.
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公开(公告)号：US4886061A
公开(公告)日：1989-12-12
申请号：US153912
申请日：1988-02-09
CPC分类号： A61B17/32075 , A61B17/22012 , A61B18/00 , A61B18/245
摘要： Disclosed is an Expandable Pullback Atherectomy Catheter (EPAC) comprising a distal tip portion capable of assuming two diameters. The distal tip portion includes an expandable cutting means and an expandable tissue collecting means. The catheter is guided in an artery to the stenosis and the distal tip is urged past the stenosis while being maintained in a compressed state by a sheathing catheter. The sheathing catheter is withdrawn allowing the cutting means and collecting means to expand. The stenotic tissue is removed by pulling the distal tip back in a retrograde direction while the cut tissue is captured in the collecting means. Additional structural details are provided to prevent injury to the inner wall of an artery and to avoid total obstruction of the artery during the antherectomy procedure.
摘要翻译： 本发明公开了一种可扩张式回退粥样硬化斑块切除术导管（EPAC），其包括能够呈现两个直径的远侧末端部分。 远侧末端部分包括可扩张切割装置和可扩张组织收集装置。 导管在动脉中被引导至狭窄，并且通过护套导管将远侧末端推压通过狭窄，同时保持在压缩状态。 取出护套导管，允许切割装置和收集装置膨胀。 通过沿着逆行方向拉动远侧末端，同时将切割的组织捕获在收集装置中来移除狭窄组织。 提供了额外的结构细节，以防止对动脉内壁的损伤，并避免在切除手术期间完全阻塞动脉。
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