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133 条记录 (耗时 0.031 秒)

    Method and device for treating myocardial ischemia
    81.
    发明授权
    Method and device for treating myocardial ischemia 有权
    治疗心肌缺血的方法和装置

    公开(公告)号：US08412324B2

    公开(公告)日：2013-04-02

    申请号：US13103477

    申请日：2011-05-09

    申请人： Rodney W. Salo ,  Allan C. Shuros ,  Tamara Colette Baynham

    发明人： Rodney W. Salo ,  Allan C. Shuros ,  Tamara Colette Baynham

    IPC分类号： A61N1/362

    CPC分类号： A61N1/3627 ,  A61N1/3684

    摘要： A method and device for treating myocardial ischemia are described in which the stress experienced by a myocardial region identified as vulnerable to becoming ischemic is varied with pre-excitation pacing. In an unloading mode, pacing is applied in proximity to the vulnerable region to reduce stress and the metabolic demand of the region. In a loading mode, pacing is applied to a region remote from the vulnerable region in order to produce a conditioning effect.

    摘要翻译： 描述了一种用于治疗心肌缺血的方法和装置，其中被认为易于变得缺血的心肌区域所经受的压力随着预激发起搏而变化。 在卸载模式下，起搏应用于脆弱区域附近，以减少该地区的压力和代谢需求。 在加载模式中，起搏应用于远离脆弱区域的区域，以产生调节效果。

    REDUCTION OF AV DELAY FOR TREATMENT OF CARDIAC DISEASE
    83.
    发明申请
    REDUCTION OF AV DELAY FOR TREATMENT OF CARDIAC DISEASE 有权
    减少AV延迟治疗心脏病

    公开(公告)号：US20110319955A1

    公开(公告)日：2011-12-29

    申请号：US13229948

    申请日：2011-09-12

    申请人： Joseph M. Pastore ,  Rodney W. Salo ,  Julio C. Spinelli ,  Allan C. Shuros ,  Andres Belalcazar

    发明人： Joseph M. Pastore ,  Rodney W. Salo ,  Julio C. Spinelli ,  Allan C. Shuros ,  Andres Belalcazar

    IPC分类号： A61N1/365

    CPC分类号： A61N1/3627 ,  A61N1/36521 ,  A61N1/36535 ,  A61N1/36542 ,  A61N1/36564 ,  A61N1/3688

    摘要： An implantable pacing device for delivering ventricular pacing may be configured to intermittently reduce the AVD interval for beneficial effect in patients with compromised ventricular function (e.g., HF patients and post-MI patients). The AVD interval may be reduced in an AVD reduction mode, by shortening the AVD in an atrial triggered ventricular pacing mode or by switching to a non-atrial triggered ventricular pacing mode (e.g., VVI) and delivering paces at a rate above the intrinsic rate. The physiological effects of AVD reduction may be either positive or negative on cardiac output, depending upon the individual patient.

    摘要翻译： 用于输送心室起搏的可植入起搏装置可以被配置为间歇地减小AVD间隔，以在患有心室功能受损的患者（例如，HF患者和MI后患者）中产生有益效果。 通过在心房触发的心室起搏模式中缩短AVD或者通过切换到非心房触发的心室起搏模式（例如，VVI）并以高于内在速率的速率递送步进，AVD间期可以减小AVD减小模式 。 取决于个体患者，AVD减少的生理作用可能是心输出量的正或负。

    Cardiac rhythm management system with optimization of cardiac performance using heart rate
    84.
    发明授权
    Cardiac rhythm management system with optimization of cardiac performance using heart rate 有权
    心脏节律管理系统使用心率优化心脏性能

    公开(公告)号：US08065000B2

    公开(公告)日：2011-11-22

    申请号：US12697545

    申请日：2010-02-01

    申请人： Rodney W. Salo ,  Kenneth L. Baker ,  Lawrence S. Baumann

    发明人： Rodney W. Salo ,  Kenneth L. Baker ,  Lawrence S. Baumann

    IPC分类号： A61N1/362

    CPC分类号： A61N1/3702 ,  A61N1/3627 ,  A61N1/3682 ,  A61N1/3684 ,  A61N1/3688

    摘要： A method of optimizing inter-site delay is disclosed for a cardiac rhythm management device that includes a dual chamber pacemaker, especially designed for treating congestive heart failure by pacing a plurality of sites. A microcontroller is operative to adjust the pacing mode and inter-site delay of the pacemaker so as to achieve optimum hemodynamic performance. Atrial cycle lengths measured during transient (immediate) time intervals following a change in the mode inter-site delay are signal processed and a determination can then be made as to which particular configuration yields the optimum performance. Performance is optimized when the patient is at rest and when the patient exercises so that a rate-adapted dynamic value of the optimum performance can be applied.

    摘要翻译： 公开了一种用于心脏节律管理装置的优化站间延迟的方法，其包括双室起搏器，其特别设计用于通过起搏多个部位来治疗充血性心力衰竭。 微控制器可操作以调节起搏器的起搏模式和站间延迟，以达到最佳的血液动力学性能。 信号处理后的瞬时（即时）时间间隔内测量的心房周期长度被信号处理，然后可以确定哪个特定配置产生最佳性能。 当患者处于静止状态并且患者锻炼时优化性能，以便可以应用最佳性能的速率适应动态值。

    BAROREFLEX STIMULATOR WITH INTEGRATED PRESSURE SENSOR
    86.
    发明申请
    BAROREFLEX STIMULATOR WITH INTEGRATED PRESSURE SENSOR 审中-公开
    具有集成压力传感器的BAROREFLEX刺激器

    公开(公告)号：US20110106216A1

    公开(公告)日：2011-05-05

    申请号：US12987689

    申请日：2011-01-10

    申请人： Imad Libbus ,  Rodney W. Salo

    发明人： Imad Libbus ,  Rodney W. Salo

    IPC分类号： A61N1/36

    CPC分类号： A61N1/36117 ,  A61N1/36057 ,  A61N1/36564

    摘要： An aspect relates to an implantable medical device. An embodiment of the device comprises a pulse generator, sensor circuitry, a lead, and a controller. The pulse generator generates baroreflex stimulation pulses. The lead is adapted to be electrically connected to the pulse generator and to the sensor circuitry. The lead includes an electrode to distribute the baroreflex stimulation pulses to a baroreflex site and a pressure sensor to provide a signal indicative of blood pressure to the sensor circuitry. The controller is connected to the pulse generator and the sensor circuitry. The controller adapted to adjust the baroreflex stimulation pulses based on the blood pressure. Other aspects are provided herein.

    摘要翻译： 一个方面涉及可植入医疗装置。 该装置的实施例包括脉冲发生器，传感器电路，引线和控制器。 脉冲发生器产生压力反射刺激脉冲。 引线适于电连接到脉冲发生器和传感器电路。 引线包括用于将压力反射刺激脉冲分布到压力反射部位的电极和压力传感器，以向传感器电路提供指示血压的信号。 控制器连接到脉冲发生器和传感器电路。 控制器适于基于血压调节压力反射刺激脉冲。 本文提供了其他方面。

    CARDIAC RHYTHM MANAGEMENT SYSTEM WITH OPTIMIZATION OF CARDIAC PERFORMANCE USING HEART RATE
    87.
    发明申请
    CARDIAC RHYTHM MANAGEMENT SYSTEM WITH OPTIMIZATION OF CARDIAC PERFORMANCE USING HEART RATE 有权
    CARDIAC RHYTHM管理系统优化使用心率的心脏功能

    公开(公告)号：US20100137933A1

    公开(公告)日：2010-06-03

    申请号：US12697545

    申请日：2010-02-01

    申请人： Rodney W. Salo ,  Kenneth L. Baker ,  Lawrence S. Baumann

    发明人： Rodney W. Salo ,  Kenneth L. Baker ,  Lawrence S. Baumann

    IPC分类号： A61N1/365

    CPC分类号： A61N1/3702 ,  A61N1/3627 ,  A61N1/3682 ,  A61N1/3684 ,  A61N1/3688

    摘要： A method of optimizing inter-site delay is disclosed for a cardiac rhythm management device that includes a dual chamber pacemaker, especially designed for treating congestive heart failure by pacing a plurality of sites. A microcontroller is operative to adjust the pacing mode and inter-site delay of the pacemaker so as to achieve optimum hemodynamic performance. Atrial cycle lengths measured during transient (immediate) time intervals following a change in the mode inter-site delay are signal processed and a determination can then be made as to which particular configuration yields the optimum performance. Performance is optimized when the patient is at rest and when the patient exercises so that a rate-adapted dynamic value of the optimum performance can be applied.

    摘要翻译： 公开了一种用于心脏节律管理装置的优化站间延迟的方法，其包括双室起搏器，其特别设计用于通过起搏多个部位来治疗充血性心力衰竭。 微控制器可操作以调节起搏器的起搏模式和站间延迟，以达到最佳的血液动力学性能。 信号处理后的瞬时（即时）时间间隔内测量的心房周期长度被信号处理，然后可以确定哪个特定配置产生最佳性能。 当患者处于静止状态并且患者锻炼时优化性能，以便可以应用最佳性能的速率适应动态值。