利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

433 条记录 (耗时 0.041 秒)

    Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power
    82.
    发明授权
    Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power 失效
    用于与电力源一起递送治疗剂的内部医疗装置

    公开(公告)号：US07850645B2

    公开(公告)日：2010-12-14

    申请号：US11055930

    申请日：2005-02-11

    申请人： Liliana Atanasoska ,  Thomas J. Holman ,  Jan Weber ,  Robert Warner ,  Scott Schewe

    发明人： Liliana Atanasoska ,  Thomas J. Holman ,  Jan Weber ,  Robert Warner ,  Scott Schewe

    IPC分类号： A61M29/00

    CPC分类号： A61N1/325 ,  A61N1/05 ,  A61N1/306 ,  A61N1/327

    摘要： The invention generally relates to internal (e.g., implantable, insertable, etc.) drug delivery devices which contain the following: (a) one or more sources of one or more therapeutic agents; (b) one or more first electrodes, (c) one or more second electrodes and (d) one or more power sources for applying voltages across the first and second electrodes. The power sources may be adapted, for example, to promote electrically assisted therapeutic agent delivery within a subject, including electroporation and/or iontophoresis. In one aspect of the invention, the first and second electrodes are adapted to have tissue of a subject positioned between them upon deployment of the medical device within the subject, such that an electric field may be generated, which is directed into the tissue. Furthermore, the therapeutic agent sources are adapted to introduce the therapeutic agents into the electric field. In another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of ion-conductive polymers and one or more types of charged therapeutic agents. In yet another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of electrically conductive polymers and one or more types of charged therapeutic agents.

    摘要翻译： 本发明一般涉及含有以下物质的内部（例如，可植入，可插入等）药物递送装置：（a）一种或多种一种或多种治疗剂来源; （b）一个或多个第一电极，（c）一个或多个第二电极和（d）用于在第一和第二电极上施加电压的一个或多个电源。 电源可以适应于例如促进受试者内的电辅助治疗剂递送，包括电穿孔和/或离子电渗疗法。 在本发明的一个方面中，第一和第二电极适于在医疗装置在受试者内展开时使被检体的组织位于它们之间，使得可以产生被引导到组织中的电场。 此外，治疗剂源适于将治疗剂引入电场。 另一方面，治疗剂来源是含有一种或多种类型的离子导电聚合物和一种或多种类型的带电治疗剂的聚合物区域。 在另一方面，治疗剂来源是含有一种或多种类型的导电聚合物和一种或多种类型的带电治疗剂的聚合物区域。

    Resonator with adjustable capacitor for medical device
    84.
    发明授权
    Resonator with adjustable capacitor for medical device 失效
    谐振器用于医疗设备的可调电容器

    公开(公告)号：US07838806B2

    公开(公告)日：2010-11-23

    申请号：US11982548

    申请日：2007-11-02

    申请人： Jan Weber

    发明人： Jan Weber

    IPC分类号： H05B6/36

    CPC分类号： G01R33/286 ,  A61B5/055 ,  A61F2/82 ,  G01R33/3628 ,  Y10T29/49117

    摘要： An apparatus, system and method of a resonator device with an adjustable capacitor for allowing the resonance frequency (F) of the resonator device to continue to be matched to the Larmor frequency of the MRI system. The resonator device includes an inductor coil, a conductive member, a sleeve having first and second sockets that receive at least portions of the inductor coil and the conductive member as electrodes to provide a capacitor structure. Dielectric material can be positioned between at least the first and second sockets, where changes in the cross sectional area defined by the induction coil cause changes in the capacitance value (C) as one or more of the electrodes move within the socket. Changes in the inductance and the capacitance values allow for the resonance frequency (F) of the resonator device to continue to be matched to the Larmor frequency of the MRI system.

    摘要翻译： 具有可调电容器的谐振器装置的装置，系统和方法，用于允许谐振器装置的谐振频率（F）继续与MRI系统的拉莫尔频率匹配。 谐振器装置包括电感线圈，导电构件，具有第一和第二插座的套筒，该套管至少容纳电感器线圈和导电构件的至少一部分作为电极以提供电容器结构。 介电材料可以位于至少第一和第二插座之间，其中由感应线圈限定的横截面积的变化引起电容值（C）的变化，因为一个或多个电极在插座内移动。 电感和电容值的变化允许谐振器装置的谐振频率（F）继续与MRI系统的拉莫尔频率匹配。

    Medical Devices
    85.
    发明申请
    Medical Devices 有权
    医疗设备

    公开(公告)号：US20100286678A1

    公开(公告)日：2010-11-11

    申请号：US12838980

    申请日：2010-07-19

    申请人： Jan Weber ,  John M. Hokanson ,  John H. Chen

    发明人： Jan Weber ,  John M. Hokanson ,  John H. Chen

    IPC分类号： A61B18/02 ,  A61B18/04 ,  A61M25/10

    CPC分类号： A61M25/104 ,  A61F7/123 ,  A61L29/126 ,  A61M25/10 ,  B82Y5/00 ,  B82Y30/00

    摘要： Medical systems and methods including balloons having nanotubes are disclosed. In some embodiments, a medical system includes an elongated shaft, and an expandable balloon carried by the shaft and including nanotubes. The medical system is capable of cooling the balloon to less than about 37° C. In some embodiments, a method includes providing a medical device having an elongated shaft, and an expandable balloon carried by the elongated shaft and including nanotubes; and cooling the balloon to less than about 37° C.

    摘要翻译： 公开了包括具有纳米管的气囊的医疗系统和方法。 在一些实施例中，医疗系统包括细长轴和由轴承载并包括纳米管的可膨胀气囊。 医疗系统能够将球囊冷却到小于约37℃。在一些实施例中，一种方法包括提供具有细长轴的医疗装置和由细长轴承载并包括纳米管的可膨胀气囊; 并将气球冷却至小于约37℃。

    Devices and methods for magnetically manipulating intravascular devices
    87.
    发明授权
    Devices and methods for magnetically manipulating intravascular devices 失效
    用于磁操作血管内装置的装置和方法

    公开(公告)号：US07799050B2

    公开(公告)日：2010-09-21

    申请号：US10838988

    申请日：2004-05-05

    申请人： Joseph Hensley ,  Thomas E. Broome ,  Jan Weber

    发明人： Joseph Hensley ,  Thomas E. Broome ,  Jan Weber

    IPC分类号： A61M29/00

    CPC分类号： A61F2/01 ,  A61F2002/011 ,  A61F2002/016 ,  A61F2210/009 ,  A61F2230/005 ,  A61F2230/0067

    摘要： Devices and methods for magnetically centering and retrieving intravascular devices within a body lumen are disclosed. An intravascular filter in accordance with an illustrative embodiment may comprise an expandable filter structure having at least one magnetic element formed therein. The intravascular filter can be retrieved using a magnetic retrieval device that includes a magnetic retrieval mechanism for centering and retrieving the intravascular filter.

    摘要翻译： 公开了用于磁体定心和取回体腔内的血管内装置的装置和方法。 根据说明性实施例的血管内过滤器可以包括其中形成有至少一个磁性元件的可膨胀过滤器结构。 血管内过滤器可以使用包括用于对中和取回血管内过滤器的磁回收机构的磁回收装置来取回。

    Tunable MRI enhancing device
    89.
    发明授权
    Tunable MRI enhancing device 有权
    可调MRI增强装置

    公开(公告)号：US07725160B2

    公开(公告)日：2010-05-25

    申请号：US10216988

    申请日：2002-08-12

    申请人： Jan Weber

    发明人： Jan Weber

    IPC分类号： A61B5/05

    CPC分类号： G01R33/285 ,  G01R33/3628

    摘要： The present invention is directed to an MRI enhancing device deployable in a body. In one embodiment, the MRI enhancing device is formed of a wire loop and a capacitor that is at least partially formed by the wire used in forming the wire loop.

    摘要翻译： 本发明涉及一种可在体内展开的MRI增强装置。 在一个实施例中，MRI增强装置由线环和至少部分地由形成线环的电线形成的电容器形成。

    ENDOPROSTHESES WITH POROUS REGIONS AND NON-POLYMERIC COATING
    90.
    发明申请
    ENDOPROSTHESES WITH POROUS REGIONS AND NON-POLYMERIC COATING 审中-公开
    具有多孔区域和非聚合涂层的内部结构

    公开(公告)号：US20100057188A1

    公开(公告)日：2010-03-04

    申请号：US12200530

    申请日：2008-08-28

    申请人： Jan Weber

    发明人： Jan Weber

    IPC分类号： A61F2/06

    CPC分类号： A61L31/022 ,  A61L31/028 ,  A61L31/146 ,  A61L31/16 ,  A61L2300/608

    摘要： Endoprostheses include an endoprosthesis wall that includes a surface layer that includes a metallic material and that defines a plurality of pores. A therapeutic agent fills one or more pores of the surface layer and a non-polymeric coating, covers the therapeutic agent in the one or more pores. The endoprostheses can, for example, deliver a therapeutic agent, such as a drug, in a controlled manner over an extended period of time.

    摘要翻译： 内假体包括内置假体壁，其包括包含金属材料并限定多个孔的表面层。 治疗剂填充表面层的一个或多个孔和非聚合物涂层，覆盖一个或多个孔中的治疗剂。 内用假体可以例如以长期的控制方式递送诸如药物的治疗剂。