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公开(公告)号：US06447501B1
公开(公告)日：2002-09-10
申请号：US09454255
申请日：1999-12-02
申请人： Ronald J. Solar , Glen L. Lieber
发明人： Ronald J. Solar , Glen L. Lieber
IPC分类号： A61M2501
CPC分类号： A61M25/104 , A61M25/0067 , A61M25/007 , A61M25/01 , A61M25/0105 , A61M25/0108 , A61M25/0662 , A61M29/02 , A61M2025/0008 , A61M2025/0177 , A61M2025/0183 , A61M2025/1056 , A61M2025/1061 , A61M2025/1093 , A61M2029/025
摘要： A stent delivery system is comprised of an elongated flexible advancement member which terminates in a tubular tracking member slidable over a guidewire. An inflatable balloon has proximal and distal ends, the proximal end communicating with an inflation channel, and the distal end attaching to the tracking member. The balloon portion is coextensive with but not attached to the advancement member.
摘要翻译： 支架输送系统包括细长的柔性进给构件，其终止于可在导丝上滑动的管状跟踪构件。 可充气气囊具有近端和远端，近端与充气通道连通，远端连接到跟踪构件。 球囊部分共同延伸但未附着到推进构件。
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公开(公告)号：US20020082548A1
公开(公告)日：2002-06-27
申请号：US09745828
申请日：2000-12-21
IPC分类号： A61M029/00
CPC分类号： A61M25/0026 , A61M25/0021 , A61M25/005 , A61M25/0052 , A61M25/104 , A61M2025/0039 , A61M2025/004 , A61M2025/0063 , A61M2025/1061 , A61M2029/025
摘要： The invention is generally directed to an intraluminal catheter systems including an elongated shaft having proximal and distal shaft sections, and an inflatable member disposed on the distal shaft section and having an interior chamber. A guidewire receiving lumen extends along at least a portion of the proximal shaft section and at least a portion of the distal shaft section and extends distally to the shaft distal end. An inflation lumen extends along at least a portion of the proximal shaft section and at least a portion of the distal shaft section to a point proximal to a shaft distal end and is in fluid communication with the inflatable member interior chamber. The proximal shaft section has multiple non-concentric lumens with at least one lumen forming at least a portion of the guidewire receiving lumen and at least one lumen forming at least a portion of the inflation lumen.
摘要翻译： 本发明总体上涉及一种管腔内导管系统，其包括具有近端和远端轴段的细长轴，以及设置在远端轴部分上并具有内部腔室的可充气构件。 导丝接收腔沿着近轴部分的至少一部分和远侧轴部分的至少一部分延伸并且向远侧延伸到轴远端。 充气腔沿着近端轴部分的至少一部分和远侧轴部分的至少一部分延伸到靠近轴远端的点并且与可充气构件内部腔室流体连通。 近端轴段具有多个非同心腔，其具有至少一个内腔，其形成导丝接收腔的至少一部分，以及形成至少一部分充气腔的至少一个腔。
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公开(公告)号：US06273879B1
公开(公告)日：2001-08-14
申请号：US09132119
申请日：1998-08-11
IPC分类号： A21M2500
CPC分类号： A61M25/104 , A61M25/0029 , A61M25/0032 , A61M25/0054 , A61M25/0662 , A61M2025/0034 , A61M2025/0079 , A61M2025/0098 , A61M2025/0183 , A61M2025/09191 , A61M2025/1056 , A61M2025/1061 , A61M2025/1079
摘要： An over-the-wire balloon dilatation catheter has a stainless steel hypotube catheter shaft, an intermediate sleeve section bonded to the shaft and a distal balloon section connected to the sleeve section. The sleeve section is formed from relatively flexible polymer materials and includes an inner core tube which defines a guide wire lumen extending only through a distal portion of the catheter (including its sleeve and balloon sections) to facilitate fast balloon catheter exchanges. A distal end of the hypotube shaft is crimped laterally and the core tube is nested and bonded within the crimp to provide a proximal outlet for the guide wire lumen. The hypotube shaft provides an inflation lumen for the balloon, with the inflation lumen being continued as an annular inflation lumen through the sleeve section where an outer sleeve is bonded about the core tube and extends from the distal end of the hypotube shaft to the balloon section. A kink-resistant coil structure extends distally from the distal end of the hypotube shaft to provide a gradual change in stiffness along the length of the catheter from the relatively stiff hypotube shaft to the relatively flexible distal portion of the catheter.
摘要翻译： 超线球囊扩张导管具有不锈钢海波管导管轴，粘结到轴的中间套筒部分和连接到套筒部分的远端球囊部分。 套筒部分由相对柔性的聚合物材料形成并且包括内芯管，其限定仅通过导管的远端部分（包括其套管和气囊部分）延伸的导丝管腔，以便于快速气囊导管交换。 海波管轴的远端横向卷曲，并且芯管嵌套并粘合在卷曲内以提供用于导丝管腔的近端出口。 海波管轴为球囊提供充气腔，其中膨胀腔作为通过套管部分的环形膨胀腔继续，其中外套筒围绕芯管结合并且从海波管的远端延伸到球囊部分 。 抗扭线圈结构从海波管的远端向远端延伸，以沿着导管的长度从相对刚性的海波管轴到导管的相对柔性的远侧部分逐渐改变刚度。
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84.发明授权
公开(公告)号：US6059713A
公开(公告)日：2000-05-09
申请号：US35705
申请日：1998-03-05
CPC分类号： A61N5/1002 , A61M2025/0063 , A61M2025/0656 , A61M2025/1061 , A61M25/0138 , A61M25/1002 , A61M25/104 , A61N2005/1003 , A61N2005/1004
摘要： A radiation source for inhibiting restenosis including a radiation delivery tube having a radioactive distal region, the tube being adapted to slide over a core wire within a radiation delivery catheter. The core wire is preferably in a slidable relation with the radiation delivery catheter. By withdrawing the core wire to a proximal position, the flexibility of a distal region of the radiation delivery catheter may be increased, thereby allowing the radiation delivery catheter to navigate more tortuous paths and reach more distal sites. Before the radiation delivery tube is advanced into the catheter distal region, the core wire is preferably slid distally to a distal position. With the core wire in the distal position, the core wire may provide a structure that can be used to rapidly advance the radiation source to the lesion site. The core wire may also help constrain lateral movement of the radiation delivery tube and help center the radiation delivery tube within the vessel to provide a more even radiation exposure to the vessel walls.
摘要翻译： 一种用于抑制再狭窄的辐射源，包括具有放射性远侧区域的辐射递送管，所述管适于在辐射递送导管内的芯线上滑动。 芯线优选地与辐射递送导管可滑动关系。 通过将芯线抽出到近端位置，可以增加放射线输送导管的远端区域的柔性，从而允许放射线输送导管更多的曲折路径导航并到达更远侧的位置。 在辐射输送管进入导管远端区域之前，芯线优选地向远侧滑动到远端位置。 在芯线处于远端位置时，芯线可以提供可用于将辐射源快速推进到病变部位的结构。 芯线还可以有助于限制辐射输送管的横向运动，并帮助辐射输送管在容器内居中以提供更均匀的辐射暴露于血管壁。
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公开(公告)号：US5921958A
公开(公告)日：1999-07-13
申请号：US708553
申请日：1996-09-06
CPC分类号： A61M25/0068 , A61M25/0662 , A61M25/104 , A61M2025/0037 , A61M2025/0047 , A61M2025/0063 , A61M2025/0079 , A61M2025/0183 , A61M2025/1061 , A61M2025/1093 , A61M25/003 , A61M25/0054 , A61M25/008
摘要： A catheter for use in angioplasty includes a shaft formed from an elongated metallic tube and has an inflatable balloon at its distal end. A plastic tube connects a distal end of the metallic tube to a proximal end of the balloon. The metallic and plastic tubes thus define a lumen for providing inflation pressure to the balloon. A metallic core member is attached to the metallic tube and extends distally therefrom through the plastic tube and balloon. The distal end of the balloon is sealably secured to the core member. A tip body is connected to the core member distally of the balloon, with a short guide wire lumen being defined on the tip body. The guide wire lumen is adapted to slidably receive a guide wire which then extends along the catheter exteriorly of the balloon.
摘要翻译： 用于血管成形术的导管包括由细长金属管形成的轴，并且在其远端具有可充气气囊。 塑料管将金属管的远端连接到球囊的近端。 因此，金属和塑料管限定用于向球囊提供充气压力的内腔。 一个金属芯件连接在金属管上，并通过塑料管和气球向远端延伸。 气囊的远端可密封地固定在芯部件上。 尖端体与气囊的远侧的核心部件连接，在前端体上限定有短导丝管腔。 导丝管腔适于可滑动地容纳导丝，然后导管沿气囊外部的导管延伸。
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86.发明授权Double tube, balloon catheter produced by using double tube, and process for producing balloon catheter 失效使用双管制造的双管，气囊导管，以及用于制造球囊导管的方法
公开(公告)号：US5833672A
公开(公告)日：1998-11-10
申请号：US849316
申请日：1997-06-10
CPC分类号： A61M25/1036 , A61M25/1027 , A61M2025/0034 , A61M2025/1061 , A61M25/0029 , A61M25/0053 , A61M25/10
摘要： A double tube from which a balloon catheter having a high rigidity and a low fluid resistance can be easily produced by means of an extruder or the like, an apparatus for producing the double tube, a balloon catheter produced by using the double tube, and a process for producing the balloon catheter are provided. The double tube comprises an outer tube having a lumen extending from the distal end to the proximal end, and an inner tube which is provided within the outer tube and has a lumen extending from the distal end to the proximal end, wherein a longitudinal member in the strip form is provided as a connecting member which continuously connects the inner surface of the outer tube to the outer surface of the inner tube in the axial direction. A balloon catheter can be easily produced by using this double tube. An apparatus for producing a double tube is also provided which comprises a first extruding means for extruding a resin for forming an outer tube portion, a second extruding means for extruding a resin for forming an inner tube portion, and a die for forming into tubes respectively from the resins extruded from the first extruding means and the second extruding means.
摘要翻译： PCT No.PCT / JP95 / 02534 Sec。 371日期：1997年6月10日 102（e）日期1997年6月10日PCT 1995年11月11日PCT PCT。 公开号WO96 / 18430 日期：1996年6月20日利用挤出机等容易地制造具有高刚性和低流体阻力的球囊导管的双管，用于生产双管的装置，使用 双管，以及用于制造球囊导管的方法。 双管包括具有从远端延伸到近端的内腔的外管，以及设置在外管内并具有从远端延伸到近端的内腔的内管，其中纵管 提供带状形式作为连接构件，其将外管的内表面沿着轴向连续地连接到内管的外表面。 可以通过使用该双管容易地制造球囊导管。 还提供了一种用于制造双管的装置，其包括用于挤出用于形成外管部的树脂的第一挤出装置，用于挤出用于形成内管部的树脂的第二挤出装置和分别形成管的模具 从第一挤出装置和第二挤出装置挤出的树脂。
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公开(公告)号：US5788631A
公开(公告)日：1998-08-04
申请号：US608714
申请日：1996-02-29
CPC分类号： A61B5/14542 , A61B5/14539 , A61M25/10 , A61M25/1011 , A61M2025/0177 , A61M2025/1061
摘要： Ischemia in a hollow internal organ can be detected in its incipient stages by obtaining a CO.sub.2 sample from within the organ of interest, measuring the partial pressure of CO.sub.2 sample, measuring the bicarbonate concentration of an arterial blood sample, and on the basis of these two measurements calculating the pH of the wall of the organ. The value of the pH is an indicator of the onset of ischemia in the organ. The CO.sub.2 sample is obtained by a novel catheter, multiple embodiments of which are disclosed. Also disclosed is a method for determining the vitality or adequacy of oxygenation of the whole body, or a solid internal organ, by the measurement of the pH of venous blood.
摘要翻译： 通过从感兴趣的器官内获得二氧化碳样本，测量二氧化碳样本的分压，测量动脉血样品的碳酸氢盐浓度，并在这两个基础上，可以在初期阶段检测中空内脏器官缺血 测量器官壁的pH值。 pH值是器官缺血发作的指标。 通过新型导管获得二氧化碳样品，其多个实施方案被公开。 还公开了通过测量静脉血的pH来确定全身或固体内脏器官的氧合活力或充足性的方法。
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88.发明授权
公开(公告)号：US5658251A
公开(公告)日：1997-08-19
申请号：US439959
申请日：1995-05-12
CPC分类号： A61M25/104 , A61M25/0662 , A61M2025/0034 , A61M2025/0047 , A61M2025/0063 , A61M2025/0079 , A61M2025/0098 , A61M2025/0183 , A61M2025/09191 , A61M2025/1056 , A61M2025/1061 , A61M2025/1077 , A61M2025/1079 , A61M2025/1093 , A61M25/003 , A61M25/0032 , A61M25/0054
摘要： An over-the-wire balloon dilatation catheter of the short guide wire lumen type has a stainless steel hypotube catheter shaft section, a distal plastic shaft section attached to the hypotube and a balloon connected to the distal plastic shaft section. A relatively short guide wire lumen extends throughout the length of the balloon. The distal shaft section includes a reinforcing and kink-resistant transition member extending throughout the length of the distal shaft section. The transition member allows the proximal guide wire lumen aperture to be placed distally from the distal end of the hypotube. This configuration permits the length of the guide wire lumen to be minimized.
摘要翻译： 短导丝管腔型的超线球囊扩张导管具有不锈钢海波管导管轴部分，附接到海波管的远端塑料轴部分和连接到远端塑料轴部分的气囊。 相对较短的导丝腔在气囊的整个长度上延伸。 远侧轴部分包括延伸穿过远侧轴部分的整个长度的加强和扭结过渡部件。 过渡构件允许近端导丝管腔孔从海波管的远端向远侧放置。 这种构造允许导丝管腔的长度最小化。
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公开(公告)号：US5456251A
公开(公告)日：1995-10-10
申请号：US322081
申请日：1994-10-12
CPC分类号： A61B5/14542 , A61B5/14539 , A61B5/1459 , A61B5/1473 , A61B5/6853 , A61M25/10 , A61M2025/1061
摘要： A tonometric device for use in hollow viscus tonometry and remote sensing of patient fluid parameters is disclosed in combination with a secondary apparatus, such as a urinary catheter, a nasogastric sump apparatus, or a feeding tube, for example. The device is capable of monitoring certain critical fluid properties of interest, such as oxygen gases and carbon dioxide gases in the wall tissue itself of the patient's organ, rather than monitoring such properties in a lumen of the organ. A walled sampling chamber, which is preferably an inflated balloon member, is provided on an elongated tube, with provisions for positioning the sampling chamber in direct contact with a wall portion of the patient's internal organ.
摘要翻译： 本发明公开了一种用于中空粘度眼压测量和远程感测患者流体参数的测量装置，其与例如尿导管，鼻胃槽装置或进料管的辅助装置组合。 该装置能够监测感兴趣的某些临界流体性质，例如患者器官的壁组织本身中的氧气和二氧化碳气体，而不是监测器官的内腔中的这些特性。 优选为膨胀的气囊构件的壁式采样室设置在细长管上，其具有将采样室定位成与患者内脏的壁部直接接触的装置。
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公开(公告)号：US5370616A
公开(公告)日：1994-12-06
申请号：US204802
申请日：1994-03-02
CPC分类号： A61M25/104 , A61M25/0662 , A61M2025/0034 , A61M2025/0098 , A61M2025/0183 , A61M2025/09191 , A61M2025/1056 , A61M2025/1061 , A61M2025/1079 , A61M25/0029 , A61M25/0032 , A61M25/0054
摘要： An over-the-wire balloon dilatation catheter has a stainless steel hypotube catheter shaft, an intermediate sleeve section bonded to the shaft and a distal balloon section connected to the sleeve section. The sleeve section is formed from relatively flexible polymer materials and includes an inner core tube which defines a guide wire lumen extending only through a distal portion of the catheter (including its sleeve and balloon sections) to facilitate fast balloon catheter exchanges. A distal end of the hypotube shaft is crimped laterally and the core tube is nested and bonded within the crimp to provide a proximal outlet for the guide wire lumen. The hypotube shaft provides an inflation lumen for the balloon, with the inflation lumen being continued as an annular inflation lumen through the sleeve section where an outer sleeve is bonded about the core tube and extends from the distal end of the hypotube shaft to the balloon section. A kink-resistant coil structure extends distally from the distal end of the hypotube shaft to provide a gradual change in stiffness along the length of the catheter from the relatively stiff hypotube shaft to the relatively flexible distal portion of the catheter.
摘要翻译： 超线球囊扩张导管具有不锈钢海波管导管轴，粘结到轴的中间套筒部分和连接到套筒部分的远端球囊部分。 套筒部分由相对柔性的聚合物材料形成并且包括内芯管，其限定仅通过导管的远端部分（包括其套管和气囊部分）延伸的导丝管腔，以便于快速气囊导管交换。 海波管轴的远端横向卷曲，并且芯管嵌套并粘合在卷曲内以提供用于导丝管腔的近端出口。 海波管轴为气囊提供充气腔，其中膨胀腔作为环形充气腔通过套筒部分继续，其中外套筒围绕芯管结合并且从海波管的远端延伸到球囊部分 。 抗扭线圈结构从海波管的远端向远端延伸，以沿着导管的长度从相对刚性的海波管轴到导管的相对柔性的远侧部分逐渐改变刚度。
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