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公开(公告)号:US11406487B2
公开(公告)日:2022-08-09
申请号:US16284919
申请日:2019-02-25
摘要: A vascular graft suitable for implantation, and more particular to a vascular graft having an expandable outflow region for restoring patency of the graft after implantation into a body lumen.
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公开(公告)号:US11129971B2
公开(公告)日:2021-09-28
申请号:US16240305
申请日:2019-01-04
发明人: Wolfram Grziwa , Greg Peatfield
摘要: A chest drainage system, including a circulation assembly having an intake for taking fluid into the system and an exhaust for exhausting fluid out of the system. An intake flow device is configured to selectively control fluid flow through the intake and an exhaust flow device is configured to selectively controlling fluid flow through the exhaust. The circulation assembly has a first configuration and a second configuration such that transitioning between the first and second configurations during operation of the circulation assembly displaces at least a portion of fluid within the system with fluid from outside the system via the intake and the exhaust. A sensor is arranged in fluid communication with the fluid within the system and configured to detect a concentration of a reference fluid in the fluid in the system.
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公开(公告)号:US11097035B2
公开(公告)日:2021-08-24
申请号:US16213823
申请日:2018-12-07
IPC分类号: A61L31/08 , A61L29/08 , A61L29/14 , C09D191/00
摘要: Disclosed herein is the correlation of chemical properties of oils with the physical properties of a resulting cured oil composition. Also disclosed are biocompatible materials and coatings for medical devices prepared using enriched oils and methods for enhancing or modifying the physical and chemical characteristics of cured oils by enriching such oils with fatty acid alkyl esters. Methods of tailoring the properties of biocompatible materials and coatings to deliver one or more therapeutic agents are also provided.
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公开(公告)号:US20210121180A1
公开(公告)日:2021-04-29
申请号:US17078491
申请日:2020-10-23
发明人: Roger LABRECQUE , David HEIM
IPC分类号: A61B17/11
摘要: An endovascular fixation device includes a first portion and a second portion connected to the first portion to define a central lumen extending longitudinally through the portions. The first portion includes a first radially expandable ring and at least one first connector, connected to the first ring, configured to cause at least one first flarable crown of the first ring to flare radially outwardly relative to other portions of the first ring when the first ring is expanded from a retracted position to an expanded position. The second portion includes a second radially expandable ring and at least one second connector, connected to the second ring, configured to cause at least one second flarable crown of the second ring to flare radially outwardly relative to other portions of the second ring when the second ring is expanded from a retracted position to an expanded position.
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公开(公告)号:US10933175B2
公开(公告)日:2021-03-02
申请号:US15717237
申请日:2017-09-27
发明人: James Croteau , Theodore Karwoski , Joanne Krawczyk , Marc Larochelle , Patrick Lee , Nicholas Want
摘要: A chest drainage system including a collection device configured to receive fluid from the pleural cavity of a patient. A sensor is included to detect a pressure differential in the fluid. A display is configured to display a trend in occurrences of changes in pressure of the fluid over time in predetermined time increments based on a number of detections of pressure differentials that exceed a predetermined pressure differential during each of the predetermined time increments. The trend is correlative to the percentage of time that the patient is deemed to have an air leak in the pleural cavity in the predetermined time increments. The trend is derived from a ratio of the quantity of respiratory cycles of the patient for which the predetermined pressure differential is detected (QRCleak) in the predetermined time increments to the total quantity of respiratory cycles of the patient in respective predetermined time increments (QRCtotal).
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公开(公告)号:US20210045899A1
公开(公告)日:2021-02-18
申请号:US17088518
申请日:2020-11-03
发明人: John LANE , David HEIM , Christine SCHICK , Jennifer LETZELTER , Susan HAMELIN
摘要: A stent device includes generally cylindrical rings aligned along a longitudinal axis, and interconnected by interconnecting members. Each interconnecting member includes a first coupling end, a second coupling end, and an elongate portion therebetween. The first coupling end, the elongate portion, and the second coupling end combine in either a first orientation or a second orientation, which are substantially mirror images. For each interconnecting member, the first coupling end can intersect with a midpoint of a transition region of a substantially repeating curved segment on one of the rings, and the second coupling end can intersect with a midpoint of a curved segment of a different and immediately adjacent ring. The interconnecting members can be arranged in rows extending longitudinally along the device. Along each row, consecutive interconnected members alternate between the first orientation and the second orientation. A cover may be provided over the stent device.
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公开(公告)号:US20210038772A1
公开(公告)日:2021-02-11
申请号:US17070914
申请日:2020-10-14
IPC分类号: A61L31/08 , A61L31/16 , A61L31/14 , A61K31/202 , A61L15/46 , A61K31/765 , A61L27/50 , A61L29/14 , A01N37/36 , A61K33/38 , A61K31/232 , A61K31/35 , A61L15/34 , A61L27/54 , A01N61/00 , A61L29/16 , A61K31/155 , A61K45/06 , A61K31/09 , A61L31/00
摘要: A biomaterial including a plurality of fatty acid chains cross-linked together and elemental silver metal formed within the material. Method(s) for forming the material are also included. The silver-containing biomaterial can be utilized alone or in combination with a medical device for the release and local delivery of one or more anti-infective agents.
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公开(公告)号:US20210030928A1
公开(公告)日:2021-02-04
申请号:US17066466
申请日:2020-10-08
发明人: Keith M. FAUCHER , Hui TANG , Paul MARTAKOS , Theodore KARWOSKI , Alison SULLIVAN , Greg MELVILLE , Scott E. CORBEIL
IPC分类号: A61L31/08 , A61L31/16 , A61K31/4353 , A61L31/14
摘要: Fatty acid-based, pre-cure-derived biomaterials, methods of making the biomaterials, and methods of using them as drug delivery carriers are described. The fatty acid-derived biomaterials can be utilized alone or in combination with a medical device for the release and local delivery of one or more therapeutic agents. Methods of forming and tailoring the properties of said biomaterials and methods of using said biomaterials for treating injury in a mammal are also provided.
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公开(公告)号:US10888617B2
公开(公告)日:2021-01-12
申请号:US15819304
申请日:2017-11-21
IPC分类号: A61K47/12 , A61K47/22 , A61L27/14 , A61L27/34 , A61L27/54 , A61L31/04 , A61L31/10 , A61L31/16
摘要: The present invention is generally directed to materials, gels, coatings and films prepared using a biomaterial (e.g., a fatty acid-based material comprising a network of cross-linked fatty acids) and a fixating material, layer or film (e.g., a fixating material comprising Na-CMC). The materials, gels, coatings and films disclosed herein can be used to facilitate the delivery of one or more therapeutic agents to a targeted tissue and a desired rate of release.
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公开(公告)号:US20210002394A1
公开(公告)日:2021-01-07
申请号:US17027014
申请日:2020-09-21
发明人: Thomas M. SWANICK
IPC分类号: C08F14/26 , C08J5/12 , B32B27/08 , B32B27/32 , B32B3/04 , B29C65/00 , B32B7/02 , B32B27/06 , B29C65/02 , B29C65/82
摘要: A method of making expanded fluoropolymer articles thermally bonds portions of expanded fluoropolymers together, without using an adhesive or crushing force, to produce stronger bonds at the joint between the expanded fluoropolymers than the bonds within the constituent expanded fluoropolymers. The method involves placing the portions of expanded fluoropolymers to be thermally bonded together in intimate contact with each other after wet-stretching the expanded fluoropolymers, and removing the wetting agent used to wet-stretch the expanded fluoropolymers, without subsequent expansion or stretching, to yield an expanded fluoropolymer article exhibiting unexpected and superior properties that can be used in a variety of medical and industrial applications.
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