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公开(公告)号:US20240101810A1
公开(公告)日:2024-03-28
申请号:US17768986
申请日:2020-09-04
发明人: Eun Ho SOHN , Shin Hong YOOK , Hong Suk KANG , In Joon PARK , Sang Goo LEE , Soo Bok LEE , Won Wook SO , Hyeon Jun HEO , Dong Je HAN , Seon Woo KIM
IPC分类号: C08L33/16 , C09D133/16
CPC分类号: C08L33/16 , C09D133/16
摘要: The present invention relates to a composition for forming a composite polymer film, a method for preparing the composition for forming a composite polymer film, a composite polymer film and a method for preparing the composite polymer film. The composition for forming a composite polymer film comprises: a fluorine-based polymer solution comprising a fluorine-based polymer; and polyvinylidene fluoride nanoparticles dispersed in the fluorine-based polymer solution. The method for preparing the composition for forming a composite polymer film comprises the steps of: preparing a fluorine-based polymer solution comprising a fluorine-based polymer; and dispersing polyvinylidene fluoride nanoparticles in the fluorine-based polymer solution. The composite polymer film comprises: a polymer matrix formed from a fluorine-based polymer; and polyvinylidene fluoride nanoparticles dispersed in the polymer matrix. The method for preparing the composite polymer film comprises the steps of: preparing a fluorine-based polymer solution comprising a fluorine-based polymer; preparing a composition, for forming a composite polymer film, by dispersing polyvinylidene fluoride nanoparticles in the fluorine-based polymer solution; and forming the composite polymer film by applying the composition for forming a composite polymer film.
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公开(公告)号:US20240352193A1
公开(公告)日:2024-10-24
申请号:US18575726
申请日:2022-05-27
发明人: Jong Chan WON , Yun Ho KIM , No Kyun PARK , Yu Jin SO , Jin Soo KIM , Jong Min PARK , Sung Mi YOO , Hyun Jin PARK , Hyun Jeong AHN , Jin Ha HA , Sun Kyu KIM , Hyo Eun LEE , Eun Byeol SEO , Eun Bee CHO , Kyung Eun KIM
IPC分类号: C08G73/10
CPC分类号: C08G73/1039
摘要: The present application provides a polyamic acid aqueous solution composition prepared of a polyimide, wherein the composition enables the polymerization of hydrophobic-based monomers into a polyamic acid in water and is improved in transparency, eco-friendliness, storage stability, and the like when cured.
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公开(公告)号:US20240317915A1
公开(公告)日:2024-09-26
申请号:US18579008
申请日:2022-10-19
发明人: Jong Mok PARK , Tae Gyu HWANG , Seo Hyun JUNG , Hoyoul KONG , Yu Jin JUNG , Bogyu LIM , Min Ju JEONG
IPC分类号: C08F220/58 , C08F8/42 , C08F220/30 , C08J5/18
CPC分类号: C08F220/58 , C08F8/42 , C08F220/30 , C08J5/18 , C08J2333/14 , C08J2333/24
摘要: Provided are a copolymer-titanium composite which is crosslinked without a crosslinking agent and an initiator and a copolymer-titanium composite composition including the composite. An organic-inorganic hybrid film produced by including the composition may have a significant refractive index without a large increase in a thickness change rate and may solve a problem of a decrease in optical properties by low dispersibility of a conventional organic-inorganic film by a chemically bonded oxygen-titanium network structure, and an organic film having an excellent refractive index may be provided only with the copolymer.
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4.
公开(公告)号:US20240285778A1
公开(公告)日:2024-08-29
申请号:US18573904
申请日:2022-06-24
发明人: Pil Ho KIM , Sung Yun CHO , Jae Du HA , Chi Hoon PARK , Jong Yeon HWANG , Hyun Jin KIM , Song Hee LEE , Ye Seul LIM , Han Wool KIM , Sun Mi YOO , Beom Seon SUH , Ji Youn PARK , Je Ho RYU , Jung Min AHN , Hee Jung MOON , Ho Hyun LEE
CPC分类号: A61K47/55 , A61K47/545 , A61K47/60
摘要: The present invention relates to a novel heterocyclic compound and a composition, for preventing or treating a cancer, an autoimmune disease, and an inflammatory disease, comprising same. The novel heterocyclic compound of the present invention is a bifunctional compound having a Bruton's tyrosine kinase (BTK) degradation function via a ubiquitin proteasome pathway, and may be utilized as a composition for preventing or treating a cancer, an autoimmune disease, and Parkinson's disease.
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公开(公告)号:US20240246948A1
公开(公告)日:2024-07-25
申请号:US18561855
申请日:2022-05-13
发明人: Seockyong Kang , Daseul Yoon , Hyejeong Kim , Som Yi Park , Dongkyu Kim , Ji-Yeon Park , Yeji Byeon , Hye-Im Jo , Seung Hee Jung , Seong-Il Choi , Seung Chul Lee , Kwangho Lee
IPC分类号: C07D413/14 , A61K31/454 , A61K31/4545 , A61K31/501 , A61K31/506 , A61K31/5377 , A61K45/06 , A61P35/00 , C07D401/12 , C07D401/14 , C07D403/14 , C07D487/08
CPC分类号: C07D413/14 , A61K31/454 , A61K31/4545 , A61K31/501 , A61K31/506 , A61K31/5377 , A61K45/06 , A61P35/00 , C07D401/12 , C07D401/14 , C07D403/14 , C07D487/08
摘要: The present invention relates to a benzamide derivative, a method for preparing same, and a pharmaceutical composition for the prevention or treatment of cancer, containing same as an active ingredient. The benzamide derivative according to an aspect of the present invention can be used in the prevention or treatment of cancer by suppressing EGFR mutation, and, when administered in combination with an EGFR antagonist such as cetuximab, exhibits a significantly synergistic effect on anticancer activity, and thus can be effectively used as an anticancer agent.
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公开(公告)号:US12043910B2
公开(公告)日:2024-07-23
申请号:US16088353
申请日:2017-07-11
发明人: Hyung Ju Kim , Jeehoon Han , Ho Jeong Chae , Jeong-Rang Kim , Soon Yong Jeong , Beom Sik Kim
摘要: The present invention provides an integrated system comprising: an electrocatalysis device, in which an oxidation reaction is carried out at an anode by an electrocatalysis of glycerol, and at a cathode hydrogen is produced through a reduction reaction; and a chemical catalysis device for producing butene oligomers from lignocellulosic biomass through a hydrogenation process, wherein the hydrogen produced by the electrocatalysis device is used for the production of the butene oligomers by the chemical catalysis device, and a thermal energy of the electrocatalysis device and the chemical catalysis device is exchanged with each other. The integrated system according to the present invention can reduce the cost of materials of a process for preparing butene oligomers by using hydrogen, which is a byproduct of a process for preparing glycerol derivatives, as a material of a process for preparing the butene oligomers through the integration of materials and energy from the processes for preparing glycerol derivatives and butene oligomers, and can obtain an effect of reducing energy costs by greatly reducing energy required in an integrated process by supplying, as a part of a thermal energy required at the process for preparing glycerol derivatives, the waste heat of the process for preparing the butene oligomers through the construction of a thermal energy integration network.
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公开(公告)号:US20240141289A1
公开(公告)日:2024-05-02
申请号:US18547750
申请日:2021-04-21
发明人: Han-Jin PARK , Hyemin KIM , Ilkyun IM , Ji-Woo KIM
IPC分类号: C12N5/0735 , C12N5/00
CPC分类号: C12N5/0606 , C12N5/0018 , C12N2500/24
摘要: The present invention relates to a method for constructing a human pluripotent stem cell-derived liver organoid having enhanced drug metabolic potentials and a liver organoid constructed by the method. Because differentiation is made from human induced pluripotent stem cells dedifferentiated from somatic cells of patients, the cells are easily supplied so that patient-specific liver organoids can be prepared. The organoids can similarly simulate the real human liver structure because they consist of hepatocytes, cholangiocytes, gallbladder cells, and microduct structures, have excellent expression and functions of drug metabolism enzymes, and exhibit drug toxicity, drug metabolic capability, and drug-induced cardiotoxicity. Thus, the organoids can be advantageously used as liver models for searching for pathogenesis of liver diseases and for evaluating drug stability.
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8.
公开(公告)号:US20240125991A1
公开(公告)日:2024-04-18
申请号:US18378233
申请日:2023-10-10
申请人: POSTECH Research and Business Development Foundation , KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
发明人: Young-Ki Kim , Jun-Hyung Im , Yeongseon Choi , Bogyu Lim , Yejin Kim , Seungju Jeon , Kwang Hun Park
IPC分类号: G02B5/26
CPC分类号: G02B5/26
摘要: Disclosed is a transmissive wavelength tunable hyperspectral filter using layered twisted liquid crystal thin film, wherein the transmissive wavelength tunable hyperspectral filter is formed by laminating two or more layered twisted liquid crystal thin films having different broadband reflection bandgaps, wherein each of the layered twisted liquid crystal thin films includes a twisted liquid crystal layer including a plurality of unit liquid crystal molecules, and formed by arranging twisted liquid crystal complexes defining a preset cone angle along the helical axis with respect to the helical axis, and includes a pseudo-layer formed by arranging a plurality of twisted liquid crystal layers in a lengthwise direction of the helical axis at a preset inter-layer pitch (P).
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公开(公告)号:US11952345B2
公开(公告)日:2024-04-09
申请号:US17892212
申请日:2022-08-22
发明人: Jihui Seo , Jaeyong Lee , Pyung Soon Kim , Jin Woo Choung , Yongwoo Kim , Ji Hoon Park , Soo Min Kim , Jeong Jae Lee , Kwanyong Jeong
IPC分类号: C07D213/53
CPC分类号: C07D213/53
摘要: Provided is a method for synthesizing bipyridine that includes performing a dimerization reaction of a reactant including a piperidine-based compound, a pyridine-based compound, or a mixture thereof in the presence of a catalyst in which an active metal is supported on a composite metal oxide support including silica (SiO2) and alumina (Al2O3).
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10.
公开(公告)号:US20240075468A1
公开(公告)日:2024-03-07
申请号:US18118509
申请日:2023-03-07
发明人: Chae Hwan Hong , Hyeon Gook Kim
IPC分类号: B01J38/62 , B01J6/00 , B01J23/36 , B01J23/44 , B01J23/92 , B01J23/96 , B01J38/02 , B01J38/64 , B01J38/68
CPC分类号: B01J38/62 , B01J6/001 , B01J23/36 , B01J23/44 , B01J23/92 , B01J23/96 , B01J38/02 , B01J38/64 , B01J38/68
摘要: Disclosed is a method of recovering a metal catalyst during production of an adipic acid from glucose. The method of recovering and the metal catalyst may provide economic feasibility of the adipic acid production process.
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