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公开(公告)号：US07875438B2
公开(公告)日：2011-01-25
申请号：US12001437
申请日：2007-12-11
CPC分类号： C07K14/3156 , A61K31/7052 , A61K39/00 , A61K39/092 , A61K2039/53 , C07H21/02 , C07H21/04 , C07K14/315 , Y02A50/472
摘要： The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.
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2.发明申请Nucleic Acid And Amino Acid Sequences Relating To Streptococcus Pneumoniae For Diagnostics And Therapeutics 审中-公开与肺炎链球菌相关的核酸和氨基酸序列用于诊断和治疗公开(公告)号：US20140255443A1
公开(公告)日：2014-09-11
申请号：US14097707
申请日：2013-12-05
IPC分类号： C07K14/315
CPC分类号： C07K14/3156 , A61K31/7052 , A61K39/00 , A61K39/092 , A61K2039/53 , C07H21/02 , C07H21/04 , C07K14/315
摘要： The invention provides methods of treating subject with polypeptides having at least 80% identity to SEQ ID NO: 5326. The methods stimulate an immune response in the subject and provide methods for prevention and treatment of pathological conditions resulting from bacterial infection.
摘要翻译： 本发明提供了用与SEQ ID NO：5326具有至少80％同一性的多肽治疗受试者的方法。该方法刺激受试者的免疫应答并提供预防和治疗由细菌感染引起的病理状况的方法。
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公开(公告)号：US08293249B2
公开(公告)日：2012-10-23
申请号：US11796426
申请日：2007-04-27
IPC分类号： A61K39/09 , C07K14/195
CPC分类号： C07K14/3156 , A61K31/7052 , A61K39/00 , A61K39/092 , A61K2039/53 , C07H21/02 , C07H21/04 , C07K14/315 , Y02A50/472
摘要： The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.
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4.发明授权Nucleic acid and amino acid sequences relating to streptococcus pneumoniae for diagnostics and therapeutics 失效与肺炎链球菌相关的核酸和氨基酸序列用于诊断和治疗公开(公告)号：US07875437B2
公开(公告)日：2011-01-25
申请号：US12001413
申请日：2007-12-11
CPC分类号： C07K14/3156 , A61K31/7052 , A61K39/00 , A61K39/092 , A61K2039/53 , C07H21/02 , C07H21/04 , C07K14/315 , Y02A50/472
摘要： The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.
摘要翻译： 本发明提供了分离的多肽和源自肺炎链球菌的核酸序列，其可用于诊断和治疗病理状况; 针对多肽的抗体; 以及用于制备多肽的方法。 本发明还提供了用于检测，预防和治疗由细菌感染引起的病理状况的方法。
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公开(公告)号：US20080131964A1
公开(公告)日：2008-06-05
申请号：US12001752
申请日：2007-12-12
CPC分类号： C07K14/3156 , A61K31/7052 , A61K39/00 , A61K39/092 , A61K2039/53 , C07H21/02 , C07H21/04 , C07K14/315 , Y02A50/472
摘要： The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.
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6.发明申请公开(公告)号：US20130078271A1
公开(公告)日：2013-03-28
申请号：US13613827
申请日：2012-09-13
IPC分类号： A61K39/09
CPC分类号： C07K14/3156 , A61K31/7052 , A61K39/00 , A61K39/092 , A61K2039/53 , C07H21/02 , C07H21/04 , C07K14/315 , Y02A50/472
摘要： The invention provides methods of treating subject with polypeptides having at least 80% identity to SEQ ID NO: 5326. The methods stimulate an immune response in the subject and provide methods for prevention and treatment of pathological conditions resulting from bacterial infection.
摘要翻译： 本发明提供了用与SEQ ID NO：5326具有至少80％同一性的多肽治疗受试者的方法。该方法刺激受试者的免疫应答并提供预防和治疗由细菌感染引起的病理状况的方法。
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公开(公告)号：US07867501B2
公开(公告)日：2011-01-11
申请号：US11524943
申请日：2006-09-21
IPC分类号： A61K39/09 , C07K14/195 , C07H21/04 , C12P21/04
CPC分类号： C07K14/3156 , A61K31/7052 , A61K39/00 , A61K39/092 , A61K2039/53 , C07H21/02 , C07H21/04 , C07K14/315 , Y02A50/472
摘要： The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.
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8.发明申请Nucleic acid and amino acid sequences relating to streptococcus pneumoniae for diagnostics and therapeutics 有权与肺炎链球菌相关的核酸和氨基酸序列用于诊断和治疗公开(公告)号：US20090148890A1
公开(公告)日：2009-06-11
申请号：US11803132
申请日：2007-05-11
IPC分类号： C12P21/00
CPC分类号： C07K14/3156 , A61K31/7052 , A61K39/00 , A61K39/092 , A61K2039/53 , C07H21/02 , C07H21/04 , C07K14/315 , Y02A50/472
摘要： The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.
摘要翻译： 本发明提供了分离的多肽和源自肺炎链球菌的核酸序列，其可用于诊断和治疗病理状况; 针对多肽的抗体; 以及用于制备多肽的方法。 本发明还提供了用于检测，预防和治疗由细菌感染引起的病理状况的方法。
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公开(公告)号：US20080124794A1
公开(公告)日：2008-05-29
申请号：US12001437
申请日：2007-12-11
CPC分类号： C07K14/3156 , A61K31/7052 , A61K39/00 , A61K39/092 , A61K2039/53 , C07H21/02 , C07H21/04 , C07K14/315 , Y02A50/472
摘要： The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.
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