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公开(公告)号：US20170284910A1
公开(公告)日：2017-10-05
申请号：US15632226
申请日：2017-06-23
发明人： Nolan Orfield , Collin Rich , Vincent Alessi
CPC分类号： G01N1/36 , G01N1/06 , G01N1/2813 , G01N1/312 , G01N1/44 , G01N35/00029 , G01N35/00732 , G01N35/00871 , G01N2001/061 , G01N2035/00039 , G01N2035/00138 , G01N2035/00831
摘要： A system and method for mounting a section onto a substrate, the system comprising: a fluid channel including: a fluid channel inlet that receives the section, processed from a bulk embedded sample by a sample sectioning module positioned proximal the fluid channel inlet, a section-mounting region downstream of the fluid channel inlet, and a fluid channel outlet downstream of the section-mounting region; a reservoir in fluid communication with the fluid channel outlet; and a manifold, fluidly coupled to the reservoir, that delivers fluid from the reservoir to the fluid channel inlet, thereby transmitting fluid flow that drives delivery of the section from the fluid channel inlet toward the section-mounting region.
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公开(公告)号：US20150241324A1
公开(公告)日：2015-08-27
申请号：US14706479
申请日：2015-05-07
发明人： Nolan Orfield , Collin Rich , Vincent Alessi
CPC分类号： G01N1/36 , G01N1/06 , G01N1/2813 , G01N1/312 , G01N1/44 , G01N35/00029 , G01N35/00732 , G01N35/00871 , G01N2001/061 , G01N2035/00039 , G01N2035/00138 , G01N2035/00831
摘要： A system and method for mounting a section onto a substrate, the system comprising: a fluid channel including: a fluid channel inlet that receives the section, processed from a bulk embedded sample by a sample sectioning module positioned proximal the fluid channel inlet, a section-mounting region downstream of the fluid channel inlet, and a fluid channel outlet downstream of the section-mounting region; a reservoir in fluid communication with the fluid channel outlet; and a manifold, fluidly coupled to the reservoir, that delivers fluid from the reservoir to the fluid channel inlet, thereby transmitting fluid flow that drives delivery of the section from the fluid channel inlet toward the section-mounting region.
摘要翻译： 一种用于将截面安装在基底上的系统和方法，所述系统包括：流体通道，其包括：流体通道入口，其接收通过位于流体通道入口附近的样品分段模块从大块嵌入样品处理的部分， 在流体通道入口下游的安装区域和在区段安装区域下游的流体通道出口; 与流体通道出口流体连通的储存器; 以及歧管，其流体地联接到储存器，其将流体从储存器输送到流体通道入口，从而传输流体流动，其驱动区段从流体通道入口向区段安装区域的输送。
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公开(公告)号：US20150226951A1
公开(公告)日：2015-08-13
申请号：US14696096
申请日：2015-04-24
发明人： Vincent Alessi
摘要： One embodiment includes a system for mounting a specimen on a slide, the system having an immersion chamber, a stage, and a pump. The immersion chamber is configured to hold a liquid and comprises at least one wall, a closed bottom, and an open top. The stage is configured to support the slide, and the stage is arranged within the immersion chamber such that the specimen may be supported substantially above the stage by the liquid. The pump is configured to draw the liquid from the immersion chamber such that the level of liquid in the immersion chamber decreases and the specimen is dispensed onto the slide.
摘要翻译： 一个实施例包括用于将样本安装在载玻片上的系统，该系统具有浸没室，台和泵。 浸没室被构造成保持液体并且包括至少一个壁，封闭底部和敞开的顶部。 该台被构造成支撑滑块，并且台架布置在浸没室内，使得样本可以被液体基本上支撑在舞台上方。 泵被配置为从浸没室中抽出液体，使得浸没室中的液体水平降低，并将样品分配到载玻片上。
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公开(公告)号：US09057671B1
公开(公告)日：2015-06-16
申请号：US14574217
申请日：2014-12-17
发明人： Nolan Orfield , Collin Rich , Vincent Alessi
CPC分类号： G01N1/36 , G01N1/06 , G01N1/2813 , G01N1/312 , G01N1/44 , G01N35/00029 , G01N35/00732 , G01N35/00871 , G01N2001/061 , G01N2035/00039 , G01N2035/00138 , G01N2035/00831
摘要： A system and method for mounting a section onto a substrate, the system comprising: a fluid channel including: a fluid channel inlet that receives the section, processed from a bulk embedded sample by a sample sectioning module positioned proximal the fluid channel inlet, a section-mounting region downstream of the fluid channel inlet, and a fluid channel outlet downstream of the section-mounting region; a reservoir in fluid communication with the fluid channel outlet; and a manifold, fluidly coupled to the reservoir, that delivers fluid from the reservoir to the fluid channel inlet, thereby transmitting fluid flow that drives delivery of the section from the fluid channel inlet toward the section-mounting region.
摘要翻译： 一种用于将截面安装在基底上的系统和方法，所述系统包括：流体通道，其包括：流体通道入口，其接收通过位于流体通道入口附近的样品分段模块从大块嵌入样品处理的部分， 在流体通道入口下游的安装区域和在区段安装区域下游的流体通道出口; 与流体通道出口流体连通的储存器; 以及歧管，其流体地联接到储存器，其将流体从储存器输送到流体通道入口，从而传输流体流动，其驱动区段从流体通道入口向区段安装区域的输送。
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公开(公告)号：US09719897B2
公开(公告)日：2017-08-01
申请号：US15131993
申请日：2016-04-18
发明人： Nolan Orfield , Collin Rich , Vincent Alessi
CPC分类号： G01N1/36 , G01N1/06 , G01N1/2813 , G01N1/312 , G01N1/44 , G01N35/00029 , G01N35/00732 , G01N35/00871 , G01N2001/061 , G01N2035/00039 , G01N2035/00138 , G01N2035/00831
摘要： A system and method for mounting a section onto a substrate, the system comprising: a fluid channel including: a fluid channel inlet that receives the section, processed from a bulk embedded sample by a sample sectioning module positioned proximal the fluid channel inlet, a section-mounting region downstream of the fluid channel inlet, and a fluid channel outlet downstream of the section-mounting region; a reservoir in fluid communication with the fluid channel outlet; and a manifold, fluidly coupled to the reservoir, that delivers fluid from the reservoir to the fluid channel inlet, thereby transmitting fluid flow that drives delivery of the section from the fluid channel inlet toward the section-mounting region.
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公开(公告)号：US09658441B2
公开(公告)日：2017-05-23
申请号：US14702990
申请日：2015-05-04
发明人： Vincent Alessi
摘要： A system and method for mounting a specimen on a slide, the system having an immersion chamber, a stage, a transducer, and a pump. The immersion chamber is configured to hold a liquid and includes at least one wall, a closed bottom, and an open top. The stage is configured to support the slide, and the stage is arranged within the immersion chamber such that the specimen may be supported substantially above the stage by the liquid. The transducer is configured to induce a wave in the liquid in the immersion chamber such that the wave alters the motion of the specimen. The pump is configured to draw the liquid from the immersion chamber such that the level of liquid in the immersion chamber decreases and the specimen is dispensed onto the slide.
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公开(公告)号：US10175155B2
公开(公告)日：2019-01-08
申请号：US15632226
申请日：2017-06-23
发明人： Nolan Orfield , Collin Rich , Vincent Alessi
摘要： A system and method for mounting a section onto a substrate, the system comprising: a fluid channel including: a fluid channel inlet that receives the section, processed from a bulk embedded sample by a sample sectioning module positioned proximal the fluid channel inlet, a section-mounting region downstream of the fluid channel inlet, and a fluid channel outlet downstream of the section-mounting region; a reservoir in fluid communication with the fluid channel outlet; and a manifold, fluidly coupled to the reservoir, that delivers fluid from the reservoir to the fluid channel inlet, thereby transmitting fluid flow that drives delivery of the section from the fluid channel inlet toward the section-mounting region.
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公开(公告)号：US20150168276A1
公开(公告)日：2015-06-18
申请号：US14574217
申请日：2014-12-17
发明人： Nolan Orfield , Collin Rich , Vincent Alessi
IPC分类号： G01N1/28
CPC分类号： G01N1/36 , G01N1/06 , G01N1/2813 , G01N1/312 , G01N1/44 , G01N35/00029 , G01N35/00732 , G01N35/00871 , G01N2001/061 , G01N2035/00039 , G01N2035/00138 , G01N2035/00831
摘要： A system and method for mounting a section onto a substrate, the system comprising: a fluid channel including: a fluid channel inlet that receives the section, processed from a bulk embedded sample by a sample sectioning module positioned proximal the fluid channel inlet, a section-mounting region downstream of the fluid channel inlet, and a fluid channel outlet downstream of the section-mounting region; a reservoir in fluid communication with the fluid channel outlet; and a manifold, fluidly coupled to the reservoir, that delivers fluid from the reservoir to the fluid channel inlet, thereby transmitting fluid flow that drives delivery of the section from the fluid channel inlet toward the section-mounting region.
摘要翻译： 一种用于将截面安装在基底上的系统和方法，所述系统包括：流体通道，其包括：流体通道入口，其接收通过位于流体通道入口附近的样品分段模块从大块嵌入样品处理的部分， 在流体通道入口下游的安装区域和在区段安装区域下游的流体通道出口; 与流体通道出口流体连通的储存器; 以及歧管，其流体地联接到储存器，其将流体从储存器输送到流体通道入口，从而传输流体流动，其驱动区段从流体通道入口向区段安装区域的输送。
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公开(公告)号：US09915816B2
公开(公告)日：2018-03-13
申请号：US14696096
申请日：2015-04-24
发明人： Vincent Alessi
摘要： One embodiment includes a system for mounting a specimen on a slide, the system having an immersion chamber, a stage, and a pump. The immersion chamber is configured to hold a liquid and includes at least one wall, a closed bottom, and an open top. The stage is configured to support the slide, and the stage is arranged within the immersion chamber such that the specimen may be supported substantially above the stage by the liquid. The pump is configured to draw the liquid from the immersion chamber such that the level of liquid in the immersion chamber decreases and the specimen is dispensed onto the slide.
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公开(公告)号：US20170329119A9
公开(公告)日：2017-11-16
申请号：US14696096
申请日：2015-04-24
发明人： Vincent Alessi
摘要： One embodiment includes a system for mounting a specimen on a slide, the system having an immersion chamber, a stage, and a pump. The immersion chamber is configured to hold a liquid and comprises at least one wall, a closed bottom, and an open top. The stage is configured to support the slide, and the stage is arranged within the immersion chamber such that the specimen may be supported substantially above the stage by the liquid. The pump is configured to draw the liquid from the immersion chamber such that the level of liquid in the immersion chamber decreases and the specimen is dispensed onto the slide.
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