Method and system for adaptive physical design
    1.
    发明授权
    Method and system for adaptive physical design 有权
    自适应物理设计方法与系统

    公开(公告)号:US08572541B2

    公开(公告)日:2013-10-29

    申请号:US12876138

    申请日:2010-09-05

    IPC分类号: G06F17/50

    CPC分类号: G06F17/5072 G06F2217/02

    摘要: A method is provided that includes performing a free placement of a system design comprising a plurality of power domains, wherein the power domains are not constrained to physical regions, assigning a physical region to each of the power domains based on the free placement of cells in the power domains, performing a soft cluster placement of the system design with each power domain and corresponding physical region defined as a soft cluster, refining at least one physical region based on the soft cluster placement, redefining cells in at least one power domain based on the soft cluster placement of the cells and the corresponding physical region, and performing a hard cluster placement of the system design with each power domain and corresponding physical region defined as a hard cluster to generate final power domains.

    摘要翻译: 提供了一种方法,其包括执行包括多个功率域的系统设计的自由放置,其中所述功率域不被约束到物理区域,基于所述功率域中的单元的自由放置来为每个功率域分配物理区域 功率域,执行具有每个功率域的系统设计的软集群布置以及被定义为软集群的相应物理区域,基于所述软集群布置来改进至少一个物理区域,基于所述软集群布置重新定义至少一个电源域中的小区,基于 单元的软集群放置和相应的物理区域,以及执行与每个功率域的系统设计的硬集群放置以及被定义为硬集群的对应的物理区域以产生最终的电力域。

    Composite metastasis score with weighted coefficients for predicting breast cancer metastasis, and uses thereof
    2.
    发明授权
    Composite metastasis score with weighted coefficients for predicting breast cancer metastasis, and uses thereof 有权
    复合转移评分与预测乳腺癌转移的加权系数及其用途

    公开(公告)号:US08557525B1

    公开(公告)日:2013-10-15

    申请号:US13406221

    申请日:2012-02-27

    IPC分类号: C12Q1/68

    CPC分类号: C12Q1/6886 C12Q2600/158

    摘要: The present invention relates to a composite metastasis score (“cMS”) based on expression of a 14-gene molecular signature (referred to as a metastasis score, or “MS”) in combination with progesterone receptor (PR) expression that is useful for predicting breast cancer metastasis. In preferred embodiments, the cMS is determined by applying weighted coefficients to MS and PR. The present invention provides methods and reagents for detecting and profiling the expression levels of these genes, and methods of using the expression level information for predicting risk of breast cancer metastasis, among other embodiments.

    摘要翻译: 本发明涉及基于14基因分子特征(称为转移分数或称“MS”)与孕激素受体(PR)表达的组合的复合转移评分(“cMS”),其可用于 预测乳腺癌转移。 在优选实施例中,通过将加权系数应用于MS和PR来确定cMS。 本发明提供了用于检测和分析这些基因的表达水平的方法和试剂,以及用于预测乳腺癌转移风险的表达水平信息的方法。

    Memory Power Management Systems and Methods
    3.
    发明申请
    Memory Power Management Systems and Methods 有权
    内存电源管理系统和方法

    公开(公告)号:US20100103760A1

    公开(公告)日:2010-04-29

    申请号:US12258747

    申请日:2008-10-27

    IPC分类号: G11C5/14 G11C8/00

    CPC分类号: G11C5/147

    摘要: Memory power management systems and methods are provided. One embodiment of the present invention includes a memory power management system. The system comprises a first low dropout (LDO) regulator that provides an active operating voltage that is derived from a first supply voltage to power a memory array during an active mode. The system further comprises a second LDO regulator that provides a minimum memory retention voltage that is derived from a second supply voltage to power the memory array in a standby mode, wherein the second supply voltage also powers at least one peripheral circuit for reading from and/or writing to the memory array.

    摘要翻译: 提供了内存电源管理系统和方法。 本发明的一个实施例包括存储器电源管理系统。 该系统包括第一低压差(LDO)调节器,其提供从第一电源电压导出的有源工作电压,以在激活模式期间为存储器阵列供电。 该系统还包括第二LDO调节器,其提供从第二电源电压导出的最低存储器保持电压,以在待机模式下为存储器阵列供电,其中第二电源电压还为至少一个外围电路供电以从其读取和/ 或写入存储器阵列。

    Molecular prognostic signature for predicting breast cancer distant metastasis, and uses thereof
    5.
    发明申请
    Molecular prognostic signature for predicting breast cancer distant metastasis, and uses thereof 有权
    用于预测乳腺癌远处转移的分子预后特征及其用途

    公开(公告)号:US20080206769A1

    公开(公告)日:2008-08-28

    申请号:US12012530

    申请日:2008-01-31

    申请人: Kit Lau Alice Wang

    发明人: Kit Lau Alice Wang

    IPC分类号: C12Q1/68 C40B40/06

    摘要: The present invention is based on the discovery of a unique 14-gene molecular prognostic signature that is useful for predicting breast cancer metastasis. In particular, the present invention relates to methods and reagents for detecting and profiling the expression levels of these genes, and methods of using the expression level information in predicting risk of breast cancer metastasis.

    摘要翻译: 本发明基于发现可用于预测乳腺癌转移的独特的14基因分子预后特征。 特别地,本发明涉及用于检测和分析这些基因的表达水平的方法和试剂,以及在预测乳腺癌转移风险中使用表达水平信息的方法。

    Fast access memory architecture
    6.
    发明申请
    Fast access memory architecture 有权
    快速访问内存架构

    公开(公告)号:US20070223294A1

    公开(公告)日:2007-09-27

    申请号:US11385151

    申请日:2006-03-21

    IPC分类号: G11C7/00

    CPC分类号: G11C8/10

    摘要: A computer system comprising a control logic and a storage coupled to the control logic. The storage comprises a plurality of bitcells and bitlines used to transfer data between the control logic and the bitcells. The control logic provides an address of a target bitcell to the storage. Within a single clock cycle, the storage uses the address to activate the target bitcell, to precharge bitlines coupled to the target bitcell, and to access the target bitcell.

    摘要翻译: 一种包括控制逻辑和耦合到控制逻辑的存储器的计算机系统。 存储器包括用于在控制逻辑和位单元之间传送数据的多个比特单元和位线。 控制逻辑向存储器提供目标位单元的地址。 在单个时钟周期内,存储器使用地址来激活目标比特单元,以预先耦合到目标比特单元的位线,并访问目标比特单元。

    MOLECULAR PROGNOSTIC SIGNATURE FOR PREDICTING BREAST CANCER METASTASIS, AND USES THEREOF
    7.
    发明申请
    MOLECULAR PROGNOSTIC SIGNATURE FOR PREDICTING BREAST CANCER METASTASIS, AND USES THEREOF 有权
    用于预测乳腺癌的分子预防标志及其用途

    公开(公告)号:US20100323921A1

    公开(公告)日:2010-12-23

    申请号:US12638040

    申请日:2009-12-15

    申请人: Kit LAU Alice WANG

    发明人: Kit LAU Alice WANG

    IPC分类号: C40B40/06 C12Q1/68

    摘要: The present invention is based on the discovery of a unique 14-gene molecular prognostic signature that is useful for predicting breast cancer metastasis. In particular, the present invention relates to methods and reagents for detecting and profiling the expression levels of these genes, and methods of using the expression level information in predicting risk of breast cancer metastasis.

    摘要翻译: 本发明基于发现可用于预测乳腺癌转移的独特的14基因分子预后特征。 特别地,本发明涉及用于检测和分析这些基因表达水平的方法和试剂,以及在预测乳腺癌转移风险中使用表达水平信息的方法。

    Adaptive voltage control for performance and energy optimization
    8.
    发明申请
    Adaptive voltage control for performance and energy optimization 有权
    用于性能和能量优化的自适应电压控制

    公开(公告)号:US20050194592A1

    公开(公告)日:2005-09-08

    申请号:US11045222

    申请日:2005-01-28

    IPC分类号: H01L29/04

    CPC分类号: G11C5/147

    摘要: A device for adaptively controlling a voltage supplied to circuitry in substantially close proximity to the device, comprising a processing module, a first tracking element coupled to the processing module and producing a first value indicative of a first estimated speed associated with the circuitry, and a second tracking element coupled to the processing module and producing a second value indicative of a second estimated speed associated with the circuitry. The processing module compares each of the first and second values to a target value and causes a voltage output to be adjusted based on said comparison.

    摘要翻译: 一种用于自适应地控制提供给基本上靠近设备的电路的电压的装置,包括处理模块,耦合到处理模块的第一跟踪元件,并产生指示与电路相关联的第一估计速度的第一值,以及 第二跟踪元件耦合到所述处理模块并产生指示与所述电路相关联的第二估计速度的第二值。 处理模块将第一和第二值中的每一个与目标值进行比较,并且基于所述比较使电压输出被调整。

    Molecular prognostic signature for predicting breast cancer metastasis, and uses thereof
    9.
    发明授权
    Molecular prognostic signature for predicting breast cancer metastasis, and uses thereof 有权
    用于预测乳腺癌转移的分子预后特征及其用途

    公开(公告)号:US08614058B2

    公开(公告)日:2013-12-24

    申请号:US12638040

    申请日:2009-12-15

    申请人: Kit Lau Alice Wang

    发明人: Kit Lau Alice Wang

    IPC分类号: C12Q1/68

    摘要: The present invention is based on the discovery of a unique 14-gene molecular prognostic signature that is useful for predicting breast cancer metastasis. In particular, the present invention relates to methods and reagents for detecting and profiling the expression levels of these genes, and methods of using the expression level information in predicting risk of breast cancer metastasis.

    摘要翻译: 本发明基于发现可用于预测乳腺癌转移的独特的14基因分子预后特征。 特别地,本发明涉及用于检测和分析这些基因的表达水平的方法和试剂,以及在预测乳腺癌转移风险中使用表达水平信息的方法。

    Apparatus, system and method of power state control
    10.
    发明授权
    Apparatus, system and method of power state control 有权
    电力状态控制的装置,系统和方法

    公开(公告)号:US08051313B2

    公开(公告)日:2011-11-01

    申请号:US12110589

    申请日:2008-04-28

    CPC分类号: H03K3/0375

    摘要: An apparatus, system and method for asynchronously reducing power in a power domain. In one embodiment, the method includes: (1) receiving a sleep command for the power domain, (2) receiving, upon receiving the sleep command, an affirmative retention status signal denoting that a retention area in the power domain has stored data, (3) receiving, upon receiving the sleep command, an affirmative isolation status signal that denotes that an isolation of the power domain has occurred and (4) providing a power domain off command to the power domain upon receiving at least the sleep command, the affirmative status retention signal and the affirmative status isolation signal. In another embodiment, multiple enable signals are employed to generate a “glitch-free” control for a power switch.

    摘要翻译: 用于在电力域中异步降低功率的装置,系统和方法。 在一个实施例中,该方法包括:(1)接收功率域的睡眠命令,(2)在接收到睡眠命令时接收表示功率域中的保留区域已存储数据的肯定保持状态信号( 3)在接收到睡眠命令时接收表示已经发生功率域隔离的肯定隔离状态信号,以及(4)至少在接收到睡眠命令时向功率域提供功率域关闭命令,肯定的 状态保持信号和肯定状态隔离信号。 在另一个实施例中,采用多个使能信号来产生功率开关的“无毛刺”控制。