-
1.发明申请INDUCED PLURIPOTENT STEM CELL GENERATION USING TWO FACTORS AND P53 INACTIVATION 审中-公开使用两个因子和P53失活诱导的PLUIPOTETI干细胞生成公开(公告)号：US20120076762A1
公开(公告)日：2012-03-29
申请号：US13259644
申请日：2010-03-24
申请人： Teruhisa Kawamura , Jotaro Suzuki , Yunyuan V. Wang , Angel Raya , Geoffrey M. Wahl , Juan Carlos Izpisua Belmonte
发明人： Teruhisa Kawamura , Jotaro Suzuki , Yunyuan V. Wang , Angel Raya , Geoffrey M. Wahl , Juan Carlos Izpisua Belmonte
CPC分类号： C12N5/0696 , C12N2501/40 , C12N2501/602 , C12N2501/603 , C12N2501/998 , C12N2510/00
摘要： Methods and compositions are provided for, inter alia, the generation of induced pluripotent stem cells. Induced pluripotent stem cells may be generated by reprogramming and inhibition of p53. Further, useful intermediates for the generation of induced pluripotent stem cells are also provided.
摘要翻译： 提供方法和组合物，尤其是诱导多能干细胞的产生。 诱导的多能干细胞可通过重编程和抑制p53产生。 此外，还提供了用于产生诱导多能干细胞的有用中间体。
-
公开(公告)号：US20120121549A1
公开(公告)日：2012-05-17
申请号：US13292014
申请日：2011-11-08
申请人： ANGEL RAYA , TROND AASEN , JUAN CARLOS I. BELMONTE
发明人： ANGEL RAYA , TROND AASEN , JUAN CARLOS I. BELMONTE
CPC分类号： C12N5/0696 , C12N2501/602 , C12N2501/603 , C12N2501/604 , C12N2501/606 , C12N2506/094 , C12N2510/00
摘要： The invention relates to the field of stem cells and, specially, to the reprogramming of adult somatic cells; to obtain pluripotent cells by the transfection of specific genes. Thus, the invention provides induced pluripotent stem cells (iPS) and methods of obtaining and using them.
摘要翻译： 本发明涉及干细胞领域，特别涉及成体细胞的重编程; 通过转染特定基因获得多能细胞。 因此，本发明提供诱导性多能干细胞（iPS）及其获得和使用方法。
-
公开(公告)号：US20120189595A1
公开(公告)日：2012-07-26
申请号：US13120727
申请日：2009-09-25
IPC分类号： A61K35/12 , C12N15/867 , A61P17/00 , C12N5/10 , C12N15/85
CPC分类号： C12N5/0696 , C12N2501/602 , C12N2501/603 , C12N2501/604 , C12N2501/606 , C12N2506/094 , C12N2510/00
摘要： The invention relates to the field of stem cells and, specially, to the reprogramming of adult somatic cells; to obtain pluripotent cells by the transfection of specific genes. Thus, the invention provides induced pluripotent stem cells (iPS) and methods of obtaining and using them.
-
4.发明申请Generation of Genetically Corrected Disease-free Induced Pluripotent Stem Cells 审中-公开遗传修复无病诱导多能干细胞的生成公开(公告)号：US20100303775A1
公开(公告)日：2010-12-02
申请号：US12789375
申请日：2010-05-27
CPC分类号： A61K48/005 , C12N5/0696 , C12N15/873 , C12N2501/602 , C12N2501/603 , C12N2501/604 , C12N2501/606 , C12N2501/727 , C12N2510/00 , C12N2799/027 , C12N2830/60
摘要： Methods and compositions for the generation and use of genetically corrected induced pluripotent stem cells are provided.
摘要翻译： 提供了用于产生和使用遗传修饰的诱导多能干细胞的方法和组合物。
-
-
-
搜索结果
4 条记录 (耗时 0.014 秒)
