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    Disease indications for selective endobronchial lung region isolation
    2.
    发明申请
    Disease indications for selective endobronchial lung region isolation 审中-公开
    选择性支气管肺区隔离的疾病适应症

    公开(公告)号：US20050178389A1

    公开(公告)日：2005-08-18

    申请号：US11044875

    申请日：2005-01-26

    申请人： David Shaw ,  John McCutcheon ,  Antony Fields

    发明人： David Shaw ,  John McCutcheon ,  Antony Fields

    IPC分类号： A61F2/04 ,  A61F2/24 ,  A61F2/82 ,  A61M11/00 ,  A61M16/00

    CPC分类号： A61F2/04 ,  A61B17/12036 ,  A61B17/12104 ,  A61B17/12159 ,  A61B17/12172 ,  A61F2/24 ,  A61F2/82 ,  A61F2002/043

    摘要： Disclosed are various disease indications and treatment methods that benefit from selective lung region isolation. A lung region is bronchially isolated by regulating the flow of fluid to and from the lung region, such as by implanting one or more bronchial isolation devices into one or more bronchial passageways that feed air to the lung region. The bronchial isolation devices can comprise, for example, one-way valves, two-way valves, occluders or blockers, ligating clips, glues, sealants, and sclerosing agents.

    摘要翻译： 公开了从选择性肺区域分离中受益的各种疾病适应症和治疗方法。 通过调节流入和流出肺部区域的流体的流动，例如通过将一个或多个支气管隔离装置植入一个或多个向肺部区域进食空气的支气管通道，肺部区域被支气管分离。 支气管隔离装置可以包括例如单向阀，双向阀，闭塞器或阻塞器，结扎夹，胶水，密封剂和硬化剂。

    Methods and devices for blocking flow through collateral pathways in the lung
    7.
    发明申请
    Methods and devices for blocking flow through collateral pathways in the lung 有权
    阻止流经肺部旁路的方法和装置

    公开(公告)号：US20050196344A1

    公开(公告)日：2005-09-08

    申请号：US11067025

    申请日：2005-02-25

    申请人： John McCutcheon ,  Antony Fields ,  David Shaw

    发明人： John McCutcheon ,  Antony Fields ,  David Shaw

    IPC分类号： A61L9/04 ,  A61M11/00

    CPC分类号： A61F5/00 ,  A61M11/00 ,  A61M16/0406 ,  A61M16/208 ,  A61M2210/1039

    摘要： Disclosed is a method of regulating fluid flow for a targeted lung region. The method comprises injecting a therapeutic agent into the targeted lung region. The therapeutic agent induces a reaction in lung tissue of the targeted lung region or in a collateral pathway to the lung region to reduce collateral fluid flow into the targeted lung region. In one aspect, the method additionally comprises deploying a bronchial isolation device in the direct pathway to regulate fluid flow to the targeted lung region through the direct pathway. The therapeutic agent can comprise, for example, a sclerosing agent that induces a reaction that causes sclerosis in the lung tissue.

    摘要翻译： 公开了一种调节目标肺部区域的流体流动的方法。 该方法包括将治疗剂注入靶向的肺部区域。 治疗剂诱导靶向肺部区域的肺组织或到肺部区域的旁路途径中的反应，以减少侧流体流入靶向肺区域。 在一个方面，该方法还包括在直接通路中部署支气管隔离装置，以通过直接通路调节流向目标肺区域的流体。 治疗剂可以包含例如诱导引起肺组织中的硬化的反应的硬化剂。

    Modification of lung region flow dynamics using flow control devices implanted in bronchial wall channels
    8.
    发明申请
    Modification of lung region flow dynamics using flow control devices implanted in bronchial wall channels 审中-公开
    使用植入支气管壁通道的流量控制装置修改肺区流动动力学

    公开(公告)号：US20050066974A1

    公开(公告)日：2005-03-31

    申请号：US10448153

    申请日：2003-05-28

    申请人： Antony Fields ,  Michael Hendricksen ,  Ronald Hundertmark

    发明人： Antony Fields ,  Michael Hendricksen ,  Ronald Hundertmark

    IPC分类号： A61F2/04 ,  A61F2/06 ,  A61F2/24 ,  A62B9/06 ,  A61M16/00

    CPC分类号： A61F2/2412 ,  A61F2/04 ,  A61F2/06 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/91 ,  A61F2002/043

    摘要： A desired fluid flow dynamic to a lung region can be achieved by deploying various combinations of flow control devices and bronchial isolation devices in one or more bronchial passageways that communicate with the lung region. The flow control devices are implanted in channels that are formed in the walls of bronchial passageways of the lung. The flow control devices regulate fluid flow through the channels. The bronchial isolation devices are implanted in lumens of bronchial passageways that communicate with the lung region in order to regulate fluid flow to and from the lung region through the bronchial passageways.

    摘要翻译： 可以通过在与肺部区域连通的一个或多个支气管通道中布置流量控制装置和支气管隔离装置的各种组合来实现动态到肺部区域的期望流体流动。 将流量控制装置植入形成在肺的支气管通道的壁中的通道中。 流量控制装置调节通过通道的流体流动。 支气管隔离装置被植入到与肺部区域连通的支气管通道的内腔中，以调节通过支气管通道的流入和流出肺部区域的流体。

    Implanted bronchial isolation device delivery devices and methods
    10.
    发明申请
    Implanted bronchial isolation device delivery devices and methods 审中-公开
    植入式支气管隔离装置及方法

    公开(公告)号：US20060030863A1

    公开(公告)日：2006-02-09

    申请号：US11186293

    申请日：2005-07-20

    申请人： Antony Fields ,  John McCutcheon ,  Alan Rapacki

    发明人： Antony Fields ,  John McCutcheon ,  Alan Rapacki

    IPC分类号： A61F11/00

    CPC分类号： A61B1/2676 ,  A61B1/0058 ,  A61B17/12104 ,  A61B2017/00292 ,  A61B2017/1205 ,  A61F2002/043

    摘要： Disclosed is a delivery system for insertion into a lung. The delivery system includes an elongate endoscope having a proximal end and a distal end and defining an internal lumen. The endoscope is configured to articulate in one or more directions. The system further includes a catheter that includes an elongate shaft sized to be inserted through the internal lumen of the endoscope. The catheter has a shape that aids in the articulation of the distal end of the endoscope when the catheter is positioned inside the endoscope.

    摘要翻译： 公开了用于插入肺的递送系统。 输送系统包括具有近端和远端并限定内腔的细长内窥镜。 内窥镜构造成在一个或多个方向上铰接。 该系统还包括导管，其包括细长轴，该细长轴的尺寸被插入穿过内窥镜的内腔。 当导管位于内窥镜内部时，导管具有帮助内窥镜的远端铰接的形状。