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    PREVENTION AND TREATMENT OF ITCH WITH CYSTEINE PROTEASE INHIBITION
    1.
    发明申请
    PREVENTION AND TREATMENT OF ITCH WITH CYSTEINE PROTEASE INHIBITION 有权
    使用CYSTEINE PROTEASE抑制剂预防和治疗ITCH

    公开(公告)号：US20110184016A1

    公开(公告)日：2011-07-28

    申请号：US13061188

    申请日：2009-08-28

    申请人： Ethan Lerner ,  Vemuri B. Reddy

    发明人： Ethan Lerner ,  Vemuri B. Reddy

    IPC分类号： A61K31/438 ,  A61P17/04

    CPC分类号： A61K31/00 ,  A61K31/437

    摘要： Embodiments of the invention relates to methods of preventing itch in a subject using a therapeutically effective amount of a cysteine protease inhibitor. The itch is not associated with psoriasis and atopic dermatitis. The itch is also a non-histamine mediated itch. The inhibitor are directed to the cathepsin selected from the group consisting of cathepsin B, C, F, J, K, H, L, P, Q, S, W, X, V, and Z.

    摘要翻译： 本发明的实施方案涉及使用治疗有效量的半胱氨酸蛋白酶抑制剂预防受试者的瘙痒的方法。 瘙痒与牛皮癣和特应性皮炎无关。 瘙痒也是非组胺介导的瘙痒。 抑制剂指向组织蛋白酶B，C，F，J，K，H，L，P，Q，S，W，X，V和Z组成的组织蛋白酶。

    Methods useful for controlling fluid loss during sand control operations
    5.
    发明申请
    Methods useful for controlling fluid loss during sand control operations 有权
    防砂控制操作中控制流体损失的方法

    公开(公告)号：US20050284632A1

    公开(公告)日：2005-12-29

    申请号：US10881198

    申请日：2004-06-29

    申请人： Eldon Dalrymple ,  Larny Eoff ,  B. Reddy

    发明人： Eldon Dalrymple ,  Larny Eoff ,  B. Reddy

    IPC分类号： C09K8/508 ,  C09K8/514 ,  C09K8/575 ,  E21B43/04

    CPC分类号： C09K8/5751 ,  C09K8/5083 ,  C09K8/5086 ,  C09K8/514

    摘要： The present invention relates to methods useful during sand control operations and, more particularly, to using water-soluble relative permeability modifiers that are useful for controlling fluid loss during sand control operations. In one embodiment, the present invention provides a method of providing fluid loss control during sand control operations comprising introducing a fluid that comprises a water-soluble relative permeability modifier into a well bore; and stabilizing unconsolidated formation particulates in a section of a subterranean formation penetrated by the well bore. In other embodiments, the present invention provides methods of providing fluid loss control during sand control operations and methods of reducing fluid loss from carrier fluids used in sand control operations.

    摘要翻译： 本发明涉及在砂控制操作期间有用的方法，更具体地说，涉及使用水控相对渗透性改进剂，其可用于控制防砂操作期间的流体损失。 在一个实施方案中，本发明提供了一种在砂控制操作期间提供流体损失控制的方法，包括将包含水溶性相对渗透性改性剂的流体引入井眼中; 并且在井眼穿透的地层的一部分中稳定未固结的地层颗粒。 在其他实施例中，本发明提供了在防砂控制操作期间提供流体损失控制的方法以及减少在砂控制操作中使用的载体流体的流体损失的方法。

    Methods and compositions for use with spacer fluids used in subterranean well bores
    7.
    发明申请
    Methods and compositions for use with spacer fluids used in subterranean well bores 有权
    用于地下井孔中的间隔液的方法和组合物

    公开(公告)号：US20050230116A1

    公开(公告)日：2005-10-20

    申请号：US10893210

    申请日：2004-07-16

    申请人： Larry Eoff ,  B. Reddy ,  Eldon Dalrymple

    发明人： Larry Eoff ,  B. Reddy ,  Eldon Dalrymple

    IPC分类号： C09K8/40 ,  E21B43/16

    CPC分类号： C09K8/40 ,  Y10S507/928

    摘要： The present invention relates to spacer fluids used in subterranean operations and, more particularly, to spacer fluids that comprise water-soluble relative permeability modifiers and methods of using the spacer fluids in subterranean operations. In one embodiment, the present invention provides a method of displacing a first fluid from a well bore that comprises introducing the first fluid into the well bore; and displacing the first fluid with a spacer fluid, the spacer fluid comprising water, and a water-soluble relative permeability modifier comprising a hydrophobically modified polymer or a hydrophilically modified polymer. In another embodiment, the present invention provides a spacer fluid that comprises water, and a water-soluble relative permeability modifier comprising a hydrophobically modified polymer or a hydrophilically modified polymer.

    摘要翻译： 本发明涉及在地下作业中使用的间隔液，更具体地说，涉及包含水溶性相对渗透性改性剂的隔离液和在地下操作中使用间隔液的方法。 在一个实施例中，本发明提供了一种从井眼移位第一流体的方法，其包括将第一流体引入井眼中; 并且用间隔液移动第一流体，间隔液包含水，以及包含疏水改性聚合物或亲水改性聚合物的水溶性相对渗透性改性剂。 在另一个实施方案中，本发明提供了包含水的间隔液，以及包含疏水改性聚合物或亲水改性聚合物的水溶性相对渗透性改性剂。

    Sealant compositions comprising colloidally stabilized latex and methods of using the same
    8.
    发明申请
    Sealant compositions comprising colloidally stabilized latex and methods of using the same 有权
    包含胶体稳定胶乳的密封剂组合物及其使用方法

    公开(公告)号：US20050230112A1

    公开(公告)日：2005-10-20

    申请号：US10827022

    申请日：2004-04-19

    申请人： B. Reddy ,  Anthony Palmer

    发明人： B. Reddy ,  Anthony Palmer

    IPC分类号： C04B28/02 ,  C09K8/467 ,  C09K8/506 ,  C09K8/508 ,  C09K8/514 ,  E21B33/13

    CPC分类号： C09K8/506 ,  C09K8/5083 ,  C09K8/5086 ,  C09K8/514

    摘要： Sealant compositions comprising a colloidally stabilized latex and methods of using the same to service a wellbore are provided. The sealant compositions may include: an aliphatic conjugated diene monomer; an additional monomer comprising a non-aromatic unsaturated mono- or di-carboxylic ester monomer, an aromatic unsaturated monomer, a nitrogen-containing monomer, or combinations thereof; and a protective colloid. The foregoing sealant composition may be displaced into the wellbore to isolate the subterranean formation from a portion of the wellbore, to support a conduit in the wellbore, to plug a void or crack in the conduit, to plug a void or crack in a cement sheath disposed in an annulus of the wellbore, to plug an opening between the cement sheath and the conduit, or combinations thereof. The colloidally stabilized latex remains substantially stable when exposed to salt, which may be present in the wellbore and/or in the sealant composition itself.

    摘要翻译： 提供了包含胶体稳定的胶乳的密封剂组合物和使用该密封剂组合物来维修井筒的方法。 密封剂组合物可包括：脂族共轭二烯单体; 包含非芳族不饱和单羧酸酯单体或二羧酸酯单体，芳族不饱和单体，含氮单体或其组合的另外的单体; 和保护胶体。 上述密封剂组合物可以移入井眼中以将地层与井筒的一部分隔离，以支撑井眼中的导管，以堵塞管道中的空隙或裂缝，以堵塞水泥套管中的空隙或裂缝 设置在井眼的环形空间中，以堵塞水泥护套和导管之间的开口，或其组合。 当暴露于盐时，胶体稳定的胶乳保持基本上稳定，盐可存在于井筒和/或密封剂组合物本身中。

    Well bore servicing fluids comprising thermally activated viscosification compounds and methods of using the same
    9.
    发明申请
    Well bore servicing fluids comprising thermally activated viscosification compounds and methods of using the same 有权
    包含热活化增粘化合物的井眼维修流体及其使用方法

    公开(公告)号：US20050178546A1

    公开(公告)日：2005-08-18

    申请号：US10780314

    申请日：2004-02-17

    申请人： B. Reddy ,  Frank Zamora ,  Ronney Koch ,  Joe Sandy ,  Ian Robb

    发明人： B. Reddy ,  Frank Zamora ,  Ronney Koch ,  Joe Sandy ,  Ian Robb

    IPC分类号： C09K8/035 ,  C09K8/68 ,  C09K8/70 ,  E21B43/04

    CPC分类号： C09K8/035 ,  C09K8/68 ,  C09K8/685 ,  C09K8/706

    摘要： Well bore servicing fluids are provided that include a thermally activated viscosification compound. Further, methods of servicing a well bore are provided that include displacing such a servicing fluid into the well bore, wherein a viscosity of the servicing fluid increases as it passes down the well bore due to its temperature increasing. Thus, the viscosity of the servicing fluid is effective to suspend solids therein when the servicing fluid is in the well bore. The servicing fluid may be, for example, a cement slurry, a drilling fluid, a gravel packing fluid, a fracturing fluid, a completion fluid, or a work-over fluid. In an embodiment, the thermally activated viscosification compound includes at least one water-soluble hydrophobically modified polymer comprising a hydrophobic substituent having from about 1 to about 22 carbon atoms.

    摘要翻译： 提供井眼维修流体，其包括热活化增稠化合物。 此外，提供了维修井眼的方法，其包括使这种维修流体移动到井眼中，其中当维修流体由于其温度升高而向下通过井眼时，维修流体的粘度增加。 因此，当维修流体在井眼中时，维修流体的粘度有效地将固体悬浮在其中。 维修流体可以是例如水泥浆，钻井液，砾石填充流体，压裂流体，完井流体或修补流体。 在一个实施方案中，热活化的增粘化合物包括至少一种包含具有约1至约22个碳原子的疏水取代基的水溶性疏水改性聚合物。

    Method of and apparatus for displaying and analyzing a physiological signal
    10.
    发明授权
    Method of and apparatus for displaying and analyzing a physiological signal 失效
    用于显示和分析生理信号的方法和装置

    公开(公告)号：US06920350B2

    公开(公告)日：2005-07-19

    申请号：US09922627

    申请日：2001-08-06

    申请人： Joel Q. Xue ,  Shankara B. Reddy

    发明人： Joel Q. Xue ,  Shankara B. Reddy

    IPC分类号： A61B5/044

    CPC分类号： A61B5/044 ,  A61B5/7264

    摘要： A method of displaying a representation of a physiological signal produced by a patient. The method includes the acts of obtaining a portion of at least one physiological signal acquired from the patient, determining an area to display, and constructing a virtual image representing at least a portion of the patient. The virtual image including (M) polygonal areas. The method further includes transforming the obtained signal to a plurality of values, assigning each value to one of the (M) polygonal areas, assigning a visual characteristic to each polygonal area based in part on the assigned values, and displaying at least a portion of the virtual image including the assigned visual characteristics. The invention further provides a method of optimal feature selection for the classification of the physiological signals produced by a patient.

    摘要翻译： 一种显示患者产生的生理信号的表示的方法。 该方法包括获得从患者获得的至少一个生理信号的一部分的动作，确定要显示的区域，以及构建表示患者的至少一部分的虚拟图像。 虚拟图像包括（M）多边形区域。 该方法还包括将获得的信号变换为多个值，将每个值分配给（M）个多边形区域中的一个，部分地基于分配值为每个多边形区域分配视觉特征，并且显示至少一部分 虚拟图像包括分配的视觉特征。 本发明还提供了一种用于对由患者产生的生理信号进行分类的最佳特征选择的方法。