公开(公告)号：US20070197842A1

公开(公告)日：2007-08-23

申请号：US11619592

申请日：2007-01-03

Applicant: Sudip Mukhopadhyay ,  Hsueh Tung ,  Barbara Light ,  Steven Phillips ,  Jing Ma ,  Cheryl Bortz ,  Michael Van Der Puy ,  Daniel Merkel ,  Rajesh Dubey

Inventor： Sudip Mukhopadhyay ,  Hsueh Tung ,  Barbara Light ,  Steven Phillips ,  Jing Ma ,  Cheryl Bortz ,  Michael Van Der Puy ,  Daniel Merkel ,  Rajesh Dubey

IPC: C07C21/18 ,  C07C17/25

CPC classification number: C07C17/25 ,  C07C17/00 ,  C07C17/04 ,  C07C17/087 ,  C07C17/10 ,  C07C17/20 ,  C07C17/204 ,  C07C17/206 ,  C07C17/21 ,  C07C17/26 ,  C07C17/269 ,  C07C17/272 ,  C07C17/278 ,  C07C21/18 ,  C07C19/01 ,  C07C19/10 ,  C07C19/08 ,  C07C21/073 ,  C07C21/04

Abstract: Disclosed are processes for the production of fluorinated olefins, preferably adapted to commercialization of CF3CF═CH2 (1234yf). Three steps may be used in preferred embodiments in which a feedstock such as CCl2═CClCH2Cl (which may be purchased or synthesized from 1,2,3-trichloropropane) is fluorinated (preferably with HF in gas-phase in the presence of a catalyst) to synthesize a compound such as CF3CCl═CH2, preferably in a 80-96% selectivity. The CF3CCl═CH2 is preferably converted to CF3CFClCH3 (244-isomer) using a SbCl5 as the catalyst which is then transformed selectively to 1234yf, preferably in a gas-phase catalytic reaction using activated carbon as the catalyst. For the first step, a mixture of Cr2O3 and FeCl3/C is preferably used as the catalyst to achieve high selectivity to CF3CCl═CH2 (96%). In the second step, SbCl5/C is preferably used as the selective catalyst for transforming 1233xf to 244-isomer, CF3CFClCH3. The intermediates are preferably isolated and purified by distillation and used in the next step without further purification, preferably to a purity level of greater than about 95%.

Abstract translation: 公开了用于生产氟化烯烃的方法，优选适于CF 3 CH 2 CH 2（1234yf）的商业化。 在优选实施方案中可以使用三个步骤，其中原料如CCl 2 -CClCH 2 Cl（其可以从1,2,3-三氯丙烷购买或合成） 被氟化（优选在催化剂存在下在气相中用HF）合成化合物如CF 3 CCl-CH 2，优选在80-96 ％选择性。 CF 3 CCl-CH 2 2优选使用以下化合物转化为CF 3 CFClCH 3（244-异构体） SbCl 5作为催化剂，然后将其选择性地转化为1234yf，优选在使用活性炭作为催化剂的气相催化反应中进行。 对于第一步，优选使用Cr 2 O 3 O 3和FeCl 3 / C的混合物作为催化剂以实现对CF的高选择性 3 CCl-CH 2（96％）。 在第二步中，优选使用SbCl 5 / C作为将1233xf转化为244-异构体CF 3 CFClCH 3的选择性催化剂。 中间体优选通过蒸馏分离和纯化，并用于下一步骤而不进一步纯化，优选纯度高于约95％。

公开(公告)号：US20070197841A1

公开(公告)日：2007-08-23

申请号：US11619589

申请日：2007-01-03

Applicant: Sudip Mukhopadhyay ,  Hsueh Tung ,  Michael Van Der Puy ,  Daniel Merkel ,  Jing Ji Ma ,  Cheryl Bortz ,  Barbara Light ,  Steven Phillips ,  Kim Fleming ,  Susan Ferguson

Inventor： Sudip Mukhopadhyay ,  Hsueh Tung ,  Michael Van Der Puy ,  Daniel Merkel ,  Jing Ji Ma ,  Cheryl Bortz ,  Barbara Light ,  Steven Phillips ,  Kim Fleming ,  Susan Ferguson

IPC: C07C21/18 ,  C07C17/25

CPC classification number: C07C17/23 ,  C07C17/087 ,  C07C17/10 ,  C07C17/206 ,  C07C17/21 ,  C07C17/25 ,  C07C19/08 ,  C07C19/10 ,  C07C21/18

Abstract: Disclosed is a process for producing fluorinated organic compounds, including hydrofluoropropenes, which preferably comprises converting at least one compound of Formula (I): C(X)3CF2C(X)3  (I) to at least one compound of Formula (II) CF3CF═CHZ  (II) where each X and Z is independently H, F, Cl, I or Br, said process preferably not including any substantial amount of oxygen-containing catalyst in certain embodiments. Preferably Z is H.

Abstract translation: 公开了一种生产含氟有机化合物的方法，包括氢氟丙烯，其优选包括转化至少一种式（I）的化合物：<？在线式描述=“在线式”末端=“铅”→> （X）3 C（X）3（I）<？in-line-formula description =“In-line Formulas” 结束=“尾”→至少一种式（II）的化合物<？在线公式描述=“在线公式”end =“lead”？> CF 3 CF- CHZ（II）<？in-line-formula description =“In-line Formulas”end =“tail”？>其中每个X和Z独立地为H，F，Cl，I或Br，所述方法优选不包括任何实质 在某些实施方案中含氧催化剂的量。 Z优选为

公开(公告)号：US20070112228A1

公开(公告)日：2007-05-17

申请号：US11592415

申请日：2006-11-03

Applicant: Sudip Mukhopadhyay ,  Haridasan Nair ,  Hsueh Tung ,  Michael Van Der Puy ,  Daniel Merkel ,  Rajesh Dubey ,  Jing Ji Ma ,  Barbara Light ,  Kim Fleming ,  Cheryl Bortz ,  Richard Udy

Inventor： Sudip Mukhopadhyay ,  Haridasan Nair ,  Hsueh Tung ,  Michael Van Der Puy ,  Daniel Merkel ,  Rajesh Dubey ,  Jing Ji Ma ,  Barbara Light ,  Kim Fleming ,  Cheryl Bortz ,  Richard Udy

IPC: C07C17/093

CPC classification number: C07C17/00 ,  C07C17/02 ,  C07C17/04 ,  C07C17/10 ,  C07C21/18 ,  C07C19/08 ,  C07C19/10

Abstract: A method for preparing fluorinated organic compounds comprising contacting hydrogen fluoride with at least one compound of formula I: CX3CXYCH3  Iwhere each X is independently Cl, I or Br, and each Y is independently H or F, said contacting step being carried out under conditions effective to produce a compound of formula II CF3CZCH2  IIwhere Z is Cl, I, Br, or F.

Abstract translation: 一种制备氟化有机化合物的方法，包括使氟化氢与至少一种式I化合物接触：<？in-line-formula description =“In-Line Formulas”end =“lead”→> 3 其中每个X独立地为Cl，I或Br，并且每个Y独立地为H，其中每个X独立地为H， 或F，所述接触步骤在有效产生式II化合物的条件下进行。＆lt;线内公式描述=“在线配方”末端=“铅”→CF 3 CZCH II II <？in-line-formula description =“In-line Formulas”end =“tail”？>其中Z是Cl，I，Br或F.