System for Determining the Displacement of a Movable Member
    4.
    发明申请
    System for Determining the Displacement of a Movable Member 失效
    确定移动构件位移的系统

    公开(公告)号:US20070256507A1

    公开(公告)日:2007-11-08

    申请号:US11661481

    申请日:2005-08-26

    申请人: Barry Morgan

    发明人: Barry Morgan

    IPC分类号: G01L1/00 G01L3/00

    摘要: A means for simultaneous determination of the radial and angular vectors of rotary motion of a body relative to a single reference axis, by measurement of the common aid differential states of three position detectors and, together with an axial position detector, thus to allow the measurable modulation of magnetic devices such as to provide measurable vector forces to support that body against the vector effects of any external forces that tend to change its position relative to the reference axis, in the absence of any contact between the rotor and the combined system of sensors and magnetic devices. Measurement of the vector forces applied to the suspended b>dC and its resultant vector displacements, provides the functional basis of a device suitable for measuring the effects of mechanical interaction between that body and any spatially constrained sample material in contact with the b>dC, with respect to the applied vector stresses and resultant vector strains that exist as a result of any shearing or grinding abrasion or indentation deformation or cutting action applied by the rotor to that material during a measured time period. The basic device being consistent with the functions of a rotary viscometer or rheometer or appropriate for use in evaluating the action of a drilling or milling cutter, even when the sample material and the b>dC are confined within a chamber subjected to low or high internal pressure with respect to the external environment. Such confinement also avoids volatile loss of constituents from the sample material and any environmental hazard arising from such loss.

    摘要翻译: 一种用于通过测量三个位置检测器的共同帮助差分状态并与轴向位置检测器一起同时确定主体相对于单个参考轴线的旋转运动的径向和角度向量的装置,从而允许可测量 磁性装置的调制,例如在转子和传感器的组合系统之间没有任何接触的情况下,提供可测量的矢量力以支持该体抵抗倾向于改变其相对于参考轴线的位置的任何外力的矢量效应 和磁性装置。 施加到悬浮的b> dC的向量力的测量及其合成的向量位移提供了适合于测量该体与任何与b> dC接触的任何空间受限的样品材料之间的机械相互作用的影响的装置的功能基础, 相对于在测量的时间段期间由转子施加到该材料上的任何剪切或研磨磨损或压痕变形或切割动作而存在的施加矢量应力和合成矢量应变。 基本装置与旋转式粘度计或流变仪的功能一致,或适用于评估钻孔或铣刀的作用,即使样品材料和b> dC被限制在经受低或高内部的室内 相对于外部环境的压力。 这种限制也避免了样品中成分的挥发性损失以及由此造成的任何环境危害。

    Prenyl transferase inhibitors
    7.
    发明申请
    Prenyl transferase inhibitors 失效
    丙烯酰转移酶抑制剂

    公开(公告)号:US20060142275A1

    公开(公告)日:2006-06-29

    申请号:US11353518

    申请日:2006-02-14

    IPC分类号: A61K31/551 C07D487/04

    CPC分类号: C07D487/04 C07D513/14

    摘要: A family of imidazole compounds useful for inhibiting the activity of prenyl transferases. The compounds are covered by the following formula: wherein X is (CHR11)n3(CH2)n4Z(CH2)n5 where Z is O, N(R12), S, or a bond; Y is CO, CH2, CS, or a bond; R1 is or N(R24R25); and the remaining substituents are as defined in the disclosure.

    摘要翻译: 用于抑制异戊烯基转移酶活性的咪唑化合物家族。 化合物被下式所覆盖:其中X是(CHR 11)n 3(CH 2)n 4 Z(CH 2)n N 5其中Z是O,N(R 12),S或键; Y是CO,CH 2,CS或键; R 1是或N(R 24,R 25); 并且其余的取代基如本公开中所定义。