摘要:
A system and method of designing a fiber optic network for a plurality of premises in a geographic area that has existing infrastructure is described. They include electronically receiving fiber optic network design inputs that include data indicative of a plurality of nodes in the fiber optic network and data indicative of arcs extending between said nodes in the fiber optic network based on allocated bandwidth for said premises in the geographic area, electronically receiving existing infrastructure design inputs comprising data indicative of said existing infrastructure that can be used as geographic locations for said nodes and said arcs in the fiber optic network, electronically generating design outputs by optimizing geographic locations of said nodes and said arcs in the fiber optic network using said fiber optic network design inputs and said existing infrastructure inputs, and electronically outputting the design outputs.
摘要:
A method for generating a transportation plan. A set of transportation requests are identified. An initial transportation plan having a set of vehicle routes, a set of vehicle schedules, and a set of crew schedules that satisfy the set of transportation requests is created. A set of vehicle routes, a set of vehicle schedules, and a set of crew schedules are simultaneously modified repeatedly using a policy to generate a new transportation plan until an objective is met.
摘要:
The inventors herein describe methods for the production of a functional human, animal, plant or microbe protein arrays and methods to assay for interactions between the proteins on the array with molecules of interest, for example, using such arrays to determine the in vitro metabolite profile of any drug. Such protein arrays can be used, for example, to assay, in a parallel fashion, the protein products of DNA sequences encoding drug metabolizing enzymes (DMES) to obtain a toxicology profile. Also described herein is a novel DME expression and purification strategy using detergents and not requiring an ultra-centrifugation step.
摘要:
A method for generating a transportation plan. A set of transportation requests are identified. An initial transportation plan having a set of vehicle routes, a set of vehicle schedules, and a set of crew schedules that satisfy the set of transportation requests is created. A set of vehicle routes, a set of vehicle schedules, and a set of crew schedules are simultaneously modified repeatedly using a policy to generate a new transportation plan until an objective is met.
摘要:
An acoustic system kit for a vehicle speaker and associated methods of installation and manufacture are disclosed. A drum of open-cell foam, preferably several inches thick, having a peel-and-stick pressure-sensitive adhesive backing is cut with two concentric circles to create an outer ring, and inner ring, and a core. The parts are sized to correspond in diameter, respectively, to the front edge, rear edge, and back disc of a particular size of speaker. The inner ring is cut circumferentially to reduce its height to a thin strip relative to the outer ring and drum. Using the pressure-sensitive adhesive, the core is affixed to the inside wall of vehicle door directly behind the door's speaker mount, the inner ring is affixed to the rear edge of a speaker to be installed, and the outer ring is affixed to front edge of the speaker. The speaker is then installed on its mount.
摘要:
A counter comprises a body housing a set of discs which are freely rotatable on a sleeve and which have numerals on their peripheries. A series of drive plates are keyed to the sleeve and interleaved with the discs. At one end of the set of discs a spring-loaded collar also keyed to the sleeve urges the drive plates and discs into frictional engagement. The sleeve is rotatable with a reset wheel while the collar is driven by a star counting wheel through an orbital drive arrangement. The orbital drive arrangement may include a further collar having outwardly directed projections thereon which engage an abutment carried by a resilient arm, the abutment and projections restraining the further collar against rotation during counting. Each disc has a set of first abutments and a second abutment on its periphery. Spring blades engage the peripheries of the discs and have respective resilient stops thereon to engage the first abutments so as to oppose movement of the discs in a counting direction but to permit movement thereof in a reset direction. All the discs but one end disc are each provided with a resilient detent which is positioned in the path of movement of the second abutment. Each resilient detent is carried by the spring blade which mounts the resilient stop associated with an adjacent disc.
摘要:
A system and method of designing a fibre optic network for a plurality of premises in a geographic area that has existing infrastructure is described. They include electronically receiving fibre optic network design inputs that include data indicative of a plurality of nodes in the fibre optic network and data indicative of arcs extending between said nodes in the fibre optic network based on allocated bandwidth for said premises in the geographic area, electronically receiving existing infrastructure design inputs comprising data indicative of said existing infrastructure that can be used as geographic locations for said nodes and said arcs in the fibre optic network, electronically generating design outputs by optimising geographic locations of said nodes and said arcs in the fibre optic network using said fibre optic network design inputs and said existing infrastructure inputs, and electronically outputting the design outputs.
摘要:
Compounds and related methods for synthesis, and the use of compounds and combination therapies for the treatment of cancer and modulation of apoptosis in cells are disclosed. The generation of synthetic combinatorial libraries and the evaluation of library member compounds regarding induction of apoptosis selectively in cancer cells are disclosed. Compounds, methods of making the compounds, and therapeutic methods with application against breast cancer cells, melanoma cancer cells, colon cancer cells, and other cancer cells are described.