公开(公告)号：US20060141080A1

公开(公告)日：2006-06-29

申请号：US11360653

申请日：2006-02-23

Applicant: Ghulam Qazi ,  Kasturi Bedi ,  Rakesh Johri ,  Manoj Tikoo ,  Ashok Tikoo ,  Subhash Sharma ,  Sheikh Absullah ,  Om Suri ,  Bishan Gupta ,  Krishan Suri ,  Naresh Satti ,  Ravi Khajuria ,  Surjit Singh ,  Anamika Khajuria ,  Bal Kapahi

Inventor： Ghulam Qazi ,  Kasturi Bedi ,  Rakesh Johri ,  Manoj Tikoo ,  Ashok Tikoo ,  Subhash Sharma ,  Sheikh Absullah ,  Om Suri ,  Bishan Gupta ,  Krishan Suri ,  Naresh Satti ,  Ravi Khajuria ,  Surjit Singh ,  Anamika Khajuria ,  Bal Kapahi

IPC: A61K36/23

CPC classification number: A61K45/06 ,  A23L33/105 ,  A23L33/15 ,  A23L33/16 ,  A23L33/175 ,  A61K31/43 ,  A61K31/4453 ,  A61K31/4709 ,  A61K31/496 ,  A61K31/545 ,  A61K31/704 ,  A61K31/7048 ,  A61K33/04 ,  A61K36/185 ,  A61K36/19 ,  A61K36/23 ,  A61K36/28 ,  A61K36/47 ,  A61K36/59 ,  A61K36/67 ,  A61K36/75 ,  A61K36/80 ,  A61K36/81 ,  A61K36/8965 ,  A61K2300/00

Abstract: The present invention relates to a bioenhancing/bioavailability-facilitating composition comprising: an effective amount of an extract and/or at least one bioactive fraction from Cuminum cyminum; one or more additive selected from drugs, nutrients, vitamins, nutraceuticals, herbal drugs/products, micro nutrients, antioxidants along with pharmaceuticaly acceptable additives/excipient, and optionally, an effective amount of piperine or extract/fraction of piper nigrum or piper longum; and a process for the preparation of such extracts and active fractions from plant Cuminum cyminum.

Abstract translation: 本发明涉及生物增强/生物利用度促进组合物，其包含：有效量的来自孜然的提取物和/或至少一种生物活性级分; 一种或多种选自药物，营养素，维生素，营养品，草药/产品，微量营养素，抗氧化剂以及药用可接受的添加剂/赋形剂的添加剂，以及任选的有效量的胡椒碱或胡椒或胡椒的提取物/级分; 以及从植物孜然中制备这些提取物和活性级分的方法。

公开(公告)号：US20070020347A1

公开(公告)日：2007-01-25

申请号：US11478228

申请日：2006-06-29

Applicant: Ghulam Qazi ,  Kasturi Bedi ,  Rakesh Johri ,  Manoj Tikoo ,  Ashok Tikoo ,  Subhash Sharma ,  Tasaduaq Abdullah ,  Om Suri ,  Bishan Gupta ,  Krishan Suri ,  Naresh Satti ,  Ravi Khajuria

Inventor： Ghulam Qazi ,  Kasturi Bedi ,  Rakesh Johri ,  Manoj Tikoo ,  Ashok Tikoo ,  Subhash Sharma ,  Tasaduaq Abdullah ,  Om Suri ,  Bishan Gupta ,  Krishan Suri ,  Naresh Satti ,  Ravi Khajuria

IPC: A61K36/906 ,  A61K36/18 ,  A61K31/7048 ,  A61K31/496 ,  A61K31/4709 ,  A61K31/545 ,  A61K31/43

CPC classification number: A61K31/7048 ,  A61K31/496 ,  A61K31/497 ,  A61K36/23 ,  A61K36/67 ,  A61K36/9068 ,  A61K2300/00

Abstract: The present invention relates to the use of extracts of Carum carvi as bioenhancers, either alone or in combination with piperine or Zinzeber officinale extract to improve the bioavailability of a wide variety of drugs.

Abstract translation: 本发明涉及Carum carvi提取物作为生物降解剂的用途，单独使用或与胡椒碱或锌盐提取物组合以提高各种药物的生物利用度。

公开(公告)号：US20050214390A1

公开(公告)日：2005-09-29

申请号：US10992141

申请日：2004-11-18

Applicant: Ghulam Qazi ,  Kasturi Bedi ,  Rakesh Johri ,  Manoj Tikoo ,  Ashok Tikoo ,  Subhas Sharma ,  Tasaduaq Abdullah ,  Om Suri ,  Bishan Gupta ,  Krishan Suri ,  Naresh Satti ,  Ravi Khajuria

Inventor： Ghulam Qazi ,  Kasturi Bedi ,  Rakesh Johri ,  Manoj Tikoo ,  Ashok Tikoo ,  Subhas Sharma ,  Tasaduaq Abdullah ,  Om Suri ,  Bishan Gupta ,  Krishan Suri ,  Naresh Satti ,  Ravi Khajuria

IPC: A61K31/496 ,  A61K31/497 ,  A61K31/7048 ,  A61K36/23 ,  A61K36/67 ,  A61K36/9068 ,  A61K35/78

CPC classification number: A61K31/7048 ,  A61K31/496 ,  A61K31/497 ,  A61K36/23 ,  A61K36/67 ,  A61K36/9068 ,  A61K2300/00

Abstract: The present invention relates to the use of extracts of Carum carvi as bioenhancers, either alone or in combination with piperine or Zinzeber officinale extract to improve the bioavailability of a wide variety of drugs.

Abstract translation: 本发明涉及Carum carvi提取物作为生物降解剂的用途，单独使用或与胡椒碱或锌盐提取物组合以提高各种药物的生物利用度。

公开(公告)号：US20060280817A1

公开(公告)日：2006-12-14

申请号：US11440790

申请日：2006-05-25

Applicant: Ajit Saxena ,  Bishan Gupta ,  Bal Kapahi ,  Shanmugavel Muthiah ,  Dilip Mondhe ,  Baleshwar ,  Ghulam Qazi ,  Vijay Kumar ,  Ganeshan Mathan

Inventor： Ajit Saxena ,  Bishan Gupta ,  Bal Kapahi ,  Shanmugavel Muthiah ,  Dilip Mondhe ,  Baleshwar ,  Ghulam Qazi ,  Vijay Kumar ,  Ganeshan Mathan

IPC: A61K36/48

CPC classification number: A61K36/48

Abstract: The present invention relates to anticancer activity against hepatocellular carcinoma of an extract and fraction isolated from flowers of Butea monosperma. Particularly, this invention relates to anticancer activity against hepatocellular carcinoma of a composition containing markered flavonoid glycosides such as butrin and isobutrin in the range of 2 to 9% by weight, isolated from the flowers of Butea monosperma by extracting the flowers with polar solvent like ethanol, methanol, aqueous ethanol or water, removing fatty non-polar constituents by triturating the extract with solvents such as ethylene chloride, methylene chloride, chloroform or ethyl acetate, suspending the residue in water, extracting with n-butanol and freeze drying the aqueous part.

Abstract translation: 本发明涉及一种提取物对肝细胞癌的抗癌活性和从白花单倍体花中分离的部分。 特别地，本发明涉及通过用极性溶剂如乙醇提取鲜花，从含有白芍的花中分离出含有2至9重量％的标记的类黄酮苷类的标记黄酮糖苷类化合物的抗癌活性 ，甲醇，乙醇水溶液或水中，通过用溶剂如氯化乙烯，二氯甲烷，氯仿或乙酸乙酯研磨提取物除去脂肪非极性组分，将残余物悬浮在水中，用正丁醇萃取并冷冻干燥含水部分 。

公开(公告)号：US20060257505A1

公开(公告)日：2006-11-16

申请号：US11360839

申请日：2006-02-23

Applicant: Ghulam Qazi ,  Kasturi Bedi ,  Rakesh Johri ,  Manoj Tikoo ,  Ashok Tikoo ,  Subhash Sharma ,  Tasaduaq Abdullah ,  Om Suri ,  Bishan Gupta ,  Krishan Suri ,  Naresh Satti ,  Ravi Khajuria

Inventor： Ghulam Qazi ,  Kasturi Bedi ,  Rakesh Johri ,  Manoj Tikoo ,  Ashok Tikoo ,  Subhash Sharma ,  Tasaduaq Abdullah ,  Om Suri ,  Bishan Gupta ,  Krishan Suri ,  Naresh Satti ,  Ravi Khajuria

IPC: A61K36/185 ,  A61K31/7048 ,  A61K31/496 ,  A61K31/4709 ,  A61K36/906 ,  A61K31/43 ,  A61K31/545

CPC classification number: A61K36/23 ,  A61K31/43 ,  A61K31/4709 ,  A61K31/496 ,  A61K31/545 ,  A61K31/7048 ,  A61K36/9068 ,  A61K2300/00

Abstract: The present invention relates to the use of extracts of Carum carvi as bioenhancers, either alone or in combination with piperine or Zinzeber officinale extract to improve the bioavailability of a wide variety of drugs.

Abstract translation: 本发明涉及Carum carvi提取物作为生物降解剂的用途，单独使用或与胡椒碱或锌盐提取物组合以提高各种药物的生物利用度。

公开(公告)号：US20050192251A1

公开(公告)日：2005-09-01

申请号：US11115823

申请日：2005-04-27

Applicant: Sunil Banerjee ,  Om Gupta ,  Subhash Taneja ,  Bishan Gupta ,  Vijay Sethi ,  Avtar Anand ,  Lila Manhas ,  Rajinder Gupta ,  Sarang Bani ,  Surjeet Singh ,  Neelam Sharma ,  Sukhdev Handa

Inventor： Sunil Banerjee ,  Om Gupta ,  Subhash Taneja ,  Bishan Gupta ,  Vijay Sethi ,  Avtar Anand ,  Lila Manhas ,  Rajinder Gupta ,  Sarang Bani ,  Surjeet Singh ,  Neelam Sharma ,  Sukhdev Handa

IPC: A61K31/736 ,  C08B37/00

CPC classification number: A61K31/736 ,  C08B37/006

Abstract: The present invention relates to a water-soluble bioactive fraction obtained from the gum resin exudate of Boswellia serrata and to a process for the preparation thereof. The present invention also relates to a process for the isolation of a water soluble bioactive fraction containing a mixture of potassium and calcium salts of polysaccharides composed of units of arabinose, galactose and D-glucuronic acid, having marked anti-inflammatory and anti-arthritic activities from the gum resin exudate of Boswellia serrata and to the use thereof in the treatment of arthritis in the form of a pharmaceutical composition containing the bioactive fraction.

Abstract translation: 本发明涉及由浆状乳杆菌的树胶渗出液获得的水溶性生物活性成分及其制备方法。 本发明还涉及一种分离含有由阿拉伯糖，半乳糖和D-葡萄糖醛酸单元组成的多糖的钾盐和钙盐混合物的水溶性生物活性级分的方法，具有明显的抗炎和抗关节炎活性 来自浆状乳杆菌的树胶渗出液，以及其用于治疗关节炎的用途，其为包含生物活性级分的药物组合物的形式。