公开(公告)号：US20060280817A1

公开(公告)日：2006-12-14

申请号：US11440790

申请日：2006-05-25

申请人： Ajit Saxena ,  Bishan Gupta ,  Bal Kapahi ,  Shanmugavel Muthiah ,  Dilip Mondhe ,  Baleshwar ,  Ghulam Qazi ,  Vijay Kumar ,  Ganeshan Mathan

发明人： Ajit Saxena ,  Bishan Gupta ,  Bal Kapahi ,  Shanmugavel Muthiah ,  Dilip Mondhe ,  Baleshwar ,  Ghulam Qazi ,  Vijay Kumar ,  Ganeshan Mathan

IPC分类号： A61K36/48

CPC分类号： A61K36/48

摘要： The present invention relates to anticancer activity against hepatocellular carcinoma of an extract and fraction isolated from flowers of Butea monosperma. Particularly, this invention relates to anticancer activity against hepatocellular carcinoma of a composition containing markered flavonoid glycosides such as butrin and isobutrin in the range of 2 to 9% by weight, isolated from the flowers of Butea monosperma by extracting the flowers with polar solvent like ethanol, methanol, aqueous ethanol or water, removing fatty non-polar constituents by triturating the extract with solvents such as ethylene chloride, methylene chloride, chloroform or ethyl acetate, suspending the residue in water, extracting with n-butanol and freeze drying the aqueous part.

摘要翻译： 本发明涉及一种提取物对肝细胞癌的抗癌活性和从白花单倍体花中分离的部分。 特别地，本发明涉及通过用极性溶剂如乙醇提取鲜花，从含有白芍的花中分离出含有2至9重量％的标记的类黄酮苷类的标记黄酮糖苷类化合物的抗癌活性 ，甲醇，乙醇水溶液或水中，通过用溶剂如氯化乙烯，二氯甲烷，氯仿或乙酸乙酯研磨提取物除去脂肪非极性组分，将残余物悬浮在水中，用正丁醇萃取并冷冻干燥含水部分 。

公开(公告)号：US20060121138A1

公开(公告)日：2006-06-08

申请号：US11271747

申请日：2005-11-14

申请人： Rakesh Johri ,  Sheikh Abdullah ,  Kuldeep Singh ,  Devinder Gupta ,  Bal Kapahi ,  Dilip Mondhe ,  Satinder Jain ,  Om Suri ,  Kasturi Bedi ,  Ghulam Qazi

发明人： Rakesh Johri ,  Sheikh Abdullah ,  Kuldeep Singh ,  Devinder Gupta ,  Bal Kapahi ,  Dilip Mondhe ,  Satinder Jain ,  Om Suri ,  Kasturi Bedi ,  Ghulam Qazi

IPC分类号： A61K36/185 ,  A61K31/4965 ,  A61K31/496 ,  A61K31/355

CPC分类号： A61K36/47 ,  A61K2300/00

摘要： The present invention relates to a composition useful for hepatocurative effect against CYP 450 bio-activation hepatotoxicity induced by drugs, said composition comprising an extract from Emblica officinalis and optionally pharmaceutically acceptable additives and method of treating drug induced hepatotoxicity.

摘要翻译： 本发明涉及一种可用于对由药物诱导的CYP 450生物活化肝毒性的肝脏作用的组合物，所述组合物包含来自Emblica officinalis的提取物和任选的药学上可接受的添加剂和治疗药物诱导的肝毒性的方法。

公开(公告)号：US20060141080A1

公开(公告)日：2006-06-29

申请号：US11360653

申请日：2006-02-23

申请人： Ghulam Qazi ,  Kasturi Bedi ,  Rakesh Johri ,  Manoj Tikoo ,  Ashok Tikoo ,  Subhash Sharma ,  Sheikh Absullah ,  Om Suri ,  Bishan Gupta ,  Krishan Suri ,  Naresh Satti ,  Ravi Khajuria ,  Surjit Singh ,  Anamika Khajuria ,  Bal Kapahi

发明人： Ghulam Qazi ,  Kasturi Bedi ,  Rakesh Johri ,  Manoj Tikoo ,  Ashok Tikoo ,  Subhash Sharma ,  Sheikh Absullah ,  Om Suri ,  Bishan Gupta ,  Krishan Suri ,  Naresh Satti ,  Ravi Khajuria ,  Surjit Singh ,  Anamika Khajuria ,  Bal Kapahi

IPC分类号： A61K36/23

CPC分类号： A61K45/06 ,  A23L33/105 ,  A23L33/15 ,  A23L33/16 ,  A23L33/175 ,  A61K31/43 ,  A61K31/4453 ,  A61K31/4709 ,  A61K31/496 ,  A61K31/545 ,  A61K31/704 ,  A61K31/7048 ,  A61K33/04 ,  A61K36/185 ,  A61K36/19 ,  A61K36/23 ,  A61K36/28 ,  A61K36/47 ,  A61K36/59 ,  A61K36/67 ,  A61K36/75 ,  A61K36/80 ,  A61K36/81 ,  A61K36/8965 ,  A61K2300/00

摘要： The present invention relates to a bioenhancing/bioavailability-facilitating composition comprising: an effective amount of an extract and/or at least one bioactive fraction from Cuminum cyminum; one or more additive selected from drugs, nutrients, vitamins, nutraceuticals, herbal drugs/products, micro nutrients, antioxidants along with pharmaceuticaly acceptable additives/excipient, and optionally, an effective amount of piperine or extract/fraction of piper nigrum or piper longum; and a process for the preparation of such extracts and active fractions from plant Cuminum cyminum.

摘要翻译： 本发明涉及生物增强/生物利用度促进组合物，其包含：有效量的来自孜然的提取物和/或至少一种生物活性级分; 一种或多种选自药物，营养素，维生素，营养品，草药/产品，微量营养素，抗氧化剂以及药用可接受的添加剂/赋形剂的添加剂，以及任选的有效量的胡椒碱或胡椒或胡椒的提取物/级分; 以及从植物孜然中制备这些提取物和活性级分的方法。