公开(公告)号：US09662347B2

公开(公告)日：2017-05-30

申请号：US13697332

申请日：2011-04-28

申请人： Bong Hee Lee ,  Kyung Hee Byun

发明人： Bong Hee Lee ,  Kyung Hee Byun

IPC分类号： A61K31/7076 ,  A61K31/13 ,  A61K31/197 ,  A61K31/221 ,  A61K31/4168 ,  A61K31/196 ,  A61K31/225 ,  A61K31/473 ,  A61K31/4745 ,  A61K31/519 ,  A61K31/545 ,  A61K31/546 ,  A61K31/56 ,  A61K31/663 ,  A61K31/137 ,  A61K31/165 ,  A61K31/40 ,  A61K31/445 ,  A61K31/4525 ,  A61K31/713

CPC分类号： A61K31/7076 ,  A61K31/13 ,  A61K31/137 ,  A61K31/165 ,  A61K31/196 ,  A61K31/197 ,  A61K31/221 ,  A61K31/225 ,  A61K31/40 ,  A61K31/4168 ,  A61K31/445 ,  A61K31/4525 ,  A61K31/473 ,  A61K31/4745 ,  A61K31/519 ,  A61K31/545 ,  A61K31/546 ,  A61K31/56 ,  A61K31/663 ,  A61K31/713

摘要： The present invention relates to a method for inhibiting the induction of cell death by inhibiting the synthesis or secretion of AGE-albumin in cells of the mononuclear phagocyte system, to an AGE-albumin synthesis inhibitor, and to a pharmaceutical composition comprising the AGE-albumin synthesis inhibitor for preventing or treating degenerative disease and autoimmune disease. The AGE-albumin of the present invention is synthesized and secreted in human microglia or human macrophages in an Alzheimer's model, stroke model, Parkinson's disease model and rheumatoid arthritis model. The AGE-albumin synthesis and secretion are caused by oxidative stress. The expression of RAGE increases in first-order human neurons or cartilage cells to which AGE-albumin is administered, whereupon a MAPK signaling pathway is activated and the expression of Bax increases to induce an increase in calcium in mitochondria, thus finally inducing cell death. Therefore, the AGE-albumin synthesis inhibitor of the present invention can be valuably used in the diagnosis or treatment of degenerative diseases or autoimmune diseases such as Alzheimer's disease, strokes, Parkinson's disease, amyotrophic lateral sclerosis, rheumatoid arthritis, diabetic retinopathy, AIDS, aging, pulmonary fibrosis, spinal cord injuries, etc.

公开(公告)号：US07831188B2

公开(公告)日：2010-11-09

申请号：US12105444

申请日：2008-04-18

申请人： Bong Hee Lee

发明人： Bong Hee Lee

IPC分类号： G03G15/20

CPC分类号： G03G15/2053 ,  G03G2215/2032

摘要： An image forming apparatus and a fusing unit thereof. The image forming apparatus includes a photosensitive body on which to form an electrostatic latent image, an exposure device to irradiate light to the photosensitive body to form the electrostatic latent image, a developer adhering device to adhere a developer to the photosensitive body on which the electrostatic latent image has been formed to form a visible image, a transfer device to transfer the visible image formed on the photosensitive body onto a printing medium, and a fusing unit to fuse the visible image transferred onto the printing medium to the printing medium. The fusing unit includes a press roller, a heating belt to closely contact the press roller to form a fusing nip to apply heat and pressure to the printing medium onto which the visible image has been transferred, first and second support rollers disposed apart from each other to circulatingly support the heating belt, and an elastic support device to elastically bias the first support roller and/or the second support roller in a direction away from each other to maintain a constant tension of the heating belt.

摘要翻译： 图像形成装置及其定影单元。 图像形成装置包括在其上形成静电潜像的感光体，将光照射到感光体以形成静电潜像的曝光装置，用于将显影剂粘附到静电的感光体上的显影剂粘附装置 已经形成潜像以形成可见图像，将形成在感光体上的可见图像转印到打印介质上的转印装置和将转印到打印介质上的可见图像熔合到打印介质的定影单元。 定影单元包括压辊，加热带，以紧密接触压辊，以形成定影辊隙，以将热和压力施加到已经转印有可见图像的打印介质上，彼此分开布置的第一和第二支撑辊 循环地支撑加热带，以及弹性支撑装置，用于沿着彼此远离的方向弹性地偏压第一支撑辊和/或第二支撑辊，以保持加热带的恒定张力。

公开(公告)号：US07547015B2

公开(公告)日：2009-06-16

申请号：US11296394

申请日：2005-12-08

申请人： Bong-hee Lee ,  Ho-min Lim

发明人： Bong-hee Lee ,  Ho-min Lim

IPC分类号： B65H31/04

CPC分类号： B65H31/02 ,  B65H31/20 ,  B65H2402/441 ,  B65H2405/111646 ,  B65H2801/06

摘要： An image forming apparatus has an image forming part forming an image on paper, and a housing accommodating the image forming part and having a paper stack part stacking paper discharged from the image forming part, and the image forming apparatus includes an accommodating part formed in an edge of the paper stack part and extending in a paper discharge direction; a base plate mounted in the accommodating part to be slidable in the paper discharge direction and a reverse direction opposite to the paper discharge direction; and a stopper hinge-coupled to the base plate to be tiltable among a stand up position where the stopper blocks paper discharged from the image forming part, a rear folding position where the stopper is folded onto the base plate and is at least partially accommodated in the paper stack part, and a front folding position where the stopper is folded in the paper discharge direction.

摘要翻译： 图像形成装置具有在纸上形成图像的图像形成部和容纳图像形成部的壳体，并且具有从图像形成部排出的纸叠部分堆放纸，并且图像形成装置包括形成在图像形成部中的容纳部 纸叠部分的边缘并沿排纸方向延伸; 安装在所述容纳部中的基板，能够沿所述排纸方向滑动，并且与所述排纸方向相反的方向; 以及止动器，其铰链连接到所述基板，以在所述止挡件阻挡从所述图像形成部件排出的纸张的立起位置之间倾斜，所述止动件折叠到所述基板上并且至少部分地容纳在所述底板中的后折叠位置 纸叠部分和止挡件沿排纸方向折叠的前折叠位置。

公开(公告)号：US20080286018A1

公开(公告)日：2008-11-20

申请号：US12105444

申请日：2008-04-18

申请人： Bong Hee Lee

发明人： Bong Hee Lee

IPC分类号： G03G15/20

CPC分类号： G03G15/2053 ,  G03G2215/2032

摘要： An image forming apparatus and a fusing unit thereof. The image forming apparatus includes a photosensitive body on which to form an electrostatic latent image, an exposure device to irradiate light to the photosensitive body to form the electrostatic latent image, a developer adhering device to adhere a developer to the photosensitive body on which the electrostatic latent image has been formed to form a visible image, a transfer device to transfer the visible image formed on the photosensitive body onto a printing medium, and a fusing unit to fuse the visible image transferred onto the printing medium to the printing medium. The fusing unit includes a press roller, a heating belt to closely contact the press roller to form a fusing nip to apply heat and pressure to the printing medium onto which the visible image has been transferred, first and second support rollers disposed apart from each other to circulatingly support the heating belt, and an elastic support device to elastically bias the first support roller and/or the second support roller in a direction away from each other to maintain a constant tension of the heating belt.

摘要翻译： 图像形成装置及其定影单元。 图像形成装置包括在其上形成静电潜像的感光体，将光照射到感光体以形成静电潜像的曝光装置，用于将显影剂粘附到静电的感光体上的显影剂粘附装置 已经形成潜像以形成可见图像，将形成在感光体上的可见图像转印到打印介质上的转印装置和将转印到打印介质上的可见图像熔合到打印介质的定影单元。 定影单元包括压辊，加热带，以紧密接触压辊，以形成定影辊隙，以将热和压力施加到已经转印有可见图像的打印介质上，彼此分开布置的第一和第二支撑辊 循环地支撑加热带，以及弹性支撑装置，用于沿着彼此远离的方向弹性地偏压第一支撑辊和/或第二支撑辊，以保持加热带的恒定张力。

公开(公告)号：US20060220303A1

公开(公告)日：2006-10-05

申请号：US11296394

申请日：2005-12-08

申请人： Bong-hee Lee ,  Ho-min Lim

发明人： Bong-hee Lee ,  Ho-min Lim

IPC分类号： B65H31/00

CPC分类号： B65H31/02 ,  B65H31/20 ,  B65H2402/441 ,  B65H2405/111646 ,  B65H2801/06

摘要： An image forming apparatus has an image forming part forming an image on paper, and a housing accommodating the image forming part and having a paper stack part stacking paper discharged from the image forming part, and the image forming apparatus includes an accommodating part formed in an edge of the paper stack part and extending in a paper discharge direction; a base plate mounted in the accommodating part to be slidable in the paper discharge direction and a reverse direction opposite to the paper discharge direction; and a stopper hinge-coupled to the base plate to be tiltable among a stand up position where the stopper blocks paper discharged from the image forming part, a rear folding position where the stopper is folded onto the base plate and is at least partially accommodated in the paper stack part, and a front folding position where the stopper is folded in the paper discharge direction.

公开(公告)号：US07035579B2

公开(公告)日：2006-04-25

申请号：US10673244

申请日：2003-09-30

申请人： Bong-hee Lee

发明人： Bong-hee Lee

IPC分类号： G03G15/20

CPC分类号： G03G15/2028

摘要： A sheet separating apparatus for a fusing unit separates a sheet being conveyed through a fusing unit from a heating roller and guides the sheet to a discharging roller without causing damages to a surface of a fusing roller. The sheet separating apparatus comprises a separating claw rotatably disposed toward a discharging side of a heating roller, for separating a sheet from the heating roller, and a contact spring pivoting the separating claw so that a front end of the separating claw is in contact with the heating roller with a predetermined constant pressure. The front end of the separating claw has rounded corners. It is preferred that the front end of the separating claw is chamfered. Also, it is preferred that the separating claw is made of stainless steel.

摘要翻译： 用于定影单元的片材分离装置将通过定影单元传送的片材与加热辊分离，并将片材引导到排出辊，而不会损坏定影辊的表面。 片材分离装置包括：分离爪，其可旋转地设置在加热辊的排放侧，用于将片材与加热辊分离;以及接触弹簧，其使分离爪枢转，使得分离爪的前端与 加热辊具有预定的恒定压力。 分离爪的前端有圆角。 优选的是，分离爪的前端被倒角。 此外，优选的是，分离爪由不锈钢制成。

公开(公告)号：US20060083546A1

公开(公告)日：2006-04-20

申请号：US11248129

申请日：2005-10-13

申请人： Bong-hee Lee

发明人： Bong-hee Lee

IPC分类号： G03G21/00

CPC分类号： G03G15/6529 ,  G03G2215/00544 ,  G03G2215/00548

摘要： An image forming apparatus includes a main body frame, an image forming unit disposed inside of the main body frame to form an image, a door unit disposed in such a manner to make a conjoin rotation to thereby approach to a paper transfer path disposed inside of the main body frame, a roller assembly disposed on the paper transfer path, and an opening and closing coupling unit to couple the door unit with the roller assembly, wherein the roller assembly is opened/closed when the door unit is opened/closed.

摘要翻译： 图像形成装置包括主体框架，设置在主体框架内部以形成图像的图像形成单元;门单元，其以这样的方式设置，使得结合旋转，从而接近设置在 主体框架，布置在纸张传送路径上的辊组件以及将门单元与辊组件连接的打开和关闭联接单元，其中当门单元打开/关闭时，辊组件被打开/关闭。

公开(公告)号：US20180066384A1

公开(公告)日：2018-03-08

申请号：US15561485

申请日：2016-03-22

申请人： Bong Hee LEE ,  Kyu Sang LEE

发明人： Bong Hee LEE ,  Kyu Sang LEE

IPC分类号： D01F1/10 ,  D01F1/09 ,  C01G3/12 ,  C01G3/10 ,  C01G3/05 ,  C07C211/09 ,  C07C211/13

CPC分类号： D01F1/10 ,  C01G3/05 ,  C01G3/10 ,  C01G3/12 ,  C07C211/09 ,  C07C211/13 ,  D01F1/09 ,  D06M11/53 ,  D06M11/56 ,  D06M13/332 ,  G01N21/3581

摘要： The present invention relates to a functional copper sulfide composition and a functional fiber prepared therefrom, and more particularly, a functional copper sulfide composition comprising a copper salt, a metal salt, a reducing agent, a sulfur compound, a catalyst, a polyvalent amine, an alkali compound and a pH adjusting agent; and a functional fiber prepared by treating the composition with a fiber.The present invention can provide a functional fiber with excellent conductivity, washing resistance, washability, durability, moisture resistance and alkali resistance, wherein the color of the fiber is maintained even when it is washed repeatedly or used for a long time.In addition, the present invention can provide a functional fiber which has excellent an antibacterial, deodorant, far-infrared radiation, wound healing, skin aging prevention, insulation, electromagnetic shielding and static electricity removal characteristics, and can be widely used in clothing, industrial and military field such as clothing, socks, gloves, bands, abdominal binder, masks, hats, bandage, scarf, bedclothes, burn pad, a hospital gown, an industrial filter and filler.

公开(公告)号：US20140106376A1

公开(公告)日：2014-04-17

申请号：US14059283

申请日：2013-10-21

申请人： Ki Young LEE ,  Bong Hee LEE ,  Kyung Hee BYUN ,  Sun Ha PAEK

发明人： Ki Young LEE ,  Bong Hee LEE ,  Kyung Hee BYUN ,  Sun Ha PAEK

IPC分类号： G01N33/68

CPC分类号： G01N33/6893 ,  G01N33/57407 ,  G01N2500/00

摘要： The present invention relates to a method for diagnosing glioma by comparing the protein location of an individual to be diagnosed with the normal control nerve cells. More particularly, the present invention relates to a method for diagnosing glioma including determining that an individual has glioma when the expression level of GFRα4 in the endoplasmic reticulum is higher than that in the plasma membrane, and a method for screening a therapeutic agent for glioma. In the diagnostic method of the present invention, the protein expression levels in particular subcellular locations are compared, thereby accurately diagnosing glioma, diagnosing progression of glioma, and predicting prognosis after glioma surgery.

摘要翻译： 本发明涉及通过比较待诊断个体与正常对照神经细胞的蛋白质位置来诊断胶质瘤的方法。 更具体地，本发明涉及当内质网中GFRα4的表达水平高于质膜时的神经胶质瘤诊断方法，包括确定个体具有神经胶质瘤，以及用于筛选胶质瘤治疗剂的方法。 在本发明的诊断方法中，比较特定亚细胞位置的蛋白质表达水平，从而精确诊断神经胶质瘤，诊断胶质瘤的进展，并预测胶质瘤手术后的预后。

公开(公告)号：US20120207524A1

公开(公告)日：2012-08-16

申请号：US13200984

申请日：2011-10-06

申请人： Jin-seok Lee ,  Bong-hee Lee ,  Sang-uk Jeon ,  Dong-kyun Kim

发明人： Jin-seok Lee ,  Bong-hee Lee ,  Sang-uk Jeon ,  Dong-kyun Kim

IPC分类号： G03G15/20

CPC分类号： G03G15/2028

摘要： A fusing apparatus to fuse a toner image transferred to a printing medium by applying heat and pressure. The fusing apparatus includes a separation member that is rotatably mounted on a rotation axis to separate the printing medium from one of a heating roller and a pressing roller. The separation member includes a hollow portion into which the rotation axis is inserted, and a separation portion that contacts an outer circumference of the heating roller. The separation member is installed so as to be pitched around the rotation axis and a pitching axis having an inclination angle within a range of ±10° with respect to a line that connects a contact point between the separation portion and the outer circumference of the roller from which the printing medium is to be separated and a center of the roller from which the printing medium is to be separated.

摘要翻译： 一种定影装置，通过施加热量和压力来熔化转印到打印介质上的调色剂图像。 定影装置包括：分离构件，其可旋转地安装在旋转轴线上，以将打印介质与加热辊和加压辊之一分离。 分离构件包括插入旋转轴线的中空部分和与加热辊的外圆周接触的分离部分。 分离构件安装成围绕旋转轴倾斜并且相对于连接分离部分和辊的外圆周之间的接触点的线具有在±10°范围内的倾斜角的俯仰轴 要从中分离打印介质和要从中分离打印介质的辊的中心。