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公开(公告)号：US20170233836A1
公开(公告)日：2017-08-17
申请号：US15433225
申请日：2017-02-15
CPC分类号： C14C13/00 , C08H1/06 , C08J3/24 , C08J2389/06 , C08L89/06 , C14C9/02 , D01D5/003 , D01D5/0053 , D01F4/00 , D02J1/04 , D04H1/728 , D06B19/007 , D06M10/00 , D06N3/0018 , D06P3/32
摘要： Biofabricated leathers made by electrocompaction and/or electrospsinning. Described herein are biofabricated leather materials derived from electrospun or electrocompacted collagen networks. These electrospun or electrocompacted leathers may have leather-like properties following and are may be processed as native leather and used to form leather goods.
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公开(公告)号：US09694081B2
公开(公告)日：2017-07-04
申请号：US13805501
申请日：2011-06-17
摘要： The invention relates to compositions comprising (i) biocompatible hydrogel and (ii) one or more therapeutic agents contained within said hydrogel; wherein the hydrogel is cross-linked utilizing a cross-linker comprising a peptide sequence that is capable of being degraded by an enzyme; the therapeutic agent being effective as a treatment of a condition related to the presence of the enzyme.
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公开(公告)号：US20150079238A1
公开(公告)日：2015-03-19
申请号：US14486850
申请日：2014-09-15
CPC分类号： C12N5/0658 , A23L13/00 , A23P10/20 , A23V2002/00 , C12N2500/92 , C12N2531/00 , A23V2200/264
摘要： Edible microcarriers, including microcarrier beads, microspheres and microsponges, appropriate for use in a bioreactor to culture cells that may be used to form a comestible engineered meat product. For example, the edible microcarriers described herein may include porous microcarriers that may be used to grow cells (e.g., smooth muscle cells) and may be included with the cells in the final engineered meat product, without requiring modification or removal of the cells from the microcarriers. In a particular example, the edible microcarriers may be formed of cross-linked pectin, such as pectin-thiopropionylamide (PTP), and RGD-containing polypeptide, such as thiolated cardosin A. Methods of forming edible microcarriers, methods of using the edible microcarriers to make engineered meat, and engineered meat including the edible microcarriers are also described herein.
摘要翻译： 适用于生物反应器的可食用微载体，包括微载体珠，微球和微球，可用于培养可用于形成可食用工程肉制品的细胞。 例如，本文所述的可食用微载体可以包括可用于生长细胞（例如平滑肌细胞）的多孔微载体，并且可以与最终工程化的肉制品中的细胞一起被包含，而不需要将细胞从 微载体 在具体实例中，可食用微载体可以由交联的果胶形成，例如果胶 - 硫代丙酰胺（PTP）和含RGD的多肽，例如硫苷化的心苷A.形成食用微载体的方法，使用可食用微载体的方法 制造工程肉和包括可食用微载体的工程肉也在本文中描述。
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公开(公告)号：US20140148395A1
公开(公告)日：2014-05-29
申请号：US13805501
申请日：2011-06-17
摘要： The invention relates to compositions comprising (i) biocompatible hydrogel and (ii) one or more therapeutic agents contained within said hydrogel; wherein the hydrogel is cross-linked utilizing a cross-linker comprising a peptide sequence that is capable of being degraded by an enzyme; the therapeutic agent being effective as a treatment of a condition related to the presence of the enzyme.
摘要翻译： 本发明涉及包含（i）生物相容性水凝胶和（ii）包含在所述水凝胶内的一种或多种治疗剂的组合物; 其中所述水凝胶使用包含能够被酶降解的肽序列的交联剂进行交联; 治疗剂作为与酶的存在相关的病症的治疗是有效的。
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