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公开(公告)号：US20130037485A1
公开(公告)日：2013-02-14
申请号：US13480444
申请日：2012-05-24
申请人： Michael J. Wilt , Dirk A. van der Merwe , Todd A. Ballantyne , Kevin L. Grant , Jonathan P. Rosse , Catharine N. Flynn , Brian K. Yee
发明人： Michael J. Wilt , Dirk A. van der Merwe , Todd A. Ballantyne , Kevin L. Grant , Jonathan P. Rosse , Catharine N. Flynn , Brian K. Yee
CPC分类号： A61M1/1601 , A61K33/00 , A61M1/1006 , A61M1/1037 , A61M1/1062 , A61M1/1087 , A61M1/1096 , A61M1/14 , A61M1/16 , A61M1/1605 , A61M1/1613 , A61M1/1619 , A61M1/1654 , A61M1/1656 , A61M1/1658 , A61M1/166 , A61M1/1664 , A61M1/1666 , A61M1/1668 , A61M1/1692 , A61M1/267 , A61M1/301 , A61M1/34 , A61M1/341 , A61M1/3413 , A61M1/3609 , A61M1/3621 , A61M1/3627 , A61M1/3638 , A61M1/3672 , A61M5/172 , A61M2205/12 , A61M2205/15 , A61M2205/18 , A61M2205/3306 , A61M2205/3313 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/3379 , A61M2205/3569 , A61M2205/3584 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2230/65 , G06F19/00 , G06F19/3481
摘要： Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and/or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and/or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations. Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid, may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and/or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.
摘要翻译： 公开了透析系统，其包括新的流体流动回路。 系统可以包括血液和透析液流动路径，其中透析液流动路径包括平衡，混合和/或引导电路。 透析液的制备可能与患者透析分离。 电路可以被定义在一个或多个盒中。 流体回路流体流动路径可以与电气部件隔离。 可以包括与透析液流路和/或透析器流体连通的能够通过透析器促进透析液并将血液推回到患者的气体供应用于某些紧急情况。 可以包括可以使用控制流体致动的流体处理装置，例如泵，阀和混合器。 控制流体可以由外部泵或其它装置输送，外部泵或其它装置可以是可拆卸的和/或大致刚性的，可选地具有将装置分隔成第一和第二隔室的隔膜。
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公开(公告)号：US20130020237A1
公开(公告)日：2013-01-24
申请号：US13480454
申请日：2012-05-24
申请人： Michael J. Wilt , Dirk A. van der Merwe , Todd A. Ballantyne , Kevin L. Grant , Johnathan P. Rosse , Catharine N. Flynn , Brian K. Yee
发明人： Michael J. Wilt , Dirk A. van der Merwe , Todd A. Ballantyne , Kevin L. Grant , Johnathan P. Rosse , Catharine N. Flynn , Brian K. Yee
IPC分类号： A61M1/14
CPC分类号： A61M1/1601 , A61K33/00 , A61M1/1006 , A61M1/1037 , A61M1/1062 , A61M1/1087 , A61M1/1096 , A61M1/14 , A61M1/16 , A61M1/1605 , A61M1/1613 , A61M1/1619 , A61M1/1654 , A61M1/1656 , A61M1/1658 , A61M1/166 , A61M1/1664 , A61M1/1666 , A61M1/1668 , A61M1/1692 , A61M1/267 , A61M1/301 , A61M1/34 , A61M1/341 , A61M1/3413 , A61M1/3609 , A61M1/3621 , A61M1/3627 , A61M1/3638 , A61M1/3672 , A61M5/172 , A61M2205/12 , A61M2205/15 , A61M2205/18 , A61M2205/3306 , A61M2205/3313 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/3379 , A61M2205/3569 , A61M2205/3584 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2230/65 , G06F19/00 , G06F19/3481
摘要： Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and/or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and/or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations. Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid, may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and/or generally rigid, optionally with a diaphragm, dividing the device into first and second compartments.
摘要翻译： 公开了透析系统，其包括新的流体流动回路。 系统可以包括血液和透析液流动路径，其中透析液流动路径包括平衡，混合和/或引导电路。 透析液的制备可能与患者透析分离。 电路可以被定义在一个或多个盒中。 流体回路流体流动路径可以与电气部件隔离。 可以包括与透析液流路和/或透析器流体连通的能够通过透析器促进透析液并将血液推回到患者的气体供应用于某些紧急情况。 可以包括可以使用控制流体致动的流体处理装置，例如泵，阀和混合器。 控制流体可以由外部泵或其他装置输送，外部泵或其它装置可以是可拆卸的和/或大致刚性的，可选地具有隔膜，将装置分成第一和第二隔室。
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公开(公告)号：US09717834B2
公开(公告)日：2017-08-01
申请号：US13480444
申请日：2012-05-24
申请人： Michael J. Wilt , Dirk A. van der Merwe , Todd A. Ballantyne , Kevin L. Grant , Jonathan P. Rosse , Catharine N. Flynn , Brian K. Yee
发明人： Michael J. Wilt , Dirk A. van der Merwe , Todd A. Ballantyne , Kevin L. Grant , Jonathan P. Rosse , Catharine N. Flynn , Brian K. Yee
IPC分类号： B01D61/30 , B01D61/28 , G01N21/59 , B01D61/32 , A61M1/16 , A61M5/172 , A61M1/14 , G06F19/00 , A61M1/10 , A61M1/34 , A61M1/36
CPC分类号： A61M1/1601 , A61K33/00 , A61M1/1006 , A61M1/1037 , A61M1/1062 , A61M1/1087 , A61M1/1096 , A61M1/14 , A61M1/16 , A61M1/1605 , A61M1/1613 , A61M1/1619 , A61M1/1654 , A61M1/1656 , A61M1/1658 , A61M1/166 , A61M1/1664 , A61M1/1666 , A61M1/1668 , A61M1/1692 , A61M1/267 , A61M1/301 , A61M1/34 , A61M1/341 , A61M1/3413 , A61M1/3609 , A61M1/3621 , A61M1/3627 , A61M1/3638 , A61M1/3672 , A61M5/172 , A61M2205/12 , A61M2205/15 , A61M2205/18 , A61M2205/3306 , A61M2205/3313 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/3379 , A61M2205/3569 , A61M2205/3584 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2230/65 , G06F19/00 , G06F19/3481
摘要： Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and/or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and/or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid, may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and/or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.
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公开(公告)号：US09517295B2
公开(公告)日：2016-12-13
申请号：US13480454
申请日：2012-05-24
申请人： Michael J. Wilt , Dirk A. van der Merwe , Todd A. Ballantyne , Kevin L. Grant , Jonathan P. Rosse , Catharine N. Flynn , Brian K. Yee
发明人： Michael J. Wilt , Dirk A. van der Merwe , Todd A. Ballantyne , Kevin L. Grant , Jonathan P. Rosse , Catharine N. Flynn , Brian K. Yee
CPC分类号： A61M1/1601 , A61K33/00 , A61M1/1006 , A61M1/1037 , A61M1/1062 , A61M1/1087 , A61M1/1096 , A61M1/14 , A61M1/16 , A61M1/1605 , A61M1/1613 , A61M1/1619 , A61M1/1654 , A61M1/1656 , A61M1/1658 , A61M1/166 , A61M1/1664 , A61M1/1666 , A61M1/1668 , A61M1/1692 , A61M1/267 , A61M1/301 , A61M1/34 , A61M1/341 , A61M1/3413 , A61M1/3609 , A61M1/3621 , A61M1/3627 , A61M1/3638 , A61M1/3672 , A61M5/172 , A61M2205/12 , A61M2205/15 , A61M2205/18 , A61M2205/3306 , A61M2205/3313 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/3379 , A61M2205/3569 , A61M2205/3584 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2230/65 , G06F19/00 , G06F19/3481
摘要： Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and/or directing circuits. Dialysis systems may include a safety system utilizing a field programmable gate array (FPGA) that monitors at least conductivity and temperature of dialysate in the flow circuit upstream of a dialyzer and enters a fail-safe state if the measured conductivity is outside of a range of values. The FPGA may be verified to be operating properly by exposing sensors in fluid paths to temperatures or conductivities that are outside pre-determined permissible ranges of values, and confirming that the FPGA safety system enters a fail-safe state in response to the temperatures or conductivities. The FPGA may be configured to monitor an amount of ultrafiltration fluid withdrawn from a patient during dialysis treatment and to enter a fail-safe state if a maximum amount is exceeded.
摘要翻译： 公开了透析系统，其包括新的流体流动回路。 系统可以包括血液和透析液流动路径，其中透析液流动路径包括平衡，混合和/或引导电路。 透析系统可以包括使用现场可编程门阵列（FPGA）的安全系统，其至少监测透析器上游的流动回路中透析液的电导率和温度，并且如果测量的电导率在 价值观。 可以通过将流体路径中的传感器暴露于超出预定的允许值范围的温度或电导率，并且确认FPGA安全系统响应于温度或电导率而进入故障安全状态，可以验证FPGA可以正常工作 。 FPGA可以被配置为监测在透析治疗期间从患者抽出的超滤流体的量，并且如果超过最大量则进入故障安全状态。
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