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公开(公告)号:US20050100894A1
公开(公告)日:2005-05-12
申请号:US10344165
申请日:2001-08-07
申请人: Burkhard Scharm
发明人: Burkhard Scharm
IPC分类号: G01N33/50 , A61K39/00 , A61P3/04 , A61P3/10 , A61P7/00 , A61P9/00 , A61P9/10 , A61P11/00 , A61P19/02 , A61P25/00 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P37/06 , A61P37/08 , C07K16/40 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/12 , C12N15/09 , C12N15/54 , C12N15/62 , C12Q1/02 , C12Q1/68 , G01N33/15 , G01N33/573 , C07H21/04 , C07K14/00
CPC分类号: C12N9/1205
摘要: MEKK3b polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing MEKK3b polypeptides and polynucleotides in diagnostic assays.
摘要翻译: 公开了MEKK3b多肽和通过重组技术产生这种多肽的多核苷酸和方法。 还公开了在诊断测定中利用MEKK3b多肽和多核苷酸的方法。
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公开(公告)号:US20070207506A1
公开(公告)日:2007-09-06
申请号:US11347380
申请日:2006-02-06
申请人: Klaus Ducker , Burkhard Scharm
发明人: Klaus Ducker , Burkhard Scharm
CPC分类号: C07K14/723 , C07K2319/00
摘要: ICSR-1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing ICSR-1 polypeptides and polynucleotides in diagnostic assays.
摘要翻译: 公开了ICSR-1多肽和通过重组技术产生这种多肽的多核苷酸和方法。 还公开了在诊断测定中利用ICSR-1多肽和多核苷酸的方法。
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公开(公告)号:US20060058516A1
公开(公告)日:2006-03-16
申请号:US10257143
申请日:2001-04-09
申请人: Burkhard Scharm , Detlef Gussow
发明人: Burkhard Scharm , Detlef Gussow
CPC分类号: C12N9/1205 , C07K2319/00
摘要: STK3 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing STK3 polypeptides and polynucleotides in diagnostic assays.
摘要翻译: 公开了STK3多肽和多核苷酸以及通过重组技术产生此类多肽的方法。 还公开了在诊断测定中利用STK3多肽和多核苷酸的方法。
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公开(公告)号:US20050244421A1
公开(公告)日:2005-11-03
申请号:US11010748
申请日:2004-12-13
IPC分类号: C12N15/09 , A61K35/12 , A61K38/00 , A61K39/00 , A61K39/39 , A61P35/00 , A61P35/02 , A61P37/06 , C07K7/06 , C07K7/08 , C07K14/47 , C07K16/18 , C12N5/10 , C12N15/10 , C12P21/08 , C12Q1/68 , G01N33/68
CPC分类号: G01N33/6845 , A61K2039/5156 , C12N15/1034 , G01N33/56977 , G01N33/574 , G01N2333/70539 , G01N2800/245 , G01N2800/56
摘要: A method of modulating reactivity of a T cell population of a mammal comprises contacting the T cell population with an immunogenic dose of an antigenic peptide having a sequence that derives from a tissue specific expressed allelic protein variant from an individual of a specific species, wherein the tissue specific expressed allelic protein is encoded by a DNA sequence containing at least one single nucleotide polymorphism (SNP) in the coding region and binds to a MHC class I protein complex inducing an immunogenic response.
摘要翻译: 调节哺乳动物T细胞群体的反应性的方法包括使T细胞群体与免疫原性剂量的抗原肽接触,所述抗原肽具有源自特定物种个体的组织特异性表达的等位基因蛋白质变体的序列,其中 组织特异性表达的等位基因蛋白由编码区中含有至少一个单核苷酸多态性(SNP)的DNA序列编码,并与诱导免疫原性应答的MHC I类蛋白复合物结合。
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公开(公告)号:US07091022B2
公开(公告)日:2006-08-15
申请号:US10344165
申请日:2001-08-07
申请人: Burkhard Scharm
发明人: Burkhard Scharm
CPC分类号: C12N9/1205
摘要: MEKK3b polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing MEKK3b polypeptides and polynucleotides in diagnostic assays.
摘要翻译: 公开了通过重组技术生产这种多肽的MEKK3b多肽和多核苷酸和方法。 还公开了在诊断测定中利用MEKK3b多肽和多核苷酸的方法。
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公开(公告)号:US07037699B2
公开(公告)日:2006-05-02
申请号:US10220858
申请日:2001-03-07
申请人: Simon Goodman , Burkhard Scharm , Marcus Frohme , Joerg Hoheisel
发明人: Simon Goodman , Burkhard Scharm , Marcus Frohme , Joerg Hoheisel
CPC分类号: C12N9/1205 , C07K2319/00
摘要: ERK-7 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing ERK-7 polypeptides and polynucleotides in diagnostic assays.
摘要翻译: 公开了通过重组技术产生这种多肽的ERK-7多肽和多核苷酸和方法。 还公开了在诊断测定中利用ERK-7多肽和多核苷酸的方法。
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