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公开(公告)号：US11621416B2
公开(公告)日：2023-04-04
申请号：US16754670
申请日：2018-09-27
Applicant: CSIR
Inventor： Hongze Luo , Nomasonto Rapulenyane , Bonani Seteni , Mkhulu Mathe
IPC: H01M4/505 , H01M10/0525 , H01M4/04
Abstract: A process for producing a lithium-manganese-rich layered oxide cathode material or a lithium-manganese-rich layered oxide cathode material precursor includes co-precipitating a dissolved Li compound and a dissolved Mn salt selected from the group consisting of Mn(CH3COO)2, Mn(NO3)2, MnSO4, and mixtures thereof, from an aqueous solution, in the presence of a precipitator which reacts at least with the dissolved Mn salt to form a carbonate, thereby providing a precipitate which includes MnCO3 and a lithium compound as a lithium-manganese-rich layered oxide cathode material precursor. The invention extends to a lithium-manganese-rich layered oxide cathode material or a lithium-manganese-rich layered oxide cathode material precursor, to an electrochemical cell, and to methods of making and operating an electrochemical cell.
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公开(公告)号：US11585751B2
公开(公告)日：2023-02-21
申请号：US16754683
申请日：2018-10-09
Applicant: CSIR
Inventor： Ettienne Cox
IPC: G01N21/3504 , G01M3/38 , G01N21/17
Abstract: This invention relates to a method of and system for facilitating detection of a particular predetermined gas in a scene under observation. The gas in the scene is typically associated with a gas leak in equipment. To this end, the system comprises an infrared camera arrangement; a strobing illuminator device having a strobing frequency matched to a frame rate of the camera; and a processing arrangement. The processing arrangement is configured to store a prior frame obtained via the infrared camera arrangement; and compare a current frame with the stored prior frame and generate an output signal in response to said comparison. The system also comprises a display device configured to display an output image based at least on the output signal generated by the processing arrangement so as to facilitate detection of the particular predetermined gas, in use.
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公开(公告)号：US11255644B2
公开(公告)日：2022-02-22
申请号：US16089877
申请日：2017-04-28
Applicant: CSIR
Inventor： Marius Olivier , Frederik Johannes Mostert
IPC: F41H11/136 , G01V11/00 , F41H11/02 , F41H5/007 , F41H7/02
Abstract: This invention related to a method of and system for detecting a threat, particularly a threat to a vehicle associated with an explosive blast and/or detonations. The method typically comprises receiving electromagnetic signals, or data indicative thereof, via a suitable electromagnetic detector arrangement from a target area adjacent the vehicle, as well as receiving optical signals, or data indicative thereof, via a suitable optical sensor arrangement also from a target area adjacent the vehicle. The method then comprises generating a threat detect output in response to receiving an optical signal indicative of a threat subsequent to receiving an electromagnetic signal indicative of a threat. The system typically implements the method as described. The invention also extends to a vehicle comprising a system in accordance with the invention.
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公开(公告)号：US10819461B2
公开(公告)日：2020-10-27
申请号：US15750959
申请日：2016-08-05
Applicant: UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG , CSIR
Inventor： Andrew Forbes , Angela Dudley , Carmelo Guadalupe Rosales Guzmán
IPC: H04J14/04 , H04B10/66 , H04B10/516 , H04J14/06 , H04J14/02
Abstract: The invention relates to optical communication methods and systems. In particular, the invention relates to an optical communication method and system which is configured to create a multiplexed beam from an incident beam, wherein the multiplexed beam comprises a predetermined number of spatial modes simultaneously generated and multiplexed together in a fashion that is independent of wavelength. The spatial modes have two degrees of spatial freedom. The multiplexed beam is de-multiplexed downstream from multiplexing thereof in the communication system in a simultaneous fashion independent of wavelength to yield the predetermined number of spatial mode. The modes are used in optical communication as channels or as bits in a bit (de) encoding scheme.
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公开(公告)号：US10351916B2
公开(公告)日：2019-07-16
申请号：US15962645
申请日：2018-04-25
Applicant: CSIR
Inventor： Jerolen Naidoo , Samantha Barichievy , Rethabile Khutlang , Musa M Mhlanga
IPC: A61K31/19 , C12Q1/6886 , C12N15/113 , A61K38/12 , A61K31/436 , A61K31/437 , A61K31/4439 , A61K31/454 , A61K31/475 , A61K31/495 , A61K31/496 , A61K31/501 , A61K31/5025 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/5377 , A61K31/675 , A61K31/713 , A61K33/24 , C12Q1/70 , A61K31/197 , A61K31/4709 , A61K31/58 , A61K31/7072 , C12N15/11
Abstract: The present invention relates to methods for the identification of anti-HIV miRNAs and anti-HIV pharmaceutical compounds using high-throughput screening methods, comprising: transfecting reporter cells with a panel of miRNAs, infecting the reporter cells with HIV, screening the cells to identify miRNAs that modulate HIV infection and identifying the specific pathways, nucleic acids and/or polypeptides that are targeted by the miRNAs. The invention further provides for the identification and screening of anti-HIV pharmaceutical compounds having known activity against the specific pathways, nucleic acids and/or polypeptides that are targeted by the miRNAs for efficacy in the treatment of HIV. The invention also provides for the use of miRNA mimics, miRNA inhibitors and pharmaceutical compounds (including oncology drugs and kinase inhibitors) in the treatment and/or prevention of HIV infection.
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Patent Agency Ranking
公开(公告)号：US20190119131A1
公开(公告)日：2019-04-25
申请号：US15568203
申请日：2015-08-17
Applicant: CSIR
Inventor： Masindi Vhahangwele , Wilson Mugera Gitari
Abstract: A process for the treatment of contaminated water (10) includes contacting the contaminated water with cryptocrystalline magnesite (14) thereby to remove one or more contaminants from the water. The invention extends to powdered cryptocrystalline magnesite with a particle size such that the powdered or particulate cryptocrystalline magnesite is able to pass through a 125 μm particle size sieve for use in the treatment of water.
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公开(公告)号：US10143691B2
公开(公告)日：2018-12-04
申请号：US15503610
申请日：2015-08-17
Applicant: CSIR
Inventor： Janine Scholefield , Jerolen Naidoo , Musa M Mhlanga , Samantha Barichievy
IPC: A61K31/5025 , A61K38/17 , A61K31/277 , A61K31/497 , A61K31/496
Abstract: The present invention relates to methods and compositions for modulating the control of apoptosis, specifically for modulating the interaction between hnRNP-K and lincRNA-p21 to induce or prevent apoptosis in the cell.
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公开(公告)号：US20180321236A1
公开(公告)日：2018-11-08
申请号：US15773889
申请日：2016-11-04
Applicant: UNIVERSITY OF PRETORIA , CSIR
Inventor： Jan Adrianus Verschoor , Ikechukwu Okeke , Lonji Kalombo , Yolandy Lemmer
IPC: G01N33/569 , G01N33/543
CPC classification number: G01N33/5695 , G01N33/54346 , G01N33/5438 , G01N2333/35 , G01N2469/20 , G01N2800/12
Abstract: The invention provides a method of diagnosing tuberculosis by using a novel antibody biomarker capturing vehicle, activating a screen-printed electrode using chemical and mechanical polishing, and immobilising mycolic acid antigen biomarkers on the activated electrode. The novel antibody biomarker capturing vehicle is produced by introducing isolated mycolic acid antigens of tuberculous mycobacterial origin onto an outer surface of a nanoparticle such that the mycolic acid antigens are presented as antibody biomarker capturing agents. The solvent resistant screen-printed electrode is activated by both chemically and mechanically polishing the electrode. The mycolic acid antigens are immobilised on the activated electrode by incubating the activated electrode with a mycolic acid-dimethylformamide solution to allow mycolic acid antigens to adsorb onto the activated electrode.
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9.发明申请公开(公告)号：US20180231409A1
公开(公告)日：2018-08-16
申请号：US15512380
申请日：2015-09-18
Applicant: CSIR
Inventor： Hartmut Johannes Ilgner
CPC classification number: G01F1/6847 , G01F1/56 , G01F1/74 , G01P13/006 , G05D7/0617
Abstract: A method of deriving a conclusion of the condition of slurry flow in a non-vertical conduit includes artificially generating a first locally heated spot on an interior surface of the conduit at the invert of the conduit and artificially generating a second locally heated spot on the interior surface of the conduit at a location angularly spaced from the first heated spot at an angular spacing of at least 90°. The temperatures of the heated spots are measured, obtaining first and second temperature values T1, T2. Electronically generated signals carrying the values T1, T2 are communicated to an electronic computing device. The computing device automatically calculates a first temperature difference T1 minus T2 and automatically derives a conclusion of the condition of slurry flow prevailing in the conduit based on the relationship between the value of the first temperature difference and a first reference parameter.
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10.发明申请公开(公告)号：US20180159291A1
公开(公告)日：2018-06-07
申请号：US15827207
申请日：2017-11-30
Applicant: CSIR
Inventor： Ihar Anatolievich LITVIN , Gary Rees KING
CPC classification number: H01S3/0071 , H01S3/094049 , H01S3/094061 , H01S3/09408 , H01S3/094096 , H01S3/09415 , H01S3/102 , H01S3/1022
Abstract: A laser apparatus has a gain medium which has opposite ends, wherein the laser apparatus includes at least two independently controllable excitation sources, each one of the excitation sources being operable to produce an input beam to excite or pump the gain medium. Beam splitting arrangements are associated with the excitation sources are configured to split the input beam of its associated excitation source into at least two sub-beams. Beam guiding arrangements are associated with the excitation sources and are configured to direct a path of at least one of the split sub-beams from its associated excitation source, whereby each excitation source, its associated beam splitting arrangement, and beam guiding arrangement are arranged such that the sub-beams are respectively directed inwardly towards the gain medium at opposite ends.
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